- Must visit
Vatican Museums
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and vast papal collections. Timed entry is strongly recommended due to heavy demand.
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The cheapest and fastest trains from Isernia to Rome
Showing times and prices for May 22
Cheapest price
$17
Average price
$23
Fastest journey
2 h 9 m
Average duration
2 h 18 m
Trains per day
15
Distance
149 km
Cheap tickets
The best way to find a cheap train ticket from Isernia to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Isernia to Rome will cost around $23 if you buy it on the day, but the cheapest tickets can be found for only $17.
Fast trains
Of the 15 trains that leave Isernia for Rome on Fri, May 22, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 22 the direct trains cover the 149 km distance in an average of 2 h 18 m but if you time it right, some trains will get you there in just 2 h 9 m .
On Fri, May 22 the slowest trains will take 2 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Autobus CB105 · Regionale 5812 · Regionale 126446:20 PM4h21Isernia station10:41 PMRome Termini$171One-way2 transfers- Autobus RM113 · Regionale Veloce 125984:50 AM3h01Isernia station7:51 AMRome Termini$171One-way1 transfer
- Regionale 233513:03 PM2h24Isernia station5:27 PMRome Termini$171One-way0 transfers
- Autobus CB101 · Regionale 5826 · Regionale 126363:20 PM5h00Isernia station8:20 PMRome Termini$171One-way2 transfers
- Regionale 233491:28 PM2h26Isernia station3:54 PMRome Tiburtina$171One-way0 transfers
- Regionale 233478:38 AM2h09Isernia station10:47 AMRome Termini$171One-way0 transfers
- Regionale 233416:40 AM2h13Isernia station8:53 AMRome Termini$171One-way0 transfers
- Regionale 233618:35 PM2h19Isernia station10:54 PMRome Termini$171One-way0 transfers
- Regionale 233513:03 PM2h24Isernia station5:27 PMRome Termini$171One-way0 transfers
- Autobus RM113+
FRECCIAROSSA 93044:50 AM2h25Isernia station7:15 AMRome Termini$271One-way1 transfer
Travel Information
Compare train and bus for Isernia to Rome
Omio recommends booking the train as it is the most popular option from Isernia to Rome among Omio's users. If you are prioritising price take the train with prices starting from $17. For those with little time consider booking a bus which can get you there in 2h 22m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a train costs an average of $17, and a bus costs an average of $10.
Distance: 92 miles (149 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$17 Average price Cheapest | $19 Average price | $50 Average price (fuel + tolls) |
3h 28m Average total duration 2h 58m Onboard + 30m Additional time* | 2h 52m Average total duration Fastest 2h 22m Onboard + 30m Additional time* | 2h 26m Average total duration (door-to-door) |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.4kg CO2 emissions | - CO2 emissions |
Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Isernia to Rome is a train with an average price of $17 (€14).
This is compared to other travel options from Isernia to Rome:
A train is $1 (€0.97) less than a bus for this route with tickets for a bus from Isernia to Rome costing on average $19 (€15).
The fastest way to travel from Isernia to Rome is by bus with an average journey time of 2h 22m.
Other travel options to Rome take longer:
Train takes on average 2h 58m.
It's helpful to compare your options as there are 2 ways to travel between Isernia and Rome including taking a train and bus.
We recommend using the train as it is the most popular way to get from Isernia to Rome among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Regionale.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Isernia to Rome train times
The table below shows live departures for Isernia to Rome trains for today, Thursday, May 21. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 6:35 PM Isernia | 2h19 | 8:54 PM Rome | 0 transfersDirect | |
| 7:35 PM Isernia | 2h19 | 9:54 PM Rome | 0 transfersDirect | |
| Friday, May 22 | |||||
| Autobus RM113+FRECCIAROSSA 9304 | 4:50 AM Isernia station | 2h25 | 7:15 AM Rome Termini | 1 transfer | |
| Autobus RM113 · Regionale Veloce 12598 | 4:50 AM Isernia station | 3h01 | 7:51 AM Rome Termini | 1 transfer | |
| Regionale 5179 · Regionale 5838 | 6:00 AM Isernia station | 2h48 | 8:48 AM Rome Termini | 1 transfer | |
| Regionale 23341 | 6:40 AM Isernia station | 2h13 | 8:53 AM Rome Termini | 0 transfersDirect | |
| Regionale 5181 · Regionale 5842 | 7:10 AM Isernia station | 3h03 | 10:13 AM Rome Termini | 1 transfer | |
| Regionale 5181+FRECCIAROSSA 8348 | 7:10 AM Isernia station | 3h03 | 10:13 AM Rome Termini | 1 transfer | |
| Regionale 23347 | 8:38 AM Isernia station | 2h09 | 10:47 AM Rome Termini | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Isernia to Rome by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Fri
May 22
May 22
Sat
May 23
May 23
Sun
May 24
May 24
Mon
May 25
May 25
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May 26
May 26
Wed
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May 27
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May 28
May 28
How far in advance should I book train tickets from Isernia to Rome?
