- Must visit
Museo Civico
Siena’s main civic museum displays Lorenzetti’s frescoes and superb medieval art inside the historic town hall. It is essential for understanding the city.










Cheapest price
$20
Average price
$33
Fastest journey
3h 30m
Average duration
4h 58m
Buses per day
13
Distance
285 km
Omio recommends booking the bus as it is the most popular option from Milan to Siena among Omio's users. If you are prioritising price take the bus with prices starting from $8. For those with little time consider booking a train which can get you there in 4h 38m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $8, and a flight costs an average of $166.
Distance: 182 miles (293 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$18 Average price Cheapest | $52 Average price | $174 Average price | $112 Average price (fuel + tolls) |
5h 20m Average total duration 4h 50m Onboard + 30m Additional time* | 5h 8m Average total duration Fastest 4h 38m Onboard + 30m Additional time* | 12h 23m Average total duration 9h 23m Onboard + 3h 0m Additional time* | 4h 5m Average total duration (door-to-door) |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Siena:
A bus is $34 (€28) less than a train for this route with tickets for a train from Milan to Siena costing on average $52 (€43).
A bus is $156 (€129) less than a flight for this route with tickets for a flight from Milan to Siena costing on average $174 (€143).
Other travel options to Siena take longer:
Bus takes on average 4h 50m.
Flight takes on average 9h 23m.
Tickets start at around $18 (€14) compared to roughly $112 (€93) in fuel and tolls — a saving of about $95 (€78). The journey takes 4h 50m versus 4h 5m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, Itabus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:35AM | Arrival Time 05:30AM | Duration 4h55 | Departure days Mon, Tue, Fri, Sun | Cheapest price $25 |
Operator FlixBus | Departure Time 01:10AM | Arrival Time 05:30AM | Duration 4h20 | Departure days Mon, Tue, Fri, Sun | Cheapest price $25 |
Operator FlixBus | Departure Time 02:25AM | Arrival Time 08:40AM | Duration 6h15 | Departure days Mon, Tue, Fri | Cheapest price $47 |
Operator BlaBlaCar | Departure Time 04:00AM | Arrival Time 07:40AM | Duration 3h40 | Departure days Tue, Sun | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 04:40AM | Arrival Time 08:40AM | Duration 4h00 | Departure days Sat | Cheapest price $32 |
Operator BlaBlaCar | Departure Time 05:00AM | Arrival Time 08:30AM | Duration 3h30 | Departure days Wed | Cheapest price $26 |
Operator BlaBlaCar | Departure Time 05:20AM | Arrival Time 08:50AM | Duration 3h30 | Departure days Thu | Cheapest price $32 |
Operator FlixBus | Departure Time 05:35AM | Arrival Time 11:20AM | Duration 5h45 | Departure days Mon, Fri, Sat, Sun | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 06:00AM | Arrival Time 09:30AM | Duration 3h30 | Departure days Thu | Cheapest price $30 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 12:30PM | Duration 6h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $18 |
Operator BlaBlaCar | Departure Time 06:20AM | Arrival Time 10:10AM | Duration 3h50 | Departure days Wed | Cheapest price $32 |
Operator BlaBlaCar | Departure Time 06:30AM | Arrival Time 10:10AM | Duration 3h40 | Departure days Sat | Cheapest price $38 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 12:30PM | Duration 5h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $18 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 10:40AM | Duration 3h40 | Departure days Mon | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 07:20AM | Arrival Time 11:50AM | Duration 4h30 | Departure days Tue | Cheapest price $32 |
Operator FlixBus | Departure Time 08:00AM | Arrival Time 02:20PM | Duration 6h20 | Departure days Thu, Sat | Cheapest price $48 |
Operator BlaBlaCar | Departure Time 08:10AM | Arrival Time 12:10PM | Duration 4h00 | Departure days Sat | Cheapest price $24 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 02:55PM | Duration 6h40 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $21 |
Operator FlixBus | Departure Time 08:20AM | Arrival Time 02:55PM | Duration 6h35 | Departure days Everyday | Cheapest price $19 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 02:55PM | Duration 6h05 | Departure days Sun | Cheapest price $59 |
Operator Itabus | Departure Time 08:55AM | Arrival Time 04:20PM | Duration 7h25 | Departure days Tue | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 12:40PM | Duration 3h40 | Departure days Wed, Fri, Sat | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 01:50PM | Duration 4h20 | Departure days Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 02:40PM | Duration 5h00 | Departure days Mon, Thu, Fri, Sat | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 09:40AM | Arrival Time 01:10PM | Duration 3h30 | Departure days Thu | Cheapest price $27 |
Operator Itabus | Departure Time 09:45AM | Arrival Time 04:20PM | Duration 6h35 | Departure days Tue | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 09:50AM | Arrival Time 01:20PM | Duration 3h30 | Departure days Mon | Cheapest price $33 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 03:00PM | Duration 5h00 | Departure days Sun | Cheapest price $33 |
Operator FlixBus | Departure Time 10:20AM | Arrival Time 07:40PM | Duration 9h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $43 |
Operator Itabus | Departure Time 10:40AM | Arrival Time 04:20PM | Duration 5h40 | Departure days Everyday | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 10:50AM | Arrival Time 02:40PM | Duration 3h50 | Departure days Thu | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 03:20PM | Duration 4h20 | Departure days Sun | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 11:40AM | Arrival Time 03:00PM | Duration 3h20 | Departure days Fri | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 03:30PM | Duration 3h30 | Departure days Thu | Cheapest price $24 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 07:40PM | Duration 7h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 12:25PM | Arrival Time 06:15PM | Duration 5h50 | Departure days Everyday | Cheapest price $19 |
Operator Itabus | Departure Time 12:35PM | Arrival Time 05:50PM | Duration 5h15 | Departure days Tue, Wed | Cheapest price $30 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 06:55PM | Duration 6h10 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $43 |
