- Must visit
The Alamo Exhibit at the Ralston Family Collections Center
Modern museum displaying artifacts and interpretation related to the Battle of the Alamo and Texas history, complementing the historic mission site.
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Travel Information
Compare train, bus, and flight for Buffalo, NY to San Antonio, TX
Omio recommends booking the flight as it is the most popular option from Buffalo, NY to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from $245. For those with little time consider booking a flight which can get you there in 4h 48m. The ticket price range depends on the travel mode: a bus costs an average of $245, and a train costs an average of $288.
Distance: 1429 miles (2301 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$310 Average price Cheapest | $597 Average price | $796 Average price | $334 Average price (fuel + tolls) |
50h 47m Average total duration 50h 17m Onboard + 30m Additional time* | 7h 48m Average total duration Fastest 4h 48m Onboard + 3h 0m Additional time* | 43h 27m Average total duration 42h 57m Onboard + 30m Additional time* | 24h 10m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Buffalo, NY to San Antonio, TX is a bus with an average price of $310 (€250).
This is compared to other travel options from Buffalo, NY to San Antonio, TX:
A bus is $287 (€231) less than a flight for this route with tickets for a flight from Buffalo, NY to San Antonio, TX costing on average $597 (€480).
A bus is $486 (€391) less than a train for this route with tickets for a train from Buffalo, NY to San Antonio, TX costing on average $796 (€641).
The fastest way to travel from Buffalo, NY to San Antonio, TX is by flight with an average journey time of 4h 48m.
Other travel options to San Antonio, TX take longer:
Train takes on average 42h 57m.
Bus takes on average 50h 17m.
It's helpful to compare your options as there are 3 ways to travel between Buffalo, NY and San Antonio, TX including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Buffalo, NY to San Antonio, TX among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Buffalo, NY to San Antonio, TX Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 11:25PM | Duration 72h05 | Departure days Sun | Cheapest price $161 |
Operator Greyhound | Departure Time 12:20AM | Arrival Time 05:25AM | Duration 54h05 | Departure days Sun | Cheapest price $162 |
Operator Greyhound | Departure Time 12:55AM | Arrival Time 11:25PM | Duration 71h30 | Departure days Sun | Cheapest price $206 |
Operator Greyhound | Departure Time 01:45AM | Arrival Time 03:10AM | Duration 73h25 | Departure days Wed | Cheapest price $264 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 10:00AM | Duration 55h00 | Departure days Sat | Cheapest price $245 |
Operator Greyhound USA | Departure Time 07:55AM | Arrival Time 12:53PM | Duration 52h58 | Departure days Thu, Sun | Cheapest price $160 |
Operator FlixBus | Departure Time 10:50AM | Arrival Time 03:20PM | Duration 53h30 | Departure days Sun | Cheapest price $160 |
Operator Greyhound | Departure Time 11:55AM | Arrival Time 04:55AM | Duration 41h00 | Departure days Wed, Sat | Cheapest price $260 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 05:55AM | Duration 41h00 | Departure days Sat | Cheapest price $391 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 05:35PM | Duration 52h25 | Departure days Sun | Cheapest price $168 |
Operator Greyhound | Departure Time 11:05PM | Arrival Time 12:55PM | Duration 38h50 | Departure days Sun | Cheapest price $158 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 09:10PM | Duration 70h50 | Departure days Sun | Cheapest price $158 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 09:10PM | Duration 70h11 | Departure days Sun | Cheapest price $161 |
Live departures
Buffalo, NY to San Antonio, TX bus times
The table below shows live departures for Buffalo, NY to San Antonio, TX buses for today, Sunday, May 31. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 · · · | 7:55 AM Buffalo, NFTA Metro Center | 41h00 | 11:55 PM San Antonio, N St Mary's St (Greyhound), TX | 4 transfers | |
 FlixBus · FlixBus+ · | 10:50 AM Cheektowaga, BNIA Drway & BNIA Terminal | 53h30 | 3:20 PM San Antonio, N St Mary's St (Greyhound), TX | 3 transfers | |
| FlixBus · FlixBus+ · | 2:10 PM Cheektowaga, BNIA Drway & BNIA Terminal | 52h25 | 5:35 PM San Antonio, N St Mary's St (Greyhound), TX | 4 transfers | |
· · + | 11:05 PM Buffalo, NFTA Metro Center | 38h50 | 12:55 PM San Antonio, N St Mary's St (Greyhound), TX | 3 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 11:20 PM Cheektowaga, BNIA Drway & BNIA Terminal | 70h50 | 9:10 PM San Antonio, Avenue A / Pearl Pkwy, TX | 5 transfers | |
| FlixBus · FlixBus+ · | 11:20 PM Cheektowaga, BNIA Drway & BNIA Terminal | 54h40 | 5:00 AM San Antonio, N St Mary's St (Greyhound), TX | 3 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 11:59 PM Buffalo, NFTA Metro Center | 70h11 | 9:10 PM San Antonio, Avenue A / Pearl Pkwy, TX | 5 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Buffalo, NY to San Antonio, TX by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Buffalo, NY to San Antonio, TX buses with Omio?
