The cheapest and fastest buses from South Bend, IN to St. Louis, MO
Cheapest price
$111
Average price
$111
Fastest journey
12 h 30 m
Average duration
12 h 30 m
Buses per day
1
Distance
477 km
The best way to find a cheap bus ticket from South Bend, IN to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from South Bend, IN to St. Louis, MO will cost around $111 if you buy it on the day, but the cheapest tickets can be found for only $111.
Of the 1 buses that leave South Bend, IN for St. Louis, MO on Sun, Mar 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct buses cover the 477 km distance in an average of 12 h 30 m but if you time it right, some buses will get you there in just 12 h 30 m .
On Sun, Mar 22 the slowest buses will take 12 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, bus, and flight for South Bend, IN to St. Louis, MO
Omio recommends booking the train as it is the most popular option from South Bend, IN to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $67. For those with little time consider booking a flight which can get you there in 6h 31m. The ticket price range depends on the travel mode: a bus costs an average of $67, and a flight costs an average of $389.
Distance: 296 miles (477 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$95 Average price Cheapest | $128 Average price | $436 Average price |
13h 37m Average total duration 13h 7m Onboard + 30m Additional time* | 7h 39m Average total duration 7h 9m Onboard + 30m Additional time* | 9h 31m Average total duration Fastest 6h 31m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
South Bend, IN to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 08:50AM | Arrival Time 11:20PM | Duration 15h30 | Departure days Mon | Cheapest price $102 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 06:25AM | Duration 12h30 | Departure days Mon | Cheapest price $100 |
Live departures
South Bend, IN to St. Louis, MO bus times
The table below shows live departures for South Bend, IN to St. Louis, MO buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:55 PM South Bend, IN | 12h30 | 12:25 PM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets South Bend, IN to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book South Bend, IN to St. Louis, MO buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from South Bend, IN to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from South Bend, IN to St. Louis, MO.
Journey information
Overview: Bus from South Bend, IN to St. Louis, MO
Buses from South Bend, IN to St. Louis, MO run on average 2 times per day, taking around 13h 7m. Cheap bus tickets for this journey start at $67 (€54) if you book in advance.
The earliest bus runs at 02:30, the last at 23:30. The fastest bus covers the 296 miles (477 km) distance in 12h 30m.
Distance 296 miles (477 km) |
Average bus duration 13h 7m |
Cheapest ticket price $67 (€54) |
Buses per day 2 |
Fastest bus 12h 30m |
First bus 02:30 |
Last bus 23:30 |
Cheapest month Feb |
Cheapest day Wed |
High season Jul - Sep |
Low season Jan - Mar |
Bus providers: Greyhound from South Bend, IN to St. Louis, MOYou can travel by bus between South Bend, IN to St. Louis, MO with Greyhound for as low as $67 (€54). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from South Bend, IN to St. Louis, MO
Find answers to the most common questions about traveling from South Bend, IN to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from South Bend, IN to St. Louis, MO
Most popular bus connections from South Bend, IN
More options for your journey from South Bend, IN to St. Louis, MO
Here are some other resources that might have the information you need
