- Must visit
Uffizi Galleries
Florence’s premier art museum, famed for Renaissance masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. One of Italy’s essential museum visits.
Cheapest price
$199
Average price
$210
Fastest journey
7 h 41 m
Average duration
7 h 53 m
Trains per day
9
Distance
489 km
The best way to find a cheap train ticket from Nyon to Florence is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Nyon to Florence will cost around $210 if you buy it on the day, but the cheapest tickets can be found for only $199.
It's difficult to get from Nyon to Florence without transferring at least 3 times.
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Omio recommends booking the train as it is the most popular option from Nyon to Florence among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a train which can get you there in 6h 17m. The ticket price range depends on the travel mode: a bus costs an average of $62, and a train costs an average of $172.
Distance: 303 miles (489 km)
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$219 Average price | $211 Average price | $74 Average price Cheapest | $140 Average price (fuel + tolls) |
6h 47m Average total duration Fastest 6h 17m Onboard + 30m Additional time* | 11h 15m Average total duration 8h 15m Onboard + 3h 0m Additional time* | 16h 1m Average total duration 15h 31m Onboard + 30m Additional time* | 7h 8m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Nyon to Florence:
A bus is $138 (€113) less than a flight for this route with tickets for a flight from Nyon to Florence costing on average $211 (€173).
A bus is $145 (€119) less than a train for this route with tickets for a train from Nyon to Florence costing on average $219 (€179).
Other travel options to Florence take longer:
Flight takes on average 8h 15m.
Bus takes on average 15h 31m.
You'll arrive about 51m sooner (6h 17m by train vs 7h 8m by car). Tickets start at around $219 (€179) compared to roughly $140 (€115) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Nyon to Florence trains for today, Friday, June 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:10 AM Nyon | 5h54 | 11:04 AM Florence | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Nyon to Florence run on average 7 times per day, taking around 6h 17m. Cheap train tickets for this journey start at $172 (€141) but you can travel from only $62 (€51) by bus.
The earliest train runs at 02:03, the last at 16:55. The fastest train covers the 303 miles (489 km) distance in 5h 54m.
Distance 303 miles (489 km) |
Average train duration 6h 17m |
Cheapest ticket price $172 (€141) |
Trains per day 7 |
Fastest train 5h 54m |
First train 2:03 AM |
Last train 4:55 PM |
Cheapest Month Dec |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 35 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
Florence’s premier art museum, famed for Renaissance masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. One of Italy’s essential museum visits.
Best known for Michelangelo’s David, this museum also holds important Florentine paintings and sculpture. Advance booking is strongly advisable.
Vast palace museum complex with royal apartments, Palatine Gallery, and decorative arts. A major stop for art, Medici history, and grand interiors.
Florence’s monumental heart, where the cathedral, baptistery, and bell tower stand together. Essential for first-time visitors and photographers.
Historic civic square filled with sculpture and dominated by Palazzo Vecchio. One of the city’s most important and lively public spaces.
Florence’s most famous viewpoint, especially popular at sunset and widely shared on social media for its sweeping skyline panorama.
A Thick-Cut T-Bone Steak From Chianina Beef, Grilled Rare Over Coals. It Is Florence’s Signature Dish And A Classic Of Tuscan Cuisine.
A Traditional Florentine Street Food Made From The Fourth Stomach Of The Cow, Slow-Cooked In Broth And Served In A Roll, Often With Green Sauce.
A Rustic Tomato, Bread, Garlic, And Olive Oil Soup. It Is A Beloved Tuscan Dish That Turns Stale Bread Into Rich Comfort Food.
A Michelin-Starred Restaurant Offering Refined Tuscan Cuisine With Creative Technique, Elegant Service, And A Contemporary Fine-Dining Atmosphere.
A Small, Long-Running Florentine Favorite Known For Traditional Cooking, Especially Butter Chicken And Simple Tuscan Classics In An Old-School Setting.
A Historic, Casual Trattoria Near Mercato Centrale, Famous For Bistecca Alla Fiorentina, Tuscan Soups, And A Lively Local Atmosphere.
Generally moderate for Italy: museums and central hotels cost more, while casual food and coffee remain fairly affordable.
Service is often included or covered by a coperto. Tipping is not required, but leaving EUR 1-2 at cafes or 5-10% for excellent restaurant service is appreciated.
Official public transport app
Florence Santa Maria Novella, Florence -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from Nyon to Florence by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

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