- Must visit
San Diego Museum of Art
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
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The cheapest and fastest buses from Buffalo, NY to San Diego, CA
Showing times, prices and bookable tickets for Oct 30
- Cheapest price on Oct 30
- $226
- Average ticket price on Oct 30
- $424
- Fastest journey on Oct 30
- 2 d 13 h 50 m
- Average journey duration on Oct 30
- 2 d 16 h 7 m
- Buses on Oct 30
- 16
- Distance
- 3514 km
Cheap tickets
The best way to find a cheap bus ticket from Buffalo, NY to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to San Diego, CA will cost around $424 if you buy it on the day, but the cheapest tickets can be found for only $226.
Fast buses
It's difficult to get from Buffalo, NY to San Diego, CA without transferring at least 5 times.
· · · 11:05 PM 70h05 Buffalo, NFTA Metro Center 5:10 PM San Diego, Rail Ct / E San Ysidro Blvd (McDonald`s), CA $226 1 One-way 5 transfers- · · ·
11:05 PM 65h15 Buffalo, NFTA Metro Center 12:20 PM San Diego, San Ysidro Transit Center $253 1 One-way 5 transfers 
FlixBus · FlixBus+ · 1:05 PM 81h15 Cheektowaga, BNIA Drway & BNIA Terminal 6:20 PM San Diego, San Ysidro Transit Center $360 1 One-way 4 transfers- FlixBus · FlixBus+ ·
11:20 PM 89h00 Cheektowaga, BNIA Drway & BNIA Terminal 12:20 PM San Diego, San Ysidro Transit Center $377 1 One-way 4 transfers - FlixBus · FlixBus+ ·
11:20 PM 93h50 Cheektowaga, BNIA Drway & BNIA Terminal 5:10 PM San Diego, Rail Ct / E San Ysidro Blvd (McDonald`s), CA $378 1 One-way 5 transfers
- · · ·
7:55 AM 61h50 Buffalo, NFTA Metro Center 5:45 PM San Diego, Congress Street (Old Town Park), CA $541 1 One-way 5 transfers - · · ·
7:55 AM 62h25 Buffalo, NFTA Metro Center 6:20 PM San Diego, San Ysidro Transit Center $392 1 One-way 5 transfers - · · ·
11:05 PM 64h45 Buffalo, NFTA Metro Center 11:50 AM San Diego, Congress Street (Old Town Park), CA $393 1 One-way 5 transfers - · · ·
11:05 PM 65h15 Buffalo, NFTA Metro Center 12:20 PM San Diego, San Ysidro Transit Center $253 1 One-way 5 transfers - · · ·
7:55 AM 66h20 Buffalo, NFTA Metro Center 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA $539 1 One-way 5 transfers
Journey information
Overview: Bus from Buffalo, NY to San Diego, CA
USAUSA
Buses from Buffalo, NY to San Diego, CA run on average 9 times per day, taking around 59h 41m. Cheap bus tickets for this journey start at $207 but you can travel from only $112 by flight.
The earliest bus runs at 06:45, the last at 23:20. The fastest bus covers the 2183 miles (3514 km) distance in 52h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $112
Plan this route
Journey facts
- Distance2183 miles (3514 km)
- Average bus duration59h 41m
- Cheapest ticket price$207
- Buses per day9
- Fastest bus52h 55m
- First bus6:45 AM
- Last bus11:20 PM
- Cheapest MonthJun
- Cheapest DaySat
- High SeasonJul - Sep
- Low SeasonJan - Mar
- Best time to book28 days
Understand & plan this route
Explore this journey
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $112
Frequently asked questions about your Buffalo, NY to San Diego, CA trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Buffalo, NY to San Diego, CA.
Cheap bus tickets from Buffalo, NY to San Diego, CA can start from as little as $207 when you book in advance. The average bus ticket price for Buffalo, NY to San Diego, CA is $309 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Buffalo, NY to San Diego, CA leaves at 6:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Buffalo, NY to San Diego, CA leaves at 11:20 PM.
