- Must visit
Paolo Orsi Regional Archaeological Museum
Leading archaeology museum with superb Greek and Roman finds, essential for understanding ancient Syracuse and eastern Sicily.
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The cheapest and fastest buses from Milan to Syracuse
Showing times, prices and bookable tickets for Oct 13
Cheapest price on Oct 13
$52
Average ticket price on Oct 13
$55
Fastest journey on Oct 13
20 h 10 m
Average journey duration on Oct 13
22 h 35 m
Buses on Oct 13
3
Distance
1061 km
Cheap tickets
The best way to find a cheap bus ticket from Milan to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Syracuse will cost around $55 if you buy it on the day, but the cheapest tickets can be found for only $52.
Fast buses
It's difficult to get from Milan to Syracuse without transferring at least once.
FlixBus · FlixBus1:05 PM20h10Milano, Autostazione Lampugnano9:15 AMSyracuse, Corso Umberto I$521One-way1 transfer- FlixBus · FlixBus8:35 PM24h05Milano, Autostazione Lampugnano8:40 PMSyracuse, Corso Umberto I$561One-way1 transfer
- FlixBus · FlixBus9:10 PM23h30Milano, San Donato - Settore B (Viale Giuseppe Impastato)8:40 PMSyracuse, Corso Umberto I$561One-way1 transfer
- FlixBus · FlixBus1:05 PM20h10Milano, Autostazione Lampugnano9:15 AMSyracuse, Corso Umberto I$521One-way1 transfer
- FlixBus · FlixBus9:10 PM23h30Milano, San Donato - Settore B (Viale Giuseppe Impastato)8:40 PMSyracuse, Corso Umberto I$561One-way1 transfer
- FlixBus · FlixBus8:35 PM24h05Milano, Autostazione Lampugnano8:40 PMSyracuse, Corso Umberto I$561One-way1 transfer
Journey information
Overview: Bus from Milan to Syracuse
ItalyItaly
Buses from Milan to Syracuse run on average 3 times per day, taking around 20h 58m. Cheap bus tickets for this journey start at $50 but you can travel from only $32 by train.
The earliest bus runs at 04:38, the last at 21:53. The fastest bus covers the 659 miles (1061 km) distance in 19h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $32
Distance 659 miles (1061 km) |
Average bus duration 20h 58m |
Cheapest ticket price $50 |
Buses per day 3 |
Fastest bus 19h 50m |
First bus 4:38 AM |
Last bus 9:53 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Tue |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $32
Milan to Syracuse Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:05PM | Arrival Time 09:15AM | Duration 20h10 | Departure days Everyday | Cheapest price $46 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 08:40PM | Duration 24h15 | Departure days Wed | Cheapest price $66 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 08:40PM | Duration 24h05 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $56 |
Operator FlixBus | Departure Time 09:05PM | Arrival Time 08:40PM | Duration 23h35 | Departure days Wed | Cheapest price $66 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 08:40PM | Duration 23h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $56 |
Live departures
Milan to Syracuse bus times
The table below shows live departures for Milan to Syracuse buses for today, Monday, October 12. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 8:35 PM Milano, Autostazione Lampugnano | 24h05 | 8:40 PM Syracuse, Corso Umberto I | 1 transfer | |
| FlixBus · FlixBus | 9:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 23h30 | 8:40 PM Syracuse, Corso Umberto I | 1 transfer | |
| Tuesday, October 13 | |||||
| FlixBus · FlixBus | 1:05 PM Milano, Autostazione Lampugnano | 20h10 | 9:15 AM Syracuse, Corso Umberto I | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Milan to Syracuse buses with Omio?
FlixBus operates all buses services from Milan to Syracuse.
Omio is an official ticket reseller for all your travel options from Milan to Syracuse.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Milan to Syracuse.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Milan to Syracuse.
Bus providers: FlixBus from Milan to SyracuseYou can travel by bus between Milan to Syracuse with FlixBus for as low as $32. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
19h 50m
Cheapest FlixBus Price
$50
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Syracuse
Things to do in Syracuse
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
- Recommended
Bellomo Palace Regional Gallery
Gallery inside Palazzo Bellomo showing medieval and Baroque art, including Antonello da Messina's celebrated Annunciation.
- Recommended
Archimedes Technopark and Leonardo da Vinci Museum
Interactive science museum focused on Archimedes and Leonardo, engaging for families and visitors curious about inventions.
