How to travel from Chicago, IL to St. Louis, MO

Fri, May 31
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Travel Information to St. Louis, MO from Chicago, IL

distanceDistance259 miles (418 km)
modeAvailable travel modesTrain, bus or flight
priceTicket price range$34 - $75
cheapestCheapest modeBus • $34 (€29) • 5 h 50 min
fastestFastest modeFlight • $75 (€65) • 1 h 12 min
carriersPopular travel companiesGreyhound, Republic Airlines or Amtrak

Travel 259 miles (418 km) by train, bus or flight between Chicago, IL and St. Louis, MO. The most popular travel companies which serve this trip are Greyhound, Republic Airlines or Amtrak among others. Travelers can even take a direct bus, flight or train from Chicago, IL to St. Louis, MO.

Travel options
from Chicago, IL to St. Louis, MO

How to get from Chicago, IL to St. Louis, MO by train, bus or flight.

Our recommendation
train

The best way to travel from Chicago, IL to St. Louis, MO is by taking a train because it’s the best combination of price and speed.

Amtrak
07:15AM4h46
Union Station, Chicago, IL
12:01PMSt. Louis Station, St. Louis, MO
$631One-way
0 transfers
Cheapest
Amtrak
07:15AM4h46
Union Station, Chicago, IL
12:01PMSt. Louis Station, St. Louis, MO
$631One-way
0 transfers
Fastest
American Airlines
03:04PM1h13
O'Hare International Airport, IL (ORD)
04:17PMSt. Louis Lambert International Airport, MO (STL)
$2831One-way
0 transfers
Other options
Amtrak
09:50AM5h01
Union Station, Chicago, IL
02:51PMSt. Louis Station, St. Louis, MO
$771One-way
0 transfers
Amtrak
07:10PM4h59
Union Station, Chicago, IL
12:09AMSt. Louis Station, St. Louis, MO
$771One-way
0 transfers
Amtrak
05:20PM5h03
Union Station, Chicago, IL
10:23PMSt. Louis Station, St. Louis, MO
$921One-way
0 transfers
FlixBus
06:00AM5h55
Chicago, IL
11:55AMSt. Louis, MO
$781One-way
0 transfers
FlixBus
06:50PM5h50
Chicago, IL
12:40AMSt. Louis, MO
$831One-way
0 transfers
FlixBus
07:05PM5h35
Chicago, IL
12:40AMSt. Louis, MO
$831One-way
0 transfers
Republic Airlines
08:45AM1h23
O'Hare International Airport, IL (ORD)
10:08AMSt. Louis Lambert International Airport, MO (STL)
$2811One-way
0 transfers
Republic Airlines
12:50PM1h24
O'Hare International Airport, IL (ORD)
02:14PMSt. Louis Lambert International Airport, MO (STL)
$2811One-way
0 transfers
United
02:20PM1h21
O'Hare International Airport, IL (ORD)
03:41PMSt. Louis Lambert International Airport, MO (STL)
$2811One-way
0 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

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May 31
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All travel companies: Airlines, Train and Bus from Chicago to St. Louis

Travel to St. Louis from Chicago on Amtrak, FlixBus and American Airlines travel with Omio. When comparing schedules and tickets, we will also show you other options with multiple connections or other travel modes if they’re available.

Amtrak is the main travel company in the United States and operates medium and long-distance intercity services in 46 American states and 3 Canadian provinces. With over 300 Amtrak travel running daily, you can travel by travel across America and explore destinations near and far. Take the Acela travel for high-speed services connecting popular cities in the Northeast, the Coast Starlight to travel up and down the stunning West Coast or the Empire Builder to travel from Chicago to the Midwest and the Pacific Northwest among others. Amtrak offers different class options to suit any traveler’s budget with classes like Coach, Business, First and the Sleeper Class, where you can book a Roomette, Bedroom, and Bedroom suite among others for night travel. When you book your travel journey between Chicago and St. Louis, you can choose between ticket types like Saver, Value, Flexible, Business and Premium.

      United Airlines is one of the USA’s leading airline and operates domestic and international routes. Economy, Premium Economy and Business are the ticket fares that the airline offers for your next travel from Chicago to St. Louis.

        FAQs: Travel from Chicago, IL to St. Louis, MO

        FAQs: Travel to St. Louis, MO easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Chicago, IL to St. Louis, MO.
        FAQs

        There are 3 travel options from Chicago, IL to St. Louis, MO: train, bus or flight.

        The cheapest way to get from Chicago, IL to St. Louis, MO is by taking a bus with average ticket prices of $34 (€29) compared to other travel options to St. Louis, MO:

        A bus is $41 (€36) less than a flight for this journey with tickets for a flight from Chicago, IL to St. Louis, MO costing on average $75 (€65).

        A bus is $2 (€2) less than a train for this journey with tickets for a train from Chicago, IL to St. Louis, MO costing on average $36 (€31).

        The fastest way from Chicago, IL to St. Louis, MO is by flight with an average journey time of 1 h 12 min.

        There are alternative travel options to St. Louis, MO that take longer:

        Taking a bus requires on average 5 h 50 min of travel time.

        Taking a train requires on average 4 h 46 min of travel time.

        St. Louis, MO is approximately 259 miles (418 km) away from Chicago, IL.

        The average frequency per day from Chicago, IL to St. Louis, MO is:

        • 1 bus per day.
        • Around 4 trains per day.

        However, we recommend checking specific travel dates for your route between Chicago, IL and St. Louis, MO as scheduled services by train, bus or flight can vary by season or day of the week.

        These are the most popular departure and arrival points when traveling from Chicago, IL to St. Louis, MO:

          The following travel companies offer services from Chicago, IL to St. Louis, MO:

          • Travel with Greyhound or FlixBus to go to St. Louis, MO by bus. For a good deal on tickets, you can find Greyhound Chicago, IL to St. Louis, MO tickets on Omio for $34 (€29).
          • Travel with Republic Airlines, United, American Airlines, Alaska Airlines, Sky West Airlines, Mesa Airlines or Adam Turs for flights to St. Louis, MO. If you’re looking for a good deal on tickets, check for American Airlines Chicago, IL to St. Louis, MO tickets on Omio for $75 (€65).
          • Amtrak can get you to St. Louis, MO by train. You can find a good deal for train tickets with Amtrak from Chicago, IL to St. Louis, MO for $36 (€31) on Omio.

          Yes, there are direct routes from Chicago, IL to St. Louis, MO with the following travel companies:

          • You can check for a direct bus to St. Louis, MO with Greyhound with 1 direct bus per day.
          • You can find 4 direct trains per day to take to St. Louis, MO with Amtrak.

          Direct services to St. Louis, MO tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your trip.

          Many of our customers traveling from Chicago, IL to St. Louis, MO don't make St. Louis, MO their final stop. Some of the destinations worth visiting after St. Louis, MO are Jefferson City, MO, Kansas City, KS, Joliet, IL or Rolla, MO, either of which you could add to your trip itinerary. Check Omio for the best and cheapest ways to travel from St. Louis, MO to any of these top destinations today!

          Travel to popular destinations by train, bus or flight

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