- Must visit
Mint Museum Uptown
Major Uptown museum for European, American, and contemporary art. Its collection and architecture make it Charlotte's top fine-arts stop.
Cheapest price
CHF90
Average price
CHF108
Fastest journey
22 h 15 m
Average duration
23 h 8 m
Buses per day
11
Distance
868 km
The best way to find a cheap bus ticket from Buffalo, NY to Charlotte, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to Charlotte, NC will cost around CHF108 if you buy it on the day, but the cheapest tickets can be found for only CHF90.
It's difficult to get from Buffalo, NY to Charlotte, NC without transferring at least once.
FlixBus+
FlixBus · FlixBus
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FlixBus · FlixBus
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FlixBus · FlixBus
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Buses from Buffalo, NY to Charlotte, NC run on average 11 times per day, taking around 21h 3m. Cheap bus tickets for this journey start at CHF86 if you book in advance.
The earliest bus runs at 00:55, the last at 23:55. The fastest bus covers the 539 miles (868 km) distance in 23h 0m.
Distance 539 miles (868 km) |
Average bus duration 21h 3m |
Cheapest ticket price CHF86 |
Buses per day 11 |
Fastest bus 23h 0m |
First bus 12:55 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Apr - Jun |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 12:45AM | Duration 24h25 | Departure days Everyday | Cheapest price CHF95 |
Operator Greyhound | Departure Time 03:30AM | Arrival Time 03:55AM | Duration 24h25 | Departure days Everyday | Cheapest price CHF110 |
Operator Greyhound | Departure Time 03:50AM | Arrival Time 03:55AM | Duration 24h05 | Departure days Everyday | Cheapest price CHF112 |
Operator FlixBus | Departure Time 05:30AM | Arrival Time 05:00AM | Duration 23h30 | Departure days Everyday | Cheapest price CHF84 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 05:00AM | Duration 23h15 | Departure days Everyday | Cheapest price CHF83 |
Operator Greyhound | Departure Time 10:30AM | Arrival Time 09:05AM | Duration 22h35 | Departure days Everyday | Cheapest price CHF86 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 09:05AM | Duration 22h15 | Departure days Everyday | Cheapest price CHF85 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 07:40PM | Duration 30h55 | Departure days Tue | Cheapest price CHF112 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 05:25PM | Duration 28h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price CHF102 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 07:40PM | Duration 30h35 | Departure days Tue | Cheapest price CHF111 |
Operator Greyhound | Departure Time 05:20PM | Arrival Time 05:25PM | Duration 24h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price CHF91 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 12:45AM | Duration 25h25 | Departure days Everyday | Cheapest price CHF90 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 12:45AM | Duration 24h46 | Departure days Everyday | Cheapest price CHF89 |
The table below shows live departures for Buffalo, NY to Charlotte, NC buses for today, Monday, August 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 1:05 PM Cheektowaga, BNIA Drway & BNIA Terminal | 28h20 | 5:25 PM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
+ FlixBus · FlixBus | 5:20 PM Buffalo, NFTA Metro Center | 24h05 | 5:25 PM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
FlixBus · FlixBus | 11:20 PM Cheektowaga, BNIA Drway & BNIA Terminal | 25h25 | 12:45 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus | 11:59 PM Buffalo, NFTA Metro Center | 24h46 | 12:45 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
| Tuesday, August 4 | |||||
FlixBus · FlixBus | 12:20 AM Cheektowaga, BNIA Drway & BNIA Terminal | 24h25 | 12:45 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 3:30 AM Buffalo, NFTA Metro Center | 24h25 | 3:55 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 3:50 AM Cheektowaga, BNIA Drway & BNIA Terminal | 24h05 | 3:55 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus | 5:30 AM Buffalo, NFTA Metro Center | 23h30 | 5:00 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus | 5:45 AM Cheektowaga, BNIA Drway & BNIA Terminal | 23h15 | 5:00 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 10:30 AM Buffalo, NFTA Metro Center | 22h35 | 9:05 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 10:50 AM Cheektowaga, BNIA Drway & BNIA Terminal | 22h15 | 9:05 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Charlotte, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charlotte, NC trip today.
Major Uptown museum for European, American, and contemporary art. Its collection and architecture make it Charlotte's top fine-arts stop.
Leading center for African American arts and culture, featuring exhibitions, performances, and powerful stories from Charlotte and beyond.
Regional science museum with hands-on exhibits, live demonstrations, and an IMAX Dome. Great for families and curious adults alike.
Charlotte's central business district mixes museums, plazas, public art, and skyline views. Essential for first-time visitors exploring the city core.
Creative historic district packed with murals, music venues, design shops, and converted mills. Ideal for art, walking, and local culture.
Trendy neighborhood known for rail-trail walking, street art, breweries, and restored industrial spaces. One of Charlotte's liveliest areas.
Slow-smoked chopped or pulled pork with a tangy vinegar sauce, a Carolina barbecue staple widely loved across Charlotte.
Smoky pit-cooked pork shoulder finished with mustard-based sauce, reflecting South Carolina influence common in Charlotte.
Deep-fried catfish, often served with hush puppies and slaw. It is a classic Southern comfort dish popular in the Charlotte region.
Historic barbecue spot famed for Carolina chopped pork, red slaw, and old-school Southern atmosphere.
Lively Southern dining room serving fried chicken, biscuits, shrimp and grits, and regional cocktails in South End.
Refined Southern restaurant in Uptown known for shrimp and grits, local ingredients, and an elegant modern setting.
Moderate for a major U.S. city. Hotels and dining are mid-priced, transit is affordable, and attractions often cost less than in larger hubs like New York or San Francisco.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is provided.
Find answers to the most common questions about traveling from Buffalo, NY to Charlotte, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charlotte, NC, this guide helps you travel smarter and with confidence.

Most Buffalo, NY to Charlotte, NC buses use the Cheektowaga, BNIA Drway & BNIA Terminal to Charlotte, W 4th St (Greyhound Bus Station) station pair, with some services arriving at Charlotte, Freedom Drive (Planet Fitness). Use this guide to compare Buffalo, NY and Charlotte, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need