Travel Information
Compare train, bus, and flight for Lafayette, IN to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Lafayette, IN to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $44. For those with little time consider booking a flight which can get you there in 5h 11m. The ticket price range depends on the travel mode: a bus costs an average of $44, and a flight costs an average of $357.
Distance: 216 miles (348 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$47 Average price Cheapest | $90 Average price | $358 Average price |
6h 45m Average total duration 6h 15m Onboard + 30m Additional time* | 11h 51m Average total duration 11h 21m Onboard + 30m Additional time* | 8h 11m Average total duration Fastest 5h 11m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Lafayette, IN to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Lafayette, IN to St. Louis, MO buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lafayette, IN to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lafayette, IN to St. Louis, MO.
Journey information
Overview: Bus from Lafayette, IN to St. Louis, MO
Buses from Lafayette, IN to St. Louis, MO run on average 4 times per day, taking around 6h 15m. Cheap bus tickets for this journey start at $44 (€36) if you book in advance.
The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 216 miles (348 km) distance in 7h 25m.
Distance 216 miles (348 km) |
Average bus duration 6h 15m |
Cheapest ticket price $44 (€36) |
Buses per day 4 |
Fastest bus 7h 25m |
First bus 02:00 |
Last bus 23:30 |
Bus providers: Greyhound from Lafayette, IN to St. Louis, MOYou can travel by bus between Lafayette, IN to St. Louis, MO with Greyhound for as low as $44 (€36). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Lafayette, IN to St. Louis, MO
Find answers to the most common questions about traveling from Lafayette, IN to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Lafayette, IN to St. Louis, MO
Most popular bus connections from Lafayette, IN
More options for your journey from Lafayette, IN to St. Louis, MO
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