Travel Information
Compare bus, train, and flight for Milan to Syracuse
Omio recommends booking the train as it is the most popular option from Milan to Syracuse among Omio's users. If you are prioritising price, take the train, with an average ticket price of €84 For those with little time, consider booking a train, which has an average total journey time of 16h 25m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.3 - 1.0kg. Average ticket prices depend on the travel mode: a train costs an average of €84, while a bus costs an average of €106.
Distance: 659 miles (1061 km)
Compare train with
Most popular Train | Bus |
|---|---|
€84 Average price Cheapest | €106 Average price |
16h 25m Average total duration Fastest 15h 55m Onboard + 30m Additional time* | 21h 28m Average total duration 20h 58m Onboard + 30m Additional time* |
0.3 - 1.0kg CO2 emissions Lowest | 1.1 - 2.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Syracuse:
A train is €22 less than a bus for this route with tickets for a bus from Milan to Syracuse costing on average €106.
Other travel options to Syracuse take longer:
Bus takes on average 21h 28m.
Travel optionsfrom Milan to Syracuse
How to get from Milan to Syracuse by train, bus or flight.
Our recommendation
The best way to travel from Milan to Syracuse is by taking a flight because it’s the best combination of price and speed.
W464673:15 PM2h00Milan Malpensa Airport5:15 PMCatania Fontanarossa Airport€321One-way0 transfers
Cheapest
W464673:15 PM2h00Milan Malpensa Airport5:15 PMCatania Fontanarossa Airport€321One-way0 transfers
Fastest
U2353911:30 AM1h50Milan Malpensa Airport1:20 PMCatania Fontanarossa Airport€561One-way0 transfers
Other options
InterCityNotte 797+
Intercity 723+
BUS L721A9:13 PM23h33Milan Porta Garibaldi8:46 PMSyracuse station€1301One-way2 transfers
FRECCIAROSSA 9649+
InterCityNotte 1955+
treno 5383 effettuato con bus PA5194:58 PM16h51Milan Centrale9:49 AMSyracuse station€1701One-way2 transfers
FRECCIAROSSA 9663+
InterCityNotte 95063+
BUS L959F7:35 PM17h41Milan Centrale1:16 PMSyracuse station€1801One-way2 transfers
FlixBus · FlixBus1:05 PM20h10Milano, Autostazione Lampugnano9:15 AMSyracuse, Corso Umberto I€441One-way1 transfer
FlixBus · FlixBus9:10 PM23h30Milano, San Donato - Settore B (Viale Giuseppe Impastato)8:40 PMSyracuse, Corso Umberto I€471One-way1 transfer
FlixBus · FlixBus8:35 PM24h05Milano, Autostazione Lampugnano8:40 PMSyracuse, Corso Umberto I€471One-way1 transfer
W464657:50 PM2h10Milan Malpensa Airport10:00 PMCatania Fontanarossa Airport€321One-way0 transfers
U235356:40 AM1h55Milan Malpensa Airport8:35 AMCatania Fontanarossa Airport€551One-way0 transfers
U235477:05 PM1h55Milan Malpensa Airport9:00 PMCatania Fontanarossa Airport€551One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Milan to Syracuse
Travel to Syracuse easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Syracuse.

This is compared to other travel options from Milan to Syracuse:
A train is €22 less than a bus for this route with tickets for a bus from Milan to Syracuse costing on average €106.
Other travel options to Syracuse take longer:
Bus takes on average 21h 28m.
- Around 31 trains per day.
- Around 3 buses per day.
However, we recommend checking specific travel dates for your route between Milan and Syracuse as scheduled services by bus, train, and flight can vary by season or day of the week.
- Trains mostly depart from Milan Centrale and arrive in Syracuse station.
- Buses mostly depart from Milano, Autostazione Lampugnano and arrive in Syracuse, Corso Umberto I.
- Travel with FlixBus to go to Syracuse by bus.
- Travel with Intercity Notte, Intercity to go to Syracuse by train.
- 0 direct trains per day with Intercity Notte.
Travelling from Milan to Syracuse: related information
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