- Must visit
Mint Museum Uptown
Major art museum in Center City with American, contemporary, and craft collections in a modern high-rise setting.
Cheapest price
$134
Average price
$151
Fastest journey
22 h 15 m
Average duration
23 h 8 m
Buses per day
15
Distance
868 km
The best way to find a cheap bus ticket from Buffalo, NY to Charlotte, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to Charlotte, NC will cost around $151 if you buy it on the day, but the cheapest tickets can be found for only $134.
It's difficult to get from Buffalo, NY to Charlotte, NC without transferring at least once.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus+
FlixBus+
FlixBus+
FlixBus+
FlixBus+
FlixBus · FlixBus
FlixBus · FlixBus
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Omio recommends booking the bus as it is the most popular option from Buffalo, NY to Charlotte, NC among Omio's users. If you are prioritising price take the bus with prices starting from $106. For those with little time consider booking a flight which can get you there in 2h 7m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of $106, and a flight costs an average of $336.
Distance: 539 miles (868 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$191 Average price Cheapest | $412 Average price | $410 Average price | $143 Average price (fuel + tolls) |
21h 33m Average total duration 21h 3m Onboard + 30m Additional time* | 5h 7m Average total duration Fastest 2h 7m Onboard + 3h 0m Additional time* | 20h 50m Average total duration 20h 20m Onboard + 30m Additional time* | 10h 6m Average total duration (door-to-door) |
0.9 - 2.2kg CO2 emissions | 2.6 - 5.2kg CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Buffalo, NY to Charlotte, NC:
A bus is $219 (€179) less than a train for this route with tickets for a train from Buffalo, NY to Charlotte, NC costing on average $410 (€336).
A bus is $221 (€181) less than a flight for this route with tickets for a flight from Buffalo, NY to Charlotte, NC costing on average $412 (€338).
Other travel options to Charlotte, NC take longer:
Train takes on average 20h 20m.
Bus takes on average 21h 3m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 12:45AM | Duration 24h25 | Departure days Everyday | Cheapest price $145 |
Operator Greyhound | Departure Time 03:30AM | Arrival Time 03:55AM | Duration 24h25 | Departure days Everyday | Cheapest price $138 |
Operator Greyhound | Departure Time 03:50AM | Arrival Time 03:55AM | Duration 24h05 | Departure days Everyday | Cheapest price $139 |
Operator FlixBus | Departure Time 05:30AM | Arrival Time 05:00AM | Duration 23h30 | Departure days Everyday | Cheapest price $134 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 05:00AM | Duration 23h15 | Departure days Everyday | Cheapest price $134 |
Operator Greyhound | Departure Time 10:30AM | Arrival Time 09:05AM | Duration 22h35 | Departure days Everyday | Cheapest price $135 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 09:05AM | Duration 22h15 | Departure days Everyday | Cheapest price $138 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 05:25PM | Duration 28h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $159 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 07:40PM | Duration 30h35 | Departure days Tue | Cheapest price $146 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 07:40PM | Duration 28h00 | Departure days Tue, Wed | Cheapest price $137 |
Operator Greyhound | Departure Time 05:20PM | Arrival Time 05:25PM | Duration 24h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $160 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 06:50AM | Duration 31h30 | Departure days Everyday | Cheapest price $156 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 12:45AM | Duration 24h46 | Departure days Everyday | Cheapest price $148 |
The table below shows live departures for Buffalo, NY to Charlotte, NC buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 10:30 AM Buffalo, NFTA Metro Center | 22h35 | 9:05 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 10:50 AM Cheektowaga, BNIA Drway & BNIA Terminal | 22h15 | 9:05 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:05 PM Cheektowaga, BNIA Drway & BNIA Terminal | 28h20 | 5:25 PM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
