The cheapest and fastest trains from Florence Santa Maria Novella to Lyon Part Dieu
Cheapest price
$140
Average price
$239
Fastest journey
7 h 7 m
Average duration
7 h 56 m
Trains per day
26
Distance
550 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Lyon Part Dieu is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Lyon Part Dieu will cost around $239 if you buy it on the day, but the cheapest tickets can be found for only $140.
It's difficult to get from Florence Santa Maria Novella to Lyon Part Dieu without transferring at least once.
Intercity 580+
FRECCIAROSSA 1000 92968:21 AM12h11Florence Santa Maria Novella8:32 PMLyon Part Dieu$1401One-way1 transfer
Regionale 18662 · Regionale 17820+
Intercity 606+
FRECCIAROSSA 1000 92969:47 AM10h45Florence Santa Maria Novella8:32 PMLyon Part Dieu$1501One-way3 transfers
Regionale 17800 · Regionale Veloce TTPER 2460+
FRECCIAROSSA 1000 92964:32 AM16h00Florence Santa Maria Novella8:32 PMLyon Part Dieu$1501One-way2 transfers
Regionale 18502 · Regionale 17808 · Regionale Veloce TTPER 2466+
FRECCIAROSSA 1000 92967:09 AM13h23Florence Santa Maria Novella8:32 PMLyon Part Dieu$1501One-way3 transfers
Regionale 18508 · Regionale 17818 · Regionale Veloce TTPER 2470+
FRECCIAROSSA 1000 92969:09 AM11h23Florence Santa Maria Novella8:32 PMLyon Part Dieu$1501One-way3 transfers
9928+
FRECCIAROSSA 1000 92961:25 PM7h07Florence Santa Maria Novella8:32 PMLyon Part Dieu$4311One-way1 transfer
FRECCIAROSSA 9514+
FRECCIAROSSA 1000 929612:55 PM7h37Florence Santa Maria Novella8:32 PMLyon Part Dieu$1881One-way1 transfer
9924+
FRECCIAROSSA 1000 929612:25 PM8h07Florence Santa Maria Novella8:32 PMLyon Part Dieu$4511One-way1 transfer
FRECCIAROSSA 9416 · FRECCIAROSSA 8814+
FRECCIAROSSA 1000 929612:20 PM8h12Florence Santa Maria Novella8:32 PMLyon Part Dieu$1961One-way2 transfers
FRECCIAROSSA 9524+
FRECCIAROSSA 1000 929611:55 AM8h37Florence Santa Maria Novella8:32 PMLyon Part Dieu$1681One-way1 transfer
Travel Information
Compare train, bus, and flight for Florence Santa Maria Novella to Lyon Part Dieu
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Lyon Part Dieu among Omio's users. If you are prioritising price take the bus with prices starting from $19. For those with little time consider booking a flight which can get you there in 5h 2m. The ticket price range depends on the travel mode: a bus costs an average of $19, and a flight costs an average of $77.
Distance: 341 miles (550 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$153 Average price | $50 Average price Cheapest | $198 Average price | $321 Average price (fuel + tolls) |
7h 9m Average total duration 6h 39m Onboard + 30m Additional time* | 8h 57m Average total duration 8h 27m Onboard + 30m Additional time* | 8h 2m Average total duration Fastest 5h 2m Onboard + 3h 0m Additional time* | 7h 24m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence Santa Maria Novella to Lyon Part Dieu:
A bus is $102 (€82) less than a train for this route with tickets for a train from Florence Santa Maria Novella to Lyon Part Dieu costing on average $153 (€123).
A bus is $148 (€119) less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Lyon Part Dieu costing on average $198 (€159).
Other travel options to Lyon Part Dieu take longer:
Train takes on average 6h 39m.
Bus takes on average 8h 27m.
