- Must visit
Palazzo Abatellis - Regional Gallery of Sicily
Major art museum in a Gothic-Catalan palace, known for Antonello da Messina's works and important Sicilian medieval and Renaissance art.
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The cheapest and fastest buses from Frankfurt am Main to Palermo
Showing times and prices for May 25
Cheapest price
$194
Average price
$219
Fastest journey
1 d 9 h 55 m
Average duration
1 d 11 h 35 m
Buses per day
7
Distance
1385 km
Cheap tickets
The best way to find a cheap bus ticket from Frankfurt am Main to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Palermo will cost around $219 if you buy it on the day, but the cheapest tickets can be found for only $194.
Fast buses
It's difficult to get from Frankfurt am Main to Palermo without transferring at least once.
FlixBus · FlixBus · FlixBus1:15 AM38h00Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$1941One-way2 transfers- FlixBus · FlixBus · FlixBus11:05 PM35h55Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$2081One-way2 transfers
FlixTrain+FlixBus · FlixBus · FlixBus8:03 PM38h57Frankfurt South station11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$2091One-way3 transfers- FlixBus · FlixBus · FlixBus1:40 AM37h35Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$2111One-way2 transfers
- FlixBus · FlixBus · FlixBus10:45 PM36h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$2271One-way2 transfers
- FlixBus · FlixBus1:05 AM33h55Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$2341One-way1 transfer
- FlixBus · FlixBus12:45 AM34h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$2481One-way1 transfer
- FlixBus · FlixBus · FlixBus11:05 PM35h55Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$2081One-way2 transfers
- FlixBus · FlixBus · FlixBus10:45 PM36h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$2271One-way2 transfers
- FlixBus · FlixBus · FlixBus1:40 AM37h35Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$2111One-way2 transfers
Travel Information
Compare train, bus, and flight for Frankfurt am Main to Palermo
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $97. For those with little time consider booking a flight which can get you there in 2h 59m. The ticket price range depends on the travel mode: a bus costs an average of $97, and a train costs an average of $434.
Distance: 860 miles (1385 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$165 Average price Cheapest | $242 Average price | $434 Average price | $323 Average price (fuel + tolls) |
33h 7m Average total duration 32h 37m Onboard + 30m Additional time* | 5h 59m Average total duration Fastest 2h 59m Onboard + 3h 0m Additional time* | 24h 28m Average total duration 23h 58m Onboard + 30m Additional time* | 22h 1m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Frankfurt am Main to Palermo is a bus with an average price of $165 (€133).
This is compared to other travel options from Frankfurt am Main to Palermo:
A bus is $77 (€62) less than a flight for this route with tickets for a flight from Frankfurt am Main to Palermo costing on average $242 (€195).
A bus is $269 (€217) less than a train for this route with tickets for a train from Frankfurt am Main to Palermo costing on average $434 (€350).
The fastest way to travel from Frankfurt am Main to Palermo is by flight with an average journey time of 2h 59m.
Other travel options to Palermo take longer:
Train takes on average 23h 58m.
Bus takes on average 32h 37m.
It's helpful to compare your options as there are 3 ways to travel between Frankfurt am Main and Palermo including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Frankfurt am Main to Palermo among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $165 (€133) compared to roughly $323 (€261) in fuel and tolls — a saving of about $158 (€128). The journey takes 32h 37m versus 22h 1m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Frankfurt am Main to Palermo Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 11:00AM | Duration 34h15 | Departure days Everyday | Cheapest price $148 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 11:00AM | Duration 33h55 | Departure days Everyday | Cheapest price $143 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 03:15PM | Duration 38h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $153 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 03:15PM | Duration 37h35 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $163 |
Operator Infobus | Departure Time 05:20AM | Arrival Time 02:35PM | Duration 33h15 | Departure days Sun | Cheapest price $237 |
Operator FlixBus | Departure Time 06:03PM | Arrival Time 11:00AM | Duration 40h57 | Departure days Wed, Fri | Cheapest price $106 |
Operator FlixBus | Departure Time 08:03PM | Arrival Time 11:00AM | Duration 38h57 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $162 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 11:00AM | Duration 36h15 | Departure days Everyday | Cheapest price $124 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 11:00AM | Duration 35h55 | Departure days Everyday | Cheapest price $118 |
Live departures
Frankfurt am Main to Palermo bus times
The table below shows live departures for Frankfurt am Main to Palermo buses for tomorrow, Monday, May 25. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus | 1:40 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 37h35 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
| FlixTrain+FlixBus · FlixBus · FlixBus | 8:03 PM Frankfurt South station | 38h57 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 3 transfers | |
| FlixBus · FlixBus · FlixBus | 10:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 36h15 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 35h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Frankfurt am Main to Palermo by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Frankfurt am Main to Palermo buses with Omio?
