4.9
4.6
Travel Information
Compare bus and flight for Harrisburg, PA to Key West, FL
Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to Key West, FL among Omio's users. If you are prioritising price take the bus with prices starting from $286. For those with little time consider booking a flight which can get you there in 8h 36m. The ticket price range depends on the travel mode: a bus costs an average of $286, and a flight costs an average of $427.
Distance: 1122 miles (1806 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$286 Average price Cheapest | $427 Average price | $267 Average price (fuel + tolls) |
43h 30m Average total duration 43h 0m Onboard + 30m Additional time* | 11h 36m Average total duration Fastest 8h 36m Onboard + 3h 0m Additional time* | 20h 2m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Harrisburg, PA to Key West, FL:
A bus is $141 (€116) less than a flight for this route with tickets for a flight from Harrisburg, PA to Key West, FL costing on average $427 (€350).
Other travel options to Key West, FL take longer:
Bus takes on average 43h 0m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Harrisburg, PA to Key West, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:30PM | Arrival Time 01:02PM | Duration 48h32 | Departure days Wed, Thu, Fri | Cheapest price $260 |
Operator Greyhound | Departure Time 06:30PM | Arrival Time 01:30PM | Duration 43h00 | Departure days Sat | Cheapest price $286 |
Live departures
Harrisburg, PA to Key West, FL bus times
The table below shows live departures for Harrisburg, PA to Key West, FL buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 6:30 PM Harrisburg, PA | 43h00 | 1:30 PM Key West, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to Key West, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 21
Jun 22
Jun 23
Jun 24
Jun 25
Jun 26
Jun 27
Why should you book Harrisburg, PA to Key West, FL buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Harrisburg, PA to Key West, FL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Harrisburg, PA to Key West, FL.
Journey information
Overview: Bus from Harrisburg, PA to Key West, FL
USAUSA
Buses from Harrisburg, PA to Key West, FL run on average 2 times per day, taking around 43h 0m. Cheap bus tickets for this journey start at $286 (€234) if you book in advance.
The earliest bus runs at 18:30, the last at 18:30. The fastest bus covers the 1122 miles (1806 km) distance in 43h 0m.
Distance 1122 miles (1806 km) |
Average bus duration 43h 0m |
Cheapest ticket price $286 (€234) |
Buses per day 2 |
Fastest bus 43h 0m |
First bus 6:30 PM |
Last bus 6:30 PM |
Cheapest Month Apr |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Oct - Dec |
Bus providers: Greyhound from Harrisburg, PA to Key West, FLYou can travel by bus between Harrisburg, PA to Key West, FL with Greyhound for as low as $286 (€234). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Harrisburg, PA to Key West, FL
Find answers to the most common questions about traveling from Harrisburg, PA to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Harrisburg, PA to Key West, FL
Most Harrisburg, PA to Key West, FL buses use the Harrisburg, Market St (Bus Station) to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Harrisburg, PA and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Harrisburg, Market St (Bus Station) from Harrisburg city centre
Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to Key West, FL
Here are some other resources that might have the information you need
Most popular buses to and from Key West, FL and Harrisburg, PA
Most popular bus connections to Key West, FL
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