Greyhound operates all buses services from Buffalo, NY to San Antonio, TX.
Omio is an official ticket reseller for all your travel options from Buffalo, NY to San Antonio, TX.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Buffalo, NY to San Antonio, TX.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Buffalo, NY to San Antonio, TX.
Journey information
Overview: Bus from Buffalo, NY to San Antonio, TX
USAUSA
Buses from Buffalo, NY to San Antonio, TX run on average 8 times per day, taking around 50h 17m. Cheap bus tickets for this journey start at $245 (€197) if you book in advance.
The earliest bus runs at 00:55, the last at 23:20. The fastest bus covers the 1429 miles (2301 km) distance in 41h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1429 miles (2301 km) |
Average bus duration 50h 17m |
Cheapest ticket price $245 (€197) |
Buses per day 8 |
Fastest bus 41h 0m |
First bus 12:55 AM |
Last bus 11:20 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Buffalo, NY to San Antonio, TXYou can travel by bus between Buffalo, NY to San Antonio, TX with Greyhound for as low as $245 (€197). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
41h 0m
Cheapest Price
$260 (€210)
Greyhound frequency
6 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to San Antonio
Things to do in San Antonio
Discover the best of San Antonio — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio trip today.
- Must visit
San Antonio Museum of Art
Major art museum with strong collections of ancient Mediterranean, Asian, Latin American, and contemporary art in a restored brewery complex.
- Recommended
McNay Art Museum
Renowned museum in a Spanish Colonial Revival mansion, known for modern and contemporary art, sculpture, and beautiful grounds.
- Must visit
San Antonio River Walk
The city’s signature pedestrian area lined with bridges, landscaping, public art, and river-level walkways through downtown.
- Recommended
Historic Market Square
Large Mexican market district with plazas, shops, and cultural atmosphere, one of the most recognizable public areas in the city.
- Recommended
La Villita Historic Arts Village
Historic riverside district of galleries, courtyards, and preserved buildings, popular for strolling and photos near downtown.
- Gluten-free
Puffy Tacos
San Antonio’s signature taco: a fried masa shell that puffs up, then is filled with meats, lettuce, cheese, and salsa. It is a local Tex-Mex classic strongly associated with the city.
- Gluten-free
Barbacoa
Slow-cooked beef, traditionally eaten on weekends and often served in tacos with salsa. It is deeply rooted in South Texas and San Antonio breakfast culture.
Breakfast Tacos
A daily staple in San Antonio, usually built on flour or corn tortillas with fillings like egg, potato, bean, bacon, or chorizo. They reflect the city’s strong Tex-Mex identity.
Bliss
Acclaimed contemporary American restaurant with fine-dining service and seasonal menus. A strong option for a higher-end meal in San Antonio with a consistently strong reputation.
2M Smokehouse
Widely praised barbecue destination known for brisket, house-made sausages, and Texan smokehouse flavors with Mexican influences. Casual, popular, and highly regarded.
La Fonda On Main
Long-running upscale Tex-Mex restaurant with a refined setting and strong local reputation. Known for polished regional dishes, margaritas, and patio dining.
United States Dollar
Generally moderate for U.S. city travel. Tex-Mex, parking, and attractions are fairly priced; hotels rise during major events.
Average meal costs
- Budget
- USD 10-15 for tacos, fast food, or food trucks.
