- Must visit
Vatican Museums
One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.
We are not able to find a bus between these two places.
Cheapest price
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Omio recommends booking the flight as it is the most popular option from Mannheim to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a flight which can get you there in 2h 10m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of $62, and a flight costs an average of $44.
Distance: 559 miles (900 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$93 Average price Cheapest | $170 Average price | $348 Average price (fuel + tolls) |
23h 22m Average total duration 22h 52m Onboard + 30m Additional time* | 5h 10m Average total duration Fastest 2h 10m Onboard + 3h 0m Additional time* | 12h 45m Average total duration (door-to-door) |
0.9 - 2.3kg CO2 emissions Lowest | 2.7 - 5.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mannheim to Rome:
A bus is $77 (€64) less than a flight for this route with tickets for a flight from Mannheim to Rome costing on average $170 (€140).
Other travel options to Rome take longer:
Train takes on average 16h 2m.
Bus takes on average 22h 52m.
Tickets start at around $93 (€76) compared to roughly $348 (€285) in fuel and tolls — a saving of about $255 (€209). The journey takes 22h 52m versus 12h 45m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:00AM | Arrival Time 09:10PM | Duration 19h10 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $130 |
Operator FlixBus | Departure Time 03:40AM | Arrival Time 11:00PM | Duration 19h20 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $105 |
Operator FlixBus | Departure Time 04:00AM | Arrival Time 11:40PM | Duration 19h40 | Departure days Sun | Cheapest price $121 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:05AM | Duration 21h35 | Departure days Fri, Sat | Cheapest price $88 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 05:35AM | Duration 21h05 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $102 |
Operator Marino Autolinee | Departure Time 08:35AM | Arrival Time 04:30AM | Duration 19h55 | Departure days Thu | Cheapest price $156 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 06:05AM | Duration 20h45 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $103 |
Operator FlixBus | Departure Time 10:15AM | Arrival Time 09:20AM | Duration 23h05 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 10:00AM | Duration 21h50 | Departure days Mon | Cheapest price $112 |
Operator FlixBus | Departure Time 12:35PM | Arrival Time 12:15PM | Duration 23h40 | Departure days Mon | Cheapest price $140 |
Operator BlaBlaCar Bus | Departure Time 01:30PM | Arrival Time 08:15PM | Duration 30h45 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $189 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 12:15PM | Duration 21h30 | Departure days Tue, Wed, Thu, Sun | Cheapest price $99 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 01:20PM | Duration 21h45 | Departure days Mon, Tue, Wed, Thu | Cheapest price $120 |
Operator FlixBus | Departure Time 03:50PM | Arrival Time 01:20PM | Duration 21h30 | Departure days Sun | Cheapest price $174 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 11:50AM | Duration 18h50 | Departure days Fri, Sat | Cheapest price $72 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 04:00PM | Duration 22h55 | Departure days Fri | Cheapest price $78 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 12:50PM | Duration 18h50 | Departure days Fri, Sat | Cheapest price $89 |
Operator FlixBus | Departure Time 07:00PM | Arrival Time 03:05PM | Duration 20h05 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 07:05PM | Arrival Time 05:50PM | Duration 22h45 | Departure days Mon, Thu, Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 04:45PM | Duration 20h10 | Departure days Fri, Sat | Cheapest price $116 |
Operator FlixBus | Departure Time 09:40PM | Arrival Time 06:05PM | Duration 20h25 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $125 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 06:45PM | Duration 20h10 | Departure days Mon, Thu, Sun | Cheapest price $134 |
The table below shows live departures for Mannheim to Rome buses for today, Friday, July 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:00 PM Mannheim | 18h50 | 11:50 AM Rome | 0 transfersDirect | |
![]() | 5:05 PM Mannheim | 22h55 | 4:00 PM Rome | 0 transfersDirect | |
![]() | 6:00 PM Mannheim | 18h50 | 12:50 PM Rome | 0 transfersDirect | |
![]() | 8:35 PM Mannheim | 20h10 | 4:45 PM Rome | 0 transfersDirect | |
| Saturday, July 11 | |||||
![]() | 7:30 AM Mannheim | 21h35 | 5:05 AM Rome | 0 transfersDirect | |
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Mannheim to Rome run on average 12 times per day, taking around 22h 52m. Cheap bus tickets for this journey start at $62 (€51) but you can travel from only $44 (€36) by flight.
There are 1 buses per day. The earliest bus runs at 02:00, the last at 23:40. The fastest bus covers the 559 miles (900 km) distance in 18h 45m.
Distance 559 miles (900 km) |
Average bus duration 22h 52m |
Cheapest ticket price $62 (€51) |
Buses per day 12 |
Direct buses 1 |
Fastest bus 18h 45m |
First bus 2:00 AM |
Last bus 11:40 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Mon |
Best time to book 7 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.
A superb villa museum with Bernini sculptures and major paintings by Caravaggio, Raphael, and Titian. Timed entry is essential due to limited capacity.
The city's historic civic museums on Capitoline Hill, known for classical sculpture, ancient Roman art, and excellent views over the Forum.
A lively Baroque square with monumental fountains, elegant facades, and one of the most recognizable urban spaces in Rome.
A famous stairway and gathering point linking Piazza di Spagna with Trinita dei Monti, especially popular for photos and central city strolls.
A beloved neighborhood of narrow lanes, ivy-covered buildings, and lively Roman atmosphere, ideal for wandering day or night.
A classic Roman pasta with pecorino Romano, black pepper, and pasta water. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is a defining dish of Rome and is famously made without cream.
A beloved pasta sauce of tomato, guanciale, pecorino Romano, and chili. Though linked to Amatrice, it is deeply rooted in Roman trattoria cooking.
Rome’s best-known luxury fine-dining restaurant, famous for panoramic views, elegant service, and sophisticated Italian cuisine.
A historic restaurant near the Pantheon serving refined Roman classics with strong local identity. Well known for seasonal specialties and pasta.
A celebrated central Rome dining room known for Roman pasta, cured meats, and an exceptional wine list. Lively, polished, and very popular.
Moderate for Western Europe. Sights and central hotels cost more, but food, coffee, and transit can be good value.
Service is often included or modest. Locals may round up or leave EUR 1-2 at cafes; 5-10% is appreciated at restaurants for good service, not obligatory. Round up taxis.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola, Rome -> Rome Termini
Find answers to the most common questions about traveling from Mannheim to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Mannheim to Rome buses use the Mannheim, ZOB (Heinrich-Von-Stephan-Straße) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Mannheim and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need