Travel Information
Compare bus, train, and flight for Brussels to Mainz
Omio recommends booking the flight as it is the most popular option from Brussels to Mainz among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $48 For those with little time, consider booking a train, which has an average total journey time of 4h 15m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $48, while a flight costs an average of $492.
Distance: 183 miles (295 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$492 Average price | $130 Average price | $48 Average price Cheapest | $74 Average price (fuel + tolls) |
4h 42m Average total duration 2h 42m Onboard + 2h 0m Additional time* | 4h 15m Average total duration Fastest 3h 45m Onboard + 30m Additional time* | 8h 12m Average total duration 7h 42m Onboard + 30m Additional time* | 3h 51m Average total duration (door-to-door) |
0.9 - 1.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brussels to Mainz:
A bus is $69 (€56) less than a train for this route with tickets for a train from Brussels to Mainz costing on average $106 (€86).
A bus is $222 (€182) less than a flight for this route with tickets for a flight from Brussels to Mainz costing on average $259 (€212).
Other travel options to Mainz take longer:
Train takes on average 4h 13m.
Bus takes on average 5h 50m.
You'll arrive about 8m sooner (3h 43m by train vs 3h 51m by car). Tickets start at around $106 (€86) compared to roughly $74 (€60) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Travel optionsfrom Brussels to Mainz
How to get from Brussels to Mainz by train, bus or flight.
Our recommendation
The best way to travel from Brussels to Mainz is by taking a bus because it’s the best combination of price and speed.
FlixBus10:25 AM5h50Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord)4:15 PMMainz, Binger Schlag (Kurzzeitparkplatz)$381One-way0 transfers
Cheapest
FlixBus10:25 AM5h50Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord)4:15 PMMainz, Binger Schlag (Kurzzeitparkplatz)$381One-way0 transfers
Fastest
SN26177:30 PM1h05Brussels Airport8:35 PMFrankfurt am Main Airport$5541One-way0 transfers
Other options
ICE 15 · IC 204410:25 AM4h14Brussels-Midi2:39 PMMainz Hbf$1491One-way1 transfer
ICE 15 · S810:25 AM3h30Brussels-Midi1:55 PMMainz Hbf$1971One-way1 transfer
4744 · 5415211:35 PM12h50Brussels, Brussels South (Gare du Midi)12:25 PMDarmstadt, Hauptbahnhof Fernbusse$531One-way1 transfer
4744 · 5415211:35 PM13h20Brussels, Brussels South (Gare du Midi)12:55 PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$531One-way1 transfer
50324 · 3048211:30 AM12h05Brussels, Brussels South (Gare du Midi)11:35 PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$661One-way1 transfer
KL1700 · KL18176:20 AM4h45Brussels Airport11:05 AMFrankfurt am Main Airport$3971One-way1 transfer
KL1700 · KL18196:20 AM7h15Brussels Airport1:35 PMFrankfurt am Main Airport$3971One-way1 transfer
KL1704 · KL181910:25 AM3h10Brussels Airport1:35 PMFrankfurt am Main Airport$4171One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Brussels to Mainz
Travel to Mainz easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brussels to Mainz.

This is compared to other travel options from Brussels to Mainz:
A bus is $82 (€67) less than a train for this route with tickets for a train from Brussels to Mainz costing on average $130 (€106).
A bus is $444 (€363) less than a flight for this route with tickets for a flight from Brussels to Mainz costing on average $492 (€402).
Other travel options to Mainz take longer:
Flight takes on average 4h 42m.
Bus takes on average 8h 12m.
- Around 27 flights per day.
- Around 5 trains per day.
- Around 3 buses per day.
However, we recommend checking specific travel dates for your route between Brussels and Mainz as scheduled services by bus, train, and flight can vary by season or day of the week.
- Trains mostly depart from Brussels-Midi and arrive in Mainz Hbf.
- Buses mostly depart from Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord) and arrive in Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
- Flights mostly depart from Brussels Airport and arrive in Frankfurt am Main Airport.
- Travel with FlixBus, BlaBlaCar, BlaBlaCar Bus to go to Mainz by bus.
- Travel with Deutsche Bahn, Deutsche Bahn Intercity (DB IC) to go to Mainz by train.
- Travel with Lufthansa, Brussels Airlines to go to Mainz by flight.
- 1 direct buses per day with FlixBus, BlaBlaCar.
- 5 direct flights per day with Lufthansa, Brussels Airlines.
Travelling from Brussels to Mainz: related information
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