- Must visit
Museo Civico di Siena
The city museum inside Palazzo Pubblico, best known for Ambrogio Lorenzetti’s frescoes including the Allegory of Good and Bad Government.
Cheapest price
$50
Average price
$82
Fastest journey
9 h 10 m
Average duration
10 h 6 m
Buses per day
11
Distance
526 km
The best way to find a cheap bus ticket from Matera to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Matera to Siena will cost around $82 if you buy it on the day, but the cheapest tickets can be found for only $50.
It's difficult to get from Matera to Siena without transferring at least once.
2214 · 1121
3826 · 1121
1202 · 1104 · 2494
1202 · 1402 · 2494
202 · 206
132 · 107
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
202 · 206Omio recommends booking the bus as it is the most popular option from Matera to Siena among Omio's users. If you are prioritising price take the bus with prices starting from $25. For those with little time consider booking a flight which can get you there in 1h 25m. The ticket price range depends on the travel mode: a bus costs an average of $25, and a train costs an average of $94.
Distance: 326 miles (526 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$48 Average price Cheapest | $59 Average price | $137 Average price | $178 Average price (fuel + tolls) |
10h 20m Average total duration 9h 50m Onboard + 30m Additional time* | 4h 25m Average total duration Fastest 1h 25m Onboard + 3h 0m Additional time* | 9h 41m Average total duration 9h 11m Onboard + 30m Additional time* | 6h 36m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Matera to Siena:
A bus is $10 (€8) less than a flight for this route with tickets for a flight from Matera to Siena costing on average $59 (€47).
A bus is $88 (€71) less than a train for this route with tickets for a train from Matera to Siena costing on average $137 (€110).
Other travel options to Siena take longer:
Train takes on average 9h 11m.
Bus takes on average 9h 50m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:35AM | Arrival Time 02:50PM | Duration 14h15 | Departure days Tue, Wed, Sun | Cheapest price $91 |
Operator Marino Autolinee | Departure Time 04:15AM | Arrival Time 02:50PM | Duration 10h35 | Departure days Mon, Thu | Cheapest price $51 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 09:49PM | Duration 15h44 | Departure days Tue | Cheapest price $135 |
Operator Marino Autolinee | Departure Time 06:15AM | Arrival Time 04:50PM | Duration 10h35 | Departure days Tue, Wed, Sun | Cheapest price $82 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 03:50PM | Duration 6h50 | Departure days Tue | Cheapest price $52 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 11:40PM | Duration 12h45 | Departure days Thu | Cheapest price $30 |
Operator Itabus | Departure Time 10:55AM | Arrival Time 01:04AM | Duration 14h09 | Departure days Wed, Sat, Sun | Cheapest price $53 |
Operator FlixBus | Departure Time 11:30AM | Arrival Time 09:49PM | Duration 10h19 | Departure days Tue, Wed, Sat, Sun | Cheapest price $76 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 04:05AM | Duration 14h25 | Departure days Fri | Cheapest price $49 |
Operator Itabus | Departure Time 02:00PM | Arrival Time 07:20AM | Duration 17h20 | Departure days Thu, Fri | Cheapest price $51 |
Operator FlixBus | Departure Time 02:55PM | Arrival Time 05:05AM | Duration 14h10 | Departure days Mon, Thu, Fri | Cheapest price $25 |
Operator Itabus | Departure Time 03:00PM | Arrival Time 08:20AM | Duration 17h20 | Departure days Fri | Cheapest price $58 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 06:05AM | Duration 14h25 | Departure days Tue, Wed, Sat, Sun | Cheapest price $78 |
Operator Itabus | Departure Time 04:00PM | Arrival Time 09:20AM | Duration 17h20 | Departure days Sat, Sun | Cheapest price $56 |
Operator Itabus | Departure Time 05:15PM | Arrival Time 07:20AM | Duration 14h05 | Departure days Mon, Thu, Fri | Cheapest price $51 |
Operator Itabus | Departure Time 07:15PM | Arrival Time 09:20AM | Duration 14h05 | Departure days Tue, Wed, Sat, Sun | Cheapest price $45 |
Operator Marino Autolinee | Departure Time 11:35PM | Arrival Time 08:45AM | Duration 9h10 | Departure days Tue, Wed, Sat, Sun | Cheapest price $99 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 10:25AM | Duration 10h50 | Departure days Thu | Cheapest price $41 |
The table below shows live departures for Matera to Siena buses for today, Saturday, May 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 3:40 PM Matera, Terminal Bus Via Don Luigi Sturzo | 14h25 | 6:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
3826 · 1121 | 4:00 PM Matera, Terminal Bus Via Don Luigi Sturzo | 17h20 | 9:20 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
2214 · 1121 | 7:15 PM Matera, Terminal Bus Via Don Luigi Sturzo | 14h05 | 9:20 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
132 · 107 | 11:35 PM Matera, Terminal Bus Via Don Luigi Sturzo | 9h10 | 8:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
| Sunday, May 31 | |||||
FlixBus · FlixBus | 12:35 AM Matera, Terminal Bus Via Don Luigi Sturzo | 14h15 | 2:50 PM Siena, Siena/Viale Pietro Toselli | 1 transfer | |
FlixBus · FlixBus | 12:35 AM Matera, Terminal Bus Via Don Luigi Sturzo | 10h00 | 10:35 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
202 · 206 | 6:15 AM Matera, Terminal Bus Via Don Luigi Sturzo | 10h35 | 4:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
1202 · 1402 · 2494 | 10:55 AM Matera, Terminal Bus Via Don Luigi Sturzo | 14h09 | 1:04 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 2 transfers | |
1202 · 1104 · 2494 | 10:55 AM Matera, Terminal Bus Via Don Luigi Sturzo | 14h09 | 1:04 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 2 transfers | |
FlixBus · FlixBus | 11:30 AM Matera, Terminal Bus Via Don Luigi Sturzo | 10h19 | 9:49 PM Siena, Siena/Viale Pietro Toselli | 1 transfer | |
FlixBus · FlixBus | 11:30 AM Matera, Terminal Bus Via Don Luigi Sturzo | 10h25 | 9:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Matera to Siena run on average 10 times per day, taking around 9h 50m. Cheap bus tickets for this journey start at $25 (€20) but you can travel from only $21 (€17) by flight.