The best time to book your train from Isernia to Rome is 35 days before departure. See how prices for trains change on the Isernia to Rome route.
Prices are for one-way tickets for one passenger from Isernia to Rome per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Isernia to Rome.
Trains
from $17Buses
from $15Journey information
Overview: Train from Isernia to Rome
ItalyItaly
Trains from Isernia to Rome run on average 9 times per day, taking around 2h 58m. Cheap train tickets for this journey start at $17 (€14) but you can travel from only $10 (€8) by bus.
There are 2 trains per day. The earliest train runs at 04:50, the last at 23:56. The fastest train covers the 92 miles (149 km) distance in 2h 7m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $10 (€8)
Distance 92 miles (149 km) |
Average train duration 2h 58m |
Cheapest ticket price $17 (€14) |
Trains per day 9 |
Direct trains 2 |
Fastest train 2h 7m |
First train 4:50 AM |
Last train 11:56 PM |
Cheapest Month Jun |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Mon |
Best time to book 49 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $10 (€8)
Train companies: Regionale, Intercity from Isernia to Rome trainsRegionale, Intercity trains will get you between Isernia and Rome from $10 (€8). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
2h 7m
Cheapest Price
$17 (€14)
Regionale frequency
5 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
3h 15m
Cheapest Price
$22 (€18)
Intercity frequency
1 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
Complete guide to Rome
Things to do in Rome
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
- Must visit
Galleria Borghese
Premier art gallery in Villa Borghese, known for Bernini sculptures and masterpieces by Caravaggio and Raphael. Advance reservation is typically required.
- Recommended
Capitoline Museums
Rome’s historic civic museums on Capitoline Hill, featuring ancient Roman sculpture, bronzes, and sweeping views over the Forum.
- Must visit
Piazza Navona
Elegant baroque square famed for Bernini fountains, church facades, and lively street atmosphere. A classic place to stroll day or night.
- Must visit
Trastevere
Beloved neighborhood of narrow lanes, ivy-clad buildings, and vibrant evening life, popular with both locals and visitors.
- Must visit
Spanish Steps
Iconic monumental staircase and social gathering point linking Piazza di Spagna with Trinità dei Monti, especially photogenic at golden hour.
- Vegetarian
Cacio e Pepe
Iconic Roman pasta made with tonnarelli or spaghetti, Pecorino Romano, and black pepper. A minimalist classic strongly associated with Rome.
Carbonara
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. It is one of the city’s most famous traditional dishes.
Amatriciana
Roman favorite of pasta dressed with tomato, guanciale, Pecorino Romano, and chili or black pepper. Deeply rooted in local trattoria culture.
La Pergola
Rome’s landmark fine-dining restaurant offering refined Italian cuisine, luxury service, and panoramic city views. Best for a splurge experience.
Armando al Pantheon
Historic trattoria near the Pantheon, famous for classic Roman dishes such as carbonara, amatriciana, and seasonal specialties. Traditional and intimate.
Roscioli Salumeria con Cucina
Celebrated central Rome dining room known for Roman pasta, cured meats, cheeses, and an excellent wine list. Busy, polished, and very popular.
Euro
Compared with many Western European capitals, Rome is moderate overall: budget dining is accessible, but central hotels and tourist-area restaurants can be costly.
Average meal costs
- Budget
- EUR 8-15 for pizza al taglio, panini, or simple trattoria meals.
- Mid-range
- EUR 20-40 per person for a meal at a mid-range restaurant.
- Fine dining
- EUR 80+ per person at upscale restaurants, often more with wine.
- Coffee
- EUR 1.20-2.50 for espresso or cappuccino, depending on bar service or table service.
Tipping culture
Service is often included or reflected in menu prices, and tipping is not as obligatory as in some countries. In restaurants, rounding up the bill or leaving about EUR 1-5 for good service is common;
TicketAppy
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.50
- Day pass
- EUR 7.00
To the city center
Rome Termini -> Piazza Venezia, Rome
- Distance
- 2 km
- Travel time
- 10 min
- Validate paper tickets at the start of your journey; digital tickets must be activated before boarding.
- On buses and trams, contactless card payment is available on many vehicles, but not all, so carry a valid ticket as backup.
FAQs: Trains from Isernia to Rome
Find answers to the most common questions about traveling from Isernia to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.
Train ticket prices from Isernia to Rome can vary. The cheapest ticket starts at $17 (€14), while the average price is around $17 (€14).
The train from Isernia to Rome takes 2h 7m and runs 9 per day.
The first train from Isernia to Rome leaves at 4:50 AM.
The distance by train from Isernia to Rome is 92 miles (149 km).
The last train from Isernia to Rome leaves at 11:56 PM.
There is no high speed train available from Isernia to Rome.
Yes, there is a direct train from Isernia to Rome. This service operates 2 times per day, provided by Regionale.
Unfortunately, there is no night train available from Isernia to Rome.
The train station in Isernia that goes to Rome is Isernia station, which connects to Rome Termini.
The cheapest way to get from Isernia to Rome is by bus, with a cost of around $10 (€8).
