The cheapest and fastest buses from Buffalo, NY to San Antonio, TX
Cheapest price
$137
Average price
$283
Fastest journey
1 d 16 h 55 m
Average duration
2 d 7 h 43 m
Buses per day
3
Distance
2301 km
The best way to find a cheap bus ticket from Buffalo, NY to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to San Antonio, TX will cost around $283 if you buy it on the day, but the cheapest tickets can be found for only $137.
Of the 3 buses that leave Buffalo, NY for San Antonio, TX on Tue, Mar 03, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 03 the direct buses cover the 2301 km distance in an average of 2 d 7 h 43 m but if you time it right, some buses will get you there in just 1 d 16 h 55 m .
On Tue, Mar 03 the slowest buses will take 3 d 1 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare train, bus, and flight for Buffalo, NY to San Antonio, TX
Omio recommends booking the flight as it is the most popular option from Buffalo, NY to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from $137. For those with little time consider booking a flight which can get you there in 4h 48m. The ticket price range depends on the travel mode: a bus costs an average of $137, and a train costs an average of $291.
Distance: 1429 miles (2301 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$278 Average price Cheapest | $498 Average price | $533 Average price |
50h 20m Average total duration 49h 50m Onboard + 30m Additional time* | 7h 48m Average total duration Fastest 4h 48m Onboard + 3h 0m Additional time* | 43h 27m Average total duration 42h 57m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Buffalo, NY to San Antonio, TX bus times
The table below shows live departures for Buffalo, NY to San Antonio, TX buses for today, Monday, March 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:55 PM Buffalo, NY | 40h55 | 5:50 AM San Antonio, TX | 0 transfersDirect | |
| Tuesday, March 3 | |||||
![]() | 1:45 AM Buffalo, NY | 73h25 | 3:10 AM San Antonio, TX | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Buffalo, NY to San Antonio, TX by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 03
Mar 04
Mar 05
Mar 06
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Mar 08
Mar 09
Why should you book Buffalo, NY to San Antonio, TX buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Buffalo, NY to San Antonio, TX.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Buffalo, NY to San Antonio, TX.
Journey information
Overview: Bus from Buffalo, NY to San Antonio, TX
Buses from Buffalo, NY to San Antonio, TX run on average 9 times per day, taking around 49h 50m. Cheap bus tickets for this journey start at $137 (€109) if you book in advance.
The earliest bus runs at 01:05, the last at 23:20. The fastest bus covers the 1429 miles (2301 km) distance in 40h 55m.
Distance 1429 miles (2301 km) |
Average bus duration 49h 50m |
Cheapest ticket price $137 (€109) |
Buses per day 9 |
Fastest bus 40h 55m |
First bus 01:05 |
Last bus 23:20 |
Bus providers: Greyhound from Buffalo, NY to San Antonio, TXYou can travel by bus between Buffalo, NY to San Antonio, TX with Greyhound for as low as $137 (€109). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Buffalo, NY to San Antonio, TX
Find answers to the most common questions about traveling from Buffalo, NY to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- The Alamo, a historic Spanish mission and site of the famous 1836 battle for Texan independence
- River Walk, a scenic network of walkways along the San Antonio River lined with shops and restaurants
- San Antonio Missions National Historical Park, a UNESCO World Heritage site preserving four Spanish frontier missions
- San Antonio Museum of Art, housing an extensive collection of art from around the world
- Tower of the Americas, offering panoramic views of the city from its observation deck and revolving restaurant.
- Explore the vibrant Pearl District, known for its trendy shops, restaurants, and farmers market
- take a boat tour along the San Antonio River for a unique perspective of the city
- visit the historic Market Square, a lively Mexican market with shops, food, and entertainment
- enjoy a day at Six Flags Fiesta Texas, an amusement park with thrilling rides and shows
- experience the San Antonio Zoo, home to a wide variety of animals and interactive exhibits.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Buffalo, NY to San Antonio, TX
Most popular bus connections from Buffalo, NY
More options for your journey from Buffalo, NY to San Antonio, TX
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