- Must visit
Museo Civico di Siena
The city museum inside Palazzo Pubblico, best known for Ambrogio Lorenzetti’s fresco cycle Allegory of Good and Bad Government. Essential for understanding Siena’s civic history and medieval art.
Cheapest price
$18
Average price
$34
Fastest journey
5 h 15 m
Average duration
6 h 5 m
Buses per day
5
Distance
253 km
The best way to find a cheap bus ticket from Pescara to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pescara to Siena will cost around $34 if you buy it on the day, but the cheapest tickets can be found for only $18.
Of the 5 buses that leave Pescara for Siena on Thu, Jun 25, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jun 25 the direct buses cover the 253 km distance in an average of 6 h 5 m but if you time it right, some buses will get you there in just 5 h 15 m .
On Thu, Jun 25 the slowest buses will take 7 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Omio recommends booking the bus as it is the most popular option from Pescara to Siena among Omio's users. If you are prioritising price take the bus with prices starting from $18. For those with little time consider booking a bus which can get you there in 5h 5m. The ticket price range depends on the travel mode: a bus costs an average of $18, and a train costs an average of $39.
Distance: 157 miles (253 km)
Most popular Bus | Train | Driving |
|---|---|---|
$33 Average price Cheapest | $44 Average price | $80 Average price (fuel + tolls) |
5h 35m Average total duration Fastest 5h 5m Onboard + 30m Additional time* | 6h 49m Average total duration 6h 19m Onboard + 30m Additional time* | 3h 59m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pescara to Siena:
A bus is $11 (€9) less than a train for this route with tickets for a train from Pescara to Siena costing on average $44 (€36).
Other travel options to Siena take longer:
Train takes on average 6h 19m.
Tickets start at around $33 (€27) compared to roughly $80 (€66) in fuel and tolls — a saving of about $47 (€39). The journey takes 5h 5m versus 3h 59m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:15AM | Arrival Time 09:25AM | Duration 7h10 | Departure days Thu, Fri, Sun | Cheapest price $33 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 10:25AM | Duration 7h10 | Departure days Fri | Cheapest price $26 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 09:35AM | Duration 5h15 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 10:35AM | Duration 5h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $19 |
Operator FlixBus | Departure Time 08:35AM | Arrival Time 02:54PM | Duration 6h19 | Departure days Mon | Cheapest price $41 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 04:00PM | Duration 6h30 | Departure days Mon, Wed, Thu | Cheapest price $18 |
Operator FlixBus | Departure Time 09:50AM | Arrival Time 04:05PM | Duration 6h15 | Departure days Mon, Wed, Fri, Sat | Cheapest price $24 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 03:55PM | Duration 6h00 | Departure days Tue | Cheapest price $28 |
Operator FlixBus | Departure Time 10:50AM | Arrival Time 05:05PM | Duration 6h15 | Departure days Mon, Tue, Thu, Sat | Cheapest price $22 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 11:40PM | Duration 6h35 | Departure days Mon | Cheapest price $48 |
The table below shows live departures for Pescara to Siena buses for today, Wednesday, June 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:50 AM Pescara | 6h15 | 4:05 PM Siena | 0 transfersDirect | |
| Thursday, June 25 | |||||
![]() | 2:15 AM Pescara | 7h10 | 9:25 AM Siena | 0 transfersDirect | |
![]() | 4:20 AM Pescara | 5h15 | 9:35 AM Siena | 0 transfersDirect | |
![]() | 5:20 AM Pescara | 5h15 | 10:35 AM Siena | 0 transfersDirect | |
![]() | 9:30 AM Pescara | 6h30 | 4:00 PM Siena | 0 transfersDirect | |
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pescara to Siena run on average 8 times per day, taking around 5h 5m. Cheap bus tickets for this journey start at $18 (€15) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:45, the last at 23:39. The fastest bus covers the 157 miles (253 km) distance in 5h 15m.
Distance 157 miles (253 km) |
Average bus duration 5h 5m |
Cheapest ticket price $18 (€15) |
Buses per day 8 |
Direct buses 3 |
Fastest bus 5h 15m |
First bus 12:45 AM |
Last bus 11:39 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Thu |
Least Busy Day Tue |
Best time to book 35 days |
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
The city museum inside Palazzo Pubblico, best known for Ambrogio Lorenzetti’s fresco cycle Allegory of Good and Bad Government. Essential for understanding Siena’s civic history and medieval art.
A vast former hospital turned museum complex with archaeological collections, frescoed halls, and major temporary exhibitions. One of Siena’s richest cultural sites and a local favorite beyond the Duo
The cathedral museum preserves original sculptures, stained glass, and masterpieces linked to Siena Cathedral. It is part of the Duomo complex and one of the city’s most rewarding art visits.
Siena’s shell-shaped main square is one of Italy’s greatest urban spaces and the home of the Palio. It is the city’s social heart and the first place most visitors should experience.
The cathedral square concentrates some of Siena’s most important monuments and dramatic architectural views. It is one of the city’s most photogenic areas.
One of Siena’s most elegant historic streets, lined with noble buildings, shops, and architectural details. It is ideal for slow walking between major sights.
Thick hand-rolled Tuscan pasta served with a garlicky tomato sauce made with aglione, a traditional local garlic variety.
A rustic Tuscan bread and tomato soup with olive oil and basil, closely associated with the Siena area and home cooking traditions.
A hearty Tuscan vegetable and bread soup, often made with beans and cavolo nero, traditional in Siena and across Tuscany.
Well-known traditional restaurant in a historic cellar setting, famous for Tuscan classics, pici, and warm atmospheric dining.
Established refined osteria near Piazza del Campo, known for elegant Tuscan cuisine, seasonal ingredients, and a polished intimate atmosphere.
Historic casual trattoria close to Piazza del Campo, appreciated for hearty Sienese dishes, generous portions, and classic local character.
Moderate by Italian standards. Cafes and simple meals are affordable, while tourist-center dining and hotels cost more.
Service is often included or covered by a coperto. Tipping is not required, but leaving EUR 1-2 at cafes or 5-10% for great restaurant service is appreciated. Round up taxis.
Official public transport app
Siena Stazione FS, Piazzale Carlo Rosselli, Siena -> Piazza del Campo, Siena
Find answers to the most common questions about traveling from Pescara to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

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