- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price on Oct 08
$138
Average ticket price on Oct 08
$143
Fastest journey on Oct 08
1 d 9 h 55 m
Average journey duration on Oct 08
1 d 11 h 35 m
Buses on Oct 08
7
Distance
1385 km
The best way to find a cheap bus ticket from Frankfurt am Main to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Palermo will cost around $143 if you buy it on the day, but the cheapest tickets can be found for only $138.
It's difficult to get from Frankfurt am Main to Palermo without transferring at least once.
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FlixBus · FlixBus · FlixBusBuses from Frankfurt am Main to Palermo run on average 6 times per day, taking around 32h 15m. Cheap bus tickets for this journey start at $90 (€75) but you can travel from only $30 (€25) by flight.
The earliest bus runs at 00:20, the last at 23:05. The fastest bus covers the 860 miles (1385 km) distance in 31h 15m.
Distance 860 miles (1385 km) |
Average bus duration 32h 15m |
Cheapest ticket price $90 (€75) |
Buses per day 6 |
Fastest bus 31h 15m |
First bus 12:20 AM |
Last bus 11:05 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Tue |
Best time to book 42 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 11:00AM | Duration 34h15 | Departure days Everyday | Cheapest price $134 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 11:00AM | Duration 33h55 | Departure days Everyday | Cheapest price $129 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 03:15PM | Duration 38h00 | Departure days Everyday | Cheapest price $130 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 03:15PM | Duration 37h35 | Departure days Everyday | Cheapest price $135 |
Operator OneBus | Departure Time 05:20AM | Arrival Time 02:35PM | Duration 33h15 | Departure days Sun | Cheapest price $229 |
Operator FlixBus | Departure Time 04:03PM | Arrival Time 11:00AM | Duration 42h57 | Departure days Sat | Cheapest price $165 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 11:00AM | Duration 39h00 | Departure days Wed | Cheapest price $128 |
Operator FlixBus | Departure Time 08:03PM | Arrival Time 11:00AM | Duration 38h57 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $135 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 11:00AM | Duration 38h50 | Departure days Tue | Cheapest price $145 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 11:00AM | Duration 38h30 | Departure days Wed | Cheapest price $153 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 11:00AM | Duration 38h25 | Departure days Tue | Cheapest price $124 |
Operator FlixBus | Departure Time 09:15PM | Arrival Time 03:15PM | Duration 42h00 | Departure days Tue, Wed | Cheapest price $138 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 11:00AM | Duration 36h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $133 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 11:00AM | Duration 35h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $133 |
The table below shows live departures for Frankfurt am Main to Palermo buses for today, Wednesday, October 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 8:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 39h00 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixTrain+ FlixBus · FlixBus · FlixBus | 8:03 PM Frankfurt South station | 38h57 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 3 transfers | |
FlixTrain+ FlixBus · FlixBus · FlixBus | 8:03 PM Frankfurt South station | 38h57 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 3 transfers | |
FlixBus · FlixBus · FlixBus | 8:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 38h30 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:15 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 42h00 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus | 12:45 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 34h15 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 1:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 33h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 38h00 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:40 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 37h35 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Find answers to the most common questions about traveling from Frankfurt am Main to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main to Palermo buses use the Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Frankfurt am Main and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
Frankfurt am Main, Hauptbahnhof is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Hauptbahnhof has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food outlets and cafes are inside the station.
Free Wi-Fi is available throughout the station. ATMs are aTMs are located near the main entrance.
Ticket office support is available at Frankfurt am Main, Hauptbahnhof.
Available at Frankfurt am Main, Hauptbahnhof: Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Hauptbahnhof: The station is fully accessible to wheelchair users.
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