The cheapest and fastest trains from Isernia to Florence
Cheapest price
$38
Average price
$39
Fastest journey
6 h 57 m
Average duration
7 h 1 m
Trains per day
2
Distance
343 km
The best way to find a cheap train ticket from Isernia to Florence is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Isernia to Florence will cost around $39 if you buy it on the day, but the cheapest tickets can be found for only $38.
Of the 2 trains that leave Isernia for Florence on Fri, Feb 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 06 the direct trains cover the 343 km distance in an average of 7 h 1 m but if you time it right, some trains will get you there in just 6 h 57 m .
On Fri, Feb 06 the slowest trains will take 7 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, and flight for Isernia to Florence
Omio recommends booking the train as it is the most popular option from Isernia to Florence among Omio's users. If you are prioritising price take the train with prices starting from €24. For those with little time consider booking a flight which can get you there in 2h 30m. The ticket price range depends on the travel mode: a train costs an average of €24, and a flight costs an average of €74.
Distance: 213 miles (343 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€34 Average price Cheapest | €43 Average price | €147 Average price |
5h 9m Average total duration 4h 39m Onboard + 30m Additional time* | 5h 44m Average total duration 5h 14m Onboard + 30m Additional time* | 5h 30m Average total duration Fastest 2h 30m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Isernia to Florence train times
The table below shows live departures for Isernia to Florence trains for tomorrow, Friday, February 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:55 PM Isernia | 7h05 | 8:00 PM Florence | 0 transfersDirect | |
![]() | 1:03 PM Isernia | 6h57 | 8:00 PM Florence | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Isernia to Florence by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Feb 12
Why should you book Isernia to Florence trains with Omio?
Why book with Omio vs Regionale?
- Compare with other providers: On Omio, you can not only buy tickets for Regionale, but also compare tickets for the likes of Intercity or Frecciarossa to find the best option for your trip from Isernia to Florence.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Regionale with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Isernia to Florence.
Why book with Omio over Raileurope?
- Official reseller: Regionale tickets can only be bought on Omio or Regionale's website as Omio is the only official third party seller for Regionale tickets. Raileurope do not sell Regionale tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Isernia to Florence.
Journey information
Overview: Train from Isernia to Florence
Trains from Isernia to Florence run on average 15 times per day, taking around 4h 39m. Cheap train tickets for this journey start at $31 (€24) but you can travel from only $27 (€22) by bus.
The earliest train runs at 05:00, the last at 23:07. The fastest train covers the 213 miles (343 km) distance in 7h 25m.
Distance 213 miles (343 km) |
Average train duration 4h 39m |
Cheapest ticket price $31 (€24) |
Trains per day 15 |
Fastest train 7h 25m |
First train 05:00 |
Last train 23:07 |
Train companies: Regionale, Intercity, Frecciarossa from Isernia to Florence trainsRegionale, Intercity, Frecciarossa trains will get you between Isernia and Florence from $27 (€22). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
Intercity
Frecciarossa
FAQs: Trains from Isernia to Florence
Find answers to the most common questions about traveling from Isernia to Florence by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Isernia to Florence
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Via Giovanni XXIII.
- Pasta e Pizza
- Ristorante da Adriano
- Outside the main entrance.
- Ramps.
- €0.50
- Grand Hotel Europa
- Hotel Ristorante Sayonara
- Hotel La Tequila
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for regional trains
- Bus: Several local lines available
- Train: Regional connections
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station, with access from Via dello Steccuto.
- Trattoria Fratelli Briganti
- Osteria di Poneta
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Raffaello
- Hotel Corolle
- Hotel Dalmazia
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-3 for regional trains
- Hall 2: platform 4-9 for intercity and high-speed trains
- Bus: Several lines available
- Tram: Line T1
- Mon - Sun: 07:15 - 20:45
- Moka Café
- The station is fully accessible, with step-free access throughout the station.
- Florence Stadium B&B
- Hotel Villa Liana
- Hotel della Robbia
- Mon - Sun: 07:15 - 20:45
- Bus lines: 12, 13, 33
- Train lines: FA, IC, ICN, R
Most popular train connections from Isernia
More options for your journey from Isernia to Florence
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