+ FlixBus · FlixBus | 5:20 PM Buffalo, NFTA Metro Center | 24h05 | 5:25 PM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:20 PM Cheektowaga, BNIA Drway & BNIA Terminal | 31h30 | 6:50 AM Charlotte, Freedom Drive (Planet Fitness), NC | 2 transfers | |
FlixBus · FlixBus | 11:20 PM Cheektowaga, BNIA Drway & BNIA Terminal | 25h25 | 12:45 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus | 11:59 PM Buffalo, NFTA Metro Center | 24h46 | 12:45 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:59 PM Buffalo, NFTA Metro Center | 30h51 | 6:50 AM Charlotte, Freedom Drive (Planet Fitness), NC | 2 transfers | |
| Saturday, June 20 | |||||
FlixBus · FlixBus | 12:20 AM Cheektowaga, BNIA Drway & BNIA Terminal | 24h25 | 12:45 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 3:30 AM Buffalo, NFTA Metro Center | 24h25 | 3:55 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 3:50 AM Cheektowaga, BNIA Drway & BNIA Terminal | 24h05 | 3:55 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:30 AM Buffalo, NFTA Metro Center | 25h20 | 6:50 AM Charlotte, Freedom Drive (Planet Fitness), NC | 2 transfers | |
FlixBus · FlixBus | 5:30 AM Buffalo, NFTA Metro Center | 23h30 | 5:00 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus | 5:45 AM Cheektowaga, BNIA Drway & BNIA Terminal | 23h15 | 5:00 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:45 AM Cheektowaga, BNIA Drway & BNIA Terminal | 25h05 | 6:50 AM Charlotte, Freedom Drive (Planet Fitness), NC | 2 transfers | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Buffalo, NY to Charlotte, NC run on average 11 times per day, taking around 21h 3m. Cheap bus tickets for this journey start at $106 (€86) if you book in advance.
The earliest bus runs at 00:55, the last at 23:55. The fastest bus covers the 539 miles (868 km) distance in 23h 0m.
Distance 539 miles (868 km) |
Average bus duration 21h 3m |
Cheapest ticket price $106 (€86) |
Buses per day 11 |
Fastest bus 23h 0m |
First bus 12:55 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Charlotte — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charlotte trip today.
Major art museum in Center City with American, contemporary, and craft collections in a modern high-rise setting.
Interactive museum celebrating NASCAR history, drivers, and racing culture; one of Charlotte's signature visitor attractions.
The original Mint Museum campus, known for decorative arts, fashion, and historic collections in a quieter setting.
One of Charlotte's best-known urban parks, with fountains, lawns, skyline views, and frequent social media exposure.
Large beloved park with trails, lake views, sports areas, and a strong local following for walks and picnics.
Trendy neighborhood known for rail-trail walking, murals, adaptive-reuse buildings, and strong popularity with younger visitors.
Slow-smoked pork shoulder, usually chopped or pulled and dressed with a tangy vinegar-based sauce. It is a signature Carolinas barbecue style widely loved in Charlotte.
Pork shoulder smoked over hardwood and served with a red slaw seasoned with barbecue dip. This Piedmont North Carolina tradition is common around Charlotte.
Crisp, seasoned chicken with deep Southern roots, often served with biscuits and sides. It is a staple comfort food across Charlotte and the Carolinas.
Established fine-dining restaurant in a historic house, known for elegant Continental cuisine, polished service, and a romantic atmosphere.
Stylish NoDa restaurant specializing in Southern small plates, fried chicken, biscuits, and cocktails in a busy, modern setting.
Popular barbecue restaurant known for smoked meats, brisket, ribs, and classic Southern sides in a lively, casual setting.
Moderate by U.S. standards. Hotels vary, while casual dining, coffee, and local transport are fairly manageable for most visitors.
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff a few USD, and round up for casual services.
Find answers to the most common questions about traveling from Buffalo, NY to Charlotte, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charlotte, NC, this guide helps you travel smarter and with confidence.

Most Buffalo, NY to Charlotte, NC buses use the Cheektowaga, BNIA Drway & BNIA Terminal to Charlotte, W 4th St (Greyhound Bus Station) station pair, with some services arriving at Charlotte, Freedom Drive (Planet Fitness). Use this guide to compare Buffalo, NY and Charlotte, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need