There are 1 buses per day. The earliest bus runs at 00:30, the last at 23:50. The fastest bus covers the 326 miles (526 km) distance in 10h 35m.
Distance 326 miles (526 km) |
Average bus duration 9h 50m |
Cheapest ticket price $25 (€20) |
Buses per day 10 |
Direct buses 1 |
Fastest bus 10h 35m |
First bus 12:30 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 42 days |
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
The city museum inside Palazzo Pubblico, best known for Ambrogio Lorenzetti’s frescoes including the Allegory of Good and Bad Government.
A major museum complex in a former hospital opposite the cathedral, with archaeological collections, frescoed halls, and temporary exhibitions.
Cathedral museum displaying sculpture, stained glass, and masterpieces connected to Siena Cathedral, including works by Duccio and Pisano.
Siena’s shell-shaped main square, world famous for the Palio and one of Italy’s greatest urban spaces.
The UNESCO-listed historic center, best explored on foot for its lanes, brick facades, and preserved medieval atmosphere.
One of the most popular viewpoints in Siena, widely shared on social media for its rooftops, tower views, and Tuscan backdrop.
Thick handmade Tuscan pasta served with a garlicky tomato sauce made with aglione, a mild local garlic. A classic Sienese dish found in trattorie across the city.
Pici tossed with olive oil, garlic, and toasted breadcrumbs. It is a simple, traditional poor-cuisine dish strongly associated with Siena and southern Tuscany.
A hearty Tuscan soup of bread, cannellini beans, and vegetables, especially black cabbage. It is a rustic staple of the region and commonly served in Siena.
Well-known restaurant in a vaulted historic space, popular for Tuscan specialties, quality wines, and polished but welcoming service.
Long-established upscale restaurant blending Tuscan tradition with refined technique. Known for seasonal ingredients, an elegant room, and a strong wine list.
Established dining spot set in evocative medieval rooms, serving Tuscan cuisine with a more refined touch and a memorable atmosphere.
Moderate by Italian standards. Cafes and simple meals are reasonable; central hotels and tourist restaurants cost more.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving 5-10% for good service is appreciated. Small change for cafes and taxis is enough.
Official public transport app
Siena Stazione FS, Piazzale Carlo Rosselli, Siena -> Piazza del Campo, Siena
Siena is worth visiting if you’re a foodie, wine_lover, history buff, or interested in medieval architecture. Right in the heart of Tuscany, this city is a popular tourist destination, and a visit here will show you why. The city is easily accessible by bus, and from Matera, about 326 miles (525 km) away, the trip takes about 10h 40mins on the fastest bus. Two companies offer the buses from Matera to Siena, and you can book either bus using the Omio app on your phone.
At least nine buses depart from Matera to Siena every day. These are provided by the two main bus providers on this route, FlixBus and MarinoBus. The departures begin from early morning till late evening, and there are night buses available on this trip. The first bus to leave for Siena usually departs the station at around 12:25 a.m., while the last bus starts its trip at around 10:00 p.m. Download the Omio app to see the bus schedule for buses for Matera to Siena conveniently on your phone.
The journey from Matera to Siena is long, but you’ll have two bus providers ready to ferry you there. The two cities are about 326 miles (525 km) apart, and the fastest bus takes about 10h 40min to make this trip. MarinoBus and FlixBus are the two main providers for buses from Matera to Siena, and both companies only provide one_stop buses for this trip. The buses can take anywhere from 10h 40min on this trip, to as much as 17h 45min, depending on their stopover. Download the Omio app to see the various journeys and the duration of each journey.

