- Recommended
Museo delle Sinopie
Pisa's main museum displays sculptures, paintings, manuscripts, and treasures from the cathedral complex and the city.
Omio recommends booking the flight as it is the most popular option from Madrid to Pisa among Omio's users. If you are prioritising price take the bus with prices starting from $94. For those with little time consider booking a flight which can get you there in 3h 6m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of $94, and a train costs an average of $268.
Distance: 757 miles (1219 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$268 Average price | $255 Average price | $164 Average price Cheapest | $316 Average price (fuel + tolls) |
46h 53m Average total duration 46h 23m Onboard + 30m Additional time* | 6h 6m Average total duration Fastest 3h 6m Onboard + 3h 0m Additional time* | 26h 52m Average total duration 26h 22m Onboard + 30m Additional time* | 16h 55m Average total duration (door-to-door) |
- CO2 emissions | 3.7 - 7.3kg CO2 emissions | 1.2 - 3.0kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Madrid to Pisa:
A bus is $91 (€75) less than a flight for this route with tickets for a flight from Madrid to Pisa costing on average $255 (€210).
A bus is $104 (€86) less than a train for this route with tickets for a train from Madrid to Pisa costing on average $268 (€221).
Other travel options to Pisa take longer:
Bus takes on average 26h 22m.
Train takes on average 46h 23m.
Tickets start at around $268 (€221) compared to roughly $316 (€261) in fuel and tolls — a saving of about $48 (€40). The journey takes 46h 23m versus 16h 55m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Madrid to Pisa run on average 1 times per day, taking around 46h 23m. Cheap train tickets for this journey start at $268 (€221) but you can travel from only $34 (€28) by flight.
The earliest train runs at 00:10, the last at 19:35. The fastest train covers the 757 miles (1219 km) distance in 46h 17m.
Distance 757 miles (1219 km) |
Average train duration 46h 23m |
Cheapest ticket price $268 (€221) |
Trains per day 1 |
Fastest train 46h 17m |
First train 12:10 AM |
Last train 7:35 PM |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 49 days |
Discover the best of Pisa — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pisa trip today.
Pisa's main museum displays sculptures, paintings, manuscripts, and treasures from the cathedral complex and the city.
Museum of preparatory sinopias from Camposanto frescoes, offering rare insight into medieval artistic techniques and restoration.
Museum in Palazzo Lanfranchi with 19th- and 20th-century art, including works by Tuscan artists and temporary exhibitions.
Pisa's UNESCO square gathers the Leaning Tower, cathedral, baptistery, and cemetery in one extraordinary monumental ensemble.
Historic square framed by noble buildings and the Scuola Normale, central to Pisa's medieval civic and political life.
Lively riverside promenade ideal for walking, with historic palaces, bridges, and classic views of the Arno through the city center.
Cecina is a thin wood-fired chickpea flour pancake, crisp outside and soft inside. It is a classic street food across Pisa and coastal Tuscany.
Pappa al pomodoro is a thick bread and tomato soup with garlic, basil, and olive oil. It is a beloved Tuscan peasant dish often found in Pisa.
Ribollita is a hearty Tuscan soup of bread, beans, and vegetables, traditionally reheated the next day. It reflects the frugal home cooking of the area.
Well-known traditional trattoria serving classic Tuscan plates and local specialties in a warm, rustic atmosphere.
Casual, established spot famous for cecina and pizza in a lively local setting. Ideal for trying one of Pisa’s signature foods.
Historic Pisan restaurant known for refined Tuscan seafood and meat dishes in an elegant, traditional setting near the center.
Moderate for Italy. Budget eats and local transit are reasonable, but hotels near the Leaning Tower and peak-season dining cost more than in smaller Tuscan towns.
Service is often included or minimal. Round up or leave €1-2 at cafes, 5-10% for great restaurant service, and round up taxi fares.
Find answers to the most common questions about traveling from Madrid to Pisa by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Pisa, this guide helps you travel smarter and with confidence.

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