- Must visit
Städel Museum
One of Germany’s leading art museums, with major European works from the Middle Ages to contemporary art on the Museumsufer.
Cheapest price
$106
Average price
$106
Fastest journey
6 h 1 m
Average duration
6 h 1 m
Trains per day
1
Distance
453 km
The best way to find a cheap train ticket from Nyon to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Nyon to Frankfurt am Main will cost around $106 if you buy it on the day, but the cheapest tickets can be found for only $106.
Of the 1 trains that leave Nyon for Frankfurt am Main on Mon, Jun 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct trains cover the 453 km distance in an average of 6 h 1 m but if you time it right, some trains will get you there in just 6 h 1 m .
On Mon, Jun 22 the slowest trains will take 6 h 1 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Nyon to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from $63. For those with little time consider booking a train which can get you there in 5h 44m. The ticket price range depends on the travel mode: a bus costs an average of $63, and a flight costs an average of $227.
Distance: 281 miles (453 km)
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$169 Average price | $266 Average price | $75 Average price Cheapest | $124 Average price (fuel + tolls) |
6h 14m Average total duration Fastest 5h 44m Onboard + 30m Additional time* | 9h 45m Average total duration 6h 45m Onboard + 3h 0m Additional time* | 19h 12m Average total duration 18h 42m Onboard + 30m Additional time* | 5h 39m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Nyon to Frankfurt am Main:
A bus is $94 (€77) less than a train for this route with tickets for a train from Nyon to Frankfurt am Main costing on average $169 (€138).
A bus is $191 (€156) less than a flight for this route with tickets for a flight from Nyon to Frankfurt am Main costing on average $266 (€218).
Other travel options to Frankfurt am Main take longer:
Flight takes on average 6h 45m.
Bus takes on average 18h 42m.
Tickets start at around $169 (€138) compared to roughly $124 (€101) in fuel and tolls — a saving of about $-45.16 (€-36.96). The journey takes 5h 44m versus 5h 39m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Nyon to Frankfurt am Main trains for tomorrow, Monday, June 22. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:39 AM Nyon | 6h01 | 2:40 PM Frankfurt am Main | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Nyon to Frankfurt am Main run on average 13 times per day, taking around 5h 44m. Cheap train tickets for this journey start at $106 (€87) but you can travel from only $63 (€51) by bus.
The earliest train runs at 00:56, the last at 23:24. The fastest train covers the 281 miles (453 km) distance in 6h 0m.
Distance 281 miles (453 km) |
Average train duration 5h 44m |
Cheapest ticket price $106 (€87) |
Trains per day 13 |
Fastest train 6h 0m |
First train 12:56 AM |
Last train 11:24 PM |
Cheapest Month Aug |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Oct - Dec |
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
One of Germany’s leading art museums, with major European works from the Middle Ages to contemporary art on the Museumsufer.
Major exhibition hall for temporary art shows, especially popular for high-profile international exhibitions in the old town area.
A favorite for families and science lovers, famous for dinosaur skeletons and extensive natural history collections.
Frankfurt’s historic central square, rebuilt with traditional character and surrounded by major sights, making it the city’s classic starting point.
The rebuilt old town quarter blends reconstructed timber houses, museums, shops, and lanes that have become highly popular with visitors.
A top skyline viewpoint that has become especially popular for sunset photos and sweeping views over the financial district.
A cold herb sauce made with seven fresh herbs, traditionally served with boiled eggs and potatoes. It is one of Frankfurt’s best-known regional specialties.
Frankfurt’s traditional tart apple wine, usually served in a ribbed glass. It is the city’s signature drink and central to local tavern culture.
A thin smoked pork sausage with protected regional status, typically served with mustard, bread, and potato salad. It is a classic Frankfurt snack.
One of Frankfurt’s best-known fine dining restaurants, offering refined modern cuisine in an elegant setting near the Palmengarten.
