- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
Cheapest price
$52
Average price
$60
Fastest journey
4 h 50 m
Average duration
4 h 50 m
Buses per day
2
Distance
438 km
The best way to find a cheap bus ticket from Lawrence, KS to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lawrence, KS to St. Louis, MO will cost around $60 if you buy it on the day, but the cheapest tickets can be found for only $52.
Of the 2 buses that leave Lawrence, KS for St. Louis, MO on Sat, Jun 27, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 27 the direct buses cover the 438 km distance in an average of 4 h 50 m but if you time it right, some buses will get you there in just 4 h 50 m .
On Sat, Jun 27 the slowest buses will take 4 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Lawrence, KS to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $41. For those with little time consider booking a flight which can get you there in 4h 53m. The ticket price range depends on the travel mode: a bus costs an average of $41, and a flight costs an average of $171.
Distance: 272 miles (438 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$55 Average price Cheapest | $310 Average price | $60 Average price | $62 Average price (fuel + tolls) |
5h 35m Average total duration 5h 5m Onboard + 30m Additional time* | 7h 53m Average total duration Fastest 4h 53m Onboard + 3h 0m Additional time* | 12h 38m Average total duration 12h 8m Onboard + 30m Additional time* | 4h 21m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lawrence, KS to St. Louis, MO:
A bus is $5 (€4) less than a train for this route with tickets for a train from Lawrence, KS to St. Louis, MO costing on average $60 (€49).
A bus is $254 (€208) less than a flight for this route with tickets for a flight from Lawrence, KS to St. Louis, MO costing on average $310 (€254).
Other travel options to St. Louis, MO take longer:
Bus takes on average 5h 5m.
Train takes on average 12h 8m.
Tickets start at around $55 (€45) compared to roughly $62 (€51) in fuel and tolls — a saving of about $7 (€5). The journey takes 5h 5m versus 4h 21m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:00AM | Arrival Time 04:50AM | Duration 4h50 | Departure days Mon, Thu, Sun | Cheapest price $41 |
Operator Greyhound | Departure Time 01:35AM | Arrival Time 08:00AM | Duration 6h25 | Departure days Mon, Fri | Cheapest price $48 |
Operator Greyhound | Departure Time 07:05AM | Arrival Time 12:55PM | Duration 5h50 | Departure days Mon, Fri | Cheapest price $57 |
Operator Greyhound USA | Departure Time 06:00PM | Arrival Time 10:50PM | Duration 4h50 | Departure days Thu | Cheapest price $85 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 03:50AM | Duration 5h00 | Departure days Tue | Cheapest price $43 |
Operator Greyhound | Departure Time 11:00PM | Arrival Time 03:50AM | Duration 4h50 | Departure days Tue, Wed, Sat, Sun | Cheapest price $56 |
The table below shows live departures for Lawrence, KS to St. Louis, MO buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:00 PM Lawrence, KS | 4h50 | 3:50 AM St. Louis, MO | 0 transfersDirect | |
| Sunday, June 21 | |||||
![]() | 12:00 AM Lawrence, KS | 4h50 | 4:50 AM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lawrence, KS to St. Louis, MO run on average 2 times per day, taking around 5h 5m. Cheap bus tickets for this journey start at $41 (€34) if you book in advance.
There are 1 buses per day. The earliest bus runs at 01:00, the last at 19:30. The fastest bus covers the 272 miles (438 km) distance in 4h 50m.
Distance 272 miles (438 km) |
Average bus duration 5h 5m |
Cheapest ticket price $41 (€34) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 4h 50m |
First bus 1:00 AM |
Last bus 7:30 PM |
Cheapest Month Jan |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 35 days |
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
Highly original museum and artist-built environment with architectural salvage, tunnels, slides, and installations. One of the city’s most distinctive and widely shared attractions.
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Well suited for visitors wanting local context.
One of the largest urban parks in the United States, home to major institutions, lakes, trails, and broad green spaces. Essential for first-time visitors.
Riverfront grounds around the Arch with lawns, paths, and strong skyline views, useful for walking and iconic photos.
Lively entertainment and walking district known for music venues, public art, shops, and the St. Louis Walk of Fame.
A local pizza style with a very thin, cracker-like crust, cut into squares and traditionally topped with Provel cheese. It is one of the city’s signature foods.
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara sauce. This St. Louis Italian-American specialty is strongly associated with The Hill neighborhood.
A rich, dense cake with a buttery base and sweet cream cheese-like topping. It is one of the most famous desserts identified with St. Louis.
A long-established Italian restaurant on The Hill, known for classic red-sauce dishes, toasted ravioli, and an old-school fine dining feel.
An iconic St. Louis custard stand famous for thick concretes and nostalgic roadside charm. A must for trying the city’s best-known frozen treat.
A respected contemporary American restaurant known for refined cooking, strong wine service, and a polished neighborhood setting.
Generally moderate by U.S. standards. Hotels and attractions are often reasonable, while dining costs vary by neighborhood and venue.
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Lawrence, KS to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Lawrence, KS to St. Louis, MO buses use the Lawrence, Central Station to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Lawrence, KS and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need