The cheapest and fastest buses from Buffalo, NY to Charlotte, NC
Cheapest price
$120
Average price
$162
Fastest journey
21 h 40 m
Average duration
1 d 43 m
Buses per day
2
Distance
868 km
The best way to find a cheap bus ticket from Buffalo, NY to Charlotte, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to Charlotte, NC will cost around $162 if you buy it on the day, but the cheapest tickets can be found for only $120.
Of the 2 buses that leave Buffalo, NY for Charlotte, NC on Wed, Feb 04, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Feb 04 the direct buses cover the 868 km distance in an average of 1 d 43 m but if you time it right, some buses will get you there in just 21 h 40 m .
On Wed, Feb 04 the slowest buses will take 1 d 3 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, and flight for Buffalo, NY to Charlotte, NC
Omio recommends booking the train as it is the most popular option from Buffalo, NY to Charlotte, NC among Omio's users. If you are prioritising price take the bus with prices starting from €95. For those with little time consider booking a flight which can get you there in 1h 58m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of €95, and a flight costs an average of €275.
Distance: 539 miles (868 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€117 Average price Cheapest | €277 Average price | €293 Average price |
22h 38m Average total duration 22h 8m Onboard + 30m Additional time* | 20h 50m Average total duration 20h 20m Onboard + 30m Additional time* | 4h 58m Average total duration Fastest 1h 58m Onboard + 3h 0m Additional time* |
0.9 - 2.2kg CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | 2.6 - 5.2kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Buffalo, NY to Charlotte, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:50AM | Arrival Time 09:30AM | Duration 25h40 | Departure days Tue | Cheapest price $207 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 09:30AM | Duration 24h30 | Departure days Tue | Cheapest price $208 |
Operator Greyhound | Departure Time 03:00PM | Arrival Time 07:40PM | Duration 28h40 | Departure days Tue | Cheapest price $210 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 04:40PM | Duration 25h20 | Departure days Tue | Cheapest price $208 |
Operator Greyhound | Departure Time 11:20PM | Arrival Time 03:55AM | Duration 28h35 | Departure days Tue | Cheapest price $211 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 06:50AM | Duration 31h30 | Departure days Tue | Cheapest price $206 |
Operator Greyhound | Departure Time 11:59PM | Arrival Time 03:55AM | Duration 27h56 | Departure days Tue | Cheapest price $207 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 06:50AM | Duration 30h51 | Departure days Tue | Cheapest price $208 |
Live departures
Buffalo, NY to Charlotte, NC bus times
The table below shows live departures for Buffalo, NY to Charlotte, NC buses for tomorrow, Wednesday, February 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 4:20 AM Cheektowaga, BNIA Drway & BNIA Terminal | 28h35 | 8:55 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:20 AM Cheektowaga, BNIA Drway & BNIA Terminal | 31h30 | 11:50 AM Charlotte, Freedom Drive (Planet Fitness), NC | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:59 AM Buffalo, NFTA Metro Center | 30h51 | 11:50 AM Charlotte, Freedom Drive (Planet Fitness), NC | 2 transfers | |
FlixBus · FlixBus+![]() | 4:59 AM Buffalo, NFTA Metro Center | 27h56 | 8:55 AM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
![]() | 2:50 PM Buffalo, NY | 21h40 | 12:30 PM Charlotte, NC | 0 transfersDirect | |
![]() | 5:45 PM Buffalo, NY | 27h45 | 9:30 PM Charlotte, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Buffalo, NY to Charlotte, NC by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 04
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Why should you book Buffalo, NY to Charlotte, NC buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Barons Bus to find the best option for your trip from Buffalo, NY to Charlotte, NC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Buffalo, NY to Charlotte, NC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Buffalo, NY to Charlotte, NC.
Journey information
Overview: Bus from Buffalo, NY to Charlotte, NC
Buses from Buffalo, NY to Charlotte, NC run on average 13 times per day, taking around 22h 8m. Cheap bus tickets for this journey start at $120 (€95) if you book in advance.
The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 539 miles (868 km) distance in 21h 40m.
Distance 539 miles (868 km) |
Average bus duration 22h 8m |
Cheapest ticket price $120 (€95) |
Buses per day 13 |
Fastest bus 21h 40m |
First bus 00:20 |
Last bus 23:55 |
Bus providers: Greyhound, Barons Bus from Buffalo, NY to Charlotte, NCYou can travel by bus between Buffalo, NY to Charlotte, NC with Greyhound, Barons Bus for as low as $120 (€95). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Barons Bus
FAQs: Bus from Buffalo, NY to Charlotte, NC
Find answers to the most common questions about traveling from Buffalo, NY to Charlotte, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charlotte, NC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- NASCAR Hall of Fame, an interactive museum dedicated to the history and heritage of NASCAR with exhibits and simulators
- Discovery Place Science, a hands-on science and technology museum featuring interactive exhibits and an IMAX theater
- Freedom Park, a 98-acre park offering walking trails, sports fields, and a picturesque lake
- Mint Museum Uptown, an art museum showcasing American, contemporary, and European art collections
- Levine Museum of the New South, focusing on post-Civil War Southern history and culture.
- Carowinds, a large amusement park featuring roller coasters and a water park
- U.S. National Whitewater Center, offering outdoor activities like whitewater rafting, kayaking, and rock climbing
- NoDa, Charlotte's historic arts and entertainment district with galleries, music venues, and unique dining experiences
- Charlotte Motor Speedway, hosting NASCAR races and other motorsport events
- Billy Graham Library, a museum and library dedicated to the life and legacy of the famous evangelist.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Buffalo, NY to Charlotte, NC
Most popular bus connections from Buffalo, NY
More options for your journey from Buffalo, NY to Charlotte, NC
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