A long-established local tavern serving Hessian comfort food and apple wine. It is popular for an authentic neighborhood atmosphere and reliable regional dishes.
Frankfurt’s iconic indoor market hall with many established stalls for local sausages, cheeses, pastries, and casual regional bites in a lively setting.
Prices are high by German standards, especially hotels and dining in the centre, but transit and bakeries help keep daily costs manageable.
Service is usually included. Round up small bills, or tip about 5-10% in restaurants for good service. Round up taxis. Little or no tip is fine for counter service.
Official public transport app
Frankfurt am Main Flughafen -> Frankfurt (Main) Hauptbahnhof
Find answers to the most common questions about traveling from Nyon to Frankfurt am Main by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

Most Nyon to Frankfurt am Main trains use the Nyon to Frankfurt (Main) Hbf station pair, with some services arriving at Frankfurt Flughafen Fernbf. Use this guide to compare Nyon and Frankfurt am Main train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Nyon has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant du Marché, Café Ex Machina
Free. ATMs are available in the train station.
Ticket office support is available at Nyon. Information desks are located in the main hall.
Luggage storage is available at Nyon. Lost and found is available at the station.
Available at Nyon: Parking, Taxis, WC.
Available at Nyon: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Nyon: Ramps, restrooms.
Nearby hotels include Hotel Real, Hotel Le Rive, Base Nyon.
Frankfurt (Main) Hbf is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (Main) Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: asiagourmet, Burger King, Ciao Bella, Coffee Fellows, Crepes de France Express, dean&david, Starbucks, Uddin's Sky Sportsbar, McDonald's, Dunkin Donuts, & many more
Free Wi-Fi in the station. ATMs are available at Frankfurt (Main) Hbf.
Ticket office support is available at Frankfurt (Main) Hbf. Information desks are located opposite Platforms 12 and 13.
Luggage storage is luggage lockers are located in the main hall. Lost and found is available at the station.
Available at Frankfurt (Main) Hbf: Parking, Taxis, WC.
Available at Frankfurt (Main) Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Frankfurt (Main) Hbf: Step-free access and step markings. Contact the Mobility Service Centre at +49 3065212888 or [email protected].
Nearby hotels include Hotel Cristall, Grand Hotel Empire, Hotel Carlton.
Frankfurt Flughafen Fernbf is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt Flughafen Fernbf has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Käfer's, McDonald's, Asia Snack Box
Free. ATMs are available in the train station.
Ticket office support is available at Frankfurt Flughafen Fernbf. Information desks are located in the main hall.
Luggage storage is available at Frankfurt Flughafen Fernbf. Lost and found is available at the station.
Available at Frankfurt Flughafen Fernbf: Parking, Taxis, WC.
Available at Frankfurt Flughafen Fernbf: Bike Parking, Car Rental.
Accessibility facilities are available at Frankfurt Flughafen Fernbf: Elevators, ramps.
Nearby hotels include Sheraton Frankfurt Airport Hotel, Hilton Frankfurt Airport, Hilton Garden Inn Frankfurt Airport.
Frankfurt (M) Flughafen Regionalbf is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (M) Flughafen Regionalbf has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Käfer's, McDonald's, Asia Snack Box
Free. ATMs are available in the train station.
Ticket office support is available at Frankfurt (M) Flughafen Regionalbf. Information desks are located in the main hall.
Luggage storage is available at Frankfurt (M) Flughafen Regionalbf. Lost and found is available at the station.
Available at Frankfurt (M) Flughafen Regionalbf: Parking, Taxis, WC.
Available at Frankfurt (M) Flughafen Regionalbf: Bike Parking, Car Rental.
Accessibility facilities are available at Frankfurt (M) Flughafen Regionalbf: Elevators, ramps, restrooms.
Nearby hotels include Sheraton Frankfurt Airport Hotel, Hilton Frankfurt Airport, Steigenberger Airport Hotel.
Here are some other resources that might have the information you need