- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
Omio recommends booking the flight as it is the most popular option from Buffalo, NY to San Antonio, TX among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €217 For those with little time, consider booking a flight, which has an average total journey time of 7h 56m. Average ticket prices depend on the travel mode: a bus costs an average of €217, while a flight costs an average of €535.
Distance: 1429 miles (2301 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
€217 Average price Cheapest | €535 Average price | €240 Average price | €273 Average price (fuel + tolls) |
47h 41m Average total duration 47h 11m Onboard + 30m Additional time* | 7h 56m Average total duration Fastest 5h 56m Onboard + 2h 0m Additional time* | 43h 39m Average total duration 43h 9m Onboard + 30m Additional time* | 24h 10m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Buffalo, NY to San Antonio, TX:
A bus is €24 less than a train for this route with tickets for a train from Buffalo, NY to San Antonio, TX costing on average €240.
A bus is €319 less than a flight for this route with tickets for a flight from Buffalo, NY to San Antonio, TX costing on average €535.
Other travel options to San Antonio, TX take longer:
Train takes on average 43h 9m.
Bus takes on average 47h 11m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:45AM | Arrival Time 03:10AM | Duration 73h25 | Departure days Wed | Cheapest price €212 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 10:00AM | Duration 55h00 | Departure days Sat | Cheapest price €197 |
Operator Greyhound USA | Departure Time 07:55AM | Arrival Time 12:53PM | Duration 52h58 | Departure days Thu | Cheapest price €394 |
Operator Greyhound | Departure Time 11:55AM | Arrival Time 04:55AM | Duration 41h00 | Departure days Wed, Sat | Cheapest price €210 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 05:55AM | Duration 41h00 | Departure days Sat | Cheapest price €315 |
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Buffalo, NY to San Antonio, TX run on average 8 times per day, taking around 47h 11m. Cheap bus tickets for this journey start at €202 if you book in advance.
The earliest bus runs at 00:55, the last at 23:20. The fastest bus covers the 1429 miles (2301 km) distance in 36h 30m.
Distance 1429 miles (2301 km) |
Average bus duration 47h 11m |
Cheapest ticket price €202 |
Buses per day 8 |
Fastest bus 36h 30m |
First bus 12:55 AM |
Last bus 11:20 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
Official public transport app
UTSA East Campus Lot 1 -> Downtown San Antonio
Find answers to the most common questions about traveling from Buffalo, NY to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most Buffalo, NY to San Antonio, TX buses use the Cheektowaga, BNIA Drway & BNIA Terminal to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare Buffalo, NY and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Ticket office support is available at Buffalo, NFTA Metro Center.
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Here are some other resources that might have the information you need