- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Roanoke, VA to St. Louis, MO
Showing times and prices for Aug 05
Cheapest price
$113
Average price
$113
Fastest journey
1 d 3 h 20 m
Average duration
1 d 3 h 45 m
Buses per day
2
Distance
911 km
Cheap tickets
The best way to find a cheap bus ticket from Roanoke, VA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Roanoke, VA to St. Louis, MO will cost around $113 if you buy it on the day, but the cheapest tickets can be found for only $113.
Fast buses
It's difficult to get from Roanoke, VA to St. Louis, MO without transferring at least 2 times.
+
FlixBus+ · 12:50 PM27h20Roanoke, Third Street Station, VA3:10 PMSt. Louis, S 15th St (Civic center)$1131One-way3 transfers- · · 4:35 AM28h10Roanoke, Third Street Station, VA7:45 AMSt. Louis, S 15th St (Civic center)$1131One-way2 transfers
- +FlixBus+ · 12:50 PM27h20Roanoke, Third Street Station, VA3:10 PMSt. Louis, S 15th St (Civic center)$1131One-way3 transfers
- · · 4:35 AM28h10Roanoke, Third Street Station, VA7:45 AMSt. Louis, S 15th St (Civic center)$1131One-way2 transfers
Travel Information
Compare train and bus for Roanoke, VA to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Roanoke, VA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $206. For those with little time consider booking a bus which can get you there in 27h 30m. The ticket price range depends on the travel mode: a bus costs an average of $206, and a train costs an average of $670.
Distance: 566 miles (911 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$206 Average price Cheapest | $670 Average price | $137 Average price (fuel + tolls) |
28h 0m Average total duration Fastest 27h 30m Onboard + 30m Additional time* | 36h 34m Average total duration 36h 4m Onboard + 30m Additional time* | 10h 9m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Roanoke, VA to St. Louis, MO is a bus with an average price of $206.
This is compared to other travel options from Roanoke, VA to St. Louis, MO:
A bus is $464 less than a train for this route with tickets for a train from Roanoke, VA to St. Louis, MO costing on average $670.
The fastest way to travel from Roanoke, VA to St. Louis, MO is by bus with an average journey time of 27h 30m.
Other travel options to St. Louis, MO take longer:
Train takes on average 36h 4m.
It's helpful to compare your options as there are 2 ways to travel between Roanoke, VA and St. Louis, MO including taking a train and bus.
We recommend using the train as it is the most popular way to get from Roanoke, VA to St. Louis, MO among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Roanoke, VA to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:35AM | Arrival Time 07:45AM | Duration 28h10 | Departure days Mon, Wed, Sun | Cheapest price $107 |
Operator Greyhound USA | Departure Time 12:50PM | Arrival Time 09:10AM | Duration 20h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $97 |
Live departures
Roanoke, VA to St. Louis, MO bus times
The table below shows live departures for Roanoke, VA to St. Louis, MO buses for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · | 4:35 AM Roanoke, Third Street Station, VA | 28h10 | 7:45 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
| +FlixBus+ · | 12:50 PM Roanoke, Third Street Station, VA | 27h20 | 3:10 PM St. Louis, S 15th St (Civic center) | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Roanoke, VA to St. Louis, MO by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Wed
Aug 05
Aug 05
Thu
Aug 06
Aug 06
Fri
Aug 07
Aug 07
Sat
Aug 08
Aug 08
Sun
Aug 09
Aug 09
Mon
Aug 10
Aug 10
Tue
Aug 11
Aug 11
Why should you book Roanoke, VA to St. Louis, MO buses with Omio?
Greyhound operates all buses services from Roanoke, VA to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Roanoke, VA to St. Louis, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from Roanoke, VA to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Roanoke, VA to St. Louis, MO.
Journey information
Overview: Bus from Roanoke, VA to St. Louis, MO
USAUSA
Buses from Roanoke, VA to St. Louis, MO run on average 1 times per day, taking around 27h 30m. Cheap bus tickets for this journey start at $206 if you book in advance.
The earliest bus runs at 01:55, the last at 23:45. The fastest bus covers the 566 miles (911 km) distance in 27h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 566 miles (911 km) |
Average bus duration 27h 30m |
Cheapest ticket price $206 |
Buses per day 1 |
Fastest bus 27h 30m |
First bus 1:55 AM |
Last bus 11:45 PM |
Cheapest Month Sep |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Roanoke, VA to St. Louis, MOYou can travel by bus between Roanoke, VA to St. Louis, MO with Greyhound for as low as $206. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
27h 30m
Cheapest Price
$206
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: Bus from Roanoke, VA to St. Louis, MO
Find answers to the most common questions about traveling from Roanoke, VA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Roanoke, VA to St. Louis, MO can start from as little as $206 when you book in advance. The average bus ticket price for Roanoke, VA to St. Louis, MO is $206 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Roanoke, VA to St. Louis, MO is 27h 30m to travel the 566 miles (911 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Roanoke, VA to St. Louis, MO leaves at 1:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Roanoke, VA to St. Louis, MO leaves at 11:45 PM.
There are 1 buses a day from Roanoke, VA to St. Louis, MO which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Roanoke, VA to St. Louis, MO, you can count on Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Roanoke, VA and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Roanoke, Third Street Station, VA, which is located around away from the city centre, and they get off the bus at St. Louis, S 15th St (Civic center), located 0 away from the city centre.
A trip to St. Louis, MO from Roanoke, VA is worth doing but not as a day trip with a journey time of 27h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Roanoke, VA to St. Louis, MO is September.
It's helpful to compare your options as there are 2 ways to travel between Roanoke, VA and St. Louis, MO including taking a train and bus.
Yes, there are bathrooms on board the bus from Roanoke, VA to St. Louis, MO for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Roanoke, VA to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Roanoke, VA to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Roanoke, VA to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Roanoke, VA to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Roanoke, VA to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Roanoke, VA to St. Louis, MO.
You can reserve your seat on the bus from Roanoke, VA to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Roanoke, VA to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Roanoke, VA to St. Louis, MO with the following bus company: Greyhound.
Since neither Roanoke, VA nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Roanoke, VA to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Roanoke, VA to St. Louis, MO
Most Roanoke, VA to St. Louis, MO buses use the Roanoke, Third Street Station to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Roanoke, VA and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Roanoke
Arrival bus stations in St. Louis
Which Roanoke, VA station do buses to St. Louis, MO leave from?
Buses from Roanoke, VA to St. Louis, MO leave from Roanoke, Third Street Station. The station is from Roanoke, VA city centre at Third Street Station, Roanoke, VA 24016, USA.
Roanoke, Third Street StationThird Street Station, Roanoke, VA 24016, USA
City-centre transport
Getting to Roanoke, Third Street Station from Roanoke city centre
TRUE
Roanoke, Third Street Station bus station facilities and services
Roanoke, Third Street Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Roanoke, Third Street Station. ATMs are available at Roanoke, Third Street Station.
Tickets and information
Ticket office support is available at Roanoke, Third Street Station.
Parking, taxis and toilets
Available at Roanoke, Third Street Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roanoke, Third Street Station: Station is wheelchair accessible.
Which St. Louis, MO station do buses from Roanoke, VA arrive at?
Buses from Roanoke, VA to St. Louis, MO arrive at St. Louis, S 15th St (Civic center). St. Louis, S 15th St (Civic center) is 0 miles (1 km) from St. Louis, MO city centre.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Most popular bus connections from Roanoke, VA
More options for your journey from Roanoke, VA to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Roanoke, VA
Most popular bus connections to St. Louis, MO
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
