- Must visit
Museum aan de Stroom (MAS)
Antwerp’s flagship museum on the river, covering the city’s history, trade, migration and global connections. The rooftop panorama is especially popular.
Cheapest price
$324
Average price
$455
Fastest journey
11 h 45 m
Average duration
11 h 57 m
Trains per day
8
Distance
717 km
The best way to find a cheap train ticket from Prague to Antwerp is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Antwerp will cost around $455 if you buy it on the day, but the cheapest tickets can be found for only $324.
It's difficult to get from Prague to Antwerp without transferring at least 4 times.
RJ 382 · ICE 546 · ICE 224 · IC 3671
RJ 384 · ICE 640 · ICE 124 · IC 3655
RJ 178 · ICE 548 · 10146 · 20084
RJ 382 · ICE 546 · 10154 · 20088
RJ 384 · ICE 640 · 10138 · 20080
RJ 178 · ICE 548 · 10146 · 20084
RJ 382 · ICE 546 · 10154 · 20088
RJ 394 · ICE 640 · 10138 · 20080
RJ 384 · ICE 640 · 10138 · 20080
RJ 382 · ICE 546 · ICE 224 · IC 3671Omio recommends booking the bus as it is the most popular option from Prague to Antwerp among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a flight which can get you there in 1h 26m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $53, and a train costs an average of $80.
Distance: 445 miles (717 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$189 Average price | $83 Average price Cheapest | $117 Average price | $178 Average price (fuel + tolls) |
13h 22m Average total duration 12h 52m Onboard + 30m Additional time* | 17h 23m Average total duration 16h 53m Onboard + 30m Additional time* | 4h 26m Average total duration Fastest 1h 26m Onboard + 3h 0m Additional time* | 8h 50m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions Lowest | 0.7 - 1.8kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Antwerp:
A bus is $33 (€27) less than a flight for this route with tickets for a flight from Prague to Antwerp costing on average $117 (€94).
A bus is $105 (€85) less than a train for this route with tickets for a train from Prague to Antwerp costing on average $189 (€152).
Other travel options to Antwerp take longer:
Train takes on average 12h 52m.
Bus takes on average 16h 53m.
Tickets start at around $189 (€152) compared to roughly $178 (€144) in fuel and tolls — a saving of about $-10.46 (€-8.42). The journey takes 12h 52m versus 8h 50m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Prague to Antwerp trains for tomorrow, Sunday, May 31. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
RJ 384 · ICE 640 · ICE 124 · IC 3655 | On time 6:31 AM Prague hlavní nádraží | 12h45 | 7:16 PM Antwerp-Central | 4 transfers | |
RJ 394 · ICE 640 · 10138 · 20080 | On time 6:31 AM Prague hlavní nádraží | 11h45 | 6:16 PM Antwerp-Central | 6 transfers | |
RJ 384 · ICE 640 · 10138 · 20080 | On time 6:31 AM Prague hlavní nádraží | 11h45 | 6:16 PM Antwerp-Central | 6 transfers | |
RJ 394 · ICE 640 · ICE 124 · IC 3655 | On time 6:31 AM Prague hlavní nádraží | 12h45 | 7:16 PM Antwerp-Central | 4 transfers | |
RJ 178 · ICE 548 · 10146 · 20084 | On time 8:31 AM Prague hlavní nádraží | 11h45 | 8:16 PM Antwerp-Central | 6 transfers | |
RJ 382 · ICE 1544 · ICE 10 · IC 3122 | On time 10:31 AM Prague hlavní nádraží | 13h22 | 11:53 PM Antwerp-Central | 3 transfers | |
RJ 382 · ICE 546 · ICE 224 · IC 3671 | On time 10:31 AM Prague hlavní nádraží | 12h45 | 11:16 PM Antwerp-Central | 4 transfers | |
RJ 382 · ICE 546 · 10154 · 20088 | On time 10:31 AM Prague hlavní nádraží | 11h45 | 10:16 PM Antwerp-Central | 6 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Prague to Antwerp run on average 4 times per day, taking around 12h 52m. Cheap train tickets for this journey start at $80 (€65) but you can travel from only $36 (€29) by flight.
The earliest train runs at 03:14, the last at 23:58. The fastest train covers the 445 miles (717 km) distance in 11h 35m.
Distance 445 miles (717 km) |
Average train duration 12h 52m |
Cheapest ticket price $80 (€65) |
Trains per day 4 |
Fastest train 11h 35m |
First train 3:14 AM |
Last train 11:58 PM |
Cheapest Month Nov |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Wed |
Best time to book 21 days |
Discover the best of Antwerp — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Antwerp trip today.
Antwerp’s flagship museum on the river, covering the city’s history, trade, migration and global connections. The rooftop panorama is especially popular.
The restored home and studio of Peter Paul Rubens, offering insight into the life and work of Antwerp’s most famous Baroque painter.
Major fine arts museum with Flemish masters, modern art and a landmark renovation that made it one of Belgium’s top cultural attractions.
Antwerp’s historic main square, framed by guild houses, the city hall and the Brabo Fountain. A classic first stop in the old center.
Revived docklands neighborhood around MAS, packed with waterside views, modern architecture and some of Antwerp’s most shared photo spots.
Antwerp’s grand central shopping boulevard, known for impressive architecture and heavy foot traffic between major city sights.
Mussels steamed with white wine, celery, onion, or cream, traditionally served with Belgian fries. A classic meal in Antwerp and across Flanders.
Flemish beef stew slowly braised in dark Belgian beer, often slightly sweet-sour and served with fries. A beloved comfort dish in Antwerp.
A creamy chicken and mushroom ragout served in a puff pastry case, often with fries. A traditional Belgian brasserie favorite.
Renowned fine-dining restaurant in a former chapel, celebrated for creative contemporary cuisine and an exceptional destination atmosphere.
Historic Antwerp brewery and visitor venue best known for Bolleke De Koninck, with beer-focused dining and a lively atmosphere.
Famous cathedral-side brasserie filled with religious statues, serving Belgian classics and beers in a unique historic setting.
Moderate by Western Europe standards: museums and transit are reasonable, while hotels and central dining cost more.
Service is usually included. Tipping is not required, but rounding up or leaving 5-10% for good service is appreciated. Round up taxi fares.
Official public transport app
Antwerp-Central -> Antwerp City Center
Find answers to the most common questions about traveling from Prague to Antwerp by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Antwerp, this guide helps you travel smarter and with confidence.

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