- Must visit
Paolo Orsi Regional Archaeological Museum
The city's principal archaeological museum, with major collections from prehistoric Sicily, Greek Syracuse, and Roman periods. Essential for understanding the area's history beyond Ortigia.
Cheapest price
$38
Average price
$43
Fastest journey
15 h 40 m
Average duration
16 h 45 m
Buses per day
4
Distance
817 km
The best way to find a cheap bus ticket from Florence to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence to Syracuse will cost around $43 if you buy it on the day, but the cheapest tickets can be found for only $38.
Of the 4 buses that leave Florence for Syracuse on Sun, May 31, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, May 31 the direct buses cover the 817 km distance in an average of 16 h 45 m but if you time it right, some buses will get you there in just 15 h 40 m .
On Sun, May 31 the slowest buses will take 19 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Omio recommends booking the train as it is the most popular option from Florence to Syracuse among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 2h 3m. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $161.
Distance: 507 miles (817 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$57 Average price Cheapest | $123 Average price | $161 Average price |
15h 34m Average total duration 15h 4m Onboard + 30m Additional time* | 14h 10m Average total duration 13h 40m Onboard + 30m Additional time* | 5h 3m Average total duration Fastest 2h 3m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence to Syracuse:
A bus is $66 (€53) less than a train for this route with tickets for a train from Florence to Syracuse costing on average $123 (€99).
A bus is $104 (€84) less than a flight for this route with tickets for a flight from Florence to Syracuse costing on average $161 (€130).
Other travel options to Syracuse take longer:
Train takes on average 13h 40m.
Bus takes on average 15h 4m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 07:40PM | Duration 19h35 | Departure days Sun | Cheapest price $46 |
Operator FlixBus | Departure Time 12:40AM | Arrival Time 08:40PM | Duration 20h00 | Departure days Wed | Cheapest price $71 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 08:40PM | Duration 19h35 | Departure days Wed | Cheapest price $67 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 07:55AM | Duration 15h55 | Departure days Tue, Thu, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 08:35AM | Duration 15h50 | Departure days Sun | Cheapest price $46 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 08:40AM | Duration 15h40 | Departure days Mon, Tue, Thu, Fri, Sun | Cheapest price $38 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 09:15AM | Duration 15h15 | Departure days Wed, Sat | Cheapest price $67 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 06:40PM | Duration 21h30 | Departure days Mon, Thu, Fri | Cheapest price $80 |
Operator FlixBus | Departure Time 10:10PM | Arrival Time 07:40PM | Duration 21h30 | Departure days Mon, Thu, Fri | Cheapest price $34 |
Operator FlixBus | Departure Time 11:10PM | Arrival Time 08:40PM | Duration 21h30 | Departure days Sat | Cheapest price $106 |
The table below shows live departures for Florence to Syracuse buses for today, Saturday, May 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 6:00 PM Scandicci, Villa Costanza (Florence) | 15h15 | 9:15 AM Syracuse, Corso Umberto I | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:10 PM Scandicci, Villa Costanza (Florence) | 21h30 | 8:40 PM Syracuse, Corso Umberto I | 2 transfers | |
| Sunday, May 31 | |||||
![]() | 12:05 AM Florence | 19h35 | 7:40 PM Syracuse | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Florence to Syracuse run on average 3 times per day, taking around 15h 4m. Cheap bus tickets for this journey start at $32 (€26) if you book in advance.
The earliest bus runs at 00:40, the last at 23:10. The fastest bus covers the 507 miles (817 km) distance in 15h 15m.
Distance 507 miles (817 km) |
Average bus duration 15h 4m |
Cheapest ticket price $32 (€26) |
Buses per day 3 |
Fastest bus 15h 15m |
First bus 12:40 AM |
Last bus 11:10 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 21 days |
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
The city's principal archaeological museum, with major collections from prehistoric Sicily, Greek Syracuse, and Roman periods. Essential for understanding the area's history beyond Ortigia.
An art museum in a medieval palace on Ortigia, known for Sicilian paintings, decorative arts, and Antonello da Messina's celebrated Annunciation.
A distinctive museum exploring the history of papyrus production in Syracuse, one of the few places in Europe associated with papyrus cultivation and traditional processing.
The historic island heart of Syracuse, filled with Baroque streets, sea views, markets, and major monuments. It is the essential area to explore on foot and the city's top priority for visitors.
Syracuse's grand central square, framed by the cathedral and elegant Baroque facades. It is one of Sicily's most beautiful piazzas and a key setting for photos and evening walks.
A scenic waterfront promenade along Ortigia's eastern edge, known for sea views, stone terraces, and sunrise photography. Very popular for relaxed walks and social-media-friendly views.
A local pasta style often made with tomato, garlic, basil, olive oil, and sometimes anchovies or breadcrumbs, reflecting simple Syracuse home cooking.
Classic Sicilian pasta with sardines, wild fennel, raisins, pine nuts, and breadcrumbs, widely associated with eastern Sicily and commonly enjoyed in Syracuse.
Swordfish cooked in a rich southern Sicilian sauce with tomato, capers, olives, and onion; a signature seafood dish in coastal Syracuse.
Recognized Ortigia restaurant focused on creative Sicilian cooking with strong vegetarian and gluten-free options in a stylish space.
Popular casual spot in Ortigia serving traditional Sicilian plates, sandwiches, and local specialties in a lively atmosphere.
Established Ortigia restaurant known for refined Sicilian cuisine, seafood, and an elegant setting suited to a special dinner.
Moderate for Italy: cafes and casual meals are affordable, while Ortigia hotels and seafood dining cost more in peak season.
Service is often included or minimal. Rounding up or leaving EUR 1-2 at cafes is common; 5-10% for great restaurant service is appreciated, not required.
Official public transport app
Syracuse, Lungomare Di Levante Elio Vittorini -> Siracusa Railway Station
Find answers to the most common questions about traveling from Florence to Syracuse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need