Brindisi to Siena bus with FlixBus

Mon, Nov 02
+ Add return
Marino Autolinee
Itabus
FlixBus
Infobus
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Marino Autolinee
Itabus
FlixBus
Infobus
Alsa
2,000+ travel companies
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The cheapest and fastest buses from Brindisi to Siena

Showing times, prices and bookable tickets for Nov 02
Cheapest price on Nov 02
€22
Average ticket price on Nov 02
€38
Fastest journey on Nov 02
11 h 15 m
Average journey duration on Nov 02
12 h 13 m
Buses on Nov 02
5
Distance
622 km
Cheap tickets

The best way to find a cheap bus ticket from Brindisi to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Brindisi to Siena will cost around €38 if you buy it on the day, but the cheapest tickets can be found for only €22.

Fast buses

On Mon, Nov 02, we found 5 buses from Brindisi to Siena, including 5 direct services.

On Mon, Nov 02 the direct buses cover the 622 km distance in an average of 12 h 13 m but if you time it right, some buses will get you there in just 11 h 15 m .

On Mon, Nov 02 the slowest buses will take 12 h 59 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Itabus
    0 transfers
  • FlixBus
    0 transfers
  • Itabus
    0 transfers
  • Itabus
    0 transfers
  • Marino Autolinee
    0 transfers

Journey information

Overview: Bus from Brindisi to Siena

ItalyItaly
ItalyItaly
Icon of bus

Buses from Brindisi to Siena run on average 11 times per day, taking around 10h 54m. Cheap bus tickets for this journey start at €9 if you book in advance.

There are 2 buses per day. The earliest bus runs at 00:05, the last at 23:39. The fastest bus covers the 386 miles (622 km) distance in 9h 44m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Plan this route

Journey facts

  • Distance386 miles (622 km)
  • Average bus duration10h 54m
  • Cheapest ticket price€9
  • Buses per day11
  • Direct buses2
  • Fastest bus9h 44m
  • First bus12:05 AM
  • Last bus11:39 PM
  • Cheapest MonthMar
  • Cheapest DayThu
  • High SeasonJul - Sep
  • Low SeasonOct - Dec
  • Busiest DayWed
  • Least Busy DayMon
  • Best time to book77 days

Understand & plan this route

Explore this journey

Book with confidence

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Frequently asked questions about your Brindisi to Siena trip

Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Brindisi to Siena.

Cheap bus tickets from Brindisi to Siena can start from as little as €9 when you book in advance. The average bus ticket price for Brindisi to Siena is €64 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Brindisi to Siena leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Brindisi to Siena leaves at 11:39 PM.
Yes, there are 2 direct buses a day from Brindisi to Siena with Marino Autolinee, Infobus. Schedules can vary on holidays or weekends with fewer direct buses.

Brindisi to Siena Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Itabus
Departure Time
03:30AM
Arrival Time
03:50PM
Duration
12h20
Departure days
Thu
Cheapest price
€54
Operator
Marino Autolinee
Departure Time
03:35AM
Arrival Time
02:50PM
Duration
11h15
Departure days
Mon
Cheapest price
€53
Operator
Itabus
Departure Time
04:30AM
Arrival Time
05:30PM
Duration
13h00
Departure days
Thu
Cheapest price
€36
Operator
Itabus
Departure Time
05:30AM
Arrival Time
05:50PM
Duration
12h20
Departure days
Sun
Cheapest price
€65
Operator
Marino Autolinee
Departure Time
05:35AM
Arrival Time
04:50PM
Duration
11h15
Departure days
Sun
Cheapest price
€55
Operator
FlixBus
Departure Time
07:55AM
Arrival Time
07:49PM
Duration
11h54
Departure days
Mon
Cheapest price
€34
Operator
Itabus
Departure Time
10:05AM
Arrival Time
11:04PM
Duration
12h59
Departure days
Mon, Wed, Thu, Sat
Cheapest price
€21
Operator
Itabus
Departure Time
11:05AM
Arrival Time
12:04AM
Duration
12h59
Departure days
Mon, Thu, Fri, Sat
Cheapest price
€28
Operator
Itabus
Departure Time
12:05PM
Arrival Time
01:04AM
Duration
12h59
Departure days
Sun
Cheapest price
€45
Operator
FlixBus
Departure Time
12:40PM
Arrival Time
12:40AM
Duration
12h00
Departure days
Sun
Cheapest price
€94
Operator
Itabus
Departure Time
04:55PM
Arrival Time
09:20AM
Duration
16h25
Departure days
Sun
Cheapest price
€43
Operator
Marino Autolinee
Departure Time
06:50PM
Arrival Time
06:45AM
Duration
11h55
Departure days
Wed, Sat
Cheapest price
€38
Operator
Marino Autolinee
Departure Time
08:50PM
Arrival Time
08:45AM
Duration
11h55
Departure days
Sun
Cheapest price
€48
Operator
Itabus
Departure Time
08:50PM
Arrival Time
08:50AM
Duration
12h00
Departure days
Mon, Fri, Sat
Cheapest price
€39
Operator
FlixBus
Departure Time
09:30PM
Arrival Time
09:15AM
Duration
11h45
Departure days
Sun
Cheapest price
€91
Operator
Itabus
Departure Time
09:50PM
Arrival Time
09:50AM
Duration
12h00
Departure days
Tue, Wed, Fri, Sat
Cheapest price
€24
Operator
Itabus
Departure Time
10:50PM
Arrival Time
10:50AM
Duration
12h00
Departure days
Sun
Cheapest price
€55
Operator
FlixBus
Departure Time
11:30PM
Arrival Time
02:50PM
Duration
15h20
Departure days
Sun
Cheapest price
€90