- Mid-range
- USD 20-35 per person at a casual sit-down restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% in restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5 where helpful.
FAQs: Bus from Buffalo, NY to San Antonio, TX
Find answers to the most common questions about traveling from Buffalo, NY to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Buffalo, NY to San Antonio, TX can start from as little as $245 (€197) when you book in advance. The average bus ticket price for Buffalo, NY to San Antonio, TX is $310 (€250) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Buffalo, NY to San Antonio, TX is 41h 0m to travel the 1429 miles (2301 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Buffalo, NY to San Antonio, TX leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Buffalo, NY to San Antonio, TX leaves at 11:20 PM.
There are 8 buses a day from Buffalo, NY to San Antonio, TX which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Buffalo, NY to San Antonio, TX, you can count on Greyhound for the best way to get you to San Antonio, TX. You can also check all possible bus companies who offer a service between Buffalo, NY and San Antonio, TX and compare the amenities they offer before buying a bus ticket.
A trip to San Antonio, TX from Buffalo, NY is worth doing but not as a day trip with a journey time of 41h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Buffalo, NY to San Antonio, TX is September.
It's helpful to compare your options as there are 3 ways to travel between Buffalo, NY and San Antonio, TX including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Buffalo, NY to San Antonio, TX:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Buffalo, NY to San Antonio, TX for bus company Greyhound.
Some of the most interesting sights to explore in San Antonio, TX are:
- The Alamo, a historic Spanish mission and site of the famous 1836 battle for Texan independence
- River Walk, a scenic network of walkways along the San Antonio River lined with shops and restaurants
- San Antonio Missions National Historical Park, a UNESCO World Heritage site preserving four Spanish frontier missions
- San Antonio Museum of Art, housing an extensive collection of art from around the world
- Tower of the Americas, offering panoramic views of the city from its observation deck and revolving restaurant.
The best things to do in San Antonio, TX include:
- Explore the vibrant Pearl District, known for its trendy shops, restaurants, and farmers market
- take a boat tour along the San Antonio River for a unique perspective of the city
- visit the historic Market Square, a lively Mexican market with shops, food, and entertainment
- enjoy a day at Six Flags Fiesta Texas, an amusement park with thrilling rides and shows
- experience the San Antonio Zoo, home to a wide variety of animals and interactive exhibits.
Whether you can cancel your bus ticket from Buffalo, NY to San Antonio, TX depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Buffalo, NY to San Antonio, TX.
Yes, the following luggage options are included when booking a bus ticket from Buffalo, NY to San Antonio, TX:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Buffalo, NY to San Antonio, TX:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Buffalo, NY to San Antonio, TX.
You can reserve your seat on the bus from Buffalo, NY to San Antonio, TX with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Buffalo, NY to San Antonio, TX with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Buffalo, NY to San Antonio, TX with the following bus company: Greyhound.
Since neither Buffalo, NY nor San Antonio, TX are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Buffalo, NY to San Antonio, TX among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Antonio, TX, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the River Walk and Alamo Plaza. Common scams include overcharging by unofficial taxi services and street vendors. It's advisable to use authorized transportation options and stay alert when approached by strangers offering unsolicited help or tours. Staying in well-lit, busy areas and securing personal belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Buffalo, NY to San Antonio, TX
Buffalo
San Antonio
The major bus station for departures in Buffalo is Cheektowaga, BNIA Drway & BNIA Terminal. Find all the information you need to know about services, amenities and connections at Cheektowaga, BNIA Drway & BNIA Terminal for your trip from Buffalo to San Antonio.
Cheektowaga, BNIA Drway & BNIA Terminal
information
Buffalo, NFTA Metro Center
information
The major bus station for arrivals in San Antonio is San Antonio, N St Mary's St (Greyhound). Find all the information you need to know about services, amenities and connections at San Antonio, N St Mary's St (Greyhound) for your trip to San Antonio from Buffalo.
San Antonio, N St Mary's St (Greyhound)
information
San Antonio, Avenue A / Pearl Pkwy
information
Most popular bus connections from Buffalo, NY
More options for your journey from Buffalo, NY to San Antonio, TX
Here are some other resources that might have the information you need
Most popular buses to and from San Antonio, TX and Buffalo, NY
Most popular bus connections to San Antonio, TX
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