Travel Information
Compare bus, train, and flight for Nyon to Florence
Omio recommends booking the bus as it is the most popular option from Nyon to Florence among Omio's users. If you are prioritising price take the bus with prices starting from $69. For those with little time consider booking a flight which can get you there in 6h 43m. The ticket price range depends on the travel mode: a bus costs an average of $69, and a flight costs an average of $133.
Distance: 303 miles (489 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$93 Average price Cheapest | $178 Average price | $153 Average price |
16h 15m Average total duration 15h 45m Onboard + 30m Additional time* | 9h 43m Average total duration Fastest 6h 43m Onboard + 3h 0m Additional time* | 8h 17m Average total duration 7h 47m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Nyon to Florence by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 21
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Mar 27
Journey information
Overview: Bus from Nyon to Florence
Buses from Nyon to Florence run on average 6 times per day, taking around 15h 45m. Cheap bus tickets for this journey start at $69 (€56) if you book in advance.
The earliest bus runs at 02:20, the last at 23:25. The fastest bus covers the 303 miles (489 km) distance in 11h 45m.
Distance 303 miles (489 km) |
Average bus duration 15h 45m |
Cheapest ticket price $69 (€56) |
Buses per day 6 |
Fastest bus 11h 45m |
First bus 02:20 |
Last bus 23:25 |
Cheapest month Feb |
Cheapest day Mon |
High season Jul - Sep |
Low season Jan - Mar |
Best day to book ahead 35 days |
Bus providers: Gruppo Di Maio, Sellitto from Nyon to FlorenceYou can travel by bus between Nyon to Florence with Gruppo Di Maio, Sellitto for as low as $69 (€56). When you search for schedules and tickets, Omio will show you the best journey
Gruppo Di Maio
Sellitto
FAQs: Bus from Nyon to Florence
Find answers to the most common questions about traveling from Nyon to Florence by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

- Florence Cathedral, an iconic Gothic structure known for its stunning dome designed by Brunelleschi
- Uffizi Gallery, a renowned art museum housing masterpieces by artists like Botticelli and Michelangelo
- Ponte Vecchio, a historic bridge famous for its shops and picturesque views over the Arno River
- Palazzo Vecchio, a medieval fortress-palace that serves as Florence's town hall and a museum
- Boboli Gardens, a vast and elegant park behind Pitti Palace featuring sculptures and fountains.
- Climb to Piazzale Michelangelo, a popular spot offering panoramic views of Florence's skyline
- Visit the Accademia Gallery to see Michelangelo's David
- Take a cooking class to learn how to make traditional Tuscan dishes
- Enjoy a wine tasting tour in the Chianti region
- Explore the vibrant San Lorenzo Market for local goods and delicacies.
popular bus stations
Popular bus stations from Nyon to Florence
- 06:00-22:00
- Free Wi-Fi
- Elevators, ramps
- Available in the station.
- Bus: 37, 72 Tram: T1
- 06:00-21:00
- Free Wi-Fi
- Available near the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 12, 13, 17 Train: Firenze Santa Maria Novella
Most popular bus connections from Nyon
More options for your journey from Nyon to Florence
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