- Must visit
Pinacoteca di Brera
Milan’s premier art gallery, known for Italian masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$9
Average price
$31
Fastest journey
4 h 55 m
Average duration
5 h 37 m
Buses per day
12
Distance
293 km
The best way to find a cheap bus ticket from Siena to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Milan will cost around $31 if you buy it on the day, but the cheapest tickets can be found for only $9.
Of the 12 buses that leave Siena for Milan on Wed, Jun 10, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jun 10 the direct buses cover the 293 km distance in an average of 5 h 37 m but if you time it right, some buses will get you there in just 4 h 55 m .
On Wed, Jun 10 the slowest buses will take 5 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2126
2402
FlixBus
FlixBus
FlixBus
2402
FlixBus
2126
FlixBus
FlixBusOmio recommends booking the bus as it is the most popular option from Siena to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $9. For those with little time consider booking a train which can get you there in 4h 1m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $9, and a train costs an average of $34.
Distance: 182 miles (293 km)
Most popular Bus | Train |
|---|---|
$17 Average price Cheapest | $46 Average price |
6h 20m Average total duration 5h 50m Onboard + 30m Additional time* | 4h 31m Average total duration Fastest 4h 1m Onboard + 30m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Siena to Milan:
A bus is $29 (€23) less than a train for this route with tickets for a train from Siena to Milan costing on average $46 (€37).
Other travel options to Milan take longer:
Bus takes on average 5h 50m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 05:55AM | Duration 5h10 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $14 |
Operator Itabus | Departure Time 01:05AM | Arrival Time 06:55AM | Duration 5h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 01:20AM | Arrival Time 04:40AM | Duration 3h20 | Departure days Mon | Cheapest price $35 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 01:00PM | Duration 6h50 | Departure days Everyday | Cheapest price $14 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 11:45AM | Duration 5h15 | Departure days Tue | Cheapest price $15 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 11:30AM | Duration 4h50 | Departure days Mon, Fri, Sat, Sun | Cheapest price $14 |
Operator FlixBus | Departure Time 07:50AM | Arrival Time 01:45PM | Duration 5h55 | Departure days Everyday | Cheapest price $14 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 02:35PM | Duration 5h15 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 09:40AM | Arrival Time 01:20PM | Duration 3h40 | Departure days Wed | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 10:20AM | Arrival Time 02:10PM | Duration 3h50 | Departure days Sat | Cheapest price $44 |
Operator Itabus | Departure Time 10:55AM | Arrival Time 04:40PM | Duration 5h45 | Departure days Everyday | Cheapest price $9 |
Operator BlaBlaCar | Departure Time 11:20AM | Arrival Time 03:50PM | Duration 4h30 | Departure days Thu | Cheapest price $25 |
Operator FlixBus | Departure Time 11:30AM | Arrival Time 06:55PM | Duration 7h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $28 |
Operator FlixBus | Departure Time 11:40AM | Arrival Time 06:30PM | Duration 6h50 | Departure days Mon, Wed | Cheapest price $49 |
Operator BlaBlaCar | Departure Time 11:50AM | Arrival Time 03:10PM | Duration 3h20 | Departure days Fri | Cheapest price $28 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 05:55PM | Duration 5h40 | Departure days Everyday | Cheapest price $25 |
Operator Itabus | Departure Time 01:55PM | Arrival Time 06:50PM | Duration 4h55 | Departure days Everyday | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 02:10PM | Arrival Time 06:10PM | Duration 4h00 | Departure days Fri | Cheapest price $35 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 09:45PM | Duration 7h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $26 |
Operator FlixBus | Departure Time 02:51PM | Arrival Time 09:40PM | Duration 6h49 | Departure days Everyday | Cheapest price $26 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 06:40PM | Duration 3h40 | Departure days Wed | Cheapest price $31 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 09:40PM | Duration 6h35 | Departure days Everyday | Cheapest price $26 |
Operator BlaBlaCar | Departure Time 03:40PM | Arrival Time 07:00PM | Duration 3h20 | Departure days Mon, Fri | Cheapest price $34 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 07:30PM | Duration 3h30 | Departure days Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 08:55PM | Duration 4h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $26 |
Operator BlaBlaCar | Departure Time 04:10PM | Arrival Time 09:10PM | Duration 5h00 | Departure days Tue | Cheapest price $33 |
