Travel Information
Compare bus, train, and flight for Brussels to Mainz
Omio recommends booking the train as it is the most popular option from Brussels to Mainz among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $47 For those with little time, consider booking a train, which has an average total journey time of 4h 12m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $47, while a flight costs an average of $454.
Distance: 183 miles (295 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$123 Average price | $47 Average price Cheapest | $454 Average price | $72 Average price (fuel + tolls) |
4h 12m Average total duration Fastest 3h 42m Onboard + 30m Additional time* | 8h 56m Average total duration 8h 26m Onboard + 30m Additional time* | 4h 26m Average total duration 2h 26m Onboard + 2h 0m Additional time* | 3h 51m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | 0.9 - 1.8kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Brussels to Mainz
Compare the available ways to get from Brussels to Mainz, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Brussels to Mainz:
A bus is $77 less than a train for this route with tickets for a train from Brussels to Mainz costing on average $123.
A bus is $408 less than a flight for this route with tickets for a flight from Brussels to Mainz costing on average $454.
Other travel options to Mainz take longer:
Flight takes on average 4h 26m.
Bus takes on average 8h 56m.
You'll arrive about 9m sooner (3h 42m by train vs 3h 51m by car). Tickets start at around $123 compared to roughly $72 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Travel optionsfrom Brussels to Mainz
How to get from Brussels to Mainz by train, bus or flight.
Our recommendation
The best way to travel from Brussels to Mainz is by taking a bus because it’s the best combination of price and speed.

9:30 AM 5h25 Brussels 2:55 PM Mainz $31 1 One-way 0 transfers
Cheapest

9:30 AM 5h25 Brussels 2:55 PM Mainz $31 1 One-way 0 transfers
Fastest

9:30 AM 5h25 Brussels 2:55 PM Mainz $31 1 One-way 0 transfers
Other options

7:10 PM 9h40 Brussels 4:50 AM Mainz $39 1 One-way 0 transfers
8:30 AM 5h25 Brussels 1:55 PM Mainz $42 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Brussels to Mainz
Travel to Mainz easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brussels to Mainz.

This is compared to other travel options from Brussels to Mainz:
A bus is $77 less than a train for this route with tickets for a train from Brussels to Mainz costing on average $123.
A bus is $408 less than a flight for this route with tickets for a flight from Brussels to Mainz costing on average $454.
Other travel options to Mainz take longer:
Flight takes on average 4h 26m.
Bus takes on average 8h 56m.
- Around 28 flights per day.
- Around 5 trains per day.
- Around 3 buses per day.
However, we recommend checking specific travel dates for your route between Brussels and Mainz as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Brussels Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Brussels-Midi and arrive in Mainz Hbf.
- Buses mostly depart from Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord) and arrive in Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
- Travel with BlaBlaCar Bus, FlixBus to go to Mainz by bus.
- Travel with Deutsche Bahn, Eurostar, Intercity, Regional to go to Mainz by train.
- Travel with Brussels Airlines, KLM, KLM Cityhopper, British Airways, Lot Polish Airlines, CitizenPlane, Helvetic Airways, Air Baltic, Qatar Airways, Lufthansa, Lufthansa City Airlines, Austrian Airlines, Swiss, Lufthansa Cityline, BA Cityflyer, ITA, Edelweiss Air, Thai Airways to go to Mainz by flight.
- 1 direct buses per day with FlixBus.
- 6 direct flights per day with Brussels Airlines, CitizenPlane, Air Baltic.
Travelling from Brussels to Mainz: related information
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