- Must visit
San Diego Museum of Art
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
Cheapest price on Sep 16
€194
Average ticket price on Sep 16
€194
Fastest journey on Sep 16
2 d 21 h 40 m
Average journey duration on Sep 16
2 d 21 h 40 m
Buses on Sep 16
1
Distance
3514 km
The best way to find a cheap bus ticket from Buffalo, NY to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to San Diego, CA will cost around €194 if you buy it on the day, but the cheapest tickets can be found for only €194.
On Wed, Sep 16, we found 1 buses from Buffalo, NY to San Diego, CA, including 1 direct services.
On Wed, Sep 16 the direct buses cover the 3514 km distance in an average of 2 d 21 h 40 m but if you time it right, some buses will get you there in just 2 d 21 h 40 m .
On Wed, Sep 16 the slowest buses will take 2 d 21 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from Buffalo, NY to San Diego, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €259 For those with little time, consider booking a flight, which has an average total journey time of 9h 24m. Average ticket prices depend on the travel mode: a bus costs an average of €259, while a flight costs an average of €544.
Distance: 2183 miles (3514 km)
| Bus | Most popular Flight | Train |
|---|---|---|
€259 Average price Cheapest | €544 Average price | |
60h 5m Average total duration 59h 35m Onboard + 30m Additional time* | 9h 24m Average total duration Fastest 7h 24m Onboard + 2h 0m Additional time* | |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Buffalo, NY to San Diego, CA:
A bus is €285 less than a flight for this route with tickets for a flight from Buffalo, NY to San Diego, CA costing on average €544.
Other travel options to San Diego, CA take longer:
Bus takes on average 59h 35m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:05AM | Arrival Time 12:45AM | Duration 69h40 | Departure days Wed | Cheapest price €194 |
Operator Greyhound | Departure Time 04:20AM | Arrival Time 05:15AM | Duration 96h55 | Departure days Sun | Cheapest price €216 |
Operator Barons Bus | Departure Time 02:20PM | Arrival Time 05:25AM | Duration 63h05 | Departure days Wed, Fri | Cheapest price €616 |
Operator Greyhound | Departure Time 09:20PM | Arrival Time 01:10AM | Duration 75h50 | Departure days Thu, Sun | Cheapest price €204 |
The table below shows live departures for Buffalo, NY to San Diego, CA buses for tomorrow, Tuesday, September 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:05 AM Buffalo, NY | 69h40 | 12:45 AM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Buffalo, NY to San Diego, CA run on average 9 times per day, taking around 59h 35m. Cheap bus tickets for this journey start at €210 if you book in advance.
The earliest bus runs at 06:45, the last at 23:20. The fastest bus covers the 2183 miles (3514 km) distance in 52h 55m.
Distance 2183 miles (3514 km) |
Average bus duration 59h 35m |
Cheapest ticket price €210 |
Buses per day 9 |
Fastest bus 52h 55m |
First bus 6:45 AM |
Last bus 11:20 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 28 days |
Discover the best of San Diego, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego, CA trip today.
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.
Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.
Balboa Park is San Diego's grand cultural park, packed with gardens, architecture, museums, and walkable plazas worth lingering in.
Historic Gaslamp Quarter offers Victorian-era streets, nightlife energy, and preserved downtown architecture for an atmospheric walk.
Dramatic seaside cliffs and walking paths in La Jolla, famous for waves, sea lions, and sweeping Pacific views.
A San Diego staple: grilled fish in a soft tortilla with cabbage, crema, and salsa. Popularized by Baja influence and coastal seafood culture.
French fries, carne asada, cheese, guacamole, and crema wrapped in a flour tortilla. A late-night local favorite born in San Diego taquerias.
Fresh local sea urchin served raw, prized for its rich, buttery taste. It reflects San Diego's access to Pacific seafood and sushi culture.
Celebrated sushi restaurant specializing in omakase and pristine seafood, including uni. Intimate, polished, and highly respected by locals.
Iconic casual seafood counter known for fish tacos, smoked fish, and harbor views. A classic stop for San Diego's Baja-inspired seafood style.
Refined fine-dining restaurant showcasing local seafood and seasonal California ingredients. Elegant room with one of the city's strongest reputations.
San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.
Find answers to the most common questions about traveling from Buffalo, NY to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

Most Buffalo, NY to San Diego, CA buses use the Cheektowaga, BNIA Drway & BNIA Terminal to San Diego, Congress Street (Old Town Park) station pair, with some services arriving at San Diego, West Harbor Drive (The Headquarters at Seaport District). Use this guide to compare Buffalo, NY and San Diego, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Ticket office support is available at Buffalo, NFTA Metro Center.
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several dining options nearby.
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several dining options are in the area.
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food eateries located nearby.
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Ticket office support is available at San Diego, San Ysidro Transit Center.
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
Here are some other resources that might have the information you need