- Must visit
Mint Museum Uptown
Major Uptown museum for European, American, and contemporary art. Its collection and architecture make it Charlotte's top fine-arts stop.
Cheapest price on Sep 18
$147
Average ticket price on Sep 18
$173
Fastest journey on Sep 18
22 h 15 m
Average journey duration on Sep 18
23 h 8 m
Buses on Sep 18
10
Distance
868 km
The best way to find a cheap bus ticket from Buffalo, NY to Charlotte, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to Charlotte, NC will cost around $173 if you buy it on the day, but the cheapest tickets can be found for only $147.
It's difficult to get from Buffalo, NY to Charlotte, NC without transferring at least once.
FlixBus+
FlixBus+
+
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus+
FlixBus+
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus+
Omio recommends booking the bus as it is the most popular option from Buffalo, NY to Charlotte, NC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $171 For those with little time, consider booking a flight, which has an average total journey time of 6h 5m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.3 - 0.8kg. Average ticket prices depend on the travel mode: a bus costs an average of $171, while a flight costs an average of $648.
Distance: 539 miles (868 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$171 Average price Cheapest | $430 Average price | $648 Average price | $145 Average price (fuel + tolls) |
22h 36m Average total duration 22h 6m Onboard + 30m Additional time* | 21h 26m Average total duration 20h 56m Onboard + 30m Additional time* | 6h 5m Average total duration Fastest 4h 5m Onboard + 2h 0m Additional time* | 10h 6m Average total duration (door-to-door) |
0.9 - 2.2kg CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | 2.6 - 5.2kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Buffalo, NY to Charlotte, NC:
A bus is $259 less than a train for this route with tickets for a train from Buffalo, NY to Charlotte, NC costing on average $430.
A bus is $477 less than a flight for this route with tickets for a flight from Buffalo, NY to Charlotte, NC costing on average $648.
Other travel options to Charlotte, NC take longer:
Train takes on average 20h 56m.
Bus takes on average 22h 6m.
Tickets start at around $171 compared to roughly $145 in fuel and tolls — a saving of about $-25.83. The journey takes 22h 6m versus 10h 6m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 12:45AM | Duration 24h25 | Departure days Mon, Sun | Cheapest price $98 |
Operator Greyhound | Departure Time 03:30AM | Arrival Time 03:55AM | Duration 24h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $112 |
Operator Greyhound | Departure Time 03:50AM | Arrival Time 03:55AM | Duration 24h05 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 05:30AM | Arrival Time 06:30AM | Duration 25h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 06:30AM | Duration 24h45 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $90 |
Operator Greyhound | Departure Time 10:30AM | Arrival Time 09:05AM | Duration 22h35 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $97 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 09:05AM | Duration 22h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $96 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 07:40PM | Duration 30h55 | Departure days Tue, Wed | Cheapest price $101 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 11:50AM | Duration 23h00 | Departure days Sat | Cheapest price $329 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 05:40PM | Duration 28h35 | Departure days Mon, Thu, Fri, Sun | Cheapest price $116 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 07:40PM | Duration 30h35 | Departure days Tue, Wed | Cheapest price $101 |
Operator Greyhound | Departure Time 03:30PM | Arrival Time 02:30PM | Duration 23h00 | Departure days Sat | Cheapest price $181 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 05:40PM | Duration 24h20 | Departure days Mon, Thu, Fri, Sun | Cheapest price $98 |
Operator Greyhound | Departure Time 11:00PM | Arrival Time 03:55AM | Duration 28h55 | Departure days Tue | Cheapest price $120 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 12:45AM | Duration 25h45 | Departure days Wed, Thu, Fri | Cheapest price $150 |
Operator Greyhound | Departure Time 11:20PM | Arrival Time 03:55AM | Duration 28h35 | Departure days Mon, Tue | Cheapest price $101 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 12:45AM | Duration 25h25 | Departure days Wed, Thu, Fri, Sun | Cheapest price $116 |
