The cheapest and fastest buses from Buffalo, NY to San Diego, CA
Cheapest price
$755
Average price
$755
Fastest journey
2 d 15 h 5 m
Average duration
2 d 15 h 5 m
Buses per day
1
Distance
3514 km
The best way to find a cheap bus ticket from Buffalo, NY to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to San Diego, CA will cost around $755 if you buy it on the day, but the cheapest tickets can be found for only $755.
It's difficult to get from Buffalo, NY to San Diego, CA without transferring at least 3 times.


Travel Information
Compare train, bus, and flight for Buffalo, NY to San Diego, CA
Omio recommends booking the bus as it is the most popular option from Buffalo, NY to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $236. For those with little time consider booking a flight which can get you there in 9h 13m. The ticket price range depends on the travel mode: a bus costs an average of $236, and a train costs an average of $332.
Distance: 2183 miles (3514 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$253 Average price Cheapest | $859 Average price | $377 Average price |
84h 10m Average total duration 83h 40m Onboard + 30m Additional time* | 63h 58m Average total duration 63h 28m Onboard + 30m Additional time* | 12h 13m Average total duration Fastest 9h 13m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Buffalo, NY to San Diego, CA bus times
The table below shows live departures for Buffalo, NY to San Diego, CA buses for today, Tuesday, March 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:20 PM Buffalo, NY | 63h05 | 5:25 AM San Diego, CA | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Buffalo, NY to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Buffalo, NY to San Diego, CA
Buses from Buffalo, NY to San Diego, CA run on average 13 times per day, taking around 83h 40m. Cheap bus tickets for this journey start at $236 (€192) but you can travel from only $215 (€175) by flight.
The earliest bus runs at 06:45, the last at 23:20. The fastest bus covers the 2183 miles (3514 km) distance in 76h 0m.
Distance 2183 miles (3514 km) |
Average bus duration 83h 40m |
Cheapest ticket price $236 (€192) |
Buses per day 13 |
Fastest bus 76h 0m |
First bus 06:45 |
Last bus 23:20 |
FAQs: Bus from Buffalo, NY to San Diego, CA
Find answers to the most common questions about traveling from Buffalo, NY to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
popular bus stations
Popular bus stations from Buffalo, NY to San Diego, CA
More options for your journey from Buffalo, NY to San Diego, CA
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