- Must visit
Pinacoteca di Brera
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
Cheapest price
$13
Average price
$22
Fastest journey
4 h 30 m
Average duration
4 h 51 m
Buses per day
21
Distance
293 km
The best way to find a cheap bus ticket from Siena to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Milan will cost around $22 if you buy it on the day, but the cheapest tickets can be found for only $13.
Of the 21 buses that leave Siena for Milan on Sun, Jul 26, 19 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jul 26 the direct buses cover the 293 km distance in an average of 4 h 51 m but if you time it right, some buses will get you there in just 4 h 30 m .
On Sun, Jul 26 the slowest buses will take 5 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
2402
FlixBusOmio recommends booking the bus as it is the most popular option from Siena to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $7. For those with little time consider booking a train which can get you there in 4h 1m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $7, and a train costs an average of $27.
Distance: 182 miles (293 km)
Most popular Bus | Train |
|---|---|
$14 Average price Cheapest | $37 Average price |
6h 20m Average total duration 5h 50m Onboard + 30m Additional time* | 4h 31m Average total duration Fastest 4h 1m Onboard + 30m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Siena to Milan:
A bus is $23 (€23) less than a train for this route with tickets for a train from Siena to Milan costing on average $37 (€37).
Other travel options to Milan take longer:
Bus takes on average 5h 50m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 05:55AM | Duration 5h10 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $16 |
Operator Itabus | Departure Time 01:05AM | Arrival Time 06:55AM | Duration 5h50 | Departure days Mon, Thu, Fri, Sun | Cheapest price $15 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 12:00PM | Duration 5h50 | Departure days Everyday | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 06:20AM | Arrival Time 09:40AM | Duration 3h20 | Departure days Mon | Cheapest price $32 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 11:45AM | Duration 5h15 | Departure days Tue | Cheapest price $12 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 11:30AM | Duration 4h50 | Departure days Mon, Fri, Sat, Sun | Cheapest price $7 |
Operator BlaBlaCar | Departure Time 07:20AM | Arrival Time 11:20AM | Duration 4h00 | Departure days Thu, Sat | Cheapest price $29 |
Operator FlixBus | Departure Time 07:50AM | Arrival Time 01:45PM | Duration 5h55 | Departure days Everyday | Cheapest price $7 |
Operator BlaBlaCar | Departure Time 08:40AM | Arrival Time 12:00PM | Duration 3h20 | Departure days Wed | Cheapest price $33 |
Operator BlaBlaCar | Departure Time 09:10AM | Arrival Time 01:20PM | Duration 4h10 | Departure days Mon | Cheapest price $25 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 03:20PM | Duration 6h00 | Departure days Mon, Tue, Thu, Fri, Sun | Cheapest price $7 |
Operator BlaBlaCar | Departure Time 09:50AM | Arrival Time 01:10PM | Duration 3h20 | Departure days Wed | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 03:00PM | Duration 5h00 | Departure days Sat | Cheapest price $27 |
Operator Itabus | Departure Time 10:55AM | Arrival Time 04:40PM | Duration 5h45 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $9 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 02:30PM | Duration 3h30 | Departure days Mon, Wed | Cheapest price $27 |
Operator FlixBus | Departure Time 11:30AM | Arrival Time 06:55PM | Duration 7h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $15 |
Operator FlixBus | Departure Time 11:40AM | Arrival Time 06:30PM | Duration 6h50 | Departure days Sat | Cheapest price $52 |
Operator BlaBlaCar | Departure Time 12:10PM | Arrival Time 03:40PM | Duration 3h30 | Departure days Tue | Cheapest price $21 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 05:55PM | Duration 5h40 | Departure days Everyday | Cheapest price $19 |
Operator BlaBlaCar | Departure Time 12:40PM | Arrival Time 05:00PM | Duration 4h20 | Departure days Sun | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 12:50PM | Arrival Time 05:10PM | Duration 4h20 | Departure days Sat | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 01:00PM | Arrival Time 05:00PM | Duration 4h00 | Departure days Wed | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 01:20PM | Arrival Time 05:10PM | Duration 3h50 | Departure days Sun | Cheapest price $24 |
Operator Itabus | Departure Time 01:55PM | Arrival Time 06:50PM | Duration 4h55 | Departure days Everyday | Cheapest price $17 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 09:45PM | Duration 7h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $13 |
Operator FlixBus | Departure Time 02:51PM | Arrival Time 09:40PM | Duration 6h49 | Departure days Everyday | Cheapest price $10 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 07:00PM | Duration 4h00 | Departure days Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 09:40PM | Duration 6h35 | Departure days Everyday | Cheapest price $10 |
Operator BlaBlaCar | Departure Time 03:30PM | Arrival Time 07:20PM | Duration 3h50 | Departure days Sat | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 07:30PM | Duration 3h30 | Departure days Sun | Cheapest price $27 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 08:55PM | Duration 4h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $10 |
Operator BlaBlaCar | Departure Time 05:10PM | Arrival Time 08:30PM | Duration 3h20 | Departure days Mon | Cheapest price $25 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 11:35PM | Duration 6h10 | Departure days Mon, Fri, Sat, Sun | Cheapest price $10 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 09:40PM | Duration 3h40 | Departure days Mon | Cheapest price $25 |