Live departures

Brindisi to Siena bus times

The table below shows live departures for Brindisi to Siena buses for today, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Itabus1120 · 24005:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
12h20
5:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli)1 transfer
Marino Autolinee2065:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
11h15
4:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli)0 transfersDirect
Itabus1104 · 249412:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
12h59
1:04 AM Siena, Stazione FS (Piazzale Carlo Rosselli)1 transfer
FlixBusFlixBus · FlixBus12:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
12h00
12:40 AM Siena, Stazione FS (Piazzale Carlo Rosselli)1 transfer
Itabus2214 · 11214:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
16h25
9:20 AM Siena, Stazione FS (Piazzale Carlo Rosselli)1 transfer
Marino Autolinee1078:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
11h55
8:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli)0 transfersDirect
FlixBusFlixBus · FlixBus9:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
11h45
9:15 AM Siena, Stazione FS (Piazzale Carlo Rosselli)1 transfer
Itabus1108 · 212610:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
12h00
10:50 AM Siena, Stazione FS (Piazzale Carlo Rosselli)1 transfer
FlixBusFlixBus · FlixBus · FlixBus11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
15h20
2:50 PM Siena, Siena/Viale Pietro Toselli2 transfers
FlixBusFlixBus · FlixBus11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
11h55
11:25 AM Siena, Stazione FS (Piazzale Carlo Rosselli)1 transfer

Find all the dates and times for this journey

Why should you book Brindisi to Siena buses with Omio?

Marino Autolinee as well as Itabus, FlixBus, Infobus and more offer buses services from Brindisi to Siena.
Omio is an official ticket reseller for all your travel options from Brindisi to Siena.

Why book with Omio vs Marino Autolinee?

  • Compare with other providers: On Omio, you can not only buy tickets for Marino Autolinee, but also compare tickets for the likes of Itabus, FlixBus or Infobus to find the best option for your trip from Brindisi to Siena.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Marino Autolinee with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Brindisi to Siena.

Why book with Omio over Checkmybus, Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus, FlixBus or Infobus to find the best option for your trip from Brindisi to Siena.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Brindisi to Siena.

Bus companies

Bus companies from Brindisi to Siena

Buses from Brindisi to Siena with FlixBus, Itabus, and Marino Autolinee. Overnight buses available on this route with FlixBus. Use the details below to compare onboard facilities.

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 44m
Cheapest FlixBus Price
€28
FlixBus frequency
7 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Itabus Duration
10h 35m
Cheapest Itabus Price
€14
Itabus frequency
2 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

Marino Autolinee

About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Marino Autolinee Duration
11h 15m
Cheapest Marino Autolinee Price
€9
Marino Autolinee frequency
2 a day
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

Infobus

About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Average Infobus Duration
11h 15m
Cheapest Infobus Price
€77
Infobus frequency
2 a day
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.

