Travel Information
Compare train, bus, and flight for Düsseldorf to Lyon
Omio recommends booking the bus as it is the most popular option from Düsseldorf to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $39. For those with little time consider booking a flight which can get you there in 2h 20m. The ticket price range depends on the travel mode: a bus costs an average of $39, and a flight costs an average of $92.
Distance: 388 miles (625 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$68 Average price Cheapest | $239 Average price | $255 Average price |
12h 43m Average total duration 12h 13m Onboard + 30m Additional time* | 6h 57m Average total duration 6h 27m Onboard + 30m Additional time* | 5h 20m Average total duration Fastest 2h 20m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Düsseldorf to Lyon
How to get from Düsseldorf to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Düsseldorf to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus11:00 PM10h45Düsseldorf, ZOB am Hbf9:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1011One-way0 transfers
Cheapest
50429 · 5061710:40 AM16h50Düsseldorf, ZOB am Hbf3:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$881One-way1 transfer
Fastest
AF7364+
AF11076:55 AM3h35Dusseldorf Airport10:30 AMLyon Saint Exupery Airport$3261One-way1 transfer
Other options
ICE 107+
TGV 958012:27 PM7h31Düsseldorf Hbf7:58 PMLyon Part Dieu$2501One-way1 transfer
9414+
98266:09 AM7h51Düsseldorf Hbf2:00 PMLyon Part Dieu$4011One-way1 transfer
FlixBus · FlixBus1:45 PM15h00Düsseldorf, ZOB am Hbf4:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$971One-way1 transfer
50457 · 501078:15 AM16h05Düsseldorf, ZOB am Hbf12:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1101One-way1 transfer
50449 · 947659:45 PM16h55Düsseldorf, ZOB am Hbf2:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1181One-way1 transfer
VY1899 · VY12209:00 PM12h05Dusseldorf Airport9:05 AMLyon Saint Exupery Airport$3041One-way1 transfer
VY1897 · VY12249:45 AM6h00Dusseldorf Airport3:45 PMLyon Saint Exupery Airport$4391One-way1 transfer
KL1796+
KL14316:20 AM7h05Dusseldorf Airport1:25 PMLyon Saint Exupery Airport$4311One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Düsseldorf to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Düsseldorf to Lyon.

This is compared to other travel options from Düsseldorf to Lyon:
A bus is $16 (€12) less than a train for this route with tickets for a train from Düsseldorf to Lyon costing on average $54 (€43).
A bus is $53 (€43) less than a flight for this route with tickets for a flight from Düsseldorf to Lyon costing on average $92 (€74).
Other travel options to Lyon take longer:
Train takes on average 6h 46m.
Bus takes on average 10h 45m.
- Around 14 flights per day.
- Around 6 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Düsseldorf and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Dusseldorf Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Düsseldorf Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Düsseldorf, ZOB am Hbf and arrive in Lyon, Perrache Bus Station.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Lyon by bus.
- Travel with TGV, SNCF | TGV INOUI, Deutsche Bahn to go to Lyon by train.
- Travel with Eurowings, Lufthansa, Lufthansa Cityline, Air Dolomiti, Air Baltic, KLM, Vueling, Air France to go to Lyon by flight.
- 1 direct buses per day with FlixBus, BlaBlaCar.
Travelling from Düsseldorf to Lyon: related information
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