Travel Information
Compare train, bus, and flight for Pisa to Brindisi
Omio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price, take the train, with an average ticket price of $82 For those with little time, consider booking a flight, which has an average total journey time of 4h 43m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a train costs an average of $82, while a flight costs an average of $326.
Distance: 441 miles (710 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$326 Average price | $86 Average price | $82 Average price Cheapest |
4h 43m Average total duration Fastest 2h 43m Onboard + 2h 0m Additional time* | 13h 37m Average total duration 13h 7m Onboard + 30m Additional time* | 10h 39m Average total duration 10h 9m Onboard + 30m Additional time* |
- CO2 emissions | 0.7 - 1.8kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Pisa to Brindisi
Compare the available ways to get from Pisa to Brindisi, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Pisa to Brindisi:
A train is $5 less than a bus for this route with tickets for a bus from Pisa to Brindisi costing on average $86.
A train is $245 less than a flight for this route with tickets for a flight from Pisa to Brindisi costing on average $326.
Other travel options to Brindisi take longer:
Train takes on average 10h 39m.
Bus takes on average 13h 37m.
Travel optionsfrom Pisa to Brindisi
How to get from Pisa to Brindisi by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Brindisi is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus6:05 AM16h20Pisa (Pisamover via San Giusto/Aurelia)10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$491One-way2 transfers
Cheapest
FlixBus · FlixBus · FlixBus6:05 AM16h20Pisa (Pisamover via San Giusto/Aurelia)10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$491One-way2 transfers
Fastest
FR 60196:45 PM1h25Pisa International Airport8:10 PMBrindisi Airport$731One-way0 transfers
Other options
Regionale 18286 · Regionale 94455+
Intercity 60910:01 AM12h22Pisa Centrale10:23 PMBrindisi station$841One-way2 transfers
Regionale Veloce 4014 · Regionale 17816+
Intercity 6077:38 AM12h34Pisa Centrale8:12 PMBrindisi station$871One-way2 transfers
Regionale 2294+
Intercity 6076:00 AM14h12Pisa Centrale8:12 PMBrindisi station$931One-way1 transfer
FlixBus · FlixBus12:25 AM16h15Pisa, Via delle Fiamme Gialle (Park Pietrasantina)4:40 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$541One-way1 transfer
131 · 1087:20 PM13h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$581One-way1 transfer
FlixBus · FlixBus4:45 AM17h40Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$591One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Pisa to Brindisi
Travel to Brindisi easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Brindisi.

This is compared to other travel options from Pisa to Brindisi:
A train is $5 less than a bus for this route with tickets for a bus from Pisa to Brindisi costing on average $86.
A train is $245 less than a flight for this route with tickets for a flight from Pisa to Brindisi costing on average $326.
Other travel options to Brindisi take longer:
Train takes on average 10h 39m.
Bus takes on average 13h 37m.
- Around 19 trains per day.
- Around 7 buses per day.
- Around 2 flights per day.
However, we recommend checking specific travel dates for your route between Pisa and Brindisi as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Brindisi Airport.
- Trains mostly depart from Pisa Centrale and arrive in Brindisi station.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale).
- Travel with Malta Air, Swiss, Air Dolomiti, Air Baltic, Helvetic Airways, British Airways, Edelweiss Air to go to Brindisi by flight.
- Travel with Marino Autolinee, FlixBus to go to Brindisi by bus.
- Travel with Frecciarossa, Intercity Notte, Intercity, Frecciargento, Regionale to go to Brindisi by train.
- 1 direct flights per day with Malta Air.
- 1 direct buses per day with Marino Autolinee.
Travelling from Pisa to Brindisi: related information
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