- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
The best way to find a cheap bus ticket from Paducah, KY to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Paducah, KY to St. Louis, MO will cost around €37 if you buy it on the day, but the cheapest tickets can be found for only €37.
On Tue, Nov 03, we found 1 buses from Paducah, KY to St. Louis, MO, including 1 direct services.
On Tue, Nov 03 the direct buses cover the 222 km distance in an average of 3 h 35 m but if you time it right, some buses will get you there in just 3 h 35 m .
On Tue, Nov 03 the slowest buses will take 3 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Paducah, KY to St. Louis, MO run on average 1 times per day, taking around 3h 25m. Cheap bus tickets for this journey start at €24 if you book in advance.
There are 1 buses per day. The earliest bus runs at 01:05, the last at 23:45. The fastest bus covers the 137 miles (222 km) distance in 3h 25m.
Distance 137 miles (222 km) |
Average bus duration 3h 25m |
Cheapest ticket price €24 |
Buses per day 1 |
Direct buses 1 |
Fastest bus 3h 25m |
First bus 1:05 AM |
Last bus 11:45 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 7 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Paducah, KY to St. Louis, MO.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 10:35AM | Arrival Time 02:10PM | Duration 3h35 | Departure days Mon, Tue | Cheapest price €37 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 02:35PM | Duration 3h30 | Departure days Mon, Thu, Fri | Cheapest price €29 |
Operator FlixBus | Departure Time 11:35AM | Arrival Time 03:10PM | Duration 3h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price €29 |
The table below shows live departures for Paducah, KY to St. Louis, MO buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:35 AM Paducah, KY | 3h35 | 2:10 PM St. Louis, MO | 0 transfersDirect | |
![]() | 11:05 AM Paducah, KY | 3h30 | 2:35 PM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in St. Louis, MO.
Find answers to the most common questions about traveling from Paducah, KY to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Paducah, KY to St. Louis, MO buses use the Paducah, Irvin Cobb Dr (Bus Terminal) to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Paducah, KY and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Paducah, Irvin Cobb Dr (Bus Terminal) is 3 km from Paducah city centre. Public transport options include:
Paducah, Irvin Cobb Dr (Bus Terminal) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby fast food options available.
Wi-Fi is available at Paducah, Irvin Cobb Dr (Bus Terminal). ATMs are available at Paducah, Irvin Cobb Dr (Bus Terminal).
Ticket office support is available at Paducah, Irvin Cobb Dr (Bus Terminal).
Available at Paducah, Irvin Cobb Dr (Bus Terminal): Parking, Taxis, WC.
Accessibility facilities are available at Paducah, Irvin Cobb Dr (Bus Terminal): Basic accessibility available.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Check bus stations information for Paducah, KY and St. Louis, MO, including where buses depart and arrive on this route.
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