Travel Information
Compare train, bus, and flight for Pisa to Brindisi
Omio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a flight which can get you there in 1h 28m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $34, and a flight costs an average of $21.
Distance: 441 miles (710 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$124 Average price | $65 Average price Cheapest | $90 Average price |
4h 28m Average total duration Fastest 1h 28m Onboard + 3h 0m Additional time* | 14h 7m Average total duration 13h 37m Onboard + 30m Additional time* | 10h 3m Average total duration 9h 33m Onboard + 30m Additional time* |
- CO2 emissions | 0.7 - 1.8kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Brindisi:
A bus is $25 (€20) less than a train for this route with tickets for a train from Pisa to Brindisi costing on average $90 (€73).
A bus is $59 (€48) less than a flight for this route with tickets for a flight from Pisa to Brindisi costing on average $124 (€101).
Other travel options to Brindisi take longer:
Train takes on average 9h 33m.
Bus takes on average 13h 37m.
Travel optionsfrom Pisa to Brindisi
How to get from Pisa to Brindisi by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Brindisi is by taking a bus because it’s the best combination of price and speed.
131 · 1087:20 PM13h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$751One-way1 transfer
Cheapest
131 · 1087:20 PM13h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$751One-way1 transfer
Fastest
FR 60196:30 PM1h30Pisa International Airport8:00 PMBrindisi Airport$2451One-way0 transfers
Other options
Regionale 18489 · Autobus TTPER B0400+
Intercity 6098:50 AM13h33Pisa Centrale10:23 PMBrindisi station$1071One-way2 transfers
Intercity 662 · Intercity 6096:42 AM15h41Pisa Centrale10:23 PMBrindisi station$1511One-way1 transfer
Regionale 4028+
FRECCIAROSSA 9416 · FRECCIAROSSA 880911:09 AM9h18Pisa Centrale8:27 PMBrindisi station$1771One-way2 transfers
2078:20 AM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:10 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$841One-way0 transfers
FlixBus · FlixBus4:45 AM17h40Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1111One-way1 transfer
FlixBus · FlixBus5:25 PM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)7:15 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1151One-way1 transfer
FR 82786:20 AM1h30Pisa International Airport7:50 AMBrindisi Airport$2451One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Pisa to Brindisi
Travel to Brindisi easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Brindisi.

This is compared to other travel options from Pisa to Brindisi:
A bus is $25 (€20) less than a train for this route with tickets for a train from Pisa to Brindisi costing on average $90 (€73).
A bus is $59 (€48) less than a flight for this route with tickets for a flight from Pisa to Brindisi costing on average $124 (€101).
Other travel options to Brindisi take longer:
Train takes on average 9h 33m.
Bus takes on average 13h 37m.
- Around 15 trains per day.
- Around 6 buses per day.
- Around 1 flights per day.
However, we recommend checking specific travel dates for your route between Pisa and Brindisi as scheduled services by train, bus, and flight can vary by season or day of the week.
- Trains mostly depart from Pisa Centrale and arrive in Brindisi station.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale).
- Flights mostly depart from Pisa International Airport and arrive in Brindisi Airport.
- Travel with Frecciarossa, Intercity Notte, Intercity, Frecciargento, Regionale to go to Brindisi by train.
- Travel with Malta Air, Ryanair to go to Brindisi by flight.
- Travel with Marino Autolinee, FlixBus to go to Brindisi by bus.
- 1 direct flights per day with Malta Air, Ryanair.
Travelling from Pisa to Brindisi: related information
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