Travel Information
Compare train, bus, and flight for Pisa to Brindisi
Omio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from $35. For those with little time consider booking a flight which can get you there in 1h 28m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $35, and a flight costs an average of $21.
Distance: 441 miles (710 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$137 Average price | $71 Average price Cheapest | $95 Average price |
4h 28m Average total duration Fastest 1h 28m Onboard + 3h 0m Additional time* | 14h 9m Average total duration 13h 39m Onboard + 30m Additional time* | 10h 12m Average total duration 9h 42m Onboard + 30m Additional time* |
- CO2 emissions | 0.7 - 1.8kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Pisa to Brindisi
How to get from Pisa to Brindisi by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Brindisi is by taking a flight because it’s the best combination of price and speed.
FR 601910:45 AM1h30Pisa International Airport12:15 PMBrindisi Airport$1061One-way0 transfers
Cheapest
131 · 1087:20 PM13h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$791One-way1 transfer
Fastest
FR 601910:45 AM1h30Pisa International Airport12:15 PMBrindisi Airport$1061One-way0 transfers
Other options
Regionale 18322 · Regionale 17852+
InterCityNotte 7558:56 PM12h09Pisa Centrale9:05 AMBrindisi station$1011One-way2 transfers
Regionale Veloce 4024 · Regionale 94455+
Intercity 6099:20 AM13h03Pisa Centrale10:23 PMBrindisi station$1071One-way2 transfers
Regionale 18264 · Regionale 94467+
Intercity 6076:38 AM13h30Pisa Centrale8:08 PMBrindisi station$1071One-way2 transfers
2078:20 AM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:10 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$961One-way0 transfers
FlixBus · FlixBus10:00 PM15h55Pisa, Via delle Fiamme Gialle (Park Pietrasantina)1:55 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1001One-way1 transfer
FlixBus · FlixBus12:25 AM16h15Pisa, Via delle Fiamme Gialle (Park Pietrasantina)4:40 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1071One-way1 transfer
FR 82788:30 PM1h30Pisa International Airport10:00 PMBrindisi Airport$1501One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Pisa to Brindisi
Travel to Brindisi easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Brindisi.

This is compared to other travel options from Pisa to Brindisi:
A flight is $13 (€11) less than a bus for this route with tickets for a bus from Pisa to Brindisi costing on average $35 (€28).
A flight is $32 (€26) less than a train for this route with tickets for a train from Pisa to Brindisi costing on average $54 (€43).
Other travel options to Brindisi take longer:
Train takes on average 8h 48m.
Bus takes on average 13h 0m.
- Around 15 trains per day.
- Around 6 buses per day.
- Around 1 flights per day.
However, we recommend checking specific travel dates for your route between Pisa and Brindisi as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Brindisi Airport.
- Trains mostly depart from Pisa Centrale and arrive in Brindisi station.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale).
- Travel with Frecciargento, Frecciarossa, Intercity Notte, Intercity, Regionale to go to Brindisi by train.
- Travel with Malta Air, Ryanair to go to Brindisi by flight.
- Travel with Marino Autolinee, FlixBus to go to Brindisi by bus.
- 1 direct flights per day with Malta Air, Ryanair.
- 1 direct buses per day with Marino Autolinee.
Travelling from Pisa to Brindisi: related information
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