- Must visit
Galleria Regionale della Sicilia - Palazzo Abatellis
Major Sicilian art museum in a Gothic-Catalan palace, best known for Antonello da Messina and medieval to Renaissance works.
Cheapest price
$271
Average price
$298
Fastest journey
1 d 9 h 55 m
Average duration
1 d 11 h 35 m
Buses per day
7
Distance
1385 km
The best way to find a cheap bus ticket from Frankfurt am Main to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Palermo will cost around $298 if you buy it on the day, but the cheapest tickets can be found for only $271.
It's difficult to get from Frankfurt am Main to Palermo without transferring at least once.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus+
FlixTrain
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Frankfurt am Main to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $95. For those with little time consider booking a flight which can get you there in 2h 59m. The ticket price range depends on the travel mode: a bus costs an average of $95, and a train costs an average of $426.
Distance: 860 miles (1385 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$162 Average price Cheapest | $237 Average price | $426 Average price | $317 Average price (fuel + tolls) |
33h 7m Average total duration 32h 37m Onboard + 30m Additional time* | 5h 59m Average total duration Fastest 2h 59m Onboard + 3h 0m Additional time* | 24h 28m Average total duration 23h 58m Onboard + 30m Additional time* | 22h 1m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frankfurt am Main to Palermo:
A bus is $75 (€62) less than a flight for this route with tickets for a flight from Frankfurt am Main to Palermo costing on average $237 (€195).
A bus is $264 (€217) less than a train for this route with tickets for a train from Frankfurt am Main to Palermo costing on average $426 (€350).
Other travel options to Palermo take longer:
Train takes on average 23h 58m.
Bus takes on average 32h 37m.
Tickets start at around $162 (€133) compared to roughly $317 (€261) in fuel and tolls — a saving of about $155 (€128). The journey takes 32h 37m versus 22h 1m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 11:00AM | Duration 34h15 | Departure days Everyday | Cheapest price $214 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 11:00AM | Duration 33h55 | Departure days Everyday | Cheapest price $214 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 03:15PM | Duration 38h00 | Departure days Everyday | Cheapest price $173 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 03:15PM | Duration 37h35 | Departure days Everyday | Cheapest price $167 |
Operator OneBus | Departure Time 05:20AM | Arrival Time 02:35PM | Duration 33h15 | Departure days Sat | Cheapest price $232 |
Operator FlixBus | Departure Time 08:03PM | Arrival Time 11:00AM | Duration 38h57 | Departure days Everyday | Cheapest price $221 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 11:00AM | Duration 36h15 | Departure days Everyday | Cheapest price $196 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 11:00AM | Duration 35h55 | Departure days Everyday | Cheapest price $203 |
The table below shows live departures for Frankfurt am Main to Palermo buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus+ FlixTrain | 8:03 PM Frankfurt South station | 38h57 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 3 transfers | |
FlixBus · FlixBus · FlixBus | 10:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 36h15 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 35h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
| Friday, July 10 | |||||
FlixBus · FlixBus | 12:45 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 34h15 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 1:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 33h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 38h00 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:40 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 37h35 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frankfurt am Main to Palermo run on average 5 times per day, taking around 32h 37m. Cheap bus tickets for this journey start at $95 (€78) but you can travel from only $24 (€19) by flight.
The earliest bus runs at 00:20, the last at 23:05. The fastest bus covers the 860 miles (1385 km) distance in 33h 55m.
Distance 860 miles (1385 km) |
Average bus duration 32h 37m |
Cheapest ticket price $95 (€78) |
Buses per day 5 |
Fastest bus 33h 55m |
First bus 12:20 AM |
Last bus 11:05 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 49 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Major Sicilian art museum in a Gothic-Catalan palace, best known for Antonello da Messina and medieval to Renaissance works.
One of Italy's oldest archaeological museums, with important Punic, Greek and Roman collections from Sicily and the Mediterranean.
Well-preserved aristocratic residence showing historic interiors, furnishings and decorative arts from Palermo's noble past.
Historic street market area full of energy, local life and vivid scenes, popular with visitors and photographers.
Elegant square famed for its monumental fountain and surrounding historic buildings in the heart of the old city.
Major pedestrian-friendly street linking key historic sights, busy with architecture, shops and constant city life.
Fried rice balls stuffed with ragù, mozzarella, or butter and ham. A Palermo street food icon with a famous local feminine name form.
A traditional sandwich filled with veal spleen and lung, often topped with ricotta or caciocavallo. One of Palermo’s most distinctive historic street foods.
Pasta with sardines, wild fennel, raisins, pine nuts, and anchovies. It reflects the island’s Arab-Norman culinary heritage and sweet-savory style.
Well-regarded restaurant serving polished Sicilian cooking with local ingredients, including pasta, seafood, and traditional Palermo flavors in an elegant casual space.
Famous pastry shop and café celebrated for cannoli, cassata, and other Sicilian sweets. A strong choice for dessert and breakfast in Palermo.
Established restaurant near the historic center, appreciated for refined Sicilian dishes, seasonal produce, and a warm atmosphere blending tradition and creativity.
Generally cheaper than Rome or Milan. Street food and casual dining are affordable, while central hotels cost more in peak season.
Service is often included or minimal. Tipping is not required, but leaving EUR 1-2 at cafes or 5-10% in restaurants for good service is appreciated. Round up taxi fares.
Find answers to the most common questions about traveling from Frankfurt am Main to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main to Palermo buses use the Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Frankfurt am Main and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
Here are some other resources that might have the information you need