- Recommended
Museo dell'Opera del Duomo
Cathedral complex museum displaying sculptures, treasures, and artworks from Piazza del Duomo, including pieces linked to Nicola and Giovanni Pisano.
Omio recommends booking the train as it is the most popular option from Napoli Afragola to Pisa among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 4h 11m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a train costs an average of $90.
Distance: 278 miles (448 km)
Most popular Train | Bus | Driving |
|---|---|---|
$104 Average price | $37 Average price Cheapest | $111 Average price (fuel + tolls) |
4h 41m Average total duration Fastest 4h 11m Onboard + 30m Additional time* | 10h 30m Average total duration 10h 0m Onboard + 30m Additional time* | 5h 15m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Napoli Afragola to Pisa:
A bus is $67 (€54) less than a train for this route with tickets for a train from Napoli Afragola to Pisa costing on average $104 (€84).
Other travel options to Pisa take longer:
Bus takes on average 10h 0m.
The journey is about 1h 4m faster (4h 11m by train vs 5h 15m by car) and roughly $7 (€6) cheaper once you factor in fuel and tolls ($104 (€84) vs $111 (€90)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Napoli Afragola to Pisa run on average 22 times per day, taking around 4h 11m. Cheap train tickets for this journey start at $90 (€72) but you can travel from only $24 (€19) by bus.
The earliest train runs at 08:10, the last at 18:53. The fastest train covers the 278 miles (448 km) distance in 4h 20m.
Distance 278 miles (448 km) |
Average train duration 4h 11m |
Cheapest ticket price $90 (€72) |
Trains per day 22 |
Fastest train 4h 20m |
First train 8:10 AM |
Last train 6:53 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Mon |
Least Busy Day Mon |
Discover the best of Pisa — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pisa trip today.
Cathedral complex museum displaying sculptures, treasures, and artworks from Piazza del Duomo, including pieces linked to Nicola and Giovanni Pisano.
Unique museum preserving the preparatory sinopia drawings for the Camposanto frescoes, offering insight into medieval mural techniques and restoration.
Major exhibition venue and art museum on the Arno, known for temporary shows, local collections, and its elegant restored palace setting.
Grand historic square once central to civic power, framed by notable palaces and often considered Pisa's second essential piazza after the Duomo area.
The riverside promenades along the Arno offer classic city views, elegant facades, and one of the best walks for photography, especially near sunset.
The monumental open space surrounding Pisa's most famous buildings, offering the classic postcard approach to the tower and cathedral complex.
A thin savory chickpea flour flatbread baked in a wood oven. It is a classic Tuscan street food and especially popular in Pisa and nearby coastal towns.
Fresh stuffed pasta typical of Tuscany, often filled with seasoned meat and served with rich ragù. It is a traditional festive dish found across the region.
Wide ribbon pasta served with slow-cooked wild boar sauce. This hearty Tuscan dish reflects the region’s rustic countryside cooking.
Well-known osteria near the center serving polished Tuscan classics, seasonal ingredients, and local wines in an elegant setting.
Classic informal trattoria loved for generous portions, straightforward Tuscan cooking, and good value near the center.
Established central Pisa restaurant known for traditional Tuscan dishes, pasta, and a refined but relaxed atmosphere.
Moderate by Italian standards. Cafes and casual dining are reasonable, but hotels and tourist-area restaurants cost more.
Service is often included or covered by a coperto. Tipping is not required, but rounding up or leaving EUR 1-5 for good service is appreciated. Taxis can be rounded up.
Official public transport app
Pisa Centrale, Pisa -> Piazza del Duomo, Pisa
Find answers to the most common questions about traveling from Napoli Afragola to Pisa by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Pisa, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need