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The cheapest and fastest buses from Brindisi to Siena
Showing times and prices for Mar 21
Cheapest price
$34
Average price
$61
Fastest journey
11 h 15 m
Average duration
11 h 45 m
Buses per day
11
Distance
622 km
Cheap tickets
The best way to find a cheap bus ticket from Brindisi to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Siena will cost around $61 if you buy it on the day, but the cheapest tickets can be found for only $34.
Fast buses
Of the 11 buses that leave Brindisi for Siena on Sat, Mar 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 21 the direct buses cover the 622 km distance in an average of 11 h 45 m but if you time it right, some buses will get you there in just 11 h 15 m .
On Sat, Mar 21 the slowest buses will take 11 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1104 · 249412:05PM12h59
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)01:04AMSiena, Stazione FS (Piazzale Carlo Rosselli)
$341One-way
1 transfer
1108 · 212610:50PM12h00
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)10:50AMSiena, Stazione FS (Piazzale Carlo Rosselli)
$421One-way
1 transfer
FlixBus · FlixBus11:30PM11h55
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)11:25AMSiena, Stazione FS (Piazzale Carlo Rosselli)
$541One-way
1 transfer
FlixBus · FlixBus09:30PM11h45
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)09:15AMSiena, Stazione FS (Piazzale Carlo Rosselli)
$551One-way
1 transfer
10708:50PM11h55
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)08:45AMSiena, Stazione FS (Piazzale Carlo Rosselli)
$601One-way
0 transfers
20605:35AM11h15
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)04:50PMSiena, Stazione FS (Piazzale Carlo Rosselli)
$621One-way
0 transfers
FlixBus · FlixBus09:30PM11h45
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)09:15AMSiena, Stazione FS (Piazzale Carlo Rosselli)
$551One-way
1 transfer
FlixBus · FlixBus09:55AM11h54
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)09:49PMSiena, Siena/Viale Pietro Toselli
$731One-way
1 transfer
FlixBus · FlixBus11:30PM11h55
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)11:25AMSiena, Stazione FS (Piazzale Carlo Rosselli)
$541One-way
1 transfer
10708:50PM11h55
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)08:45AMSiena, Stazione FS (Piazzale Carlo Rosselli)
$601One-way
0 transfers
Travel Information
Compare bus, train, and flight for Brindisi to Siena
Omio recommends booking the bus as it is the most popular option from Brindisi to Siena among Omio's users. If you are prioritising price take the bus with prices starting from $23. For those with little time consider booking a flight which can get you there in 1h 30m. The ticket price range depends on the travel mode: a bus costs an average of $23, and a flight costs an average of $21.
Distance: 386 miles (622 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$48 Average price Cheapest | $117 Average price | $92 Average price |
11h 29m Average total duration 10h 59m Onboard + 30m Additional time* | 4h 30m Average total duration Fastest 1h 30m Onboard + 3h 0m Additional time* | 10h 25m Average total duration 9h 55m Onboard + 30m Additional time* |
Most popular bus company |  Most popular airline |  Most popular train company |
Direct Options | Direct Options | Direct Options |
Brindisi to Siena Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 05:30AM | Arrival Time 06:30PM | Duration 13h00 | Departure days Sat | Cheapest price $67 |
Operator Marino Autolinee | Departure Time 05:35AM | Arrival Time 04:50PM | Duration 11h15 | Departure days Sat | Cheapest price $62 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 09:49PM | Duration 11h54 | Departure days Sat | Cheapest price $73 |
Operator FlixBus | Departure Time 10:35AM | Arrival Time 12:40AM | Duration 14h05 | Departure days Sat | Cheapest price $74 |
Operator Itabus | Departure Time 12:05PM | Arrival Time 01:04AM | Duration 12h59 | Departure days Sat | Cheapest price $34 |
Operator Marino Autolinee | Departure Time 08:50PM | Arrival Time 08:45AM | Duration 11h55 | Departure days Sat | Cheapest price $60 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 09:15AM | Duration 11h45 | Departure days Sat | Cheapest price $55 |
Operator Itabus | Departure Time 10:50PM | Arrival Time 10:50AM | Duration 12h00 | Departure days Sat | Cheapest price $42 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 11:25AM | Duration 11h55 | Departure days Sat | Cheapest price $54 |
Live departures
Brindisi to Siena bus times
The table below shows live departures for Brindisi to Siena buses for tomorrow, Friday, March 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at 2:31 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1120 · 2490 | 4:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h00 | 5:30 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
| 206 | 4:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 11h15 | 3:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
| FlixBus · FlixBus | 8:55 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 11h54 | 8:49 PM Siena, Siena/Viale Pietro Toselli | 1 transfer | |
| FlixBus · FlixBus | 8:55 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 12h00 | 8:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
| FlixBus · FlixBus | 9:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h05 | 11:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
| 1104 · 2494 | 11:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 12h59 | 12:04 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brindisi to Siena by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sat
Mar 21
Mar 21
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Mar 22
Mar 22
Mon
Mar 23
Mar 23
Tue
Mar 24
Mar 24
Wed
Mar 25
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Mar 26
Fri
Mar 27
Mar 27
Why should you book Brindisi to Siena buses with Omio?