Operator BlaBlaCar | Departure Time 01:00PM | Arrival Time 04:30PM | Duration 3h30 | Departure days Mon, Fri | Cheapest price $32 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 05:30PM | Duration 3h30 | Departure days Tue | Cheapest price $29 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 08:00PM | Duration 5h35 | Departure days Thu | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 07:00PM | Duration 4h30 | Departure days Fri, Sun | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 02:40PM | Arrival Time 06:10PM | Duration 3h30 | Departure days Sun | Cheapest price $29 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 07:50PM | Duration 5h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $20 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 06:40PM | Duration 3h40 | Departure days Wed, Sat | Cheapest price $21 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 10:20PM | Duration 6h50 | Departure days Everyday | Cheapest price $16 |
Operator BlaBlaCar | Departure Time 03:40PM | Arrival Time 07:20PM | Duration 3h40 | Departure days Mon | Cheapest price $33 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 10:20PM | Duration 6h00 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $22 |
Operator BlaBlaCar | Departure Time 04:20PM | Arrival Time 07:40PM | Duration 3h20 | Departure days Mon | Cheapest price $38 |
Operator BlaBlaCar | Departure Time 04:30PM | Arrival Time 08:50PM | Duration 4h20 | Departure days Tue | Cheapest price $33 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 10:20PM | Duration 5h50 | Departure days Everyday | Cheapest price $16 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 08:30PM | Duration 3h30 | Departure days Tue | Cheapest price $35 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 10:20PM | Duration 5h15 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $22 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 10:20PM | Duration 4h50 | Departure days Fri | Cheapest price $29 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 05:30AM | Duration 7h30 | Departure days Wed | Cheapest price $58 |
Operator Itabus | Departure Time 10:45PM | Arrival Time 05:10AM | Duration 6h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $24 |
Operator Itabus | Departure Time 11:30PM | Arrival Time 05:10AM | Duration 5h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $24 |
The table below shows live departures for Milan to Siena buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 12:25 PM Milano, Autostazione Lampugnano | 5h50 | 6:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2401 | 12:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h15 | 5:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus · FlixBus | 12:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 6h10 | 6:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus | 3:30 PM Milano, Autostazione Lampugnano | 6h50 | 10:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 4:20 PM Milano, Autostazione Lampugnano | 6h00 | 10:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 4:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h50 | 10:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 5:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h15 | 10:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
| Wednesday, July 15 | |||||
FlixBus · FlixBus | 8:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 6h40 | 2:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus | 8:20 AM Milano, Autostazione Lampugnano | 6h35 | 2:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2125 | 10:40 AM Milano, Autostazione Lampugnano | 5h40 | 4:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milan to Siena run on average 21 times per day, taking around 4h 50m. Cheap bus tickets for this journey start at $8 (€7) if you book in advance.
There are 18 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 182 miles (293 km) distance in 5h 15m.
Distance 182 miles (293 km) |
Average bus duration 4h 50m |
Cheapest ticket price $8 (€7) |
Buses per day 21 |
Direct buses 18 |
Fastest bus 5h 15m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 21 days |
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
Siena’s main civic museum displays Lorenzetti’s frescoes and superb medieval art inside the historic town hall. It is essential for understanding the city.
This major museum complex occupies a former hospital and combines archaeology, frescoes, chapels, and underground spaces in a memorable setting.
The cathedral museum preserves sculptures, stained glass, and treasures from the Duomo complex, including close views of masterpieces and architecture.
Siena’s iconic shell-shaped square is the social and visual heart of the city, perfect for architecture, people-watching, and understanding the Palio.
This broad square in front of the cathedral frames some of Siena’s finest Gothic monuments and is a natural stop on any walking route.
The city’s main pedestrian street links major sights with shops and noble facades. It is ideal for a first walk through Siena’s historic core.
Thick rustic soup of bread, beans, cavolo nero and vegetables. A Tuscan staple in Siena, prized for peasant roots and deep, comforting flavor.
Dense vegetable and bread soup made with beans, tomato, onion, celery and stale bread. Traditional cucina povera, often linked to Sienese home cooking.
Hand-rolled thick spaghetti, usually served with rich garlic-forward tomato sauce or duck ragù. A classic Tuscan pasta common in Siena trattorie.
Popular central trattoria focused on pici, ribollita and other regional staples, offering a casual atmosphere near major sights.
Well-known osteria for classic Tuscan and Sienese dishes, with a cozy brick interior and strong local wine selection.
Elegant Michelin-starred restaurant near Piazza del Campo, known for refined Tuscan tasting menus and polished historic atmosphere.
Moderate for Italy: lodging and dining cost more than small towns, but transit is limited and many sights are walkable.
Service is often included or covered by coperto. Round up or leave 5-10% for great restaurant service; taxis are usually rounded up; cafés need no tip.
Find answers to the most common questions about traveling from Milan to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

Most Milan to Siena buses use the Milano, Autostazione Lampugnano to Siena, Stazione FS (Piazzale Carlo Rosselli) station pair, with some services arriving at Siena, Siena/Viale Pietro Toselli. Use this guide to compare Milan and Siena bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Here are some other resources that might have the information you need