- Must visit
National Museum
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
Cheapest price
$48
Average price
$88
Fastest journey
8 h 43 m
Average duration
9 h 21 m
Trains per day
3
Distance
528 km
The best way to find a cheap train ticket from Wuppertal to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Wuppertal to Prague will cost around $88 if you buy it on the day, but the cheapest tickets can be found for only $48.
Of the 3 trains that leave Wuppertal for Prague on Tue, Jun 16, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jun 16 the direct trains cover the 528 km distance in an average of 9 h 21 m but if you time it right, some trains will get you there in just 8 h 43 m .
On Tue, Jun 16 the slowest trains will take 10 h 18 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the train as it is the most popular option from Wuppertal to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $37. For those with little time consider booking a flight which can get you there in 1h 17m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $37, and a flight costs an average of $78.
Distance: 328 miles (528 km)
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$108 Average price | $203 Average price | $60 Average price Cheapest | $126 Average price (fuel + tolls) |
9h 23m Average total duration 8h 53m Onboard + 30m Additional time* | 4h 17m Average total duration Fastest 1h 17m Onboard + 3h 0m Additional time* | 10h 4m Average total duration 9h 34m Onboard + 30m Additional time* | 7h 17m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.2kg CO2 emissions | 0.5 - 1.3kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Wuppertal to Prague:
A bus is $47 (€38) less than a train for this route with tickets for a train from Wuppertal to Prague costing on average $108 (€87).
A bus is $143 (€116) less than a flight for this route with tickets for a flight from Wuppertal to Prague costing on average $203 (€164).
Other travel options to Prague take longer:
Train takes on average 8h 53m.
Bus takes on average 9h 34m.
Tickets start at around $108 (€87) compared to roughly $126 (€102) in fuel and tolls — a saving of about $19 (€15). The journey takes 8h 53m versus 7h 17m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Wuppertal to Prague trains for today, Monday, June 15. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
S8 · ICE 621 · 3569+ 359 | 8:38 AM Wuppertal Hbf | 9h43 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ERB 20069 · ICE 545 · rj 383 · rj 10177 | On time 8:42 AM Wuppertal Hbf | 10h33 | 7:15 PM Prague-Holešovice | 4 transfers | |
ERB 20077 · ICE 549 · rj 385 | On time 12:42 PM Wuppertal Hbf | 8h43 | 9:25 PM Prague hlavní nádraží | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Wuppertal to Prague run on average 9 times per day, taking around 8h 53m. Cheap train tickets for this journey start at $48 (€39) but you can travel from only $37 (€30) by bus.
The earliest train runs at 00:23, the last at 23:58. The fastest train covers the 328 miles (528 km) distance in 8h 43m.
Distance 328 miles (528 km) |
Average train duration 8h 53m |
Cheapest ticket price $48 (€39) |
Trains per day 9 |
Fastest train 8h 43m |
First train 12:23 AM |
Last train 11:58 PM |
Cheapest Month Dec |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Fri |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
A significant museum complex preserving Jewish history and heritage through synagogues, ceremonial objects, and exhibitions in Josefov.
A highly regarded design museum with glass, ceramics, fashion, graphics, and decorative arts in a historic building near the Old Town.
Prague’s ceremonial heart, surrounded by historic facades, churches, and major landmarks; essential for first-time visitors.
A picturesque historic district below Prague Castle with baroque streets, embassies, gardens, and a romantic atmosphere.
A major boulevard-like square central to modern Czech history, shopping, and public life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the best-known classic Czech festive dishes.
Roast pork served with dumplings and braised cabbage. This is a cornerstone of traditional Czech home-style cooking and pub menus.
Czech-style goulash is usually a rich beef stew with onions, paprika, and bread dumplings. It is a hearty staple often eaten in historic Prague pubs.
Established traditional restaurant known for duck, old-Bohemian recipes, and elegant historic interiors. A strong choice for a refined Czech meal.
Well-known Old Town restaurant offering polished Czech classics and seasonal dishes in a stylish but approachable atmosphere.
A famous modern Czech beer hall serving classic dishes, fresh Pilsner, and dependable traditional cooking in a lively central setting.
Moderate by European standards. Beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip needed for counter service, though small change is appreciated.
Official public transport app
Prague hlavní nádraží -> Old Town Square, Prague
Find answers to the most common questions about traveling from Wuppertal to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need