Travel Information
Compare train, bus, and flight for Pisa to Brindisi
Omio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $73 For those with little time, consider booking a flight, which has an average total journey time of 3h 27m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of $73, while a flight costs an average of $138.
Distance: 441 miles (710 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$138 Average price | $73 Average price Cheapest | $86 Average price |
3h 27m Average total duration Fastest 1h 27m Onboard + 2h 0m Additional time* | 14h 2m Average total duration 13h 32m Onboard + 30m Additional time* | 10h 3m Average total duration 9h 33m Onboard + 30m Additional time* |
- CO2 emissions | 0.7 - 1.8kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Brindisi:
A bus is $13 (€11) less than a train for this route with tickets for a train from Pisa to Brindisi costing on average $86 (€70).
A bus is $65 (€52) less than a flight for this route with tickets for a flight from Pisa to Brindisi costing on average $138 (€111).
Other travel options to Brindisi take longer:
Train takes on average 10h 3m.
Bus takes on average 14h 2m.
Travel optionsfrom Pisa to Brindisi
How to get from Pisa to Brindisi by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Brindisi is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus4:45 AM17h40Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$631One-way1 transfer
Cheapest
FlixBus · FlixBus4:45 AM17h40Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$631One-way1 transfer
Fastest
FR 60196:30 PM1h30Pisa International Airport8:00 PMBrindisi Airport$1121One-way0 transfers
Other options
Regionale Veloce 4137+
InterCityNotte 7895:40 PM14h09Pisa Centrale7:49 AMBrindisi station$861One-way1 transfer
Regionale 18322 · Regionale 17852+
InterCityNotte 7559:01 PM12h04Pisa Centrale9:05 AMBrindisi station$971One-way2 transfers
Regionale 18286 · Regionale 94455+
Intercity 60910:01 AM12h22Pisa Centrale10:23 PMBrindisi station$1041One-way2 transfers
131 · 1087:20 PM13h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$751One-way1 transfer
FlixBus · FlixBus5:25 PM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)7:15 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$841One-way1 transfer
FlixBus · FlixBus12:25 AM16h15Pisa, Via delle Fiamme Gialle (Park Pietrasantina)4:40 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$841One-way1 transfer
FR 82786:20 AM1h30Pisa International Airport7:50 AMBrindisi Airport$1261One-way0 transfers
BA617 · BA5388:30 PM15h05Pisa International Airport11:35 AMBrindisi Airport$11151One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Pisa to Brindisi
Travel to Brindisi easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Brindisi.

This is compared to other travel options from Pisa to Brindisi:
A bus is $13 (€11) less than a train for this route with tickets for a train from Pisa to Brindisi costing on average $86 (€70).
A bus is $65 (€52) less than a flight for this route with tickets for a flight from Pisa to Brindisi costing on average $138 (€111).
Other travel options to Brindisi take longer:
Train takes on average 10h 3m.
Bus takes on average 14h 2m.
- Around 15 trains per day.
- Around 7 buses per day.
- Around 2 flights per day.
However, we recommend checking specific travel dates for your route between Pisa and Brindisi as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Brindisi Airport.
- Trains mostly depart from Pisa Centrale and arrive in Brindisi station.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale).
- Travel with Marino Autolinee, FlixBus to go to Brindisi by bus.
- Travel with Frecciarossa, Intercity Notte, Intercity, Frecciargento, Regionale to go to Brindisi by train.
- Travel with Malta Air, Ryanair to go to Brindisi by flight.
- 1 direct buses per day with Marino Autolinee.
- 1 direct flights per day with Malta Air.
Travelling from Pisa to Brindisi: related information
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