Travel Information
Compare bus and train for Syracuse to Palermo
Omio recommends booking the train as it is the most popular option from Syracuse to Palermo among Omio's users. If you are prioritising price, take the train, with an average ticket price of $31 For those with little time, consider booking a bus, which has an average total journey time of 4h 10m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.2kg. Average ticket prices depend on the travel mode: a train costs an average of $31, while a bus costs an average of $35.
Distance: 126 miles (204 km)
Compare train with
Most popular Train | Bus |
|---|---|
$31 Average price Cheapest | $35 Average price |
5h 31m Average total duration 5h 1m Onboard + 30m Additional time* | 4h 10m Average total duration Fastest 3h 40m Onboard + 30m Additional time* |
0.1 - 0.2kg CO2 emissions Lowest | 0.2 - 0.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Syracuse to Palermo:
A train is $4 (€3) less than a bus for this route with tickets for a bus from Syracuse to Palermo costing on average $35 (€29).
Other travel options to Palermo take longer:
Train takes on average 5h 31m.
Travel optionsfrom Syracuse to Palermo
How to get from Syracuse to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Syracuse to Palermo is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus7:15 AM8h00Syracuse, Corso Umberto I3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$181One-way1 transfer
Cheapest
FlixBus · FlixBus7:15 AM8h00Syracuse, Corso Umberto I3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$181One-way1 transfer
Fastest
treno 5384 effettuato con bus PA524 · Regionale Veloce 551111:51 AM4h38Syracuse station4:29 PMPalermo Centrale$241One-way1 transfer
Other options
treno 5380 effettuato con bus PA514 · Regionale Veloce 55035:50 AM4h39Syracuse station10:29 AMPalermo Centrale$241One-way1 transfer
treno 12954 effettuato con bus PA504 · Regionale Veloce 55013:11 AM4h48Syracuse station7:59 AMPalermo Centrale$241One-way1 transfer
treno 5516 effettuato con bus PA530 · Regionale Veloce 55193:35 PM4h54Syracuse station8:29 PMPalermo Centrale$241One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Syracuse to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Syracuse to Palermo.

This is compared to other travel options from Syracuse to Palermo:
A train is $4 (€3) less than a bus for this route with tickets for a bus from Syracuse to Palermo costing on average $35 (€29).
Other travel options to Palermo take longer:
Train takes on average 5h 31m.
- Around 7 trains per day.
- Around 1 buses per day.
However, we recommend checking specific travel dates for your route between Syracuse and Palermo as scheduled services by bus and train can vary by season or day of the week.
- Trains mostly depart from Syracuse station and arrive in Palermo Centrale.
- Buses mostly depart from Syracuse, Corso Umberto I and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Travel with Regionale, Intercity to go to Palermo by train.
- Travel with FlixBus to go to Palermo by bus.
Travelling from Syracuse to Palermo: related information
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