- Must visit
San Diego Museum of Art
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
Cheapest price
$265
Average price
$265
Fastest journey
4 d 55 m
Average duration
4 d 55 m
Buses per day
1
Distance
3514 km
The best way to find a cheap bus ticket from Buffalo, NY to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to San Diego, CA will cost around $265 if you buy it on the day, but the cheapest tickets can be found for only $265.
Of the 1 buses that leave Buffalo, NY for San Diego, CA on Sun, Aug 02, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Aug 02 the direct buses cover the 3514 km distance in an average of 4 d 55 m but if you time it right, some buses will get you there in just 4 d 55 m .
On Sun, Aug 02 the slowest buses will take 4 d 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Buffalo, NY to San Diego, CA among Omio's users. If you are prioritising price take the train with prices starting from $260. For those with little time consider booking a flight which can get you there in 9h 10m. The ticket price range depends on the travel mode: a train costs an average of $260, and a flight costs an average of $159.
Distance: 2183 miles (3514 km)
Most popular Bus | Train | Flight |
|---|---|---|
$280 Average price | $262 Average price Cheapest | $330 Average price |
80h 4m Average total duration 79h 34m Onboard + 30m Additional time* | 63h 58m Average total duration 63h 28m Onboard + 30m Additional time* | 12h 10m Average total duration Fastest 9h 10m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Buffalo, NY to San Diego, CA:
A train is $18 (€15) less than a bus for this route with tickets for a bus from Buffalo, NY to San Diego, CA costing on average $280 (€228).
A train is $68 (€56) less than a flight for this route with tickets for a flight from Buffalo, NY to San Diego, CA costing on average $330 (€269).
Other travel options to San Diego, CA take longer:
Train takes on average 63h 28m.
Bus takes on average 79h 34m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:05AM | Arrival Time 12:45AM | Duration 69h40 | Departure days Wed | Cheapest price $238 |
Operator Greyhound | Departure Time 04:20AM | Arrival Time 05:15AM | Duration 96h55 | Departure days Sun | Cheapest price $265 |
Operator Barons Bus | Departure Time 02:20PM | Arrival Time 05:25AM | Duration 63h05 | Departure days Wed, Fri | Cheapest price $756 |
Operator Greyhound | Departure Time 09:20PM | Arrival Time 01:10AM | Duration 75h50 | Departure days Thu, Sun | Cheapest price $250 |
The table below shows live departures for Buffalo, NY to San Diego, CA buses for today, Friday, July 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:20 PM Buffalo, NY | 63h05 | 5:25 AM San Diego, CA | 3 transfers | |
| Saturday, August 1 | |||||
![]() | 4:20 AM Buffalo, NY | 96h55 | 5:15 AM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Buffalo, NY to San Diego, CA run on average 12 times per day, taking around 79h 34m. Cheap bus tickets for this journey start at $238 (€194) but you can travel from only $159 (€130) by flight.
The earliest bus runs at 06:45, the last at 23:20. The fastest bus covers the 2183 miles (3514 km) distance in 69h 40m.
Distance 2183 miles (3514 km) |
Average bus duration 79h 34m |
Cheapest ticket price $238 (€194) |
Buses per day 12 |
Fastest bus 69h 40m |
First bus 6:45 AM |
Last bus 11:20 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Apr - Jun |
Best time to book 28 days |
Discover the best of San Diego, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego, CA trip today.
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.
Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.
Balboa Park is San Diego's grand cultural park, packed with gardens, architecture, museums, and walkable plazas worth lingering in.
Historic Gaslamp Quarter offers Victorian-era streets, nightlife energy, and preserved downtown architecture for an atmospheric walk.
Dramatic seaside cliffs and walking paths in La Jolla, famous for waves, sea lions, and sweeping Pacific views.
A San Diego staple: grilled fish in a soft tortilla with cabbage, crema, and salsa. Popularized by Baja influence and coastal seafood culture.
French fries, carne asada, cheese, guacamole, and crema wrapped in a flour tortilla. A late-night local favorite born in San Diego taquerias.
Fresh local sea urchin served raw, prized for its rich, buttery taste. It reflects San Diego's access to Pacific seafood and sushi culture.
Celebrated sushi restaurant specializing in omakase and pristine seafood, including uni. Intimate, polished, and highly respected by locals.
Iconic casual seafood counter known for fish tacos, smoked fish, and harbor views. A classic stop for San Diego's Baja-inspired seafood style.
Refined fine-dining restaurant showcasing local seafood and seasonal California ingredients. Elegant room with one of the city's strongest reputations.
San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.
Find answers to the most common questions about traveling from Buffalo, NY to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

Most Buffalo, NY to San Diego, CA buses use the Cheektowaga, BNIA Drway & BNIA Terminal to San Diego, Congress Street (Old Town Park) station pair, with some services arriving at San Diego, West Harbor Drive (The Headquarters at Seaport District). Use this guide to compare Buffalo, NY and San Diego, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need