- Must visit
Paolo Orsi Regional Archaeological Museum
The city's principal archaeological museum, with major collections from prehistoric Sicily, Greek Syracuse, and Roman periods. Essential for understanding the area's history beyond Ortigia.
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The cheapest and fastest buses from Milan to Syracuse
Showing times and prices for May 31
Cheapest price
$120
Average price
$137
Fastest journey
20 h 10 m
Average duration
22 h 35 m
Buses per day
3
Distance
1061 km
Cheap tickets
The best way to find a cheap bus ticket from Milan to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Syracuse will cost around $137 if you buy it on the day, but the cheapest tickets can be found for only $120.
Fast buses
It's difficult to get from Milan to Syracuse without transferring at least once.
FlixBus · FlixBus1:05 PM20h10Milano, Autostazione Lampugnano9:15 AMSyracuse, Corso Umberto I$1201One-way1 transfer- FlixBus · FlixBus9:10 PM23h30Milano, San Donato - Settore B (Viale Giuseppe Impastato)8:40 PMSyracuse, Corso Umberto I$1451One-way1 transfer
- FlixBus · FlixBus8:35 PM24h05Milano, Autostazione Lampugnano8:40 PMSyracuse, Corso Umberto I$1451One-way1 transfer
- FlixBus · FlixBus1:05 PM20h10Milano, Autostazione Lampugnano9:15 AMSyracuse, Corso Umberto I$1201One-way1 transfer
- FlixBus · FlixBus9:10 PM23h30Milano, San Donato - Settore B (Viale Giuseppe Impastato)8:40 PMSyracuse, Corso Umberto I$1451One-way1 transfer
- FlixBus · FlixBus8:35 PM24h05Milano, Autostazione Lampugnano8:40 PMSyracuse, Corso Umberto I$1451One-way1 transfer
Travel Information
Compare bus, train, and flight for Milan to Syracuse
Omio recommends booking the train as it is the most popular option from Milan to Syracuse among Omio's users. If you are prioritising price take the flight with prices starting from $31. For those with little time consider booking a flight which can get you there in 1h 50m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 1.0kg. The ticket price range depends on the travel mode: a flight costs an average of $31, and a train costs an average of $56.
Distance: 659 miles (1061 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$77 Average price | $145 Average price | $48 Average price Cheapest |
21h 20m Average total duration 20h 50m Onboard + 30m Additional time* | 15h 9m Average total duration 14h 39m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* |
1.1 - 2.6kg CO2 emissions | 0.3 - 1.0kg CO2 emissions Lowest | 3.2 - 6.4kg CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Milan to Syracuse is a flight with an average price of $48 (€39).
This is compared to other travel options from Milan to Syracuse:
A flight is $29 (€23) less than a bus for this route with tickets for a bus from Milan to Syracuse costing on average $77 (€62).
A flight is $97 (€78) less than a train for this route with tickets for a train from Milan to Syracuse costing on average $145 (€117).
The fastest way to travel from Milan to Syracuse is by flight with an average journey time of 1h 50m.
Other travel options to Syracuse take longer:
Train takes on average 14h 39m.
Bus takes on average 20h 50m.
It's helpful to compare your options as there are 3 ways to travel between Milan and Syracuse including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Milan to Syracuse among Omio's users.
Milan to Syracuse Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:05AM | Arrival Time 07:15AM | Duration 20h10 | Departure days Mon, Tue, Thu, Fri | Cheapest price $106 |
Operator FlixBus | Departure Time 12:05PM | Arrival Time 08:40AM | Duration 20h35 | Departure days Mon, Tue, Thu, Fri | Cheapest price $42 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 09:15AM | Duration 20h10 | Departure days Wed, Sat, Sun | Cheapest price $83 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 07:40PM | Duration 26h55 | Departure days Fri | Cheapest price $120 |
Operator FlixBus | Departure Time 07:20PM | Arrival Time 06:40PM | Duration 23h20 | Departure days Mon, Tue | Cheapest price $63 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 07:40PM | Duration 23h20 | Departure days Mon, Tue | Cheapest price $69 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 08:40PM | Duration 24h15 | Departure days Wed | Cheapest price $119 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 08:40PM | Duration 24h05 | Departure days Sat, Sun | Cheapest price $132 |
Operator FlixBus | Departure Time 09:05PM | Arrival Time 08:40PM | Duration 23h35 | Departure days Wed | Cheapest price $117 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 08:40PM | Duration 23h30 | Departure days Sat, Sun | Cheapest price $132 |
Live departures
Milan to Syracuse bus times
The table below shows live departures for Milan to Syracuse buses for today, Saturday, May 30. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 1:05 PM Milano, Autostazione Lampugnano | 20h10 | 9:15 AM Syracuse, Corso Umberto I | 1 transfer | |
| FlixBus · FlixBus | 8:35 PM Milano, Autostazione Lampugnano | 24h05 | 8:40 PM Syracuse, Corso Umberto I | 1 transfer | |
| FlixBus · FlixBus | 9:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 23h30 | 8:40 PM Syracuse, Corso Umberto I | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Syracuse by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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May 31
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Why should you book Milan to Syracuse buses with Omio?