Companies, tickets, and onboard amenities between Brindisi and Siena

Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.

When taking a bus from Brindisi to Siena, you can count on Marino Autolinee, Itabus, FlixBus, Infobus for the best way to get you to Siena. You can also check all possible bus companies who offer a service between Brindisi and Siena and compare the amenities they offer before buying a bus ticket.
Yes, there are bathrooms on board the bus from Brindisi to Siena for bus company Marino Autolinee, Itabus, FlixBus, Infobus.
Yes, the following accessibility options are available when taking the bus from Brindisi to Siena:
  • Marino Autolinee
    • Assistance
    • Priority seating
    • Accessible restrooms.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Whether you can cancel your bus ticket from Brindisi to Siena depends on the bus companies:
  • Marino Autolinee
    • You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, there is food available to purchase on board the bus from Brindisi to Siena.
Yes, the following luggage options are included when booking a bus ticket from Brindisi to Siena:
  • Marino Autolinee
    • One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
  • Itabus
    • One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Brindisi to Siena:
  • Marino Autolinee
    • 10€ per additional bag up to 20 kg.
  • FlixBus
    • Additional luggage can be purchased for a fee.
  • Itabus
    • 5€ per additional bag.
Yes, you can bring your pet on the bus from Brindisi to Siena. The following conditions apply:
  • Marino Autolinee
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
  • Itabus
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Brindisi to Siena with the following bus company: Marino Autolinee, Itabus, FlixBus, Infobus
Yes, there are USB plugs on board the bus from Brindisi to Siena with the following bus company: Marino Autolinee, Itabus, FlixBus, Infobus.
Yes, there is Wifi on board the bus from Brindisi to Siena with the following bus company: Marino Autolinee, Itabus, FlixBus, Infobus.

Complete guide to Siena

Things to do in Siena

Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.

  • Must visit

Museo Civico

Siena’s main civic museum displays Lorenzetti’s frescoes and superb medieval art inside the historic town hall. It is essential for understanding the city.

  • Must visit

Santa Maria della Scala

This major museum complex occupies a former hospital and combines archaeology, frescoes, chapels, and underground spaces in a memorable setting.

  • Must visit

Museo dell'Opera del Duomo

The cathedral museum preserves sculptures, stained glass, and treasures from the Duomo complex, including close views of masterpieces and architecture.

Euro (€)

Moderate for Italy: lodging and dining cost more than small towns, but transit is limited and many sights are walkable.

Average meal costs

Budget
€8-15 for pizza slices, panini, or casual lunch.
Mid-range
€20-35 per person for a restaurant meal.
Fine dining
€60+ per person for upscale dining.
Coffee
€1.30-3 for espresso or cappuccino.

Tipping culture

Service is often included or covered by coperto. Round up or leave 5-10% for great restaurant service; taxis are usually rounded up; cafés need no tip.

Plan your visit to Siena

Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Siena.

Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Siena, travelers should be cautious of pickpocketing, especially in crowded areas like Piazza del Campo and on public transportation. Common scams include overpriced taxi rides and unofficial ticket sellers near popular attractions. Staying aware of surroundings and using authorized services helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

FAQs: Bus from Brindisi to Siena

Find answers to the most common questions about traveling from Brindisi to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

FAQs
It's helpful to compare your options as there are 3 ways to travel between Brindisi and Siena including taking a bus, train, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.

popular bus stations

Popular bus stations from Brindisi to Siena

Most Brindisi to Siena buses use the Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) to Siena, Stazione FS (Piazzale Carlo Rosselli) station pair, with some services arriving at Siena, Siena/Viale Pietro Toselli. Use this guide to compare Brindisi and Siena bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Brindisi
Arrival bus stations in Siena
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)Brindisi Falcone Professional Institute, Via Giuseppe Maria Galanti 8, 72100
BrindisiBrindisi BUS, 72100 Brindisi BR, ItalyWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Brindisi from Brindisi city centre

TRUE

Brindisi bus station facilities and services

Brindisi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Cafes and small eateries nearby.

Wi-Fi and ATMs

Wi-Fi is available at Brindisi. ATMs are available at Brindisi.

Tickets and information

Ticket office support is available at Brindisi.

Parking, taxis and toilets

Available at Brindisi: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Brindisi: Wheelchair ramps available.

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We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

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