- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
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The cheapest and fastest buses from Milan to Palermo
Showing times, prices and bookable tickets for Nov 03
- Cheapest price on Nov 03
- $109
- Average ticket price on Nov 03
- $115
- Fastest journey on Nov 03
- 21 h 50 m
- Average journey duration on Nov 03
- 23 h 21 m
- Buses on Nov 03
- 7
- Distance
- 887 km
Cheap tickets
The best way to find a cheap bus ticket from Milan to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Palermo will cost around $115 if you buy it on the day, but the cheapest tickets can be found for only $109.
Fast buses
On Tue, Nov 03, we found 7 buses from Milan to Palermo, including 1 direct services.
On Tue, Nov 03 the direct buses cover the 887 km distance in an average of 23 h 21 m but if you time it right, some buses will get you there in just 21 h 50 m .
On Tue, Nov 03 the slowest buses will take 1 d 1 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus4:40 PM 22h35 Milano, Autostazione Lampugnano 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) $109 1 One-way 1 transfer- FlixBus · FlixBus
5:25 PM 21h50 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) $109 1 One-way 1 transfer - FlixBus
1:05 PM 21h55 Milano, Autostazione Lampugnano 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) $112 1 One-way 0 transfers - FlixBus · FlixBus · FlixBus
10:20 AM 28h55 Milano, Milan Linate Airport 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) $113 1 One-way 2 transfers - FlixBus · FlixBus
8:50 AM 26h10 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) $118 1 One-way 1 transfer
- FlixBus · FlixBus
5:25 PM 21h50 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) $109 1 One-way 1 transfer - FlixBus
1:05 PM 21h55 Milano, Autostazione Lampugnano 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) $112 1 One-way 0 transfers - FlixBus · FlixBus
4:40 PM 22h35 Milano, Autostazione Lampugnano 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) $109 1 One-way 1 transfer - FlixBus · FlixBus
6:30 PM 24h50 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) $124 1 One-way 1 transfer - FlixBus · FlixBus
5:45 PM 25h35 Milano, Autostazione Lampugnano 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) $122 1 One-way 1 transfer
Journey information
Overview: Bus from Milan to Palermo
ItalyItaly
Buses from Milan to Palermo run on average 7 times per day, taking around 22h 7m. Cheap bus tickets for this journey start at $34 but you can travel from only $21 by flight.
There are 1 buses per day. The earliest bus runs at 00:52, the last at 22:45. The fastest bus covers the 551 miles (887 km) distance in 20h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21
Distance 551 miles (887 km) |
Average bus duration 22h 7m |
Cheapest ticket price $34 |
Buses per day 7 |
Direct buses 1 |
Fastest bus 20h 30m |
First bus 12:52 AM |
Last bus 10:45 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sat |
Best time to book 91 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21
Frequently asked questions about your Milan to Palermo trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Milan to Palermo.
Cheap bus tickets from Milan to Palermo can start from as little as $34 when you book in advance. The average bus ticket price for Milan to Palermo is $103 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Milan to Palermo leaves at 12:52 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Milan to Palermo leaves at 10:45 PM.
Yes, there are 1 direct buses a day from Milan to Palermo with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
Milan to Palermo Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 08:50AM | Arrival Time 11:00AM | Duration 26h10 | Departure days Tue | Cheapest price $118 |
Operator Salemi | Departure Time 10:00AM | Arrival Time 07:45AM | Duration 21h45 | Departure days Wed, Fri | Cheapest price $90 |
Operator FlixBus | Departure Time 10:20AM | Arrival Time 03:15PM | Duration 28h55 | Departure days Tue, Wed, Thu, Fri, Sun | Cheapest price $101 |
Operator Salemi | Departure Time 10:45AM | Arrival Time 07:45AM | Duration 21h00 | Departure days Wed, Fri | Cheapest price $90 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 03:15PM | Duration 27h15 | Departure days Sat | Cheapest price $118 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 11:00AM | Duration 22h30 | Departure days Thu, Sat, Sun | Cheapest price $77 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 11:00AM | Duration 22h15 | Departure days Wed, Fri | Cheapest price $92 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 11:00AM | Duration 21h55 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $88 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 03:15PM | Duration 22h35 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $85 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 03:15PM | Duration 21h50 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $83 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 07:20PM | Duration 25h35 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 07:20PM | Duration 24h50 | Departure days Everyday | Cheapest price $91 |
Live departures
Milan to Palermo bus times
The table below shows live departures for Milan to Palermo buses for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 8:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 26h10 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 10:20 AM Milano, Milan Linate Airport | 28h55 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
| FlixBus | 1:05 PM Milano, Autostazione Lampugnano | 21h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 0 transfersDirect | |
| FlixBus · FlixBus | 4:40 PM Milano, Autostazione Lampugnano | 22h35 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
| FlixBus · FlixBus | 5:25 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 21h50 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
| FlixBus · FlixBus | 5:45 PM Milano, Autostazione Lampugnano | 25h35 | 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
| FlixBus · FlixBus | 6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 24h50 | 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Milan to Palermo buses with Omio?
FlixBus as well as Itabus or Salemi offer buses services from Milan to Palermo.
Omio is an official ticket reseller for all your travel options from Milan to Palermo.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus or Salemi to find the best option for your trip from Milan to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Milan to Palermo.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus or Salemi to find the best option for your trip from Milan to Palermo.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Milan to Palermo.