FlixBus operates all buses services from Milan to Syracuse.
Omio is an official ticket reseller for all your travel options from Milan to Syracuse.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Milan to Syracuse.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Milan to Syracuse.
Journey information
Overview: Bus from Milan to Syracuse
ItalyItaly
Buses from Milan to Syracuse run on average 3 times per day, taking around 20h 50m. Cheap bus tickets for this journey start at $35 (€28) but you can travel from only $31 (€25) by flight.
The earliest bus runs at 04:38, the last at 21:53. The fastest bus covers the 659 miles (1061 km) distance in 20h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)
Distance 659 miles (1061 km) |
Average bus duration 20h 50m |
Cheapest ticket price $35 (€28) |
Buses per day 3 |
Fastest bus 20h 10m |
First bus 4:38 AM |
Last bus 9:53 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Thu |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)
Bus providers: FlixBus from Milan to SyracuseYou can travel by bus between Milan to Syracuse with FlixBus for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
20h 10m
Cheapest Price
$35 (€28)
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Syracuse
Things to do in Syracuse
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
- Recommended
Bellomo Palace Regional Gallery
An art museum in a medieval palace on Ortigia, known for Sicilian paintings, decorative arts, and Antonello da Messina's celebrated Annunciation.
- Recommended
Papyrus Museum 'Corrado Basile'
A distinctive museum exploring the history of papyrus production in Syracuse, one of the few places in Europe associated with papyrus cultivation and traditional processing.
- Must visit
Ortigia
The historic island heart of Syracuse, filled with Baroque streets, sea views, markets, and major monuments. It is the essential area to explore on foot and the city's top priority for visitors.
- Must visit
Piazza del Duomo
Syracuse's grand central square, framed by the cathedral and elegant Baroque facades. It is one of Sicily's most beautiful piazzas and a key setting for photos and evening walks.
- Recommended
Lungomare di Levante Elio Vittorini
A scenic waterfront promenade along Ortigia's eastern edge, known for sea views, stone terraces, and sunrise photography. Very popular for relaxed walks and social-media-friendly views.
Pasta Alla Siracusana
A local pasta style often made with tomato, garlic, basil, olive oil, and sometimes anchovies or breadcrumbs, reflecting simple Syracuse home cooking.
Pasta Con Le Sarde
Classic Sicilian pasta with sardines, wild fennel, raisins, pine nuts, and breadcrumbs, widely associated with eastern Sicily and commonly enjoyed in Syracuse.
- Gluten-free
Pesce Spada Alla Ghiotta
Swordfish cooked in a rich southern Sicilian sauce with tomato, capers, olives, and onion; a signature seafood dish in coastal Syracuse.
MOON Ortigia
Recognized Ortigia restaurant focused on creative Sicilian cooking with strong vegetarian and gluten-free options in a stylish space.
A Putia Delle Cose Buone
Popular casual spot in Ortigia serving traditional Sicilian plates, sandwiches, and local specialties in a lively atmosphere.
Don Camillo
Established Ortigia restaurant known for refined Sicilian cuisine, seafood, and an elegant setting suited to a special dinner.
Euro
Moderate for Italy: cafes and casual meals are affordable, while Ortigia hotels and seafood dining cost more in peak season.
Average meal costs
- Budget
- EUR 8-15 for pizza, panini, or street food.
- Mid-range
- EUR 20-35 per person at a casual restaurant.
