The cheapest and fastest buses from Brindisi to Syracuse
Cheapest price
$47
Average price
$47
Fastest journey
14 h 25 m
Average duration
14 h 25 m
Buses per day
1
Distance
456 km
The best way to find a cheap bus ticket from Brindisi to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Syracuse will cost around $47 if you buy it on the day, but the cheapest tickets can be found for only $47.
Of the 1 buses that leave Brindisi for Syracuse on Sat, Mar 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 21 the direct buses cover the 456 km distance in an average of 14 h 25 m but if you time it right, some buses will get you there in just 14 h 25 m .
On Sat, Mar 21 the slowest buses will take 14 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train and bus for Brindisi to Syracuse
Omio recommends booking the train as it is the most popular option from Brindisi to Syracuse among Omio's users. If you are prioritising price take the train with prices starting from $37. For those with little time consider booking a bus which can get you there in 14h 25m. The ticket price range depends on the travel mode: a train costs an average of $37, and a bus costs an average of $34.
Distance: 283 miles (456 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$76 Average price | $61 Average price Cheapest |
14h 55m Average total duration Fastest 14h 25m Onboard + 30m Additional time* | 15h 15m Average total duration 14h 45m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Brindisi to Syracuse bus times
The table below shows live departures for Brindisi to Syracuse buses for tomorrow, Friday, March 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:15 AM Brindisi | 14h25 | 7:40 PM Syracuse | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brindisi to Syracuse by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Journey information
Overview: Bus from Brindisi to Syracuse
Buses from Brindisi to Syracuse run on average 1 times per day, taking around 14h 25m. Cheap bus tickets for this journey start at $34 (€28) if you book in advance.
The earliest bus runs at 06:05, the last at 22:40. The fastest bus covers the 283 miles (456 km) distance in 14h 25m.
Distance 283 miles (456 km) |
Average bus duration 14h 25m |
Cheapest ticket price $34 (€28) |
Buses per day 1 |
Fastest bus 14h 25m |
First bus 06:05 |
Last bus 22:40 |
Cheapest month Jan |
Cheapest day Mon |
High season Apr - Jun |
Low season Oct - Dec |
Busiest day Wed |
Least busy day Wed |
Best day to book ahead 14 days |
FAQs: Bus from Brindisi to Syracuse
Find answers to the most common questions about traveling from Brindisi to Syracuse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

- Neapolis Archaeological Park, a historical site featuring the Greek Theatre and Roman Amphitheatre
- Ortigia Island, the historical heart of Syracuse known for its Baroque architecture and charming streets
- Syracuse Cathedral, a stunning cathedral built on the remains of a Greek temple
- Temple of Apollo, one of the oldest Doric temples in Sicily, offering insight into ancient Greek architecture
- Castello Maniace, a 13th-century castle offering panoramic views of the sea and city.
- Ear of Dionysius, experience the unique acoustics of this limestone cave
- Aretusa Fountain, admire the legendary freshwater spring surrounded by papyrus plants
- Explore the vibrant local markets, where you can taste and purchase fresh Sicilian produce
- Take a boat tour around Ortigia Island, offering a unique perspective of the city from the water
- Enjoy a traditional Sicilian cooking class, learning to make local dishes with fresh ingredients.
popular bus stations
Popular bus stations from Brindisi to Syracuse
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