- Must visit
Museo Archeologico Provinciale Francesco Ribezzo
Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.
The best way to find a cheap train ticket from Pisa to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brindisi will cost around $126 if you buy it on the day, but the cheapest tickets can be found for only $84.
It's difficult to get from Pisa to Brindisi without transferring at least once.
Regionale 18286 · Regionale 94455+
Intercity 609
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Regionale Veloce 4014 · Regionale 17816+
Intercity 607
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InterCityNotte 899+
Intercity 701+
Regionale 19979
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Regionale 2294+
Intercity 607
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Regionale 18260+
FRECCIAROSSA 9511
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Regionale 18260+
FRECCIAROSSA 9511
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Intercity 505+
FRECCIAROSSA 8315
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FRECCIABIANCA 8613+
FRECCIAROSSA 8323
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Regionale Veloce 4018+
FRECCIAROSSA 9490 · FRECCIAROSSA 9805
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Regionale Veloce 4034+
FRECCIAROSSA 9420 · FRECCIAROSSA 8813
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Trains from Pisa to Brindisi run on average 19 times per day, taking around 10h 9m. Cheap train tickets for this journey start at $12 if you book in advance.
The earliest train runs at 00:01, the last at 23:30. The fastest train covers the 441 miles (710 km) distance in 7h 45m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Pisa to Brindisi.
The table below shows live departures for Pisa to Brindisi trains for today, Tuesday, November 3. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FRECCIAROSSA 8323+ FRECCIABIANCA 8613 | 2:07 PM Pisa Centrale | 9h13 | 11:20 PM Brindisi station | 1 transfer | |
Regionale Veloce 4038+ FRECCIAROSSA 9421 · FRECCIAROSSA 8323 | 2:32 PM Pisa Centrale | 8h48 | 11:20 PM Brindisi station | 2 transfers | |
| Wednesday, November 4 | |||||
InterCityNotte 899+ Intercity 701+ Regionale 19979 | 2:21 AM Pisa Centrale | 12h45 | 3:06 PM Brindisi station | 2 transfers | |
Regionale 2294+ Intercity 607 | 6:00 AM Pisa Centrale | 14h12 | 8:12 PM Brindisi station | 1 transfer | |
Regionale 18260+ FRECCIAROSSA 9511 | 6:29 AM Pisa Centrale | 8h59 | 3:28 PM Brindisi station | 1 transfer | |
Intercity 662 · Intercity 609 | 6:42 AM Pisa Centrale | 15h41 | 10:23 PM Brindisi station | 1 transfer | |
Regionale Veloce 4014 · Regionale 17816+ Intercity 607 | 7:38 AM Pisa Centrale | 12h34 | 8:12 PM Brindisi station | 2 transfers | |
Regionale Veloce 4018+ FRECCIAROSSA 9490 · FRECCIAROSSA 9805 | 9:09 AM Pisa Centrale | 9h15 | 6:24 PM Brindisi station | 2 transfers | |
FRECCIAROSSA 8551 · FRECCIAROSSA 8311+ Regionale Veloce 4427 | 9:15 AM Pisa Centrale | 9h59 | 7:14 PM Brindisi station | 2 transfers | |
Regionale Veloce 4020+ FRECCIAROSSA 9520+ Intercity 607 | 9:32 AM Pisa Centrale | 10h40 | 8:12 PM Brindisi station | 2 transfers | |
Regionale 18286 · Regionale 94455+ Intercity 609 | 10:01 AM Pisa Centrale | 12h22 | 10:23 PM Brindisi station | 2 transfers | |
Intercity 505+ FRECCIAROSSA 8315 | 11:11 AM Pisa Centrale | 9h09 | 8:20 PM Brindisi station | 1 transfer | |
Regionale Veloce 4034+ FRECCIAROSSA 9420 · FRECCIAROSSA 8813 | 1:09 PM Pisa Centrale | 9h23 | 10:32 PM Brindisi station | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Trains from Pisa to Brindisi with Frecciarossa, Intercity Notte, and Intercity. Night trains available on this route with Intercity Notte. High-speed trains available on this route with Frecciarossa and Frecciargento. Regional trains available on this route with Regionale. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Brindisi — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brindisi trip today.
Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.
Archaeological zone and small interpretive museum preserving a Roman domus with mosaics, ideal for understanding everyday life in ancient Brindisi.
Historic site museum in a circular medieval church, appreciated for architecture and exhibits linked to pilgrims, crusaders, and the city’s past.
Brindisi’s main waterfront promenade, ideal for harbor views, evening walks, and seeing the city’s maritime life at its most atmospheric.
Historic square beside the cathedral, Roman column, and staircase, making it one of the most important and scenic urban spaces in Brindisi.
Elegant central square framed by historic buildings and cafés nearby, a practical base for sightseeing and people-watching in the old town.
Rustico leccese is a flaky pastry filled with béchamel, tomato, and mozzarella. Popular across Salento, it is a beloved snack in Brindisi bars and bakeries.
Puccia salentina is a round Apulian bread sandwich, often stuffed with tuna, olives, capers, or vegetables. It is a classic street food in Brindisi and nearby Salento.
Fave e cicorie pairs creamy pureed fava beans with wild chicory. This humble Puglian staple is deeply traditional and widely eaten in Brindisi homes and trattorias.
Refined seafood restaurant in central Brindisi, known for elegant tasting menus, polished service, and creative Apulian cuisine in a stylish setting.
Well-known traditional restaurant serving Apulian seafood and local classics. Relaxed, reliable, and popular for fresh fish near the historic center.
Casual seafood spot appreciated for raw and cooked fish dishes, simple local preparations, and an unfussy atmosphere close to the waterfront.
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Milan, while local buses and casual meals stay fairly affordable for tourists.
Service is often included or modest. Round up or leave €1-2 at cafes, 5-10% at restaurants for good service, and round up taxi fares.
Official public transport app
Brindisi Airport -> Piazza Cairoli, Brindisi
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Brindisi.
Find answers to the most common questions about traveling from Pisa to Brindisi by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

Most Pisa to Brindisi trains use the Pisa Centrale to Brindisi station pair. Use this guide to compare Pisa and Brindisi train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Pisa San Rossore is 1 km from Pisa city centre. Public transport options include:
Pisa San Rossore has practical services for this route, including Parking, Dining, Accessibility, WC, Hotel, Ticket Office, Bike Parking, and Bike Rental.
Food options include: Ristorante pizzeria, SushiKing, Ristorante Cinese Oriente
The ticket office is open 24/7.
Available at Pisa San Rossore: Parking, WC.
Available at Pisa San Rossore: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa San Rossore: Elevators on every platform. Sala Blu services can be reached at +39 0647308579.
Nearby hotels include Rosso di Sera Relais Tuscany, Le Cascine, Camping Village Torre Pendente.
Brindisi has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ristorante La Locanda del Porto, McDonald's Brindisi
Free. ATMs are available in the train station.
Ticket office support is available at Brindisi. Information desks are located in the main hall.
Luggage storage is available at Brindisi. Lost and found is available at the station.
Available at Brindisi: Parking, Taxis, WC.
Available at Brindisi: Bike Parking, Car Rental.
Accessibility facilities are available at Brindisi.
Nearby hotels include Palazzo Virgilio Hotel, Hotel Orientale, Grande Albergo Internazionale.
Check train stations information for Pisa and Brindisi, including where trains depart and arrive on this route.