- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
Cheapest price
$480
Average price
$480
Fastest journey
2 d 4 h 58 m
Average duration
2 d 4 h 58 m
Buses per day
1
Distance
2301 km
The best way to find a cheap bus ticket from Buffalo, NY to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to San Antonio, TX will cost around $480 if you buy it on the day, but the cheapest tickets can be found for only $480.
It's difficult to get from Buffalo, NY to San Antonio, TX without transferring at least 7 times.


Omio recommends booking the flight as it is the most popular option from Buffalo, NY to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from $240. For those with little time consider booking a flight which can get you there in 4h 48m. The ticket price range depends on the travel mode: a bus costs an average of $240, and a train costs an average of $282.
Distance: 1429 miles (2301 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$304 Average price Cheapest | $585 Average price | $780 Average price | $328 Average price (fuel + tolls) |
50h 47m Average total duration 50h 17m Onboard + 30m Additional time* | 7h 48m Average total duration Fastest 4h 48m Onboard + 3h 0m Additional time* | 43h 27m Average total duration 42h 57m Onboard + 30m Additional time* | 24h 10m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Buffalo, NY to San Antonio, TX:
A bus is $281 (€231) less than a flight for this route with tickets for a flight from Buffalo, NY to San Antonio, TX costing on average $585 (€480).
A bus is $476 (€391) less than a train for this route with tickets for a train from Buffalo, NY to San Antonio, TX costing on average $780 (€641).
Other travel options to San Antonio, TX take longer:
Train takes on average 42h 57m.
Bus takes on average 50h 17m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:45AM | Arrival Time 03:10AM | Duration 73h25 | Departure days Wed | Cheapest price $258 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 10:00AM | Duration 55h00 | Departure days Sat | Cheapest price $240 |
Operator Greyhound USA | Departure Time 07:55AM | Arrival Time 12:53PM | Duration 52h58 | Departure days Thu | Cheapest price $480 |
Operator Greyhound | Departure Time 11:55AM | Arrival Time 04:55AM | Duration 41h00 | Departure days Wed, Sat | Cheapest price $255 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 05:55AM | Duration 41h00 | Departure days Sat | Cheapest price $383 |
The table below shows live departures for Buffalo, NY to San Antonio, TX buses for tomorrow, Thursday, July 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:55 AM Buffalo, NY | 52h58 | 12:53 PM San Antonio, TX | 7 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Buffalo, NY to San Antonio, TX run on average 8 times per day, taking around 50h 17m. Cheap bus tickets for this journey start at $240 (€197) if you book in advance.
The earliest bus runs at 00:55, the last at 23:20. The fastest bus covers the 1429 miles (2301 km) distance in 41h 0m.
Distance 1429 miles (2301 km) |
Average bus duration 50h 17m |
Cheapest ticket price $240 (€197) |
Buses per day 8 |
Fastest bus 41h 0m |
First bus 12:55 AM |
Last bus 11:20 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
Official public transport app
UTSA East Campus Lot 1 -> Downtown San Antonio
Find answers to the most common questions about traveling from Buffalo, NY to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most Buffalo, NY to San Antonio, TX buses use the Cheektowaga, BNIA Drway & BNIA Terminal to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare Buffalo, NY and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need