Bus providers: FlixBus, Salemi, Itabus from Milan to PalermoYou can travel by bus between Milan to Palermo with FlixBus, Salemi, Itabus for as low as $21. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
20h 30m
Cheapest FlixBus Price
$34
FlixBus frequency
6 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Itabus
About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Itabus Duration
21h 10m
Cheapest Itabus Price
$43
Itabus frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Salemi
Luggage & cancellation policy
Average Salemi Duration
21h 0m
Cheapest Salemi Price
$90
Salemi frequency
2 a day
Companies, tickets, and onboard amenities between Milan and Palermo
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Milan to Palermo, you can count on FlixBus, Itabus, Salemi for the best way to get you to Palermo. You can also check all possible bus companies who offer a service between Milan and Palermo and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Milan to Palermo:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
Yes, there are bathrooms on board the bus from Milan to Palermo for bus company FlixBus, Itabus.
Whether you can cancel your bus ticket from Milan to Palermo depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Milan to Palermo.
Yes, the following luggage options are included when booking a bus ticket from Milan to Palermo:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Milan to Palermo:
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
Yes, you can bring your pet on the bus from Milan to Palermo. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Milan to Palermo with the following bus company: FlixBus, Itabus
Yes, there are USB plugs on board the bus from Milan to Palermo with the following bus company: FlixBus, Itabus.
Yes, there is Wifi on board the bus from Milan to Palermo with the following bus company: FlixBus, Itabus.
Complete guide to Palermo
Things to do in Palermo
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
- Recommended
Palazzo Mirto
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
- Recommended
Steri Museum
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
- Must visit
Via Vittorio Emanuele
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
- Must visit
Via Maqueda
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
- Recommended
Albergheria
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Arancina
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Pane con la Milza
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta con le Sarde
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
I Pupi
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Osteria Ballarò
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Nni Franco U Vastiddaru
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Euro (€)
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Average meal costs
- Budget
- €8-12 for street food or a simple meal.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale dining.
- Coffee
- €1.50-3 for coffee or cappuccino.
Tipping culture
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Plan your visit to Palermo
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Palermo.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Palermo, travelers should be cautious of petty theft, especially pickpocketing in crowded areas like markets and public transport. Scams include overcharging by taxi drivers and vendors, as well as unofficial guides offering overpriced tours. It's advisable to use authorized services and stay vigilant in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
Buses from Milan to Palermo
Bus trips to Milan and Palermo have a total duration of about 20 hours, including the passage over the Strait of Messina. Every day there are generally four journeys: two direct journeys and two routes with change, with a departure in the middle of the day and three evening journeys. The vehicles depart from the Bus Station of Lampugnano or the San Donato Bus Station, while the arrival station in Palermo is located in Piazza Cairoli.
Which bus lines operate the Milan-Palermo route?
The company that makes the direct trip is Bus Center, provides two trips a day and provides between services on board toilets and electrical outlets. The connection with gearbox is offered instead by the line Baltour.
How long does the bus journey from Milan to Palermo take?
The direct trip to Milan Palermo operated by Bus Center bus lines lasts from 19 to 22 hours. The change connection proposed by Baltour provides departures from the Bus Station of Lampugnano, with a journey time between 17 hours and 45 minutes and 18 hours and 30 minutes.
How many buses are there Milan-Palermo?
Two direct rides are scheduled each day, departing around 13:45 and 20:45. Coach services that make trips with change leave Milan in the evening with arrival in the next afternoon. A total of at least 25 connections are guaranteed each week.
Where do the buses Milan-Palermo depart from and where do they arrive?
Milan Palermo buses leave from Lampugnano Bus Station, which can be reached by metro, or from Piazzale San Donato Bus Station, which is connected to the city centre by the M3 underground. The terminus is in Palermo in Piazza Cairoli, connected to the rest of the city by several bus lines.
FAQs: Bus from Milan to Palermo
Find answers to the most common questions about traveling from Milan to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 4 ways to travel between Milan and Palermo including taking a train, bus, flight, and ferry.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Milan to Palermo
Most Milan to Palermo buses use the Milano, Autostazione Lampugnano to station pair. Use this guide to compare Milan and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Milan
Arrival bus stations in Palermo
Which Milan station do buses to Palermo leave from?
Buses from Milan to Palermo leave from Milano, Autostazione Lampugnano. The station is 3 miles (6 km) from Milan city centre at Via Giulio Natta, 226, 20151 Milano MI, Italy.
Milano, Autostazione LampugnanoVia Giulio Natta, 226, 20151 Milano MI, Italy
City-centre transport
Getting to Milano, Autostazione Lampugnano from Milan city centre
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
BusNm1 · 19m · $3 · every ~2 min
Subway1 · 13m · $3 · every ~18 min
Milano, Autostazione Lampugnano bus station facilities and services
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Milano, Autostazione Lampugnano.
Parking, taxis and toilets
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato)Viale Giuseppe Impastato, Milano, Italy
City-centre transport
Getting to Milano, San Donato - Settore B (Viale Giuseppe Impastato) from Milan city centre
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Bus121, 132 · 18m · $3 · every ~14 min
132 · 20m · $3 · every ~5 min
Milano, San Donato - Settore B (Viale Giuseppe Impastato) bus station facilities and services
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Tickets and information
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Parking, taxis and toilets
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Milano, Aeroporto di Milano Linate
City-centre transport
Getting to Milano, Aeroporto di Milano Linate from Milan city centre
Bus973 · 15m · $3 · every ~5 min
Autostradale 144 · 25m · $2 · every ~3 min
flibco · 25m · $3 · every ~2 min
Subway4 · 12m · $3 · every ~30 min
More options for your journey from Milan to Palermo
Here are some other resources that might have the information you need
Most popular buses to and from Palermo and Milan
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