The train journey from Isernia to Rome offers some scenic views, particularly as it traverses the beautiful rolling hills and picturesque landscapes of central Italy. Passengers can enjoy glimpses of charming countryside, small towns, and lush greenery, providing a pleasant visual experience during the trip.
A day trip from Isernia to Rome is not feasible as the journey takes 2h 7m, and there are 8 trains per day covering a distance of 92 miles (149 km).
In Rome, explore Trastevere's charming streets and nightlife, stroll through Villa Borghese's parks and museums, enjoy gelato at the lively Piazza Navona, and visit the Spanish Steps for views and people-watching. Discover the ancient Catacombs with guided tours, and don't miss the best sights: the iconic Colosseum, the art-filled Vatican Museums including the Sistine Chapel, the ruins of the Roman Forum, the well-preserved Pantheon, and the famous Trevi Fountain where you can toss a coin for good luck.
To experience Rome's main attractions, a stay of 3 to 4 days is generally recommended, allowing time to visit landmarks like the Colosseum, Vatican City, and explore local neighborhoods.
Yes, you can take the train from Isernia to Rome.
Since both Isernia and Rome are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Rome include Civitavecchia, Fiumicino, Tivoli, Orvieto, Anzio.
We recommend using the train as it is the most popular way to get from Isernia to Rome among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Rome, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, major landmarks, and popular squares. Common scams include unofficial taxi drivers overcharging and street vendors selling counterfeit goods. It's advisable to use authorized taxis, keep valuables secure, and be wary of distraction techniques used by scammers in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Isernia to Rome
Isernia
Rome
The major train station for departures in Isernia is Isernia. Find all the information you need to know about services, amenities and connections at Isernia for your trip from Isernia to Rome.
Amenities at train station
Wifi
Lockers
Parking
Dining
Taxis
Accessibility
WC
Hotel
Lost and Found Office
Ticket Office
Bike Parking
Information Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 8:00 PM Monday - Sunday
Number of platforms
2Wifi
- Free
Parking
- Parking is available 24/7 with access from Via Giovanni XXIII.
Dining
- Pasta e Pizza
- Ristorante da Adriano
Taxis
- Outside the main entrance.
Accessibility
- Ramps.
WC
- €0.50
Hotel
- Grand Hotel Europa
- Hotel Ristorante Sayonara
- Hotel La Tequila
Lost and Found Office
- Located in the main hall
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for regional trains
Public transit options for Isernia
- Bus: Several local lines available
- Train: Regional connections
The major train station for arrivals in Rome is Roma Termini. Find all the information you need to know about services, amenities and connections at Roma Termini for your journey to Rome from Isernia.
Amenities at train station
WifiLockersParkingDining
ATMTaxisAccessibilityWCHotelTicket OfficeBike Parking
Car RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 06:30 - 22:00
Distance to city center
1 kmWifi
- Free WiFi in the station.
Lockers
- Provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Dining
- Acafe
- Moka Café
- Roadhouse Grill
- McDonald's
- Gusto
- Chef Express
- Coop Minimarket
- Mercato Centrale
Accessibility
- The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Hotel
- Archi di Roma Guest House
- Gemma di Roma
- The Liberty Boutique Hotel
Ticket Office
- Mon - Sun: 06:30 - 22:00
Information Desk
- Located near Platform 24.
Public transit options for Roma Termini
- Metro lines: A (red), B (blue)
- Bus lines: 5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
- Tram lines: 5, 14
- Train lines: Italo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 06:35 - 20:20
Distance to city center
4 kmWifi
- Free, limited Wi-Fi available in the station for 15 minutes.
Lockers
- Luggage lockers are located in the station lobby.
Dining
- Rock n’ Coffee Roma
- Arabian Kebab
- Ingredienti
- McDonald’s
- Numb's Bakery Café
Accessibility
- Accessible facilities include elevators and escalators.
Hotel
- B&B Rome Tiburtina
- B&B Alba Domus Roma
- Hotel delle Province
Ticket Office
- Mon - Sun: 06:35 - 20:20
Information Desk
- Located inside the main terminal.
Public transit options for Roma Tiburtina
- Metro lines: LB
- Bus lines: 62, 71, 111, 111F, 120F, 135, 163, 168, 211, 309, 409, n409, n041, C2, C3, Airport Shuttle
- Train lines: FR, FA, IC, REG, FL1, FL2, FL3
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
2 kmNumber of platforms
5Wifi
- Free
Parking
- Parking is available near the station, with access from Via di Monte Verde.
Dining
- Trattoria Da Enzo al 29
- Osteria der Belli
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps, restrooms.
WC
- €1
Hotel
- Hotel San Francesco
- Hotel Ripa Roma
- Hotel Santa Maria
Lost and Found Office
- Located in the main hall
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-5 for regional and local trains
Public transit options for Roma Trastevere
- Tram: Line 8
- Bus: Several lines available
Most popular train connections from Isernia
More options for your journey from Isernia to Rome
Here are some other resources that might have the information you need
Most popular trains to and from Rome and Isernia
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