Roanoke, VA to St. Louis, MO bus

Thu, May 07
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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The cheapest and fastest buses from Roanoke, VA to St. Louis, MO

Showing times and prices for May 07

Cheapest price

$180

Average price

$180

Fastest journey

20 h 20 m

Average duration

20 h 20 m

Buses per day

1

Distance

911 km

Cheap tickets

The best way to find a cheap bus ticket from Roanoke, VA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Roanoke, VA to St. Louis, MO will cost around $180 if you buy it on the day, but the cheapest tickets can be found for only $180.

Fast buses

It's difficult to get from Roanoke, VA to St. Louis, MO without transferring at least once.

  • Greyhound USA
    12:50 PM20h20
    Roanoke, VA
    9:10 AMSt. Louis, MO
    $1801One-way
    1 transfer

Live departures

Roanoke, VA to St. Louis, MO bus times

The table below shows live departures for Roanoke, VA to St. Louis, MO buses for today, Wednesday, May 6. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound12:50 PM Roanoke, VA
20h20
9:10 AM St. Louis, MO1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Roanoke, VA to St. Louis, MO by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
May 07
Fri
May 08
Sat
May 09
Sun
May 10
Mon
May 11
Tue
May 12
Wed
May 13

Journey information

Overview: Bus from Roanoke, VA to St. Louis, MO

USAUSA
USAUSA
Icon of bus

Take a bus from Roanoke, VA to St. Louis, MO and enjoy the approximately 566 miles (911 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 02:00, the last at 23:30.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $334 (€267)
Distance
566 miles (911 km)
Buses per day
1
First bus
2:00 AM
Last bus
11:30 PM
Cheapest Month
Sep
Cheapest Day
Mon
High Season
Jul - Sep
Low Season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $334 (€267)

FAQs: Bus from Roanoke, VA to St. Louis, MO

Find answers to the most common questions about traveling from Roanoke, VA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Roanoke, VA to St. Louis, MO leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Roanoke, VA to St. Louis, MO leaves at 11:30 PM.
The cheapest month for a bus from Roanoke, VA to St. Louis, MO is September.
It's helpful to compare your options as there are 2 ways to travel between Roanoke, VA and St. Louis, MO including taking a train and bus.
No, there are no bathrooms on board the bus from Roanoke, VA to St. Louis, MO.
No, the bus from Roanoke, VA to St. Louis, MO has no accessibility options.
No, bikes are not allowed on board the bus from Roanoke, VA to St. Louis, MO.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Roanoke, VA to St. Louis, MO.
No, luggage for the bus from Roanoke, VA to St. Louis, MO needs to be booked in addition.
No, there are no additional luggage options for the bus from Roanoke, VA to St. Louis, MO.
Unfortunately, pets are not allowed on the bus from Roanoke, VA to St. Louis, MO.
No, there are no USB plugs on board the bus from Roanoke, VA to St. Louis, MO.
No, there is no WiFi on board the bus from Roanoke, VA to St. Louis, MO.
Since neither Roanoke, VA nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Roanoke, VA to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Roanoke, VA to St. Louis, MO

Roanoke
St. Louis
The major bus station for departures in Roanoke is Roanoke, Third Street Station. Find all the information you need to know about services, amenities and connections at Roanoke, Third Street Station for your trip from Roanoke to St. Louis.
Roanoke, Third Street Station
information

More options for your journey from Roanoke, VA to St. Louis, MO

Here are some other resources that might have the information you need

Tickets and more information for coaches to Roanoke, VA
Tickets and more information for coaches to St. Louis, MO

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