Travel Information
Compare train, bus, and flight for Amsterdam to Mainz
Omio recommends booking the train as it is the most popular option from Amsterdam to Mainz among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $57 For those with little time, consider booking a flight, which has an average total journey time of 5h 5m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $57, while a flight costs an average of $585.
Distance: 221 miles (356 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$106 Average price | $57 Average price Cheapest | $585 Average price | $96 Average price (fuel + tolls) |
5h 21m Average total duration 4h 51m Onboard + 30m Additional time* | 10h 12m Average total duration 9h 42m Onboard + 30m Additional time* | 5h 5m Average total duration Fastest 3h 5m Onboard + 2h 0m Additional time* | 4h 42m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions | 1.1 - 2.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Amsterdam to Mainz
Compare the available ways to get from Amsterdam to Mainz, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Amsterdam to Mainz:
A bus is $49 less than a train for this route with tickets for a train from Amsterdam to Mainz costing on average $106.
A bus is $529 less than a flight for this route with tickets for a flight from Amsterdam to Mainz costing on average $585.
Other travel options to Mainz take longer:
Train takes on average 5h 21m.
Bus takes on average 10h 12m.
Tickets start at around $106 compared to roughly $96 in fuel and tolls — a saving of about -$9. The journey takes 4h 51m versus 4h 42m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Amsterdam to Mainz
How to get from Amsterdam to Mainz by train, bus or flight.
Our recommendation
The best way to travel from Amsterdam to Mainz is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague)2:00 PM 8h00 Amsterdam, Piarcoplein (Amsterdam Sloterdijk) 10:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) $28 1 One-way 0 transfers
Cheapest
(Amsterdam -> Prague)2:00 PM 8h00 Amsterdam, Piarcoplein (Amsterdam Sloterdijk) 10:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) $28 1 One-way 0 transfers
Fastest
KL181912:30 PM 1h05 Amsterdam Airport Schiphol 1:35 PM Frankfurt am Main Airport $160 1 One-way 0 transfers
Other options
IC 3545 · 20085 · 10629 · IC 204812:56 PM 5h43 Amsterdam Zuid 6:39 PM Mainz Hbf $47 1 One-way 3 transfers
IC 3945 · 18945 · 26827 · IC 204812:44 PM 5h55 Amsterdam Centraal 6:39 PM Mainz Hbf $47 1 One-way 3 transfers
IC 3529 · 20077 · 10621 · IC 20448:56 AM 5h43 Amsterdam Zuid 2:39 PM Mainz Hbf $52 1 One-way 3 transfers
FlixBus · FlixBus7:00 AM 9h15 Amsterdam, Piarcoplein (Amsterdam Sloterdijk) 4:15 PM Mainz, Binger Schlag (Kurzzeitparkplatz) $40 1 One-way 1 transfer
FlixBus · FlixBus4:00 AM 12h15 Schiphol, Airport Terminal 1 4:15 PM Mainz, Binger Schlag (Kurzzeitparkplatz) $40 1 One-way 1 transfer
FlixBus · FlixBus3:15 AM 13h00 Amsterdam Central Bus Station (Bus Stop H) 4:15 PM Mainz, Binger Schlag (Kurzzeitparkplatz) $41 1 One-way 1 transfer
KL18259:20 PM 1h05 Amsterdam Airport Schiphol 10:25 PM Frankfurt am Main Airport $160 1 One-way 0 transfers
KL181710:00 AM 1h10 Amsterdam Airport Schiphol 11:10 AM Frankfurt am Main Airport $160 1 One-way 0 transfers
KL18158:30 AM 1h10 Amsterdam Airport Schiphol 9:40 AM Frankfurt am Main Airport $160 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Amsterdam to Mainz
Travel to Mainz easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Amsterdam to Mainz.

This is compared to other travel options from Amsterdam to Mainz:
A bus is $49 less than a train for this route with tickets for a train from Amsterdam to Mainz costing on average $106.
A bus is $529 less than a flight for this route with tickets for a flight from Amsterdam to Mainz costing on average $585.
Other travel options to Mainz take longer:
Train takes on average 5h 21m.
Bus takes on average 10h 12m.
- Around 44 flights per day.
- Around 6 trains per day.
- Around 4 buses per day.
However, we recommend checking specific travel dates for your route between Amsterdam and Mainz as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Amsterdam Airport Schiphol and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Amsterdam Centraal and arrive in Mainz Hbf.
- Buses mostly depart from Amsterdam, Piarcoplein (Amsterdam Sloterdijk) and arrive in Mainz, Binger Schlag (Kurzzeitparkplatz).
- Travel with Air France, Lufthansa, British Airways, KLM, Swiss, Qatar Airways, Turkish Airlines, Lot Polish Airlines, KLM Cityhopper, Air Baltic, Austrian Airlines, Lufthansa Cityline, Air Dolomiti, Helvetic Airways, BA Cityflyer, CitizenPlane to go to Mainz by flight.
- Travel with Deutsche Bahn, VIAS Rail GmbH to go to Mainz by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Mainz by bus.
- 9 direct flights per day with Lufthansa, KLM, KLM Cityhopper, Lufthansa Cityline, Air Dolomiti.
Travelling from Amsterdam to Mainz: related information
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