The cheapest and fastest buses from Jackson, MS to St. Louis, MO
Cheapest price
$85
Average price
$97
Fastest journey
10 h 5 m
Average duration
15 h 48 m
Buses per day
2
Distance
704 km
The best way to find a cheap bus ticket from Jackson, MS to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jackson, MS to St. Louis, MO will cost around $97 if you buy it on the day, but the cheapest tickets can be found for only $85.
Of the 2 buses that leave Jackson, MS for St. Louis, MO on Thu, Nov 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 06 the direct buses cover the 704 km distance in an average of 15 h 48 m but if you time it right, some buses will get you there in just 10 h 5 m .
On Thu, Nov 06 the slowest buses will take 21 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Jackson, MS to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Jackson, MS to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €54. For those with little time consider booking a flight which can get you there in 3h 42m. The ticket price range depends on the travel mode: a bus costs an average of €54, and a flight costs an average of €226.
Distance: 437 miles (704 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€102 Average price Cheapest | €144 Average price | €272 Average price |
15h 20m Average total duration 14h 50m Onboard + 30m Additional time* | 11h 57m Average total duration 11h 27m Onboard + 30m Additional time* | 6h 42m Average total duration Fastest 3h 42m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Jackson, MS to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55PM | Arrival Time 11:00PM | Duration 10h05 | Departure days Fri | Cheapest price $77 |
Live departures
Jackson, MS to St. Louis, MO bus times
The table below shows live departures for Jackson, MS to St. Louis, MO buses for today, Wednesday, November 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:55 PM Jackson, MS | 10h05 | 4:00 AM St. Louis, MO | 0 transfersDirect | |
![]() | 11:25 PM Jackson, MS | 21h30 | 8:55 PM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Jackson, MS to St. Louis, MO by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
Nov 07
Nov 08
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Nov 11
Nov 12
Journey information
Overview: Bus from Jackson, MS to St. Louis, MO
Distance 437 miles (704 km) |
Average bus duration 14h 50m |
Cheapest ticket price $66 (€54) |
Buses per day 2 |
Fastest bus 10h 5m |
First bus 01:00 |
Last bus 23:45 |
Bus providers: Greyhound from Jackson, MS to St. Louis, MOYou can travel by bus between Jackson, MS to St. Louis, MO with Greyhound for as low as $66 (€54). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Jackson, MS to St. Louis, MO

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Jackson, MS to St. Louis, MO, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Jackson, MS to St. Louis, MO
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