- Must visit
Paolo Orsi Regional Archaeological Museum
Leading archaeology museum with superb Greek and Roman finds, essential for understanding ancient Syracuse and eastern Sicily.
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Journey information
Overview: Bus from Brindisi to Syracuse
ItalyItaly
Buses from Brindisi to Syracuse run on average 1 times per day, taking around 11h 52m. Cheap bus tickets for this journey start at $59 if you book in advance.
The earliest bus runs at 05:17, the last at 22:40. The fastest bus covers the 283 miles (456 km) distance in 9h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 283 miles (456 km) |
Average bus duration 11h 52m |
Cheapest ticket price $59 |
Buses per day 1 |
Fastest bus 9h 45m |
First bus 5:17 AM |
Last bus 10:40 PM |
Cheapest Month Jan |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Brindisi to Syracuse trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Brindisi to Syracuse.
Cheap bus tickets from Brindisi to Syracuse can start from as little as $59 when you book in advance. The average bus ticket price for Brindisi to Syracuse is $93 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Brindisi to Syracuse leaves at 5:17 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Brindisi to Syracuse leaves at 10:40 PM.
There are 1 buses a day from Brindisi to Syracuse which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
Brindisi to Syracuse Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:05AM | Arrival Time 06:40PM | Duration 14h35 | Departure days Tue, Thu, Sat, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 05:05AM | Arrival Time 07:40PM | Duration 14h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $43 |
Why should you book Brindisi to Syracuse buses with Omio?
FlixBus operates all buses services from Brindisi to Syracuse.
Omio is an official ticket reseller for all your travel options from Brindisi to Syracuse.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Brindisi to Syracuse.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Brindisi to Syracuse.
Bus providers: FlixBus from Brindisi to SyracuseYou can travel by bus between Brindisi to Syracuse with FlixBus for as low as $59. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 45m
Cheapest FlixBus Price
$59
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Companies, tickets, and onboard amenities between Brindisi and Syracuse
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Brindisi to Syracuse, you can count on FlixBus for the best way to get you to Syracuse. You can also check all possible bus companies who offer a service between Brindisi and Syracuse and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Brindisi to Syracuse:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Brindisi to Syracuse for bus company FlixBus.
Whether you can cancel your bus ticket from Brindisi to Syracuse depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Brindisi to Syracuse.
Yes, the following luggage options are included when booking a bus ticket from Brindisi to Syracuse:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Brindisi to Syracuse:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Brindisi to Syracuse. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Brindisi to Syracuse with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Brindisi to Syracuse with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Brindisi to Syracuse with the following bus company: FlixBus.
Complete guide to Syracuse
Things to do in Syracuse
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
- Recommended
Bellomo Palace Regional Gallery
Gallery inside Palazzo Bellomo showing medieval and Baroque art, including Antonello da Messina's celebrated Annunciation.
- Recommended
Archimedes Technopark and Leonardo da Vinci Museum
Interactive science museum focused on Archimedes and Leonardo, engaging for families and visitors curious about inventions.
- Must visit
Ortigia
Syracuse's historic island center, packed with Baroque lanes, seafront walks, ancient ruins, and a vibrant local atmosphere.
- Must visit
Piazza Duomo
Grand limestone square framed by the cathedral and palaces, one of Sicily's most elegant and memorable urban spaces.
- Must visit
Fonte Aretusa
Freshwater spring beside the sea linked to myth, famous for papyrus plants and its central place in Ortigia legends.
- Vegetarian
Pasta alla Norma
Pasta with fresh tomato sauce, fried eggplant, ricotta salata and basil. A classic Sicilian dish tied to nearby Catania and widely loved in Syracuse.
Arancini
Rice balls stuffed with ragù, cheese or butter, then breaded and fried. A staple Sicilian street food eaten across Syracuse.
Pesce Fritto
Small fried fish, often anchovies or whitebait, served simply with lemon. It reflects Syracuse's strong seafood tradition and daily catch.
Don Camillo
Refined Michelin-starred dining on Ortigia with creative Sicilian tasting menus, elegant service and a romantic historic setting.
Caseificio Borderi
Historic market stop famous for sandwiches, charcuterie, cheese and quick Sicilian bites amid the bustling Ortigia food market.
Osteria da Mariano
Well-known Ortigia seafood restaurant serving local fish, pasta and Sicilian classics in a polished but relaxed atmosphere.
Euro (€)
Moderate for Sicily. Dining and hotels are often cheaper than Rome or Milan, while summer stays in Ortigia and tourist dining can raise costs. Local buses are low cost.
Average meal costs
- Budget
- €8-15 for pizza, panini, or casual takeaway.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale seafood or tasting menus.
- Coffee
- €1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or minimal. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. In cafes, small change is enough.
Plan your visit to Syracuse
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Syracuse.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Syracuse, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas and during events. It's advisable to avoid poorly lit or isolated neighborhoods at night. Common scams include overcharging by unlicensed taxi drivers and fraudulent ticket sellers near popular attractions. Staying alert and using official transportation and ticket services can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Brindisi to Syracuse
Find answers to the most common questions about traveling from Brindisi to Syracuse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 2 ways to travel between Brindisi and Syracuse including taking a bus and train.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Brindisi to Syracuse
Most Brindisi to Syracuse buses use the Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) to station pair. Use this guide to compare Brindisi and Syracuse bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Brindisi
Arrival bus stations in Syracuse
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)Brindisi Falcone Professional Institute, Via Giuseppe Maria Galanti 8, 72100
More options for your journey from Brindisi to Syracuse
Here are some other resources that might have the information you need
Most popular buses to and from Syracuse and Brindisi
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