Marino Autolinee as well as Itabus or FlixBus offer buses services from Brindisi to Siena.
Omio is an official ticket reseller for all your travel options from Brindisi to Siena.
Why book with Omio vs Marino Autolinee?
- Compare with other providers: On Omio, you can not only buy tickets for Marino Autolinee, but also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Brindisi to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Marino Autolinee with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Brindisi to Siena.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Brindisi to Siena.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Brindisi to Siena.
Journey information
Overview: Bus from Brindisi to Siena
ItalyItaly
Buses from Brindisi to Siena run on average 12 times per day, taking around 10h 59m. Cheap bus tickets for this journey start at $23 (€19) but you can travel from only $21 (€17) by flight.
There are 2 buses per day. The earliest bus runs at 00:05, the last at 23:39. The fastest bus covers the 386 miles (622 km) distance in 10h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Distance 386 miles (622 km) |
Average bus duration 10h 59m |
Cheapest ticket price $23 (€19) |
Buses per day 12 |
Direct buses 2 |
Fastest bus 10h 35m |
First bus 00:05 |
Last bus 23:39 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Bus providers: Marino Autolinee, Itabus, FlixBus from Brindisi to SienaYou can travel by bus between Brindisi to Siena with Marino Autolinee, Itabus, FlixBus for as low as $21 (€17). When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Duration
11h 15m
Cheapest Price
$63 (€52)
Marino Autolinee frequency
1 a day
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Itabus
About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
10h 35m
Cheapest Price
$23 (€19)
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
11h 54m
Cheapest Price
$28 (€23)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
FAQs: Bus from Brindisi to Siena
Find answers to the most common questions about traveling from Brindisi to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Brindisi to Siena can start from as little as $23 (€19) when you book in advance. The average bus ticket price for Brindisi to Siena is $48 (€39) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Brindisi to Siena is 10h 35m to travel the 386 miles (622 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Brindisi to Siena leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Brindisi to Siena leaves at 11:39 PM.
Yes, there are 2 direct buses a day from Brindisi to Siena with Marino Autolinee. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Brindisi to Siena, you can count on Marino Autolinee, Itabus, FlixBus for the best way to get you to Siena. You can also check all possible bus companies who offer a service between Brindisi and Siena and compare the amenities they offer before buying a bus ticket.
A trip to Siena from Brindisi is worth doing but not as a day trip with a journey time of 10h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Brindisi to Siena is February.
It's helpful to compare your options as there are 3 ways to travel between Brindisi and Siena including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Brindisi to Siena:
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
Yes, there are bathrooms on board the bus from Brindisi to Siena for bus company Marino Autolinee, Itabus, FlixBus.
Some of the most interesting sights to explore in Siena are:
- Piazza del Campo, a shell-shaped medieval square known for hosting the Palio horse race and surrounded by historic buildings
- Siena Cathedral, a stunning example of Italian Romanesque-Gothic architecture featuring intricate marble work and art by famous masters
- Palazzo Pubblico, a Gothic town hall with the Torre del Mangia offering panoramic views of the city
- Basilica of San Domenico, a large church housing relics of Saint Catherine of Siena and notable frescoes
- Santa Maria della Scala, a former hospital turned museum complex showcasing art and history exhibitions.
The best things to do in Siena include:
- Torre del Mangia, a tall tower offering panoramic views of the city and surrounding countryside
- Museo dell'Opera del Duomo, a museum housing an impressive collection of religious art and artifacts
- Fortezza Medicea, a historic fortress offering beautiful views and a peaceful park for relaxation
- Enoteca Italiana, a wine museum and tasting center where you can explore and enjoy Italian wines
- Take a cooking class to learn how to make traditional Tuscan dishes.
Whether you can cancel your bus ticket from Brindisi to Siena depends on the bus companies:
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company Marino Autolinee, Itabus, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Brindisi to Siena.
Yes, the following luggage options are included when booking a bus ticket from Brindisi to Siena:
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Brindisi to Siena:
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
Yes, you can bring your pet on the bus from Brindisi to Siena. The following conditions apply:
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Brindisi to Siena with the following bus company: Marino Autolinee, Itabus, FlixBus
Yes, there are USB plugs on board the bus from Brindisi to Siena with the following bus company: Marino Autolinee, Itabus, FlixBus.
Yes, there is Wifi on board the bus from Brindisi to Siena with the following bus company: Marino Autolinee, Itabus, FlixBus.
popular bus stations
Popular bus stations from Brindisi to Siena
Brindisi
Siena
The major bus station for departures in Brindisi is Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale). Find all the information you need to know about services, amenities and connections at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) for your trip from Brindisi to Siena.
The major bus station for arrivals in Siena is Siena, Stazione FS (Piazzale Carlo Rosselli). Find all the information you need to know about services, amenities and connections at Siena, Stazione FS (Piazzale Carlo Rosselli) for your trip to Siena from Brindisi.
Siena, Stazione FS (Piazzale Carlo Rosselli)
information
Siena, Siena/Viale Pietro Toselli
information
Siena, P.za Gramsc
information
Most popular bus connections from Brindisi
More options for your journey from Brindisi to Siena
Here are some other resources that might have the information you need
Most popular buses to and from Siena and Brindisi
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