The cheapest and fastest buses from Frankfurt am Main to Palermo
Cheapest price
$124
Average price
$153
Fastest journey
1 d 9 h 55 m
Average duration
1 d 11 h 45 m
Buses per day
5
Distance
1385 km
The best way to find a cheap bus ticket from Frankfurt am Main to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Palermo will cost around $153 if you buy it on the day, but the cheapest tickets can be found for only $124.
Of the 5 buses that leave Frankfurt am Main for Palermo on Tue, Feb 24, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Feb 24 the direct buses cover the 1385 km distance in an average of 1 d 11 h 45 m but if you time it right, some buses will get you there in just 1 d 9 h 55 m .
On Tue, Feb 24 the slowest buses will take 1 d 14 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train, bus, and flight for Frankfurt am Main to Palermo
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from €75. For those with little time consider booking a flight which can get you there in 2h 59m. The ticket price range depends on the travel mode: a bus costs an average of €75, and a train costs an average of €371.
Distance: 860 miles (1385 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€131 Average price Cheapest | €199 Average price | €389 Average price |
33h 6m Average total duration 32h 36m Onboard + 30m Additional time* | 5h 59m Average total duration Fastest 2h 59m Onboard + 3h 0m Additional time* | 24h 28m Average total duration 23h 58m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Frankfurt am Main to Palermo Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 11:00AM | Duration 34h15 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $135 |
Operator FlixBus | Departure Time 12:50AM | Arrival Time 01:55PM | Duration 37h05 | Departure days Mon, Sun | Cheapest price $140 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 11:00AM | Duration 33h55 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $131 |
Operator Infobus | Departure Time 05:20AM | Arrival Time 02:35PM | Duration 33h15 | Departure days Sun | Cheapest price $263 |
Operator FlixBus | Departure Time 07:45PM | Arrival Time 11:00AM | Duration 39h15 | Departure days Wed | Cheapest price $141 |
Operator FlixBus | Departure Time 08:03PM | Arrival Time 11:00AM | Duration 38h57 | Departure days Mon, Wed, Thu, Fri | Cheapest price $128 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 11:00AM | Duration 38h30 | Departure days Wed | Cheapest price $132 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 11:00AM | Duration 36h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $125 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 11:00AM | Duration 35h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $118 |
Live departures
Frankfurt am Main to Palermo bus times
The table below shows live departures for Frankfurt am Main to Palermo buses for today, Monday, February 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets | |
|---|---|---|---|---|---|---|
FlixTrain+ FlixBus · FlixBus | 7:03 PM Frankfurt South station | 38h57 | 10:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | ||
FlixBus · FlixBus · FlixBus | 9:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 36h15 | 10:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | ||
FlixBus · FlixBus · FlixBus | 10:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 35h55 | 10:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | ||
| Tuesday, February 24 | ||||||
![]() | 12:05 AM Frankfurt am Main | 33h55 | 10:00 AM Palermo | 0 transfersDirect | ||
This is the last bus of the day. | ||||||
Find all the dates and times for this journey
Compare prices and tickets Frankfurt am Main to Palermo by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 24
Feb 25
Feb 26
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Feb 28
Mar 01
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Why should you book Frankfurt am Main to Palermo buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Infobus to find the best option for your trip from Frankfurt am Main to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Frankfurt am Main to Palermo.
Why book with Omio over Wanderu, Trainline or Busbud?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Frankfurt am Main to Palermo.
Journey information
Overview: Bus from Frankfurt am Main to Palermo
Buses from Frankfurt am Main to Palermo run on average 4 times per day, taking around 32h 36m. Cheap bus tickets for this journey start at $94 (€75) but you can travel from only $24 (€19) by flight.
The earliest bus runs at 00:20, the last at 23:05. The fastest bus covers the 860 miles (1385 km) distance in 33h 15m.
Distance 860 miles (1385 km) |
Average bus duration 32h 36m |
Cheapest ticket price $94 (€75) |
Buses per day 4 |
Fastest bus 33h 15m |
First bus 00:20 |
Last bus 23:05 |
Bus providers: FlixBus, Infobus from Frankfurt am Main to PalermoYou can travel by bus between Frankfurt am Main to Palermo with FlixBus, Infobus for as low as $24 (€19). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
FAQs: Bus from Frankfurt am Main to Palermo
Find answers to the most common questions about traveling from Frankfurt am Main to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
- Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
- Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
- Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
- Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
- Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
- Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
- Explore the vibrant street art in the Vucciria district
- Take a cooking class to learn how to make traditional Sicilian dishes
- Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Frankfurt am Main to Palermo
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
Most popular bus connections from Frankfurt am Main
More options for your journey from Frankfurt am Main to Palermo
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