Operator BlaBlaCar | Departure Time 04:50PM | Arrival Time 08:20PM | Duration 3h30 | Departure days Wed | Cheapest price $29 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 11:35PM | Duration 6h10 | Departure days Mon, Fri, Sat, Sun | Cheapest price $14 |
Operator Itabus | Departure Time 05:55PM | Arrival Time 11:05PM | Duration 5h10 | Departure days Thu, Fri, Sat, Sun | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 09:20PM | Duration 3h20 | Departure days Wed, Sun | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 06:20PM | Arrival Time 10:00PM | Duration 3h40 | Departure days Wed | Cheapest price $32 |
Operator FlixBus | Departure Time 06:40PM | Arrival Time 11:59PM | Duration 5h19 | Departure days Thu, Fri, Sat, Sun | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 06:50PM | Arrival Time 10:40PM | Duration 3h50 | Departure days Mon | Cheapest price $35 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 04:00AM | Duration 7h35 | Departure days Wed | Cheapest price $40 |
Operator BlaBlaCar | Departure Time 10:00PM | Arrival Time 02:10AM | Duration 4h10 | Departure days Sun | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 11:40PM | Arrival Time 03:40AM | Duration 4h00 | Departure days Sat | Cheapest price $46 |
The table below shows live departures for Siena to Milan buses for tomorrow, Wednesday, June 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 6:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h50 | 12:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 6:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h50 | 1:00 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 7:50 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h55 | 1:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 7:50 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h45 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
2126 | 10:55 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h45 | 4:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 11:40 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h50 | 6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 12:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h40 | 5:55 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 12:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 7h45 | 8:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
2402 | 1:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 4h55 | 6:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 2:51 PM Siena, Siena/Viale Pietro Toselli | 6h49 | 9:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 3:05 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h35 | 9:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Siena to Milan run on average 24 times per day, taking around 5h 50m. Cheap bus tickets for this journey start at $9 (€7) if you book in advance.
There are 18 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 182 miles (293 km) distance in 4h 50m.
Distance 182 miles (293 km) |
Average bus duration 5h 50m |
Cheapest ticket price $9 (€7) |
Buses per day 24 |
Direct buses 18 |
Fastest bus 4h 50m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 56 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
Milan’s premier art gallery, known for Italian masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Museum entry for Leonardo’s The Last Supper, one of the world’s most famous artworks and a priority booking site in Milan.
Major museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist collections and rooftop views.
Milan’s canal district, known for waterside walks, lively atmosphere, and highly photogenic bridges and reflections.
Charming central neighborhood with elegant streets, galleries, boutiques, and a classic Milanese artistic atmosphere.
Milan’s main square and the city’s most important urban landmark, ideal for first-time visitors and classic views.
Milan’s signature saffron risotto, rich with butter and cheese, prized for its golden color and elegant flavor.
A traditional breaded veal cutlet, fried until crisp. It is one of the city’s most iconic and historic main dishes.
Braised veal shank, often served with risotto alla Milanese. It is a classic Lombard comfort dish with deep, slow-cooked flavor.
Iconic casual spot famous for panzerotti, beloved by locals and visitors for quick, affordable bites near the Duomo.
Well-known modern Milanese restaurant celebrated for refined local dishes such as mondeghili and risotto in a stylish setting.
Historic traditional trattoria serving classic Milanese and Lombard dishes in an old-world, elegant atmosphere.
Prices are high by Italian standards, especially for hotels and central dining, but budget cafés and aperitivo deals help control daily costs.
Tipping is modest. Service may be included or a coperto charged. Round up or leave 5-10% for very good restaurant service; small change for taxis and cafés is enough.
Official public transport app
Milano Linate Airport, Milan -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Siena to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

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