Matera Night Sky. Source: Shutterstock
Departure bus station: Via Don Luigi Sturzo is the main departure station, and it’s about 1.1 miles (1.8 km) from the city center. The public bus is the best way of getting to and from the station, with bus lines 2, 7, and 15 serving this station. The station is wheelchair accessible, and some station amenities include ticket offices and covered waiting benches.
Arrival bus station: Stazione FS is about 2.5 miles (4 km from downtown Siena. You can get downtown by bus or taxi, but part of the journey includes a walk since no cars or buses can access the city center. The station is wheelchair accessible, and you’ll find clean restrooms, ticket offices, waiting benches at the station. Also, there are several shops and restaurants next to the station.
FlixBus and MarinoBus are the leading bus providers on this route. FlixBus is the main provider, with at least seven departures every day. MarinoBus is also available daily, but they only have two buses making this trip. Both companies only provide connecting services between Matera and Siena, and some of the most common stops include Cerignola, Milan, Naples, and Rome. FlixBus is the better option since they provide the fastest bus, are cheapest, and have several departures throughout the day compared to the morning and night buses from MarinoBus. Nonetheless, both companies provide comfortable travel conditions, and you can read more about them on the Omio magazine, Window Seat.
Flixbus is the main provider for buses from Matera to Siena. The company has at least seven daily departures, and on high_demand days, you can find up to 13 buses making this trip. All buses provided include a stopover en route, and some of the most common stops are in Rome, Naples, and Milan. The fastest FlixBus making this trip takes about 10h 40min, while the slowest takes about 17h 45min, and includes a stopover in Milan, up north. FlixBus buses are also affordable and would be the best option if you’re traveling on a budget.
MarinoBus is the second_best option if you’re traveling from Matera to Siena by bus. MarinoBus has at least two daily departures, a morning and night bus to Siena. Both buses have a stopover in Cerignola en route to Siena. Their fastest bus on this trip takes about 10h 40min and would be a good option if you wish to get to Siena pronto. MarinoBus buses are comfortable and offer great travel conditions.
For those looking to travel sustainably from Matera to Siena, consider booking your bus ticket using the Omio app for a sustainable trip. Buses are a sustainable mode of transport, and here is why. First, buses travel less frequently than single_occupancy vehicles (SOVs), meaning they cause less carbon and noise pollution. Buses also transport many passengers at once, a good thing since this means fewer emissions per passenger. Moreover, on the roads, they cause less congestion, preventing emissions from stationary vehicles. Finally, bus providers now have carbon offsetting programs where passengers can compensate for the carbon they emit on this trip.
This bus only has one fare _ standard seat. Each passenger will be allowed two bags on FlixBus buses. Bikes can travel on the bus for an extra fee. The buses are equipped with wheelchair lifts, and drivers will assist disabled passengers needing extra assistance. Pets are not welcome on the bus, and onboard amenities include recliner seats with extra legroom, air conditioning, free Wi_Fi, power plugs, clean restrooms, and onboard entertainment.
This bus only offers the standard seat, and passengers will be allowed to bring two bags on this journey. Bikes can travel under the bus for an extra charge, but wheelchairs travel for free. The buses have wheelchair lifts, and the drivers will assist all disabled passengers needing any assistance. Pets can travel in pet carriers on board. Amenities offered include reclining seats with extra legroom, free Wi_Fi, clean restrooms, air conditioning, onboard entertainment, and AC outlets.
Here are four hacks you can use to get cheap Matera to Siena bus tickets. The first hack is to book your ticket in advance. Booking several weeks or months in advance gives you a better chance of getting cheap tickets than booking during the last minute. The second hack is choosing the slower buses. Stick to the slower or connecting trips since these are usually priced lower than the high_speed or direct trips. The third hack is to be flexible. Compare the fares on various travel dates, and choose the day with the cheapest fares as your travel date. Finally, consider booking using the Omio app to enjoy great deals and discounts only on the Omio app or website.

Siena Piazza Grande. Source: Shutterstock
Siena is one of the most popular tourist destinations in Tuscany, Italy, a place rich in art and history and with strong local traditions. It is in Siena that the popular Palio di Siena event happens every year, twice in the summer. If you are visiting Siena, we suggest you start from the heart of the city at Piazza del Campo, a beautiful square at the heart of Siena and one of the city's landmarks. It is here that the Palio di Siena happens every July and August, and it’s the most anticipated event of the year. If you’re fascinated by medieval architecture, Siena is worth a visit. Thanks to its well_preserved medieval city, Siena old town is marked as one of Unesco’s world heritage sites. It is no surprise that Italy is a country of culinary delights, and Siena’s countless restaurants offer many opportunities to sample the breadth of Italian gastronomy. Some local Sienese favorites include pici, panforte, and pecorino of Pienza. The region is also popular for its wines, and it’s not only wine tasting offered here, with several local wineries offering lessons on the local wine_making traditions. And before you leave this rich region, make sure to:
Find answers to the most common questions about traveling from Matera to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

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