The cheapest and fastest buses from Chicago, IL to Key West, FL
Cheapest price
$230
Average price
$230
Fastest journey
1 d 14 h 30 m
Average duration
1 d 14 h 30 m
Buses per day
1
Distance
1998 km
The best way to find a cheap bus ticket from Chicago, IL to Key West, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to Key West, FL will cost around $230 if you buy it on the day, but the cheapest tickets can be found for only $230.
Of the 1 buses that leave Chicago, IL for Key West, FL on Thu, Nov 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 06 the direct buses cover the 1998 km distance in an average of 1 d 14 h 30 m but if you time it right, some buses will get you there in just 1 d 14 h 30 m .
On Thu, Nov 06 the slowest buses will take 1 d 14 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Compare prices and tickets Chicago, IL to Key West, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
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Nov 12
Journey information
Overview: Bus from Chicago, IL to Key West, FL
Distance 1241 miles (1998 km) |
Average bus duration 46h 40m |
Cheapest ticket price $516 (€422) |
Buses per day 5 |
Fastest bus 46h 40m |
First bus 10:00 |
Last bus 17:00 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Chicago, IL to Key West, FL start from as low as $516 (€422) if booked well in advance.
- Standard Fares: Typically, trains cost $516 (€422) depending on the train type and class.
Bus providers: FlixBus from Chicago, IL to Key West, FLYou can travel by bus between Chicago, IL to Key West, FL with FlixBus for as low as $516 (€422). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Chicago, IL to Key West, FL

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Chicago, IL to Key West, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
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