- Must visit
USS Midway Museum
Museum aboard the historic aircraft carrier USS Midway with restored aircraft, flight deck exhibits, and audio tours on San Diego Bay.
Cheapest price
$760
Average price
$760
Fastest journey
2 d 15 h 5 m
Average duration
2 d 15 h 5 m
Buses per day
1
Distance
3514 km
The best way to find a cheap bus ticket from Buffalo, NY to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to San Diego, CA will cost around $760 if you buy it on the day, but the cheapest tickets can be found for only $760.
It's difficult to get from Buffalo, NY to San Diego, CA without transferring at least 3 times.


Omio recommends booking the bus as it is the most popular option from Buffalo, NY to San Diego, CA among Omio's users. If you are prioritising price take the train with prices starting from $262. For those with little time consider booking a flight which can get you there in 9h 10m. The ticket price range depends on the travel mode: a train costs an average of $262, and a flight costs an average of $160.
Distance: 2183 miles (3514 km)
Most popular Bus | Train | Flight |
|---|---|---|
$282 Average price | $263 Average price Cheapest | $332 Average price |
80h 4m Average total duration 79h 34m Onboard + 30m Additional time* | 63h 58m Average total duration 63h 28m Onboard + 30m Additional time* | 12h 10m Average total duration Fastest 9h 10m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Buffalo, NY to San Diego, CA:
A train is $19 (€15) less than a bus for this route with tickets for a bus from Buffalo, NY to San Diego, CA costing on average $282 (€228).
A train is $69 (€56) less than a flight for this route with tickets for a flight from Buffalo, NY to San Diego, CA costing on average $332 (€269).
Other travel options to San Diego, CA take longer:
Train takes on average 63h 28m.
Bus takes on average 79h 34m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:05AM | Arrival Time 12:45AM | Duration 69h40 | Departure days Wed | Cheapest price $239 |
Operator Greyhound | Departure Time 04:20AM | Arrival Time 05:15AM | Duration 96h55 | Departure days Sun | Cheapest price $267 |
Operator Barons Bus | Departure Time 02:20PM | Arrival Time 05:25AM | Duration 63h05 | Departure days Wed, Fri | Cheapest price $760 |
Operator Greyhound | Departure Time 09:20PM | Arrival Time 01:10AM | Duration 75h50 | Departure days Thu, Sun | Cheapest price $251 |
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Buffalo, NY to San Diego, CA run on average 12 times per day, taking around 79h 34m. Cheap bus tickets for this journey start at $239 (€194) but you can travel from only $160 (€130) by flight.
The earliest bus runs at 06:45, the last at 23:20. The fastest bus covers the 2183 miles (3514 km) distance in 69h 40m.
Distance 2183 miles (3514 km) |
Average bus duration 79h 34m |
Cheapest ticket price $239 (€194) |
Buses per day 12 |
Fastest bus 69h 40m |
First bus 6:45 AM |
Last bus 11:20 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Apr - Jun |
Best time to book 28 days |
Discover the best of San Diego — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego trip today.
Museum aboard the historic aircraft carrier USS Midway with restored aircraft, flight deck exhibits, and audio tours on San Diego Bay.
Balboa Park art museum known for Spanish old masters, South Asian works, and rotating exhibitions in a landmark building.
Leading contemporary art museum with major postwar and current works, especially strong in Southern California and Pacific Rim artists.
Vast cultural park with gardens, museums, Spanish Colonial Revival architecture, walking paths, and some of San Diego's best photo spots.
Scenic cove known for sea lions, clear water, coastal cliffs, and highly shareable sunset and ocean-view walks.
Wide sandy beach beside the Hotel del Coronado, popular for walking, photography, and classic Southern California scenery.
Beer-battered or grilled local fish in tortillas, usually topped with cabbage, crema, and salsa. A signature coastal San Diego staple with strong Baja influence.
A San Diego original burrito filled with carne asada, fries, cheese, and salsa. It is one of the city’s most iconic late-night and casual foods.
French fries topped with carne asada, cheese, guacamole, sour cream, and salsa. This indulgent dish is strongly associated with San Diego taco shop culture.
Popular waterfront seafood restaurant serving fresh local catch, fish tacos, and sandwiches in a relaxed harbor setting near the fishing fleet.
Historic, no-frills Mexican restaurant famous for house-made tortillas, rolled tacos, and comforting traditional plates. A beloved local institution with a classic atmosphere.
Iconic casual spot in Ocean Beach known for oversized burgers, fries, and a lively beach-town vibe. A long-standing San Diego favorite.
Prices are high by U.S. standards, especially for hotels, dining, and parking near the coast and downtown.
Tip 18-20% at restaurants, 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and valet.
Find answers to the most common questions about traveling from Buffalo, NY to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

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