There are 9 buses a day from Buffalo, NY to San Diego, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
Buffalo, NY to San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:20AM | Arrival Time 05:15AM | Duration 96h55 | Departure days Sun | Cheapest price $258 |
Operator Greyhound | Departure Time 07:55AM | Arrival Time 05:45PM | Duration 61h50 | Departure days Tue, Fri | Cheapest price $227 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 06:20PM | Duration 82h30 | Departure days Tue | Cheapest price $224 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 10:15PM | Duration 85h10 | Departure days Fri | Cheapest price $360 |
Operator Barons Bus | Departure Time 02:20PM | Arrival Time 05:25AM | Duration 63h05 | Departure days Wed | Cheapest price $733 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 05:10PM | Duration 100h30 | Departure days Tue | Cheapest price $235 |
Operator Greyhound | Departure Time 09:20PM | Arrival Time 01:10AM | Duration 75h50 | Departure days Thu, Sun | Cheapest price $243 |
Operator Greyhound | Departure Time 11:05PM | Arrival Time 05:10PM | Duration 70h05 | Departure days Tue, Fri | Cheapest price $226 |
Operator Greyhound | Departure Time 11:20PM | Arrival Time 11:45AM | Duration 88h25 | Departure days Fri | Cheapest price $377 |
Live departures
Buffalo, NY to San Diego, CA bus times
The table below shows live departures for Buffalo, NY to San Diego, CA buses for today, Thursday, October 29. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 9:20 PM Buffalo, NY | 75h50 | 1:10 AM San Diego, CA | 0 transfersDirect | |
| Friday, October 30 | |||||
| · · · | 7:55 AM Buffalo, NFTA Metro Center | 66h20 | 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 5 transfers | |
| · · · | 7:55 AM Buffalo, NFTA Metro Center | 61h50 | 5:45 PM San Diego, Congress Street (Old Town Park), CA | 5 transfers | |
| · · · | 7:55 AM Buffalo, NFTA Metro Center | 62h25 | 6:20 PM San Diego, San Ysidro Transit Center | 5 transfers | |
| FlixBus · FlixBus+ · | 1:05 PM Cheektowaga, BNIA Drway & BNIA Terminal | 85h10 | 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 4 transfers | |
| FlixBus · FlixBus+ · | 1:05 PM Cheektowaga, BNIA Drway & BNIA Terminal | 81h15 | 6:20 PM San Diego, San Ysidro Transit Center | 4 transfers | |
| FlixBus · FlixBus+ · | 1:05 PM Cheektowaga, BNIA Drway & BNIA Terminal | 80h40 | 5:45 PM San Diego, Congress Street (Old Town Park), CA | 4 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Buffalo, NY to San Diego, CA buses with Omio?
Greyhound operates all buses services from Buffalo, NY to San Diego, CA.
Omio is an official ticket reseller for all your travel options from Buffalo, NY to San Diego, CA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Buffalo, NY to San Diego, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Buffalo, NY to San Diego, CA.
Bus companies
Bus companies from Buffalo, NY to San Diego, CA
Buses from Buffalo, NY to San Diego, CA with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
52h 55m
Cheapest Greyhound Price
$207
Greyhound frequency
9 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Buffalo, NY and San Diego, CA
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Buffalo, NY to San Diego, CA, you can count on Greyhound for the best way to get you to San Diego, CA. You can also check all possible bus companies who offer a service between Buffalo, NY and San Diego, CA and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Buffalo, NY to San Diego, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Buffalo, NY to San Diego, CA for bus company Greyhound.
Whether you can cancel your bus ticket from Buffalo, NY to San Diego, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Buffalo, NY to San Diego, CA.
Yes, the following luggage options are included when booking a bus ticket from Buffalo, NY to San Diego, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Buffalo, NY to San Diego, CA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Buffalo, NY to San Diego, CA.
You can reserve your seat on the bus from Buffalo, NY to San Diego, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Buffalo, NY to San Diego, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Buffalo, NY to San Diego, CA with the following bus company: Greyhound.
Complete guide to San Diego, CA
Things to do in San Diego, CA
Discover the best of San Diego, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego, CA trip today.
- Must visit
Museum of Contemporary Art San Diego
Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.
- Must visit
USS Midway Museum
Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.
- Must visit
Balboa Park
Balboa Park is San Diego's grand cultural park, packed with gardens, architecture, museums, and walkable plazas worth lingering in.