- Fine dining
- EUR 60+ per person at upscale seafood restaurants.
- Coffee
- EUR 1.20-3 for espresso or cappuccino.
Tipping culture
Service is often included or minimal. Rounding up or leaving EUR 1-2 at cafes is common; 5-10% for great restaurant service is appreciated, not required.
MooneyGo
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.50
- Day pass
- EUR 4.00
To the city center
Syracuse, Lungomare Di Levante Elio Vittorini -> Siracusa Railway Station
- Distance
- 2 km
- Travel time
- 25 min
- Urban bus tickets are typically cheaper when bought in advance at tobacco shops or authorised retailers than on board.
- Card payment availability on local buses is not guaranteed, so carry cash or buy tickets in advance using the operator's sales channels.
FAQs: Bus from Milan to Syracuse
Find answers to the most common questions about traveling from Milan to Syracuse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Milan to Syracuse can start from as little as $35 (€28) when you book in advance. The average bus ticket price for Milan to Syracuse is $77 (€62) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Milan to Syracuse is 20h 10m to travel the 659 miles (1061 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Milan to Syracuse leaves at 4:38 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Milan to Syracuse leaves at 9:53 PM.
There are 3 buses a day from Milan to Syracuse which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Milan to Syracuse, you can count on FlixBus for the best way to get you to Syracuse. You can also check all possible bus companies who offer a service between Milan and Syracuse and compare the amenities they offer before buying a bus ticket.
A trip to Syracuse from Milan is worth doing but not as a day trip with a journey time of 20h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Milan to Syracuse is March.
It's helpful to compare your options as there are 3 ways to travel between Milan and Syracuse including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Milan to Syracuse:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Milan to Syracuse for bus company FlixBus.
Some of the most interesting sights to explore in Syracuse are:
- Neapolis Archaeological Park, a historical site featuring the Greek Theatre and Roman Amphitheatre
- Ortigia Island, the historical heart of Syracuse known for its Baroque architecture and charming streets
- Syracuse Cathedral, a stunning cathedral built on the remains of a Greek temple
- Temple of Apollo, one of the oldest Doric temples in Sicily, offering insight into ancient Greek architecture
- Castello Maniace, a 13th-century castle offering panoramic views of the sea and city.
The best things to do in Syracuse include:
- Ear of Dionysius, experience the unique acoustics of this limestone cave
- Aretusa Fountain, admire the legendary freshwater spring surrounded by papyrus plants
- Explore the vibrant local markets, where you can taste and purchase fresh Sicilian produce
- Take a boat tour around Ortigia Island, offering a unique perspective of the city from the water
- Enjoy a traditional Sicilian cooking class, learning to make local dishes with fresh ingredients.
Whether you can cancel your bus ticket from Milan to Syracuse depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Milan to Syracuse.
Yes, the following luggage options are included when booking a bus ticket from Milan to Syracuse:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Milan to Syracuse:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Milan to Syracuse. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Milan to Syracuse with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Milan to Syracuse with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Milan to Syracuse with the following bus company: FlixBus.
Since both Milan and Syracuse are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the train as it is the most popular way to get from Milan to Syracuse among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Syracuse, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas and during events. It's advisable to avoid poorly lit or isolated neighborhoods at night. Common scams include overcharging by unlicensed taxi drivers and fraudulent ticket sellers near popular attractions. Staying alert and using official transportation and ticket services can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Milan to Syracuse
Milan
Syracuse
Milano, Autostazione Lampugnano
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
5 km
Car connection
Via Giulio NattaWifi
- Free Wi-Fi
Dining
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
Taxis
- Available outside the station.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Milano, Autostazione Lampugnano
- Metro: M1 Bus: 68, 78, 80
Milano, San Donato - Settore B (Viale Giuseppe Impastato)
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-22:00
Distance to city center
6 kmCar connection
Viale Giuseppe ImpastatoWifi
- Free Wi-Fi
Dining
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
Taxis
- Available outside the station.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Milano, San Donato - Settore B (Viale Giuseppe Impastato)
- Bus: 121, 132 Metro: M3
Milano, Aeroporto di Milano Linate
information
More options for your journey from Milan to Syracuse
Here are some other resources that might have the information you need
Most popular buses to and from Syracuse and Milan
Most popular bus connections to Syracuse
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