Travel Information
Compare bus, train, and flight for Nyon to Mannheim
Omio recommends booking the train as it is the most popular option from Nyon to Mannheim among Omio's users. If you are prioritising price take the bus with prices starting from €52. For those with little time consider booking a flight which can get you there in 4h 5m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of €52, and a flight costs an average of €202.
Distance: 238 miles (384 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€86 Average price | €250 Average price | €53 Average price Cheapest |
5h 45m Average total duration 5h 15m Onboard + 30m Additional time* | 7h 5m Average total duration Fastest 4h 5m Onboard + 3h 0m Additional time* | 14h 5m Average total duration 13h 35m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 1.2 - 2.3kg CO2 emissions | 0.4 - 1.0kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare prices and tickets Nyon to Mannheim by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Nyon to Mannheim trains with Omio?
Deutsche Bahn operates all train services from Nyon to Mannheim. Omio is the only official third party seller for Deutsche Bahn tickets.
Why book with Omio vs Deutsche Bahn?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Nyon to Mannheim.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Deutsche Bahn tickets can only be bought on Omio or Deutsche Bahn's website as Omio is the only official third party seller for Deutsche Bahn tickets. Trainline, RailEurope, and Rail.Ninja do not sell Deutsche Bahn tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Nyon to Mannheim.
Journey information
Overview: Train from Nyon to Mannheim
Trains from Nyon to Mannheim run on average 10 times per day, taking around 5h 15m. Cheap train tickets for this journey start at $70 (€56) but you can travel from only $65 (€52) by bus.
The earliest train runs at 04:22, the last at 19:09. The fastest train covers the 238 miles (384 km) distance in 5h 6m.
Distance 238 miles (384 km) |
Average train duration 5h 15m |
Cheapest ticket price $70 (€56) |
Trains per day 10 |
Fastest train 5h 6m |
First train 04:22 |
Last train 19:09 |
Train companies: Deutsche Bahn from Nyon to Mannheim trainsDeutsche Bahn trains will get you between Nyon and Mannheim from $65 (€52). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
FAQs: Trains from Nyon to Mannheim
Find answers to the most common questions about traveling from Nyon to Mannheim by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mannheim, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Nyon to Mannheim
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Route de St-Cergue.
- Restaurant du Marché
- Café Ex Machina
- Outside the main entrance.
- Ramps, restrooms.
- CHF 1
- Hotel Real
- Hotel Le Rive
- Base Nyon
- Located in the main hall
- 280 places, covered
- Europcar
- Avis
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-3 for trains to Geneva, Lausanne, and international destinations
- Train: SBB services
- Bus: Several local lines available
- Monday: 06:00 - 21:00
- Tuesday: 06:00 - 21:00
- Wednesday: 06:00 - 21:00
- Thursday: 06:00 - 21:00
- Friday: 06:00 - 21:00
- Saturday: 08:00 - 20:30
- Sunday: 08:00 - 20:30
- Safran Persisch-Afghanische Spezialitäten
- Corner
- Liman Döner
- Kaschmir-Tandoori
- Central
- Leonardo Hotel Mannheim City Center
- InterCityHotel Mannheim
- City Hotel
Most popular train connections from Nyon
More options for your journey from Nyon to Mannheim
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