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4.6
Travel Information
Compare train, bus, and flight for Chicago, IL to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Chicago, IL to St. Louis, MO among Omio's users. If you are prioritising price take the train with prices starting from $31. For those with little time consider booking a flight which can get you there in 1h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a train costs an average of $31, and a flight costs an average of $72.
Distance: 260 miles (419 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$61 Average price Cheapest | $72 Average price | $404 Average price | $61 Average price (fuel + tolls) |
5h 30m Average total duration 5h 0m Onboard + 30m Additional time* | 6h 57m Average total duration 6h 27m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 1h 21m Onboard + 3h 0m Additional time* | 4h 11m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.3 - 2.5kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Chicago, IL to St. Louis, MO:
A train is $11 (€8) less than a bus for this route with tickets for a bus from Chicago, IL to St. Louis, MO costing on average $72 (€58).
A train is $342 (€276) less than a flight for this route with tickets for a flight from Chicago, IL to St. Louis, MO costing on average $404 (€326).
Other travel options to St. Louis, MO take longer:
Train takes on average 5h 0m.
Bus takes on average 6h 27m.
Travel optionsfrom Chicago, IL to St. Louis, MO
How to get from Chicago, IL to St. Louis, MO by train, bus or flight.
Our recommendation
The best way to travel from Chicago, IL to St. Louis, MO is by taking a train because it’s the best combination of price and speed.
- 307 Lincoln Service7:10 PM4h59Chicago Union Station, Chicago, IL12:09 AMSt. Louis Station, St. Louis, MO$461One-way0 transfers
Cheapest
- 307 Lincoln Service7:10 PM4h59Chicago Union Station, Chicago, IL12:09 AMSt. Louis Station, St. Louis, MO$461One-way0 transfers
Fastest
AA100410:40 PM1h14O'Hare International Airport11:54 PMSt. Louis Lambert International Airport$4081One-way0 transfers
Other options
- 301 Lincoln Service7:15 AM4h46Chicago Union Station, Chicago, IL12:01 PMSt. Louis Station, St. Louis, MO$791One-way0 transfers
- 305 Lincoln Service5:20 PM5h03Chicago Union Station, Chicago, IL10:23 PMSt. Louis Station, St. Louis, MO$791One-way0 transfers
- 319 Lincoln Service Missouri River Runner9:50 AM5h01Chicago Union Station, Chicago, IL2:51 PMSt. Louis Station, St. Louis, MO$1081One-way0 transfers
- FlixBus12:15 AM6h10Chicago, Greyhound Bus Station6:25 AMSt. Louis, S 15th St (Civic center)$611One-way0 transfers
- FlixBus9:45 AM5h55Chicago, Greyhound Bus Station3:40 PMSt. Louis, S 15th St (Civic center)$621One-way0 transfers
- FlixBus5:15 PM6h05Chicago, Greyhound Bus Station11:20 PMSt. Louis, S 15th St (Civic center)$621One-way0 transfers
- UA20002:20 PM1h26O'Hare International Airport3:46 PMSt. Louis Lambert International Airport$4081One-way0 transfers
AA381512:40 PM1h26O'Hare International Airport2:06 PMSt. Louis Lambert International Airport$4081One-way0 transfers- AA4397:04 PM1h26O'Hare International Airport8:30 PMSt. Louis Lambert International Airport$4081One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Chicago, IL to St. Louis, MO
Travel to St. Louis, MO easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Chicago, IL to St. Louis, MO.
This is compared to other travel options from Chicago, IL to St. Louis, MO:
A train is $11 (€8) less than a bus for this route with tickets for a bus from Chicago, IL to St. Louis, MO costing on average $72 (€58).
A train is $342 (€276) less than a flight for this route with tickets for a flight from Chicago, IL to St. Louis, MO costing on average $404 (€326).
Other travel options to St. Louis, MO take longer:
Train takes on average 5h 0m.
Bus takes on average 6h 27m.
- Around 24 flights per day.
- Around 6 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Chicago, IL and St. Louis, MO as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from O'Hare International Airport and arrive in St. Louis Lambert International Airport.
- Buses mostly depart from Chicago, Greyhound Bus Station and arrive in St. Louis, S 15th St (Civic center).
- Trains mostly depart from Chicago Union Station, Chicago, IL and arrive in St. Louis Station, St. Louis, MO.
- Travel with United, American Airlines, Republic Airlines to go to St. Louis, MO by flight.
- Travel with Amtrak to go to St. Louis, MO by train.
- Travel with FlixBus, Greyhound to go to St. Louis, MO by bus.
- 8 direct flights per day with United, American Airlines, Republic Airlines.
- 5 direct trains per day with Amtrak.
- 2 direct buses per day with FlixBus, Greyhound.
Travelling from Chicago, IL to St. Louis, MO: related information
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