Chicago, IL to Key West, FL bus with FlixBus

Wed, Feb 04
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The cheapest and fastest buses from Chicago, IL to Key West, FL

Showing times and prices for Feb 05

Cheapest price

$237

Average price

$237

Fastest journey

1 d 14 h 30 m

Average duration

1 d 14 h 30 m

Buses per day

1

Distance

1998 km

Cheap tickets

The best way to find a cheap bus ticket from Chicago, IL to Key West, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Chicago, IL to Key West, FL will cost around $237 if you buy it on the day, but the cheapest tickets can be found for only $237.

Fast buses

Of the 1 buses that leave Chicago, IL for Key West, FL on Thu, Feb 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Thu, Feb 05 the direct buses cover the 1998 km distance in an average of 1 d 14 h 30 m but if you time it right, some buses will get you there in just 1 d 14 h 30 m .

On Thu, Feb 05 the slowest buses will take 1 d 14 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
11:00PM38h30
Chicago, IL
01:30PMKey West, FL
$2371One-way
0 transfers

Compare prices and tickets Chicago, IL to Key West, FL by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Feb 05
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Feb 11

Why should you book Chicago, IL to Key West, FL buses with Omio?

FlixBus operates all buses services from Chicago, IL to Key West, FL.
Omio is an official ticket reseller for all your travel options from Chicago, IL to Key West, FL.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of to find the best option for your trip from Chicago, IL to Key West, FL.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Chicago, IL to Key West, FL.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Chicago, IL to Key West, FL.

Journey information

Overview: Bus from Chicago, IL to Key West, FL

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Buses from Chicago, IL to Key West, FL run on average 5 times per day, taking around 46h 40m. Cheap bus tickets for this journey start at $531 (€422) if you book in advance.

The earliest bus runs at 10:00, the last at 17:00. The fastest bus covers the 1241 miles (1998 km) distance in 46h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1241 miles (1998 km)
Average bus duration
46h 40m
Cheapest ticket price
$531 (€422)
Buses per day
5
Fastest bus
46h 40m
First bus
10:00
Last bus
17:00
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Chicago, IL to Key West, FLYou can travel by bus between Chicago, IL to Key West, FL with FlixBus for as low as $531 (€422). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
38h 30m
Cheapest Price
$146 (€116)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from Chicago, IL to Key West, FL

Find answers to the most common questions about traveling from Chicago, IL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Chicago, IL to Key West, FL can start from as little as $531 (€422) when you book in advance. The average bus ticket price for Chicago, IL to Key West, FL is $531 (€422) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Chicago, IL to Key West, FL is 46h 40m to travel the 1241 miles (1998 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Chicago, IL to Key West, FL leaves at 10:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Chicago, IL to Key West, FL leaves at 5:00 PM.
There are 5 buses a day from Chicago, IL to Key West, FL which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Chicago, IL to Key West, FL, you can count on FlixBus for the best way to get you to Key West, FL. You can also check all possible bus companies who offer a service between Chicago, IL and Key West, FL and compare the amenities they offer before buying a bus ticket.
A trip to Key West, FL from Chicago, IL is worth doing but not as a day trip with a journey time of 46h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Chicago, IL to Key West, FL is December.
It's helpful to compare your options as there are 2 ways to travel between Chicago, IL and Key West, FL including taking a bus and flight.
Yes, there are bathrooms on board the bus from Chicago, IL to Key West, FL for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from Chicago, IL to Key West, FL:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Some of the most interesting sights to explore in Key West, FL are:
  • Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
  • Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
  • Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
  • Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
  • Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
The best things to do in Key West, FL include:
  • Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
  • Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
  • Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
  • Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
  • Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
Whether you can cancel your bus ticket from Chicago, IL to Key West, FL depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Chicago, IL to Key West, FL.
Yes, the following luggage options are included when booking a bus ticket from Chicago, IL to Key West, FL:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Chicago, IL to Key West, FL:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Chicago, IL to Key West, FL. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Chicago, IL to Key West, FL with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Chicago, IL to Key West, FL with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Chicago, IL to Key West, FL with the following bus company: FlixBus.

popular bus stations

Popular bus stations from Chicago, IL to Key West, FL

Chicago
Key West
The major bus station for departures in Chicago is Chicago, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Chicago, Greyhound Bus Station for your trip from Chicago to Key West.
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information

More options for your journey from Chicago, IL to Key West, FL

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