The cheapest and fastest buses from Milan to Palermo
Cheapest price
$101
Average price
$101
Fastest journey
21 h 55 m
Average duration
21 h 55 m
Buses per day
1
Distance
887 km
The best way to find a cheap bus ticket from Milan to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Palermo will cost around $101 if you buy it on the day, but the cheapest tickets can be found for only $101.
Of the 1 buses that leave Milan for Palermo on Thu, Feb 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 05 the direct buses cover the 887 km distance in an average of 21 h 55 m but if you time it right, some buses will get you there in just 21 h 55 m .
On Thu, Feb 05 the slowest buses will take 21 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBusTravel Information
Compare train, bus, flight, and ferry for Milan to Palermo
Omio recommends booking the flight as it is the most popular option from Milan to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from €61. For those with little time consider booking a flight which can get you there in 1h 51m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a ferry costs an average of €61, and a train costs an average of €66.
Distance: 551 miles (887 km)
Compare bus with
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
€89 Average price | €115 Average price | €120 Average price | €68 Average price Cheapest |
20h 37m Average total duration 20h 7m Onboard + 30m Additional time* | 4h 51m Average total duration Fastest 1h 51m Onboard + 3h 0m Additional time* | 15h 30m Average total duration 15h 0m Onboard + 30m Additional time* | 21h 13m Average total duration 20h 13m Onboard + 1h 0m Additional time* |
0.9 - 2.2kg CO2 emissions | 2.7 - 5.3kg CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Milan to Palermo Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 08:50AM | Arrival Time 11:00AM | Duration 26h10 | Departure days Tue | Cheapest price $50 |
Operator FlixBus | Departure Time 10:10AM | Arrival Time 02:25PM | Duration 28h15 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $60 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 11:00AM | Duration 22h30 | Departure days Fri, Sat, Sun | Cheapest price $44 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 11:00AM | Duration 21h55 | Departure days Everyday | Cheapest price $72 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 02:25PM | Duration 23h40 | Departure days Mon, Fri, Sat, Sun | Cheapest price $43 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 02:25PM | Duration 22h55 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $43 |
Live departures
Milan to Palermo bus times
The table below shows live departures for Milan to Palermo buses for today, Wednesday, February 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 12:05 PM Milano, Autostazione Lampugnano | 21h55 | 10:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 0 transfersDirect | |
| Thursday, February 5 | |||||
![]() | 8:00 AM Milan | 21h45 | 5:45 AM Palermo | 0 transfersDirect | |
![]() | 8:10 AM Milan | 28h15 | 12:25 PM Palermo | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Palermo by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Milan to Palermo buses with Omio?
Why book with Omio vs Itabus?
- Compare with other providers: On Omio, you can not only buy tickets for Itabus, but also compare tickets for the likes of FlixBus, Infobus or Autoservizi Salemi to find the best option for your trip from Milan to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Milan to Palermo.
Why book with Omio over Checkmybus or Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus, Infobus or Autoservizi Salemi to find the best option for your trip from Milan to Palermo.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Milan to Palermo.
Journey information
Overview: Bus from Milan to Palermo
Buses from Milan to Palermo run on average 6 times per day, taking around 20h 7m. Cheap bus tickets for this journey start at $42 (€33) but you can travel from only $22 (€17) by flight.
There are 1 buses per day. The earliest bus runs at 00:52, the last at 22:45. The fastest bus covers the 551 miles (887 km) distance in 21h 55m.
Distance 551 miles (887 km) |
Average bus duration 20h 7m |
Cheapest ticket price $42 (€33) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 21h 55m |
First bus 00:52 |
Last bus 22:45 |
Bus providers: Autoservizi Salemi, Itabus, FlixBus, BlaBlaCar, Infobus from Milan to PalermoYou can travel by bus between Milan to Palermo with Autoservizi Salemi, Itabus, FlixBus, BlaBlaCar, Infobus for as low as $22 (€17). When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Infobus
Autoservizi Salemi
BlaBlaCar
Buses from Milan to Palermo
Bus trips to Milan and Palermo have a total duration of about 20 hours, including the passage over the Strait of Messina. Every day there are generally four journeys: two direct journeys and two routes with change, with a departure in the middle of the day and three evening journeys. The vehicles depart from the Bus Station of Lampugnano or the San Donato Bus Station, while the arrival station in Palermo is located in Piazza Cairoli.
Which bus lines operate the Milan-Palermo route?
The company that makes the direct trip is Bus Center, provides two trips a day and provides between services on board toilets and electrical outlets. The connection with gearbox is offered instead by the line Baltour.
How long does the bus journey from Milan to Palermo take?
The direct trip to Milan Palermo operated by Bus Center bus lines lasts from 19 to 22 hours. The change connection proposed by Baltour provides departures from the Bus Station of Lampugnano, with a journey time between 17 hours and 45 minutes and 18 hours and 30 minutes.
How many buses are there Milan-Palermo?
Two direct rides are scheduled each day, departing around 13:45 and 20:45. Coach services that make trips with change leave Milan in the evening with arrival in the next afternoon. A total of at least 25 connections are guaranteed each week.
Where do the buses Milan-Palermo depart from and where do they arrive?
Milan Palermo buses leave from Lampugnano Bus Station, which can be reached by metro, or from Piazzale San Donato Bus Station, which is connected to the city centre by the M3 underground. The terminus is in Palermo in Piazza Cairoli, connected to the rest of the city by several bus lines.
FAQs: Bus from Milan to Palermo
Find answers to the most common questions about traveling from Milan to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
- Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
- Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
- Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
- Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
- Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
- Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
- Explore the vibrant street art in the Vucciria district
- Take a cooking class to learn how to make traditional Sicilian dishes
- Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
- Autoservizi Salemi
- The cancellation policy can vary by ticket class, individual trips, or promotions, so it's best to check the terms during booking.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Autoservizi Salemi
- Two pieces of luggage: one large suitcase for the hold and one smaller backpack for on-board.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Milan to Palermo
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
More options for your journey from Milan to Palermo
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