Travel Information
Compare train, bus, and flight for Buffalo, NY to San Diego, CA
Omio recommends booking the train as it is the most popular option from Buffalo, NY to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €218. For those with little time consider booking a flight which can get you there in 8h 40m. The ticket price range depends on the travel mode: a bus costs an average of €218, and a train costs an average of €286.
Distance: 2183 miles (3514 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€258 Average price Cheapest | €381 Average price | €369 Average price |
79h 23m Average total duration 78h 53m Onboard + 30m Additional time* | 63h 58m Average total duration 63h 28m Onboard + 30m Additional time* | 11h 40m Average total duration Fastest 8h 40m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Buffalo, NY to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Buffalo, NY to San Diego, CA
Buses from Buffalo, NY to San Diego, CA run on average 18 times per day, taking around 78h 53m. Cheap bus tickets for this journey start at $273 (€218) if you book in advance.
The earliest bus runs at 00:55, the last at 23:20. The fastest bus covers the 2183 miles (3514 km) distance in 75h 25m.
Distance 2183 miles (3514 km) |
Average bus duration 78h 53m |
Cheapest ticket price $273 (€218) |
Buses per day 18 |
Fastest bus 75h 25m |
First bus 00:55 |
Last bus 23:20 |
FAQs: Bus from Buffalo, NY to San Diego, CA
Find answers to the most common questions about traveling from Buffalo, NY to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- Enjoy a harbor cruise for stunning views of the skyline and naval ships
- Hike the scenic trails at Torrey Pines State Natural Reserve
- Visit the Birch Aquarium to learn about marine life and ocean conservation
- Experience the thrill of a whale watching tour off the coast.
To find the cheapest bus tickets for your trip from Buffalo, NY to San Diego, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
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Popular bus stations from Buffalo, NY to San Diego, CA
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