Operator Greyhound | Departure Time 11:59PM | Arrival Time 03:55AM | Duration 27h56 | Departure days Mon | Cheapest price $99 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 12:45AM | Duration 24h46 | Departure days Sun | Cheapest price $117 |
The table below shows live departures for Buffalo, NY to Charlotte, NC buses for tomorrow, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 3:30 AM Buffalo, NFTA Metro Center | 24h25 | 3:55 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 3:50 AM Cheektowaga, BNIA Drway & BNIA Terminal | 24h05 | 3:55 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus | 5:30 AM Buffalo, NFTA Metro Center | 23h30 | 5:00 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus | 5:45 AM Cheektowaga, BNIA Drway & BNIA Terminal | 23h15 | 5:00 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 10:30 AM Buffalo, NFTA Metro Center | 22h35 | 9:05 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 10:50 AM Cheektowaga, BNIA Drway & BNIA Terminal | 22h15 | 9:05 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:05 PM Cheektowaga, BNIA Drway & BNIA Terminal | 28h35 | 5:40 PM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
FlixBus · FlixBus+![]() | 5:20 PM Buffalo, NFTA Metro Center | 24h20 | 5:40 PM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Buffalo, NY to Charlotte, NC run on average 12 times per day, taking around 22h 6m. Cheap bus tickets for this journey start at $98 if you book in advance.
The earliest bus runs at 00:55, the last at 23:55. The fastest bus covers the 539 miles (868 km) distance in 20h 10m.
Distance 539 miles (868 km) |
Average bus duration 22h 6m |
Cheapest ticket price $98 |
Buses per day 12 |
Fastest bus 20h 10m |
First bus 12:55 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 35 days |
Discover the best of Charlotte, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charlotte, NC trip today.
Major Uptown museum for European, American, and contemporary art. Its collection and architecture make it Charlotte's top fine-arts stop.
Leading center for African American arts and culture, featuring exhibitions, performances, and powerful stories from Charlotte and beyond.
Regional science museum with hands-on exhibits, live demonstrations, and an IMAX Dome. Great for families and curious adults alike.
Charlotte's central business district mixes museums, plazas, public art, and skyline views. Essential for first-time visitors exploring the city core.
Creative historic district packed with murals, music venues, design shops, and converted mills. Ideal for art, walking, and local culture.
Trendy neighborhood known for rail-trail walking, street art, breweries, and restored industrial spaces. One of Charlotte's liveliest areas.
Slow-smoked chopped or pulled pork with a tangy vinegar sauce, a Carolina barbecue staple widely loved across Charlotte.
Smoky pit-cooked pork shoulder finished with mustard-based sauce, reflecting South Carolina influence common in Charlotte.
Deep-fried catfish, often served with hush puppies and slaw. It is a classic Southern comfort dish popular in the Charlotte region.
Historic barbecue spot famed for Carolina chopped pork, red slaw, and old-school Southern atmosphere.
Lively Southern dining room serving fried chicken, biscuits, shrimp and grits, and regional cocktails in South End.
Refined Southern restaurant in Uptown known for shrimp and grits, local ingredients, and an elegant modern setting.
Moderate for a major U.S. city. Hotels and dining are mid-priced, transit is affordable, and attractions often cost less than in larger hubs like New York or San Francisco.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is provided.
Find answers to the most common questions about traveling from Buffalo, NY to Charlotte, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charlotte, NC, this guide helps you travel smarter and with confidence.

Most Buffalo, NY to Charlotte, NC buses use the Cheektowaga, BNIA Drway & BNIA Terminal to Charlotte, W 4th St (Greyhound Bus Station) station pair. Use this guide to compare Buffalo, NY and Charlotte, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Ticket office support is available at Buffalo, NFTA Metro Center.
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Charlotte, W 4th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Charlotte, W 4th St (Greyhound Bus Station). ATMs are available at Charlotte, W 4th St (Greyhound Bus Station).
Ticket office support is available at Charlotte, W 4th St (Greyhound Bus Station).
Available at Charlotte, W 4th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charlotte, W 4th St (Greyhound Bus Station): The station is wheelchair accessible.
Here are some other resources that might have the information you need