Isernia to Milan Centrale train with Italo

Wed, Sep 30
+ Add return
Intercity
Frecciarossa
Italo
Intercity Notte
Regionale
2,000+ travel companies
Intercity
Frecciarossa
Italo
Intercity Notte
Regionale
2,000+ travel companies
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The cheapest and fastest trains from Isernia to Milan Centrale

Showing times, prices and bookable tickets for Sep 30

Cheapest price on Sep 30

$99

Average ticket price on Sep 30

$99

Fastest journey on Sep 30

13 h 5 m

Average journey duration on Sep 30

13 h 5 m

Trains on Sep 30

1

Distance

592 km

Cheap tickets

The best way to find a cheap train ticket from Isernia to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Isernia to Milan Centrale will cost around $99 if you buy it on the day, but the cheapest tickets can be found for only $99.

Fast trains

On Wed, Sep 30, we found 1 trains from Isernia to Milan Centrale, including 1 direct services.

On Wed, Sep 30 the direct trains cover the 592 km distance in an average of 13 h 5 m but if you time it right, some trains will get you there in just 13 h 5 m .

On Wed, Sep 30 the slowest trains will take 13 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Intercity Notte
    5:00 PM13h05
    Isernia
    6:05 AMMilan Centrale
    $991One-way
    0 transfers

Live departures

Isernia to Milan Centrale train times

The table below shows live departures for Isernia to Milan Centrale trains for tomorrow, Wednesday, September 30. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Intercity Notte5:00 PM Isernia
13h05
6:05 AM Milan Centrale0 transfersDirect

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Isernia to Milan Centrale by train

Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Sep 30
Thu
Oct 01
Fri
Oct 02
Sat
Oct 03
Sun
Oct 04
Mon
Oct 05
Tue
Oct 06

Why should you book Isernia to Milan Centrale trains with Omio?

Intercity as well as Frecciarossa, Italo, Intercity Notte and more offer trains services from Isernia to Milan Centrale.
Omio is the only official third party seller for Intercity tickets.

Why book with Omio vs Intercity?

  • Compare with other providers: On Omio, you can not only buy tickets for Intercity, but also compare tickets for the likes of Frecciarossa, Italo or Intercity Notte to find the best option for your trip from Isernia to Milan Centrale.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Train from Isernia to Milan Centrale

ItalyItaly
ItalyItaly
Icon of train

Trains from Isernia to Milan Centrale run on average 22 times per day, taking around 6h 26m. Cheap train tickets for this journey start at $17 if you book in advance.

The earliest train runs at 06:40, the last at 20:35. The fastest train covers the 367 miles (592 km) distance in 5h 18m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
367 miles (592 km)
Average train duration
6h 26m
Cheapest ticket price
$17
Trains per day
22
Fastest train
5h 18m
First train
6:40 AM
Last train
8:35 PM
Cheapest Month
Sep
Cheapest Day
Thu
High Season
Apr - Jun
Low Season
Jul - Sep
Busiest Day
Sat
Least Busy Day
Sat
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Train companies: Italo, Frecciarossa, Intercity, Intercity Notte from Isernia to Milan Centrale trainsItalo, Frecciarossa, Intercity, Intercity Notte trains will get you between Isernia and Milan Centrale from $17. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Italo

About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Italo Duration
5h 18m
Cheapest Italo Price
$17
Italo frequency
14 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Learn more about Italo

Frecciarossa

About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Frecciarossa Duration
5h 18m
Cheapest Frecciarossa Price
$120
Frecciarossa frequency
5 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Learn more about Frecciarossa

Intercity

About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Intercity Duration
9h 52m
Cheapest Intercity Price
$96
Intercity frequency
2 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone

Intercity Notte

About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Average Intercity Notte Duration
10h 7m
Cheapest Intercity Notte Price
$98
Intercity Notte frequency
1 a day
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone

FAQs: Trains from Isernia to Milan Centrale

Find answers to the most common questions about traveling from Isernia to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Isernia to Milan Centrale can vary. The cheapest ticket starts at $17, while the average price is around $60.
The train from Isernia to Milan Centrale takes 5h 18m and runs 22 per day.
The distance by train from Isernia to Milan Centrale is 367 miles (592 km).
The first train from Isernia to Milan Centrale leaves at 6:40 AM.
The last train from Isernia to Milan Centrale leaves at 8:35 PM.
Yes, there is a high-speed train from Isernia to Milan Centrale.
There is no direct train service currently available from Isernia to Milan Centrale.
Yes, there is a night train from Isernia to Milan Centrale.
The train journey from Isernia to Milano Centrale offers varied scenery, featuring the picturesque landscapes of the Apennine Mountains, charming rural villages, and the lush countryside of northern Italy, providing a pleasant visual experience.
Yes, you can take the train from Isernia to Milan Centrale.
Popular day trips by train from Milan Centrale include Como, Varenna, Bergamo, Verona, Turin.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Isernia to Milan Centrale

Most Isernia to Milan Centrale trains use the Isernia to Milano Centrale station pair. Use this guide to compare Isernia and Milan Centrale train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Isernia
Arrival train stations in Milan
IserniaPiazza della Repubblica, 86170 Isernia IS, Italy+39 0865 4131WifiLockersParkingDiningTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingInformation DeskLuggage Carts
City-centre transport

Getting to Isernia from Isernia city centre

Bus31 · 1m · $4

Isernia train station facilities and services

Isernia has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.

Food and drink

Food options include: Pasta e Pizza, Ristorante da Adriano

Wi-Fi and ATMs

Free.

Tickets and information

Ticket office support is available at Isernia. Information desks are located in the main hall.

Luggage and lost property

Luggage storage is available at Isernia. Lost and found is available at the station.

Parking, taxis and toilets

Available at Isernia: Parking, Taxis, WC.

Bike and car services

Available at Isernia: Bike Parking.

Accessibility

Accessibility facilities are available at Isernia: Ramps.

Shops, hotels and contact

Nearby hotels include Grand Hotel Europa, Hotel Ristorante Sayonara, Hotel La Tequila.

More about Isernia

More options for your journey from Isernia to Milan Centrale

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