- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Sep 19
$58
Average ticket price on Sep 19
$58
Fastest journey on Sep 19
12 h 30 m
Average journey duration on Sep 19
12 h 30 m
Buses on Sep 19
1
Distance
477 km
The best way to find a cheap bus ticket from South Bend, IN to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from South Bend, IN to St. Louis, MO will cost around $58 if you buy it on the day, but the cheapest tickets can be found for only $58.
On Sat, Sep 19, we found 1 buses from South Bend, IN to St. Louis, MO, including 1 direct services.
On Sat, Sep 19 the direct buses cover the 477 km distance in an average of 12 h 30 m but if you time it right, some buses will get you there in just 12 h 30 m .
On Sat, Sep 19 the slowest buses will take 12 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from South Bend, IN to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $79 For those with little time, consider booking a flight, which has an average total journey time of 4h 43m. Average ticket prices depend on the travel mode: a bus costs an average of $79, while a flight costs an average of $639.
Distance: 296 miles (477 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$79 Average price Cheapest | $153 Average price | $639 Average price | $83 Average price (fuel + tolls) |
9h 23m Average total duration 8h 53m Onboard + 30m Additional time* | 7h 39m Average total duration 7h 9m Onboard + 30m Additional time* | 4h 43m Average total duration Fastest 2h 43m Onboard + 2h 0m Additional time* | 5h 29m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from South Bend, IN to St. Louis, MO:
A bus is $74 less than a train for this route with tickets for a train from South Bend, IN to St. Louis, MO costing on average $153.
A bus is $560 less than a flight for this route with tickets for a flight from South Bend, IN to St. Louis, MO costing on average $639.
Other travel options to St. Louis, MO take longer:
Train takes on average 7h 9m.
Bus takes on average 8h 53m.
Tickets start at around $79 compared to roughly $83 in fuel and tolls — a saving of about $4. The journey takes 8h 53m versus 5h 29m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 08:50AM | Arrival Time 11:15PM | Duration 15h25 | Departure days Wed | Cheapest price $61 |
Operator Greyhound | Departure Time 12:30PM | Arrival Time 11:15PM | Duration 11h45 | Departure days Mon, Thu, Fri, Sun | Cheapest price $47 |
Operator Greyhound | Departure Time 03:15PM | Arrival Time 07:55AM | Duration 17h40 | Departure days Mon | Cheapest price $54 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 06:20AM | Duration 12h25 | Departure days Wed, Thu, Fri, Sun | Cheapest price $48 |
Operator Barons Bus | Departure Time 08:50PM | Arrival Time 06:25AM | Duration 9h35 | Departure days Tue | Cheapest price $97 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 12:25PM | Duration 12h30 | Departure days Sat | Cheapest price $58 |
The table below shows live departures for South Bend, IN to St. Louis, MO buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 12:30 PM South Bend, South Street Station | 11h45 | 11:15 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
+ FlixBus | 6:55 PM South Bend, South Street Station | 12h25 | 6:20 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from South Bend, IN to St. Louis, MO run on average 2 times per day, taking around 8h 53m. Cheap bus tickets for this journey start at $52 if you book in advance.
The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 296 miles (477 km) distance in 8h 10m.
Distance 296 miles (477 km) |
Average bus duration 8h 53m |
Cheapest ticket price $52 |
Buses per day 2 |
Fastest bus 8h 10m |
First bus 2:00 AM |
Last bus 11:30 PM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from South Bend, IN to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most South Bend, IN to St. Louis, MO buses use the South Bend, South Street Station to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare South Bend, IN and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
South Bend, South Street Station is 1 km from South Bend city centre. Public transport options include:
South Bend, South Street Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at South Bend, South Street Station. ATMs are available at South Bend, South Street Station.
Ticket office support is available at South Bend, South Street Station.
Available at South Bend, South Street Station: Parking, Taxis, WC.
Accessibility facilities are available at South Bend, South Street Station: Wheelchair accessible entrances available.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
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