Travel Information
Compare train, bus, and flight for Lyon to Düsseldorf
Omio recommends booking the train as it is the most popular option from Lyon to Düsseldorf among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $77 For those with little time, consider booking a flight, which has an average total journey time of 4h 21m. Average ticket prices depend on the travel mode: a bus costs an average of $77, while a flight costs an average of $232.
Distance: 388 miles (625 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$192 Average price | $77 Average price Cheapest | $232 Average price |
6h 50m Average total duration 6h 20m Onboard + 30m Additional time* | 12h 21m Average total duration 11h 51m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 2h 21m Onboard + 2h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Lyon to Düsseldorf
How to get from Lyon to Düsseldorf by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Düsseldorf is by taking a bus because it’s the best combination of price and speed.
51470 · 504483:30 PM16h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)7:45 AMDüsseldorf, ZOB am Hbf$481One-way1 transfer
Cheapest
51470 · 504483:30 PM16h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)7:45 AMDüsseldorf, ZOB am Hbf$481One-way1 transfer
Fastest
LH1077+
LH42162:35 PM3h25Lyon Saint Exupery Airport6:00 PMDusseldorf Airport$3221One-way1 transfer
Other options
TGV 9583+
ICE 10610:01 AM7h31Lyon Part Dieu5:32 PMDüsseldorf Hbf$1611One-way1 transfer
6616+
945912:00 PM7h40Lyon Part Dieu7:40 PMDüsseldorf Hbf$1881One-way1 transfer
6616+
947112:00 PM9h42Lyon Part Dieu9:42 PMDüsseldorf Hbf$1881One-way1 transfer
50618 · 504281:20 AM17h35Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)6:55 PMDüsseldorf, ZOB am Hbf$641One-way1 transfer
FlixBus · FlixBus5:20 AM15h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)8:40 PMDüsseldorf, ZOB am Hbf$681One-way1 transfer
FlixBus · FlixBus3:15 PM13h40Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)4:55 AMDüsseldorf, ZOB am Hbf$691One-way1 transfer
VY1221 · VY189611:35 PM9h45Lyon Saint Exupery Airport9:20 AMDusseldorf Airport$1351One-way1 transfer
KL1428 · KL18019:55 AM4h00Lyon Saint Exupery Airport1:55 PMDusseldorf Airport$2261One-way1 transfer
KL1434 · KL17976:20 PM13h20Lyon Saint Exupery Airport7:40 AMDusseldorf Airport$2261One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 05
Sep 06
Sep 07
Sep 08
Sep 09
Sep 10
Sep 11
Sep 12
Sep 13
Sep 14
Sep 15
Sep 16
Sep 17
Sep 18
Sep 19
Sep 20
Sep 21
Sep 22
Sep 23
Sep 24
Sep 25
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Lyon to Düsseldorf
Travel to Düsseldorf easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Düsseldorf.

This is compared to other travel options from Lyon to Düsseldorf:
A bus is $116 less than a train for this route with tickets for a train from Lyon to Düsseldorf costing on average $192.
A bus is $155 less than a flight for this route with tickets for a flight from Lyon to Düsseldorf costing on average $232.
Other travel options to Düsseldorf take longer:
Train takes on average 6h 50m.
Bus takes on average 12h 21m.
- Around 18 flights per day.
- Around 7 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Düsseldorf as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Dusseldorf Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Düsseldorf Hbf.
- Buses mostly depart from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) and arrive in Düsseldorf, ZOB am Hbf.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar, Alsa to go to Düsseldorf by bus.
- Travel with TGV, Eurostar, SNCF | TGV INOUI to go to Düsseldorf by train.
- Travel with Eurowings, Lufthansa Cityline, Lufthansa, Air Baltic, Air Dolomiti, KLM, Austrian Airlines, Vueling, Helvetic Airways, Avion Express Malta to go to Düsseldorf by flight.
- 1 direct buses per day with FlixBus, BlaBlaCar.
- 1 direct flights per day with Avion Express Malta.
Travelling from Lyon to Düsseldorf: related information
Here are some other resources that might have the information you need

