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The cheapest and fastest trains from Isernia to Milan Centrale
Showing times and prices for Mar 24
Cheapest price
$65
Average price
$65
Fastest journey
12 h 15 m
Average duration
12 h 15 m
Trains per day
1
Distance
592 km
Cheap tickets
The best way to find a cheap train ticket from Isernia to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Isernia to Milan Centrale will cost around $65 if you buy it on the day, but the cheapest tickets can be found for only $65.
Fast trains
Of the 1 trains that leave Isernia for Milan Centrale on Tue, Mar 24, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 24 the direct trains cover the 592 km distance in an average of 12 h 15 m but if you time it right, some trains will get you there in just 12 h 15 m .
On Tue, Mar 24 the slowest trains will take 12 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
06:10AM12h15
Isernia06:25PMMilan Centrale
$651One-way
0 transfers
06:10AM12h15
Isernia06:25PMMilan Centrale
$651One-way
0 transfers
Travel Information
Compare train, bus, and flight for Isernia to Milan Centrale
Omio recommends booking the train as it is the most popular option from Isernia to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $23. For those with little time consider booking a flight which can get you there in 1h 27m. The ticket price range depends on the travel mode: a bus costs an average of $23, and a train costs an average of $59.
Distance: 367 miles (592 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
$102 Average price | $69 Average price | $59 Average price Cheapest |
7h 11m Average total duration 6h 41m Onboard + 30m Additional time* | 4h 27m Average total duration Fastest 1h 27m Onboard + 3h 0m Additional time* | 14h 54m Average total duration 14h 24m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Isernia to Milan Centrale train times
The table below shows live departures for Isernia to Milan Centrale trains for today, Monday, March 23. You can also manually refresh the results below to see updated train journeys.
Last updated at 4:51 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 5:10 AM Isernia | 6h14 | 11:24 AM Milan Centrale | 0 transfersDirect | |
| 5:43 AM Isernia | 7h15 | 12:58 PM Milan Centrale | 0 transfersDirect | |
 | 5:00 PM Isernia | 13h05 | 6:05 AM Milan Centrale | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Isernia to Milan Centrale by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Mar 24
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Why should you book Isernia to Milan Centrale trains with Omio?
Italo as well as Frecciarossa, Intercity, Regionale and more offer trains services from Isernia to Milan Centrale.
Omio is the only official third party seller for Italo tickets.
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Intercity or Regionale to find the best option for your trip from Isernia to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Isernia to Milan Centrale.
Journey information
Overview: Train from Isernia to Milan Centrale
ItalyItaly
Trains from Isernia to Milan Centrale run on average 7 times per day, taking around 6h 41m. Cheap train tickets for this journey start at $59 (€48) but you can travel from only $23 (€19) by bus.
The earliest train runs at 05:10, the last at 17:10. The fastest train covers the 367 miles (592 km) distance in 6h 14m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $23 (€19)
Distance 367 miles (592 km) |
Average train duration 6h 41m |
Cheapest ticket price $59 (€48) |
Trains per day 7 |
Fastest train 6h 14m |
First train 05:10 |
Last train 17:10 |
Cheapest month Mar |
Cheapest day Wed |
High season Oct - Dec |
Low season Jan - Mar |
Busiest day Sat |
Least busy day Sat |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $23 (€19)
Train companies: Italo, Frecciarossa, Intercity, Regionale from Isernia to Milan Centrale trainsItalo, Frecciarossa, Intercity, Regionale trains will get you between Isernia and Milan Centrale from $23 (€19). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
6h 14m
Cheapest Price
$111 (€91)
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
12h 15m
Cheapest Price
$59 (€48)
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
15h 18m
Cheapest Price
$186 (€151)
Regionale frequency
1 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
FAQs: Trains from Isernia to Milan Centrale
Find answers to the most common questions about traveling from Isernia to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.
Train ticket prices from Isernia to Milan Centrale can vary. The cheapest ticket starts at $59 (€48), while the average price is around $102 (€83).
The train from Isernia to Milan Centrale takes 6h 14m and runs 7 per day.
The distance by train from Isernia to Milan Centrale is 367 miles (592 km).
The first train from Isernia to Milan Centrale leaves at 5:10 AM.
The last train from Isernia to Milan Centrale leaves at 5:10 PM.
Yes, there is a high-speed train from Isernia to Milan Centrale.
There is no direct train service currently available from Isernia to Milan Centrale.
Unfortunately, there is no night train available from Isernia to Milan Centrale.
The cheapest way to get from Isernia to Milan Centrale is by bus, with a cost of around $23 (€19).
The train journey from Isernia to Milano Centrale offers varied scenery, featuring the picturesque landscapes of the Apennine Mountains, charming rural villages, and the lush countryside of northern Italy, providing a pleasant visual experience.
A day trip from Isernia to Milano Centrale is not feasible, as the journey duration is 6h 14m. However, there are 9 train trips per day available for this route.
Yes, you can take the train from Isernia to Milan Centrale.
popular train stations
Popular train stations from Isernia to Milan Centrale
Isernia
Milan
The major train station for departures in Isernia is Isernia. Find all the information you need to know about services, amenities and connections at Isernia for your trip from Isernia to Milan.
Amenities at train station
Wifi
Lockers
Parking
Dining
Taxis
Accessibility
WC
Hotel
Lost and Found Office
Ticket Office
Bike Parking
Information Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 8:00 PM Monday - Sunday
Number of platforms
2Wifi
- Free
Parking
- Parking is available 24/7 with access from Via Giovanni XXIII.
Dining
- Pasta e Pizza
- Ristorante da Adriano
Taxis
- Outside the main entrance.
Accessibility
- Ramps.
WC
- €0.50
Hotel
- Grand Hotel Europa
- Hotel Ristorante Sayonara
- Hotel La Tequila
Lost and Found Office
- Located in the main hall
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for regional trains
Public transit options for Isernia
- Bus: Several local lines available
- Train: Regional connections
The major train station for arrivals in Milan is Milano Centrale. Find all the information you need to know about services, amenities and connections at Milano Centrale for your journey to Milan from Isernia.
Amenities at train station
WifiLockersParkingDining
ATMTaxisAccessibilityWCHotelTicket OfficeBike Parking
Bike Rental
Car RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 05:50 - 22:20
Distance to city center
2 kmWifi
- Free WiFi in the station.
Lockers
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
Dining
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
Accessibility
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
Hotel
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
Ticket Office
- Mon - Sun: 05:50 - 22:20
Information Desk
- Located next to the ticket office on the ground floor in the shopping gallery.
Public transit options for Milano Centrale
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Isernia
More options for your journey from Isernia to Milan Centrale
Here are some other resources that might have the information you need
Most popular trains to and from Milan Centrale and Isernia
Most popular train connections to Milan Centrale
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