- Must visit
Gaslamp Quarter
Historic Gaslamp Quarter offers Victorian-era streets, nightlife energy, and preserved downtown architecture for an atmospheric walk.
- Must visit
La Jolla Cove
Dramatic seaside cliffs and walking paths in La Jolla, famous for waves, sea lions, and sweeping Pacific views.
Fish Taco
A San Diego staple: grilled fish in a soft tortilla with cabbage, crema, and salsa. Popularized by Baja influence and coastal seafood culture.
California Burrito
French fries, carne asada, cheese, guacamole, and crema wrapped in a flour tortilla. A late-night local favorite born in San Diego taquerias.
- Gluten-free
Sea Urchin (Uni)
Fresh local sea urchin served raw, prized for its rich, buttery taste. It reflects San Diego's access to Pacific seafood and sushi culture.
Sushi Ota
Celebrated sushi restaurant specializing in omakase and pristine seafood, including uni. Intimate, polished, and highly respected by locals.
Mitch's Seafood
Iconic casual seafood counter known for fish tacos, smoked fish, and harbor views. A classic stop for San Diego's Baja-inspired seafood style.
Juniper and Ivy
Refined fine-dining restaurant showcasing local seafood and seasonal California ingredients. Elegant room with one of the city's strongest reputations.
US Dollar ($)
San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a mid-range meal.
- Fine dining
- $75+ per person for upscale dining.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.
Plan your visit to San Diego, CA
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Diego, CA.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Diego, CA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like beaches, public transportation, and popular tourist spots such as the Gaslamp Quarter and Old Town. Common scams include overpriced parking fees and unauthorized ticket sellers near attractions. Staying aware of surroundings, securing belongings, and using official transportation services help reduce risks. Additionally, travelers should avoid isolated areas at night and be mindful of local traffic laws when using scooters or bikes.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Buffalo, NY to San Diego, CA
Find answers to the most common questions about traveling from Buffalo, NY to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between Buffalo, NY and San Diego, CA including taking a train, bus, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Buffalo, NY to San Diego, CA
Most Buffalo, NY to San Diego, CA buses use the Cheektowaga, BNIA Drway & BNIA Terminal to San Diego, Congress Street (Old Town Park) station pair, with some services arriving at San Diego, San Ysidro Transit Center. Use this guide to compare Buffalo, NY and San Diego, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Buffalo
Arrival bus stations in San Diego
Cheektowaga, BNIA Drway & BNIA Terminal
City-centre transport
Getting to Cheektowaga, BNIA Drway & BNIA Terminal from Buffalo city centre
BusAdt N809 · 10m · $8
24, 78 · 31m · $3 · every ~4 min
24, 78 · 46m · $3 · every ~4 min
Buffalo, NFTA Metro CenterBuffalo, NY, USA
City-centre transport
Getting to Buffalo, NFTA Metro Center from Buffalo city centre
TRUE
Buffalo, NFTA Metro Center bus station facilities and services
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Tickets and information
Ticket office support is available at Buffalo, NFTA Metro Center.
Parking, taxis and toilets
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Which San Diego, CA station do buses from Buffalo, NY arrive at?
Buses from Buffalo, NY to San Diego, CA most often arrive at San Diego, Congress Street (Old Town Park). Some services arrive at San Diego, San Ysidro Transit Center, so check your ticket before travel to confirm your San Diego, CA arrival station.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USA
City-centre transport
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 20m · $2
83 · 26m · $6
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min
San Diego, Congress Street (Old Town Park) bus station facilities and services
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Tickets and information
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Parking, taxis and toilets
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USA
City-centre transport
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 25m · $3
910 · 41m · $6
TramBlue · 41m · $17 · every ~14 min
Blue · 43m · $17 · every ~14 min
San Diego, San Ysidro Transit Center bus station facilities and services
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food eateries located nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Tickets and information
Ticket office support is available at San Diego, San Ysidro Transit Center.
Parking, taxis and toilets
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
San Diego, West Harbor Drive (The Headquarters at Seaport District)W Harbor Dr, San Diego, CA, USA
City-centre transport
Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
TRUE
San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are in the area.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Tickets and information
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Parking, taxis and toilets
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
Most popular bus connections from Buffalo, NY
Most popular buses to and from San Diego, CA and Buffalo, NY
Most popular bus connections to San Diego, CA
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