Operator FlixBus | Departure Time 06:40PM | Arrival Time 11:59PM | Duration 5h19 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $7 |
Operator BlaBlaCar | Departure Time 10:00PM | Arrival Time 01:30AM | Duration 3h30 | Departure days Sun | Cheapest price $25 |
Operator BlaBlaCar | Departure Time 11:30PM | Arrival Time 03:20AM | Duration 3h50 | Departure days Wed | Cheapest price $27 |
The table below shows live departures for Siena to Milan buses for today, Saturday, July 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 11:30 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 7h25 | 6:55 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 11:40 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h50 | 6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 12:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h40 | 5:55 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
2402 | 1:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 4h55 | 6:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 2:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 7h20 | 9:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 2:51 PM Siena, Siena/Viale Pietro Toselli | 6h49 | 9:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 2:51 PM Siena, Siena/Viale Pietro Toselli | 6h04 | 8:55 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 3:05 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h35 | 9:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 4:05 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 4h50 | 8:55 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 5:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h10 | 11:35 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 5:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h35 | 11:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 6:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h19 | 11:59 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
| Sunday, July 26 | |||||
FlixBus | 12:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h10 | 5:55 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 12:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 4h30 | 5:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
2494 | 1:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h50 | 6:55 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h50 | 1:00 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h50 | 12:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 6:40 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 4h50 | 11:30 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 7:50 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h55 | 1:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 9:20 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h00 | 3:20 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 9:20 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h15 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Siena to Milan run on average 24 times per day, taking around 5h 50m. Cheap bus tickets for this journey start at $7 (€7) if you book in advance.
There are 18 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 182 miles (293 km) distance in 4h 50m.
Distance 182 miles (293 km) |
Average bus duration 5h 50m |
Cheapest ticket price $7 (€7) |
Buses per day 24 |
Direct buses 18 |
Fastest bus 4h 50m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 56 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
This contemporary art museum near Porta Romana presents rotating exhibitions in a striking former industrial distillery complex.
Italy’s leading science museum is set in a former monastery and features Leonardo galleries, trains, aircraft, and a submarine.
Milan’s central square frames the cathedral and major civic buildings, making it the city’s essential meeting point and photo stop.
This artistic district offers charming lanes, Brera atmosphere, boutiques, and easy access to galleries and evening strolls.
A large landscaped park behind the castle, perfect for walks, skyline views, and reaching landmarks like the Arch of Peace.
Saffron risotto cooked with butter, stock and cheese. It is Milan's signature dish, linked to the city's love of rich northern Italian rice cookery.
Breaded veal cutlet fried in butter until golden. A classic Milanese main, prized for its simple preparation and long-standing local tradition.
Slow-braised veal shanks with vegetables, wine and broth, often finished with gremolata. A hearty Lombard specialty commonly paired with risotto.
Three-Michelin-star fine dining by Enrico Bartolini in MUDEC. Expect refined Italian tasting menus in a polished contemporary setting.
Historic Milanese restaurant near the Duomo, famous for risotto and cotoletta. Traditional, elegant rooms and a strong local culinary identity.
Long-running local favorite for classic Milanese cuisine, especially risotto and ossobuco. Warm, old-school atmosphere in the Brera area.
Moderate for Western Europe. Hotels and central dining can be pricey, but transit is affordable and budget meals, aperitivo deals, and local cafes help keep daily costs reasonable.
Tipping is modest. Service may be included. Round up or leave €1-2 at cafes, 5-10% for good restaurant service, and round up taxi fares.
Official public transport app
Orio al Serio, Milan Bergamo Airport (Bus station) -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Siena to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Most Siena to Milan buses use the Siena, Stazione FS (Piazzale Carlo Rosselli) to Milano, Autostazione Lampugnano station pair, with some services arriving at Milano, San Donato - Settore B (Viale Giuseppe Impastato). Use this guide to compare Siena and Milan bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Here are some other resources that might have the information you need