- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
Cheapest price
$71
Average price
$71
Fastest journey
5 h 29 m
Average duration
5 h 29 m
Buses per day
1
Distance
153 km
The best way to find a cheap bus ticket from Effingham, IL to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Effingham, IL to St. Louis, MO will cost around $71 if you buy it on the day, but the cheapest tickets can be found for only $71.
Of the 1 buses that leave Effingham, IL for St. Louis, MO on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 153 km distance in an average of 5 h 29 m but if you time it right, some buses will get you there in just 5 h 29 m .
On Sun, Jun 21 the slowest buses will take 5 h 29 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Effingham, IL to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $63. For those with little time consider booking a bus which can get you there in 1h 40m. The ticket price range depends on the travel mode: a bus costs an average of $63, and a train costs an average of $77.
Distance: 95 miles (153 km)
Most popular Bus | Train | Driving |
|---|---|---|
$69 Average price Cheapest | $245 Average price | $21 Average price (fuel + tolls) |
2h 10m Average total duration Fastest 1h 40m Onboard + 30m Additional time* | 14h 1m Average total duration 13h 31m Onboard + 30m Additional time* | 1h 31m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Effingham, IL to St. Louis, MO:
A bus is $176 (€144) less than a train for this route with tickets for a train from Effingham, IL to St. Louis, MO costing on average $245 (€200).
Other travel options to St. Louis, MO take longer:
Train takes on average 13h 31m.
You'll arrive about -1h -9m sooner (1h 40m by bus vs 1h 31m by car) and save roughly $-47.82 (€-39.14) compared to fuel and tolls ($69 (€56) vs $21 (€17)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 05:01AM | Arrival Time 10:30AM | Duration 5h29 | Departure days Mon, Tue, Sat, Sun | Cheapest price $63 |
The table below shows live departures for Effingham, IL to St. Louis, MO buses for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:01 AM Effingham, IL | 5h29 | 10:30 AM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Effingham, IL to St. Louis, MO run on average 2 times per day, taking around 1h 40m. Cheap bus tickets for this journey start at $63 (€52) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:01, the last at 23:37. The fastest bus covers the 95 miles (153 km) distance in 5h 29m.
Distance 95 miles (153 km) |
Average bus duration 1h 40m |
Cheapest ticket price $63 (€52) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 5h 29m |
First bus 12:01 AM |
Last bus 11:37 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Tue |
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
Highly original museum and artist-built environment with architectural salvage, tunnels, slides, and installations. One of the city’s most distinctive and widely shared attractions.
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Well suited for visitors wanting local context.
One of the largest urban parks in the United States, home to major institutions, lakes, trails, and broad green spaces. Essential for first-time visitors.
Riverfront grounds around the Arch with lawns, paths, and strong skyline views, useful for walking and iconic photos.
Lively entertainment and walking district known for music venues, public art, shops, and the St. Louis Walk of Fame.
A local pizza style with a very thin, cracker-like crust, cut into squares and traditionally topped with Provel cheese. It is one of the city’s signature foods.
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara sauce. This St. Louis Italian-American specialty is strongly associated with The Hill neighborhood.
A rich, dense cake with a buttery base and sweet cream cheese-like topping. It is one of the most famous desserts identified with St. Louis.
A long-established Italian restaurant on The Hill, known for classic red-sauce dishes, toasted ravioli, and an old-school fine dining feel.
An iconic St. Louis custard stand famous for thick concretes and nostalgic roadside charm. A must for trying the city’s best-known frozen treat.
A respected contemporary American restaurant known for refined cooking, strong wine service, and a polished neighborhood setting.
Generally moderate by U.S. standards. Hotels and attractions are often reasonable, while dining costs vary by neighborhood and venue.
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Effingham, IL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Effingham, IL to St. Louis, MO buses use the Effingham, N 3rd St (Greyhound Bus Station) to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Effingham, IL and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need