- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price
$168
Average price
$187
Fastest journey
1 d 9 h 55 m
Average duration
1 d 11 h 35 m
Buses per day
8
Distance
1385 km
The best way to find a cheap bus ticket from Frankfurt am Main to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Palermo will cost around $187 if you buy it on the day, but the cheapest tickets can be found for only $168.
It's difficult to get from Frankfurt am Main to Palermo without transferring at least once.
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FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Frankfurt am Main to Palermo among Omio's users. If you are prioritising price take the flight with prices starting from $50. For those with little time consider booking a flight which can get you there in 2h 51m. The ticket price range depends on the travel mode: a flight costs an average of $50, and a train costs an average of $435.
Distance: 860 miles (1385 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$190 Average price | $185 Average price Cheapest | $435 Average price | $327 Average price (fuel + tolls) |
32h 48m Average total duration 32h 18m Onboard + 30m Additional time* | 5h 51m Average total duration Fastest 2h 51m Onboard + 3h 0m Additional time* | 24h 28m Average total duration 23h 58m Onboard + 30m Additional time* | 22h 1m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frankfurt am Main to Palermo:
A flight is $5 (€4) less than a bus for this route with tickets for a bus from Frankfurt am Main to Palermo costing on average $190 (€153).
A flight is $250 (€201) less than a train for this route with tickets for a train from Frankfurt am Main to Palermo costing on average $435 (€350).
Other travel options to Palermo take longer:
Train takes on average 23h 58m.
Bus takes on average 32h 18m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 11:00AM | Duration 34h15 | Departure days Everyday | Cheapest price $158 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 11:00AM | Duration 33h55 | Departure days Everyday | Cheapest price $153 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 03:15PM | Duration 38h00 | Departure days Everyday | Cheapest price $152 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 03:15PM | Duration 37h35 | Departure days Everyday | Cheapest price $160 |
Operator FlixBus | Departure Time 08:03PM | Arrival Time 11:00AM | Duration 38h57 | Departure days Everyday | Cheapest price $160 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 11:00AM | Duration 36h15 | Departure days Everyday | Cheapest price $160 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 11:00AM | Duration 35h55 | Departure days Everyday | Cheapest price $156 |
The table below shows live departures for Frankfurt am Main to Palermo buses for today, Sunday, August 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixTrain+ FlixBus · FlixBus · FlixBus | 8:03 PM Frankfurt South station | 38h57 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 3 transfers | |
FlixBus · FlixBus · FlixBus | 10:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 36h15 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 35h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
| Monday, August 24 | |||||
FlixBus · FlixBus | 12:45 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 34h15 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 1:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 33h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 38h00 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:40 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 37h35 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frankfurt am Main to Palermo run on average 6 times per day, taking around 32h 18m. Cheap bus tickets for this journey start at $133 (€107) but you can travel from only $50 (€40) by flight.
The earliest bus runs at 00:20, the last at 23:05. The fastest bus covers the 860 miles (1385 km) distance in 33h 15m.
Distance 860 miles (1385 km) |
Average bus duration 32h 18m |
Cheapest ticket price $133 (€107) |
Buses per day 6 |
Fastest bus 33h 15m |
First bus 12:20 AM |
Last bus 11:05 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Mon |
Best time to book 49 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Find answers to the most common questions about traveling from Frankfurt am Main to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main to Palermo buses use the Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Frankfurt am Main and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
Frankfurt am Main, Hauptbahnhof is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Hauptbahnhof has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food outlets and cafes are inside the station.
Free Wi-Fi is available throughout the station. ATMs are aTMs are located near the main entrance.
Ticket office support is available at Frankfurt am Main, Hauptbahnhof.
Available at Frankfurt am Main, Hauptbahnhof: Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Hauptbahnhof: The station is fully accessible to wheelchair users.
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