Travel Information
Compare bus, train, and flight for Milan to Syracuse
Omio recommends booking the train as it is the most popular option from Milan to Syracuse among Omio's users. If you are prioritising price take the flight with prices starting from $74. For those with little time consider booking a flight which can get you there in 1h 49m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 1.0kg. The ticket price range depends on the travel mode: a flight costs an average of $74, and a train costs an average of $74.
Distance: 659 miles (1061 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$147 Average price | $104 Average price | $79 Average price Cheapest |
15h 12m Average total duration 14h 42m Onboard + 30m Additional time* | 21h 14m Average total duration 20h 44m Onboard + 30m Additional time* | 3h 49m Average total duration Fastest 1h 49m Onboard + 2h 0m Additional time* |
0.3 - 1.0kg CO2 emissions Lowest | 1.1 - 2.6kg CO2 emissions | 3.2 - 6.4kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Syracuse:
A flight is $25 (€20) less than a bus for this route with tickets for a bus from Milan to Syracuse costing on average $104 (€84).
A flight is $68 (€55) less than a train for this route with tickets for a train from Milan to Syracuse costing on average $147 (€119).
Other travel options to Syracuse take longer:
Train takes on average 14h 42m.
Bus takes on average 20h 44m.
Travel optionsfrom Milan to Syracuse
How to get from Milan to Syracuse by train, bus or flight.
Our recommendation
The best way to travel from Milan to Syracuse is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus1:05 PM20h10Milano, Autostazione Lampugnano9:15 AMSyracuse, Corso Umberto I$921One-way1 transfer
Cheapest
FlixBus · FlixBus1:05 PM20h10Milano, Autostazione Lampugnano9:15 AMSyracuse, Corso Umberto I$921One-way1 transfer
Fastest
FRECCIAROSSA 9515+
Intercity 7277:00 AM15h38Milan Centrale10:38 PMSyracuse station$1541One-way1 transfer
Other options
InterCityNotte 797+
Intercity 72310:18 PM20h13Milan Porta Garibaldi6:31 PMSyracuse station$1111One-way1 transfer
Intercity 597 · Intercity 594+
InterCityNotte 19591:48 PM22h37Milan Centrale12:25 PMSyracuse station$1541One-way2 transfers
FRECCIAROSSA 9559+
InterCityNotte 19595:50 PM18h35Milan Centrale12:25 PMSyracuse station$1621One-way1 transfer
FlixBus · FlixBus9:10 PM23h30Milano, San Donato - Settore B (Viale Giuseppe Impastato)8:40 PMSyracuse, Corso Umberto I$1041One-way1 transfer
FlixBus · FlixBus8:35 PM24h05Milano, Autostazione Lampugnano8:40 PMSyracuse, Corso Umberto I$1041One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Milan to Syracuse
Travel to Syracuse easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Syracuse.

This is compared to other travel options from Milan to Syracuse:
A flight is $25 (€20) less than a bus for this route with tickets for a bus from Milan to Syracuse costing on average $104 (€84).
A flight is $68 (€55) less than a train for this route with tickets for a train from Milan to Syracuse costing on average $147 (€119).
Other travel options to Syracuse take longer:
Train takes on average 14h 42m.
Bus takes on average 20h 44m.
- Around 45 flights per day.
- Around 6 trains per day.
- Around 3 buses per day.
- Around 1 ferries per day.
However, we recommend checking specific travel dates for your route between Milan and Syracuse as scheduled services by bus, train, and flight can vary by season or day of the week.
- Trains mostly depart from Milan Centrale and arrive in Syracuse station.
- Buses mostly depart from Milano, Autostazione Lampugnano and arrive in Syracuse, Corso Umberto I.
- Flights mostly depart from Milan Linate Airport and arrive in Catania Fontanarossa Airport.
- Travel with Intercity Notte, Intercity, Frecciarossa, Frecciargento to go to Syracuse by train.
- Travel with easyJet, ITA, Malta Air, Ryanair to go to Syracuse by flight.
- Travel with FlixBus to go to Syracuse by bus.
- 1 direct trains per day with Intercity Notte.
- 15 direct flights per day with easyJet, ITA, Malta Air, Ryanair.
Travelling from Milan to Syracuse: related information
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