The cheapest and fastest buses from Buffalo, NY to San Antonio, TX
Cheapest price
$755
Average price
$796
Fastest journey
2 d 5 h 23 m
Average duration
2 d 10 h 25 m
Buses per day
2
Distance
2301 km
The best way to find a cheap bus ticket from Buffalo, NY to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to San Antonio, TX will cost around $796 if you buy it on the day, but the cheapest tickets can be found for only $755.
It's difficult to get from Buffalo, NY to San Antonio, TX without transferring at least 7 times.




Travel Information
Compare train and bus for Buffalo, NY to San Antonio, TX
Omio recommends booking the train as it is the most popular option from Buffalo, NY to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from €109. For those with little time consider booking a train which can get you there in 42h 57m. The ticket price range depends on the travel mode: a bus costs an average of €109, and a train costs an average of €191.
Distance: 1429 miles (2301 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€109 Average price Cheapest | €251 Average price |
53h 20m Average total duration 52h 50m Onboard + 30m Additional time* | 43h 27m Average total duration Fastest 42h 57m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Buffalo, NY to San Antonio, TX bus times
The table below shows live departures for Buffalo, NY to San Antonio, TX buses for tomorrow, Friday, January 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:55 AM Buffalo, NY | 53h23 | 1:18 PM San Antonio, TX | 8 transfers | |
![]() | 7:55 AM Buffalo, NY | 63h27 | 11:22 PM San Antonio, TX | 7 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Buffalo, NY to San Antonio, TX by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 16
Jan 17
Jan 18
Jan 19
Jan 20
Jan 21
Jan 22
Journey information
Overview: Bus from Buffalo, NY to San Antonio, TX
Buses from Buffalo, NY to San Antonio, TX run on average 9 times per day, taking around 52h 50m. Cheap bus tickets for this journey start at $135 (€109) if you book in advance.
The earliest bus runs at 01:05, the last at 23:20. The fastest bus covers the 1429 miles (2301 km) distance in 52h 50m.
Distance 1429 miles (2301 km) |
Average bus duration 52h 50m |
Cheapest ticket price $135 (€109) |
Buses per day 9 |
Fastest bus 52h 50m |
First bus 01:05 |
Last bus 23:20 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Buffalo, NY to San Antonio, TX start from as low as $135 (€109) if booked well in advance.
- Standard Fares: Typically, trains cost $135 (€109) depending on the train type and class.
Journey Duration & Frequency
- On average there are 9 daily trains from Buffalo, NY to San Antonio, TX with 0 direct service.
- The fastest trains can take as little as 52h 50m but the average duration is 52h 50m
Train Operators
- Travel from Buffalo, NY to San Antonio, TX with Greyhound
- The most booked train company for this route on Omio is Greyhound.
Stations & Schedule
- Most trains depart from Cheektowaga, BNIA Drway & BNIA Terminal and arrive in San Antonio, N St Mary's St (Greyhound), TX
- First train typically departs at 01:05 AM and the last at 11:20 PM
Bus providers: Greyhound from Buffalo, NY to San Antonio, TXYou can travel by bus between Buffalo, NY to San Antonio, TX with Greyhound for as low as $135 (€109). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Buffalo, NY to San Antonio, TX
Find answers to the most common questions about traveling from Buffalo, NY to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- The Alamo, a historic Spanish mission and site of the famous 1836 battle for Texan independence
- River Walk, a scenic network of walkways along the San Antonio River lined with shops and restaurants
- San Antonio Missions National Historical Park, a UNESCO World Heritage site preserving four Spanish frontier missions
- San Antonio Museum of Art, housing an extensive collection of art from around the world
- Tower of the Americas, offering panoramic views of the city from its observation deck and revolving restaurant.
- Explore the vibrant Pearl District, known for its trendy shops, restaurants, and farmers market
- Take a boat tour along the San Antonio River for a unique perspective of the city
- Visit the historic Market Square, a lively Mexican market with shops, food, and entertainment
- Enjoy a day at Six Flags Fiesta Texas, an amusement park with thrilling rides and shows
- Experience the San Antonio Zoo, home to a wide variety of animals and interactive exhibits.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Buffalo, NY to San Antonio, TX, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Buffalo, NY to San Antonio, TX
More options for your journey from Buffalo, NY to San Antonio, TX
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