Travel Information
Compare bus, train, and flight for Milan to Brindisi
Omio recommends booking the flight as it is the most popular option from Milan to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from $20. For those with little time consider booking a flight which can get you there in 1h 43m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of $20, and a flight costs an average of $21.
Distance: 553 miles (890 km)
Compare flight with
Most popular Flight | Train | Bus |
|---|---|---|
$132 Average price | $90 Average price | $48 Average price Cheapest |
4h 43m Average total duration Fastest 1h 43m Onboard + 3h 0m Additional time* | 11h 29m Average total duration 10h 59m Onboard + 30m Additional time* | 13h 27m Average total duration 12h 57m Onboard + 30m Additional time* |
- CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | 0.9 - 2.2kg CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Milan to Brindisi
How to get from Milan to Brindisi by train, bus or flight.
Our recommendation
The best way to travel from Milan to Brindisi is by taking a bus because it’s the best combination of price and speed.
043Cheapest
043Fastest
AZ1629Other options
InterCityNotte 35545
InterCityNotte 35567
Intercity 607
043
FlixBus
FlixBus
U23515
U23517
FR 3416Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Milan to Brindisi
Travel to Brindisi easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Brindisi.

This is compared to other travel options from Milan to Brindisi:
A bus is $1 (€1) less than a flight for this route with tickets for a flight from Milan to Brindisi costing on average $21 (€17).
A bus is $30 (€24) less than a train for this route with tickets for a train from Milan to Brindisi costing on average $49 (€40).
Other travel options to Brindisi take longer:
Train takes on average 7h 54m.
Bus takes on average 12h 40m.
- Around 36 flights per day.
- Around 25 buses per day.
- Around 19 trains per day.
However, we recommend checking specific travel dates for your route between Milan and Brindisi as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Milan Linate Airport and arrive in Brindisi Airport.
- Trains mostly depart from Milan Centrale and arrive in Brindisi station.
- Buses mostly depart from Milano, Autostazione Lampugnano and arrive in Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale).
- Travel with KM Malta Airlines, Ryanair, easyJet, ITA, Neos Air to go to Brindisi by flight.
- Travel with Marino Autolinee, Itabus, FlixBus, BlaBlaCar to go to Brindisi by bus.
- Travel with Intercity Notte, Frecciarossa, Intercity, Italo to go to Brindisi by train.
- 8 direct flights per day with KM Malta Airlines, Ryanair, easyJet, ITA, Neos Air.
- 6 direct buses per day with Marino Autolinee, FlixBus, BlaBlaCar.
- 9 direct trains per day with Intercity Notte, Frecciarossa, Intercity.
Travelling from Milan to Brindisi: related information
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