FlixBus as well as Infobus offer buses services from Frankfurt am Main to Palermo.
Omio is an official ticket reseller for all your travel options from Frankfurt am Main to Palermo.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Infobus to find the best option for your trip from Frankfurt am Main to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Frankfurt am Main to Palermo.
Why book with Omio over Wanderu, Trainline or Busbud?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Frankfurt am Main to Palermo.
Journey information
Overview: Bus from Frankfurt am Main to Palermo
Germany
Italy
Buses from Frankfurt am Main to Palermo run on average 5 times per day, taking around 32h 37m. Cheap bus tickets for this journey start at $97 (€78) but you can travel from only $24 (€19) by flight.
The earliest bus runs at 00:20, the last at 23:05. The fastest bus covers the 860 miles (1385 km) distance in 33h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $24 (€19)
Distance 860 miles (1385 km) |
Average bus duration 32h 37m |
Cheapest ticket price $97 (€78) |
Buses per day 5 |
Fastest bus 33h 55m |
First bus 12:20 AM |
Last bus 11:05 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 49 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $24 (€19)
Bus providers: FlixBus, Infobus from Frankfurt am Main to PalermoYou can travel by bus between Frankfurt am Main to Palermo with FlixBus, Infobus for as low as $24 (€19). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
33h 55m
Cheapest Price
$97 (€78)
FlixBus frequency
6 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Infobus
About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Average Duration
33h 15m
Cheapest Price
$224 (€181)
Infobus frequency
1 a day
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.
Complete guide to Palermo
Things to do in Palermo
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
- Recommended
Antonino Salinas Regional Archaeological Museum
Leading archaeological museum with Punic, Greek and Roman finds, plus one of the most important classical collections in Sicily.
- Recommended
Palazzo Mirto
Historic house museum preserving aristocratic interiors, decorative arts and furnishings that show Palermo's noble life across centuries.
- Must visit
Quattro Canti
Baroque crossroads at the heart of historic Palermo, famous for its theatrical facades and constant street life.
- Must visit
Piazza Pretoria
Elegant square known for its monumental Renaissance fountain and surrounding historic buildings in the old center.
- Must visit
Mondello Beach Area
The city's famous seaside district, popular for clear water, Liberty-style architecture and a social-media-friendly coastal setting.
Arancine
Palermo’s iconic fried rice balls, often filled with ragù, butter and ham, or cheese. A classic street food and a point of local pride.
- Vegetarian
- Vegan
Panelle
Chickpea fritters served hot, often in a sesame bun. One of Palermo’s most traditional and beloved street foods.
- Vegetarian
Crocchè
Soft potato croquettes, usually mixed with parsley and fried until crisp. Commonly eaten with panelle in Palermo street food shops.
Osteria Ballarò
Well-known restaurant near the historic center serving refined Sicilian cuisine with local ingredients in an elegant but welcoming atmosphere.
Buatta Cucina Popolana
Popular modern Sicilian restaurant focused on traditional recipes, seasonal produce, and polished presentations in central Palermo.
Trattoria Ai Cascinari
Established family-run trattoria loved for hearty Palermitan cooking, generous portions, and a classic local dining atmosphere.
Euro
Generally cheaper than Rome or Milan. Meals and transport are reasonable, while central hotels cost more in peak season.
Average meal costs
- Budget
- EUR 8-15 for street food or a simple lunch.
- Mid-range
- EUR 20-35 per person at a casual restaurant.
- Fine dining
- EUR 60+ per person at upscale restaurants.
