- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price
$84
Average price
$134
Fastest journey
9 h 25 m
Average duration
11 h 57 m
Buses per day
5
Distance
738 km
The best way to find a cheap bus ticket from Oklahoma City, OK to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Oklahoma City, OK to St. Louis, MO will cost around $134 if you buy it on the day, but the cheapest tickets can be found for only $84.
Of the 5 buses that leave Oklahoma City, OK for St. Louis, MO on Sat, Aug 15, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Aug 15 the direct buses cover the 738 km distance in an average of 11 h 57 m but if you time it right, some buses will get you there in just 9 h 25 m .
On Sat, Aug 15 the slowest buses will take 17 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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FlixBus

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FlixBusOmio recommends booking the train as it is the most popular option from Oklahoma City, OK to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a flight which can get you there in 4h 46m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of $62, and a flight costs an average of $177.
Distance: 458 miles (738 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$84 Average price Cheapest | $146 Average price | $280 Average price | $111 Average price (fuel + tolls) |
11h 26m Average total duration 10h 56m Onboard + 30m Additional time* | 19h 32m Average total duration 19h 2m Onboard + 30m Additional time* | 7h 46m Average total duration Fastest 4h 46m Onboard + 3h 0m Additional time* | 7h 6m Average total duration (door-to-door) |
0.7 - 1.8kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | 2.2 - 4.4kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Oklahoma City, OK to St. Louis, MO:
A bus is $61 (€50) less than a train for this route with tickets for a train from Oklahoma City, OK to St. Louis, MO costing on average $146 (€118).
A bus is $196 (€159) less than a flight for this route with tickets for a flight from Oklahoma City, OK to St. Louis, MO costing on average $280 (€227).
Other travel options to St. Louis, MO take longer:
Bus takes on average 10h 56m.
Train takes on average 19h 2m.
Tickets start at around $84 (€68) compared to roughly $111 (€90) in fuel and tolls — a saving of about $27 (€22). The journey takes 10h 56m versus 7h 6m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:20AM | Arrival Time 12:55PM | Duration 12h35 | Departure days Everyday | Cheapest price $78 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 10:45PM | Duration 10h35 | Departure days Everyday | Cheapest price $63 |
Operator Greyhound | Departure Time 09:45PM | Arrival Time 07:10AM | Duration 9h25 | Departure days Everyday | Cheapest price $65 |
Operator Greyhound | Departure Time 10:40PM | Arrival Time 03:45PM | Duration 17h05 | Departure days Everyday | Cheapest price $79 |
The table below shows live departures for Oklahoma City, OK to St. Louis, MO buses for today, Friday, August 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:10 PM Oklahoma City, E Reno Ave (Greyhound Bus Station), OK | 10h05 | 10:15 PM St. Louis, Lambert International Airport | 0 transfersDirect | |
![]() | 12:10 PM Oklahoma City, E Reno Ave (Greyhound Bus Station), OK | 10h35 | 10:45 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
![]() | 9:45 PM Oklahoma City, E Reno Ave (Greyhound Bus Station), OK | 9h25 | 7:10 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
+ FlixBus | 10:40 PM Oklahoma City, E Reno Ave (Greyhound Bus Station), OK | 17h05 | 3:45 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| Saturday, August 15 | |||||
· | 12:20 AM Oklahoma City, E Reno Ave (Greyhound Bus Station), OK | 12h35 | 12:55 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Oklahoma City, OK to St. Louis, MO run on average 6 times per day, taking around 10h 56m. Cheap bus tickets for this journey start at $62 (€50) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:15, the last at 23:50. The fastest bus covers the 458 miles (738 km) distance in 9h 25m.
Distance 458 miles (738 km) |
Average bus duration 10h 56m |
Cheapest ticket price $62 (€50) |
Buses per day 6 |
Direct buses 3 |
Fastest bus 9h 25m |
First bus 12:15 AM |
Last bus 11:50 PM |
Cheapest Month Jan |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 21 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Oklahoma City, OK to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Oklahoma City, OK to St. Louis, MO buses use the Oklahoma City, E Reno Ave (Greyhound Bus Station) to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Oklahoma City, OK and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Oklahoma City, E Reno Ave (Greyhound Bus Station) is 3 km from Oklahoma City city centre. Public transport options include:
Oklahoma City, E Reno Ave (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available inside the station. ATMs are available at Oklahoma City, E Reno Ave (Greyhound Bus Station).
Ticket office support is available at Oklahoma City, E Reno Ave (Greyhound Bus Station).
Available at Oklahoma City, E Reno Ave (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Oklahoma City, E Reno Ave (Greyhound Bus Station): Wheelchair accessible entrances and restrooms.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
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