- Must visit
Uffizi Gallery
World-famous gallery with Botticelli, Leonardo, and Michelangelo. Essential for understanding Renaissance painting and one of Florence’s top visits.
Cheapest price on Sep 19
$199
Average ticket price on Sep 19
$210
Fastest journey on Sep 19
7 h 41 m
Average journey duration on Sep 19
7 h 53 m
Trains on Sep 19
9
Distance
489 km
The best way to find a cheap train ticket from Nyon to Florence is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Nyon to Florence will cost around $210 if you buy it on the day, but the cheapest tickets can be found for only $199.
It's difficult to get from Nyon to Florence without transferring at least 3 times.
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Omio recommends booking the train as it is the most popular option from Nyon to Florence among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $85 For those with little time, consider booking a flight, which has an average total journey time of 4h 55m. Average ticket prices depend on the travel mode: a bus costs an average of $85, while a flight costs an average of $506.
Distance: 303 miles (489 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$393 Average price | $85 Average price Cheapest | $506 Average price | $142 Average price (fuel + tolls) |
7h 28m Average total duration 6h 58m Onboard + 30m Additional time* | 13h 51m Average total duration 13h 21m Onboard + 30m Additional time* | 4h 55m Average total duration Fastest 2h 55m Onboard + 2h 0m Additional time* | 7h 8m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Nyon to Florence:
A bus is $308 less than a train for this route with tickets for a train from Nyon to Florence costing on average $393.
A bus is $421 less than a flight for this route with tickets for a flight from Nyon to Florence costing on average $506.
Other travel options to Florence take longer:
Train takes on average 6h 58m.
Bus takes on average 13h 21m.
You'll arrive about 10m sooner (6h 58m by train vs 7h 8m by car). Tickets start at around $393 compared to roughly $142 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Nyon to Florence trains for today, Friday, September 18. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:10 AM Nyon | 5h54 | 11:04 AM Florence | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Nyon to Florence run on average 4 times per day, taking around 6h 58m. Cheap train tickets for this journey start at $370 but you can travel from only $73 by bus.
The earliest train runs at 02:03, the last at 16:55. The fastest train covers the 303 miles (489 km) distance in 5h 34m.
Distance 303 miles (489 km) |
Average train duration 6h 58m |
Cheapest ticket price $370 |
Trains per day 4 |
Fastest train 5h 34m |
First train 2:03 AM |
Last train 4:55 PM |
Cheapest Month Dec |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 35 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
World-famous gallery with Botticelli, Leonardo, and Michelangelo. Essential for understanding Renaissance painting and one of Florence’s top visits.
Houses Michelangelo’s David alongside major Renaissance sculptures. A must for first-time visitors interested in Florence’s artistic legacy.
Monastic museum with Fra Angelico frescoes and tranquil cells. Ideal for experiencing spiritual art in one of Florence’s most atmospheric spaces.
Florence’s monumental main square, framed by civic buildings and sculpture. A must for first impressions, history, and lively urban atmosphere.
The cathedral square is Florence’s ceremonial heart, surrounded by the Duomo, Baptistery, and bell tower. Essential for architecture lovers.
Riverside viewpoint with one of Florence’s classic panoramas. Best at sunset for sweeping views over the Arno, domes, and historic center.
Thick Florentine T-bone steak from Chianina beef, grilled rare over coals. It is the city's signature celebratory dish and a classic of Tuscan cuisine.
A rustic Tuscan bread soup with black cabbage, cannellini beans, vegetables, and olive oil. A beloved frugal dish rooted in Florentine home cooking.
A thick soup of bread, tomatoes, basil, garlic, and olive oil, served warm or at room temperature. It celebrates simple Tuscan ingredients and stale bread.
Three-Michelin-star fine dining by Enoteca Pinchiorri, known for refined Italian cuisine and an exceptional wine cellar. Elegant and formal.
Legendary casual stop for Lampredotto sandwiches and other tripe specialties. Simple, authentic street food experience in central Florence.
Historic steakhouse famed for Bistecca Alla Fiorentina and classic Tuscan dishes. Traditional, bustling atmosphere near Santa Croce.
Moderate for Italy: hotels in the center are pricier, but dining and transit are reasonable versus Rome or Venice.
Service is often included. Round up or leave €1-2 at cafés, 5-10% for great restaurant service, and round up taxi fares.
Official public transport app
Firenze Santa Maria Novella -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from Nyon to Florence by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

Most Nyon to Florence trains use the Lausanne to Firenze Santa Maria Novella station pair, with some services arriving at Firenze Campo di Marte. Use this guide to compare Nyon and Florence train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
Firenze Campo di Marte is 2 km from Florence city centre. Public transport options include:
Firenze Campo di Marte has practical services for this route, including Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, and Bike Rental.
Food options include: Moka Café
The ticket office is open Mon - Sun: 07:15 - 20:45.
Available at Firenze Campo di Marte: Taxis, WC.
Available at Firenze Campo di Marte: Bike Parking, Bike Rental.
Accessibility facilities are available at Firenze Campo di Marte: The station is fully accessible, with step-free access throughout the station.
Nearby hotels include Florence Stadium B&B, Hotel Villa Liana, Hotel della Robbia.
Here are some other resources that might have the information you need