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Travel Information
Compare train, bus, and flight for Chicago, IL to St. Louis, MO
Omio recommends booking the flight as it is the most popular option from Chicago, IL to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $66 For those with little time, consider booking a train, which has an average total journey time of 5h 32m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $66, while a flight costs an average of $628.
Distance: 260 miles (419 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$628 Average price | $84 Average price | $66 Average price Cheapest | $59 Average price (fuel + tolls) |
6h 33m Average total duration 4h 33m Onboard + 2h 0m Additional time* | 5h 32m Average total duration Fastest 5h 2m Onboard + 30m Additional time* | 7h 44m Average total duration 7h 14m Onboard + 30m Additional time* | 4h 11m Average total duration (door-to-door) |
1.3 - 2.5kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | - CO2 emissions |
 Most popular airline |  Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Chicago, IL to St. Louis, MO:
A bus is $18 (€15) less than a train for this route with tickets for a train from Chicago, IL to St. Louis, MO costing on average $84 (€71).
A bus is $561 (€472) less than a flight for this route with tickets for a flight from Chicago, IL to St. Louis, MO costing on average $628 (€528).
Other travel options to St. Louis, MO take longer:
Flight takes on average 6h 33m.
Bus takes on average 7h 44m.
Tickets start at around $628 (€528) compared to roughly $59 (€50) in fuel and tolls — a saving of about $-568.63 (€-477.87). The journey takes 4h 33m versus 4h 11m by car, so you may arrive a little later, but you can relax instead of spending the time behind the wheel.
Driving is worth considering if you're on a tight schedule, travelling as a group, or want the flexibility to stop along the way.
Travel optionsfrom Chicago, IL to St. Louis, MO
How to get from Chicago, IL to St. Louis, MO by train, bus or flight.
Our recommendation
The best way to travel from Chicago, IL to St. Louis, MO is by taking a bus because it’s the best combination of price and speed.
FlixBus5:05 PM6h15Chicago, Greyhound Bus Station11:20 PMSt. Louis, S 15th St (Civic center)$551One-way0 transfers
Cheapest
- FlixBus5:05 PM6h15Chicago, Greyhound Bus Station11:20 PMSt. Louis, S 15th St (Civic center)$551One-way0 transfers
Fastest
- UA44163:35 PM1h26O'Hare International Airport5:01 PMSt. Louis Lambert International Airport$3981One-way0 transfers
Other options
- 301 Lincoln Service7:15 AM4h46Chicago Union Station, Chicago, IL12:01 PMSt. Louis Station, St. Louis, MO$551One-way0 transfers
- 307 Lincoln Service7:10 PM4h59Chicago Union Station, Chicago, IL12:09 AMSt. Louis Station, St. Louis, MO$651One-way0 transfers
- 319 Lincoln Service Missouri River Runner9:50 AM5h01Chicago Union Station, Chicago, IL2:51 PMSt. Louis Station, St. Louis, MO$651One-way0 transfers
- FlixBus9:45 AM5h55Chicago, Greyhound Bus Station3:40 PMSt. Louis, S 15th St (Civic center)$661One-way0 transfers
- FlixBus12:15 AM6h05Chicago, Greyhound Bus Station6:20 AMSt. Louis, S 15th St (Civic center)$801One-way0 transfers
- · 2:45 PM8h30Chicago, Greyhound Bus Station11:15 PMSt. Louis, S 15th St (Civic center)$811One-way1 transfer
- UA45769:30 PM1h29O'Hare International Airport10:59 PMSt. Louis Lambert International Airport$3491One-way0 transfers
- UA44126:10 PM1h31O'Hare International Airport7:41 PMSt. Louis Lambert International Airport$3491One-way0 transfers
- UA20002:12 PM1h31O'Hare International Airport3:43 PMSt. Louis Lambert International Airport$3491One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Chicago, IL to St. Louis, MO
Travel to St. Louis, MO easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Chicago, IL to St. Louis, MO.
This is compared to other travel options from Chicago, IL to St. Louis, MO:
A bus is $18 (€15) less than a train for this route with tickets for a train from Chicago, IL to St. Louis, MO costing on average $84 (€71).
A bus is $561 (€472) less than a flight for this route with tickets for a flight from Chicago, IL to St. Louis, MO costing on average $628 (€528).
Other travel options to St. Louis, MO take longer:
Flight takes on average 6h 33m.
Bus takes on average 7h 44m.
- Around 44 flights per day.
- Around 6 buses per day.
- Around 5 trains per day.
However, we recommend checking specific travel dates for your route between Chicago, IL and St. Louis, MO as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from O'Hare International Airport and arrive in St. Louis Lambert International Airport.
- Trains mostly depart from Chicago Union Station, Chicago, IL and arrive in St. Louis Station, St. Louis, MO.
- Buses mostly depart from Chicago, Greyhound Bus Station and arrive in St. Louis, S 15th St (Civic center).
- Travel with American Airlines, Republic Airlines, United, skywest airlines, psa airlines to go to St. Louis, MO by flight.
- Travel with Amtrak to go to St. Louis, MO by train.
- Travel with Greyhound, FlixBus to go to St. Louis, MO by bus.
- 11 direct flights per day with American Airlines, Republic Airlines, United, skywest airlines.
- 5 direct trains per day with Amtrak.
- 3 direct buses per day with FlixBus.
Travelling from Chicago, IL to St. Louis, MO: related information
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