The cheapest and fastest buses from Brindisi to Syracuse
Cheapest price
$87
Average price
$87
Fastest journey
10 h 55 m
Average duration
10 h 55 m
Buses per day
1
Distance
456 km
The best way to find a cheap bus ticket from Brindisi to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Syracuse will cost around $87 if you buy it on the day, but the cheapest tickets can be found for only $87.
Of the 1 buses that leave Brindisi for Syracuse on Sun, Dec 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 456 km distance in an average of 10 h 55 m but if you time it right, some buses will get you there in just 10 h 55 m .
On Sun, Dec 21 the slowest buses will take 10 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and train for Brindisi to Syracuse
Omio recommends booking the train as it is the most popular option from Brindisi to Syracuse among Omio's users. If you are prioritising price take the train with prices starting from €31. For those with little time consider booking a bus which can get you there in 12h 27m. The ticket price range depends on the travel mode: a train costs an average of €31, and a bus costs an average of €39.
Distance: 283 miles (456 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€67 Average price | €60 Average price Cheapest |
12h 57m Average total duration Fastest 12h 27m Onboard + 30m Additional time* | 15h 48m Average total duration 15h 18m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Brindisi to Syracuse by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Journey information
Overview: Bus from Brindisi to Syracuse
Buses from Brindisi to Syracuse run on average 1 times per day, taking around 12h 27m. Cheap bus tickets for this journey start at $49 (€39) but you can travel from only $38 (€31) by train.
The earliest bus runs at 06:15, the last at 22:40. The fastest bus covers the 283 miles (456 km) distance in 10h 55m.
Distance 283 miles (456 km) |
Average bus duration 12h 27m |
Cheapest ticket price $49 (€39) |
Buses per day 1 |
Fastest bus 10h 55m |
First bus 06:15 |
Last bus 22:40 |
FAQs: Bus from Brindisi to Syracuse
Find answers to the most common questions about traveling from Brindisi to Syracuse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Neapolis Archaeological Park, a historical site featuring the Greek Theatre and Roman Amphitheatre
- Ortigia Island, the historical heart of Syracuse known for its Baroque architecture and charming streets
- Syracuse Cathedral, a stunning cathedral built on the remains of a Greek temple
- Temple of Apollo, one of the oldest Doric temples in Sicily, offering insight into ancient Greek architecture
- Castello Maniace, a 13th-century castle offering panoramic views of the sea and city.
- Ear of Dionysius, experience the unique acoustics of this limestone cave
- Aretusa Fountain, admire the legendary freshwater spring surrounded by papyrus plants
- Explore the vibrant local markets, where you can taste and purchase fresh Sicilian produce
- Take a boat tour around Ortigia Island, offering a unique perspective of the city from the water
- Enjoy a traditional Sicilian cooking class, learning to make local dishes with fresh ingredients.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Brindisi to Syracuse, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Brindisi to Syracuse
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