- Coffee
- EUR 1.20-3 for espresso or cappuccino.
Tipping culture
Service is often included or minimal. Tipping is not required, but rounding up or leaving 5-10% for very good restaurant service is appreciated. Round up taxi fares.
FAQs: Bus from Frankfurt am Main to Palermo
Find answers to the most common questions about traveling from Frankfurt am Main to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Frankfurt am Main to Palermo can start from as little as $97 (€78) when you book in advance. The average bus ticket price for Frankfurt am Main to Palermo is $165 (€133) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Frankfurt am Main to Palermo is 33h 55m to travel the 860 miles (1385 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Frankfurt am Main to Palermo leaves at 12:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Frankfurt am Main to Palermo leaves at 11:05 PM.
There are 5 buses a day from Frankfurt am Main to Palermo which require at least one change with FlixBus, Infobus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Frankfurt am Main to Palermo, you can count on FlixBus, Infobus for the best way to get you to Palermo. You can also check all possible bus companies who offer a service between Frankfurt am Main and Palermo and compare the amenities they offer before buying a bus ticket.
When departing from Frankfurt am Main , you have various bus station options to start your journey from including Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36), Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof), Frankfurt am Main, Hauptbahnhof, Darmstadt, Lise-Meitner-Str. / Europaplatz, Darmstadt, Busbahnhof Zweifalltorweg . When arriving in Palermo , you can end your journey in bus stations like Palermo, Via Tommaso Fazello (Terminal Bus), Palermo .Passengers board the bus most frequently from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36), which is located around 10 away from the city centre, and they get off the bus at Palermo, Via Tommaso Fazello (Terminal Bus), located 1 away from the city centre.
A trip to Palermo from Frankfurt am Main is worth doing but not as a day trip with a journey time of 33h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Frankfurt am Main to Palermo is February.
It's helpful to compare your options as there are 3 ways to travel between Frankfurt am Main and Palermo including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from Frankfurt am Main to Palermo for bus company FlixBus, Infobus.
Yes, the following accessibility options are available when taking the bus from Frankfurt am Main to Palermo:
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Palermo are:
- Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
- Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
- Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
- Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
- Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
The best things to do in Palermo include:
- Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
- Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
- Explore the vibrant street art in the Vucciria district
- Take a cooking class to learn how to make traditional Sicilian dishes
- Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
Whether you can cancel your bus ticket from Frankfurt am Main to Palermo depends on the bus companies:
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Infobus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Frankfurt am Main to Palermo.
Yes, the following luggage options are included when booking a bus ticket from Frankfurt am Main to Palermo:
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Frankfurt am Main to Palermo:
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Frankfurt am Main to Palermo. The following conditions apply:
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Frankfurt am Main to Palermo with the following bus company: FlixBus, Infobus
Yes, there are USB plugs on board the bus from Frankfurt am Main to Palermo with the following bus company: FlixBus, Infobus.
Yes, there is Wifi on board the bus from Frankfurt am Main to Palermo with the following bus company: FlixBus, Infobus.
Since both Frankfurt am Main and Palermo are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Frankfurt am Main to Palermo among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Palermo, travelers should be cautious of petty theft, especially pickpocketing in crowded areas like markets and public transport. Scams include overcharging by taxi drivers and vendors, as well as unofficial guides offering overpriced tours. It's advisable to use authorized services and stay vigilant in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Frankfurt am Main to Palermo
Frankfurt am Main
Palermo
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WC
Ticket Officeinformation
Ticket Office Hours
- 00:00-23:59
Distance to city center
10 km
Car connection
Hugo-Eckener-RingWifi
- Free Wi-Fi
Dining
- McDonald's (in the station)
- Hausmann's (in the station).
Taxis
- Available outside the terminal at designated taxi stands.
Accessibility
- Elevators, ramps, assistance
WC
- Available in the station.
Public transit options for Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
- Bus: 61, 62, 77 Train: S8, S9
Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
information
Frankfurt am Main, Hauptbahnhof
information
Most popular bus connections from Frankfurt am Main
More options for your journey from Frankfurt am Main to Palermo
Here are some other resources that might have the information you need
Most popular buses to and from Palermo and Frankfurt am Main
Most popular bus connections to Palermo
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