- Must visit
Ortigia
Syracuse's historic island center, packed with Baroque lanes, seafront walks, ancient ruins, and a vibrant local atmosphere.
- Must visit
Piazza Duomo
Grand limestone square framed by the cathedral and palaces, one of Sicily's most elegant and memorable urban spaces.
- Must visit
Fonte Aretusa
Freshwater spring beside the sea linked to myth, famous for papyrus plants and its central place in Ortigia legends.
- Vegetarian
Pasta alla Norma
Pasta with fresh tomato sauce, fried eggplant, ricotta salata and basil. A classic Sicilian dish tied to nearby Catania and widely loved in Syracuse.
Arancini
Rice balls stuffed with ragù, cheese or butter, then breaded and fried. A staple Sicilian street food eaten across Syracuse.
Pesce Fritto
Small fried fish, often anchovies or whitebait, served simply with lemon. It reflects Syracuse's strong seafood tradition and daily catch.
Don Camillo
Refined Michelin-starred dining on Ortigia with creative Sicilian tasting menus, elegant service and a romantic historic setting.
Caseificio Borderi
Historic market stop famous for sandwiches, charcuterie, cheese and quick Sicilian bites amid the bustling Ortigia food market.
Osteria da Mariano
Well-known Ortigia seafood restaurant serving local fish, pasta and Sicilian classics in a polished but relaxed atmosphere.
Euro (€)
Moderate for Sicily. Dining and hotels are often cheaper than Rome or Milan, while summer stays in Ortigia and tourist dining can raise costs. Local buses are low cost.
Average meal costs
- Budget
- €8-15 for pizza, panini, or casual takeaway.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale seafood or tasting menus.
- Coffee
- €1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or minimal. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. In cafes, small change is enough.
FAQs: Bus from Milan to Syracuse
Find answers to the most common questions about traveling from Milan to Syracuse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Milan to Syracuse can start from as little as $50 when you book in advance. The average bus ticket price for Milan to Syracuse is $126 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Milan to Syracuse is 19h 50m to travel the 659 miles (1061 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Milan to Syracuse leaves at 4:38 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Milan to Syracuse leaves at 9:53 PM.
There are 3 buses a day from Milan to Syracuse which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Milan to Syracuse, you can count on FlixBus for the best way to get you to Syracuse. You can also check all possible bus companies who offer a service between Milan and Syracuse and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 3 ways to travel between Milan and Syracuse including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from Milan to Syracuse for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from Milan to Syracuse:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Milan to Syracuse depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Milan to Syracuse.
Yes, the following luggage options are included when booking a bus ticket from Milan to Syracuse:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Milan to Syracuse:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Milan to Syracuse. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Milan to Syracuse with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Milan to Syracuse with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Milan to Syracuse with the following bus company: FlixBus.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Syracuse, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas and during events. It's advisable to avoid poorly lit or isolated neighborhoods at night. Common scams include overcharging by unlicensed taxi drivers and fraudulent ticket sellers near popular attractions. Staying alert and using official transportation and ticket services can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Milan to Syracuse
Most Milan to Syracuse buses use the Milano, Autostazione Lampugnano to Syracuse, Corso Umberto I station pair. Use this guide to compare Milan and Syracuse bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Milan
Arrival bus stations in Syracuse
Which Milan station do buses to Syracuse leave from?
Buses from Milan to Syracuse leave from Milano, Autostazione Lampugnano. The station is 3 miles (6 km) from Milan city centre at Via Giulio Natta, 226, 20151 Milano MI, Italy.
Milano, Autostazione LampugnanoVia Giulio Natta, 226, 20151 Milano MI, Italy
City-centre transport
Getting to Milano, Autostazione Lampugnano from Milan city centre
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
BusNm1 · 19m · $2 · every ~2 min
Subway1 · 13m · $2 · every ~18 min
Milano, Autostazione Lampugnano bus station facilities and services
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Milano, Autostazione Lampugnano.
Parking, taxis and toilets
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato)Viale Giuseppe Impastato, Milano, Italy
City-centre transport
Getting to Milano, San Donato - Settore B (Viale Giuseppe Impastato) from Milan city centre
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Bus121, 132 · 18m · $2 · every ~14 min
132 · 20m · $2 · every ~5 min
Milano, San Donato - Settore B (Viale Giuseppe Impastato) bus station facilities and services
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Tickets and information
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Parking, taxis and toilets
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
More options for your journey from Milan to Syracuse
Here are some other resources that might have the information you need
Most popular buses to and from Syracuse and Milan
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