The journey is about 45m faster (6h 39m by train vs 7h 24m by car) and roughly $169 (€136) cheaper once you factor in fuel and tolls ($153 (€123) vs $321 (€258)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Live departures
Florence Santa Maria Novella to Lyon Part Dieu train times
The table below shows live departures for Florence Santa Maria Novella to Lyon Part Dieu trains for today, Wednesday, August 26. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 17800 · Regionale Veloce TTPER 2460+ FRECCIAROSSA 1000 9296 | 4:32 AM Florence Santa Maria Novella | 16h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 17800 · Regionale TTPER 2070+ Intercity 652+ FRECCIAROSSA 1000 9296 | 4:32 AM Florence Santa Maria Novella | 16h00 | 8:32 PM Lyon Part Dieu | 3 transfers | |
Regionale 18654 · Regionale 17804 · Regionale Veloce TTPER 2462+ FRECCIAROSSA 1000 9296 | 5:41 AM Florence Santa Maria Novella | 14h51 | 8:32 PM Lyon Part Dieu | 3 transfers | |
FRECCIAROSSA 9504+ FRECCIAROSSA 1000 9296 | 6:55 AM Florence Santa Maria Novella | 13h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale 18502 · Regionale 17808 · Regionale Veloce TTPER 2466+ FRECCIAROSSA 1000 9296 | 7:09 AM Florence Santa Maria Novella | 13h23 | 8:32 PM Lyon Part Dieu | 3 transfers | |
FRECCIAROSSA 9400 · FRECCIAROSSA 9802+ FRECCIAROSSA 1000 9296 | 7:20 AM Florence Santa Maria Novella | 13h12 | 8:32 PM Lyon Part Dieu | 2 transfers | |
9904+ FRECCIAROSSA 1000 9296 | 7:25 AM Florence Santa Maria Novella | 13h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9508+ FRECCIAROSSA 1000 9296 | 7:55 AM Florence Santa Maria Novella | 12h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9404 · FRECCIAROSSA 9610+ FRECCIAROSSA 1000 9296 | 8:20 AM Florence Santa Maria Novella | 12h12 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Intercity 580+ FRECCIAROSSA 1000 9296 | 8:21 AM Florence Santa Maria Novella | 12h11 | 8:32 PM Lyon Part Dieu | 1 transfer | |
9908+ FRECCIAROSSA 1000 9296 | 8:25 AM Florence Santa Maria Novella | 12h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale 18466 · Regionale 17816+ Intercity 604+ FRECCIAROSSA 1000 9296 | 8:37 AM Florence Santa Maria Novella | 11h55 | 8:32 PM Lyon Part Dieu | 3 transfers | |
FRECCIAROSSA 9512+ FRECCIAROSSA 1000 9296 | 8:55 AM Florence Santa Maria Novella | 11h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale 18508 · Regionale 17818 · Regionale Veloce TTPER 2470+ FRECCIAROSSA 1000 9296 | 9:09 AM Florence Santa Maria Novella | 11h23 | 8:32 PM Lyon Part Dieu | 3 transfers | |
9912+ FRECCIAROSSA 1000 9296 | 9:25 AM Florence Santa Maria Novella | 11h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale 18662 · Regionale 17820+ Intercity 606+ FRECCIAROSSA 1000 9296 | 9:47 AM Florence Santa Maria Novella | 10h45 | 8:32 PM Lyon Part Dieu | 3 transfers | |
FRECCIAROSSA 9516+ FRECCIAROSSA 1000 9296 | 9:55 AM Florence Santa Maria Novella | 10h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9490 · FRECCIAROSSA 8810+ FRECCIAROSSA 1000 9296 | 10:20 AM Florence Santa Maria Novella | 10h12 | 8:32 PM Lyon Part Dieu | 2 transfers | |
9916+ FRECCIAROSSA 1000 9296 | 10:25 AM Florence Santa Maria Novella | 10h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9520+ FRECCIAROSSA 1000 9296 | 10:55 AM Florence Santa Maria Novella | 9h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9414 · FRECCIAROSSA 9806+ FRECCIAROSSA 1000 9296 | 11:20 AM Florence Santa Maria Novella | 9h12 | 8:32 PM Lyon Part Dieu | 2 transfers | |
9920+ FRECCIAROSSA 1000 9296 | 11:25 AM Florence Santa Maria Novella | 9h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9524+ FRECCIAROSSA 1000 9296 | 11:55 AM Florence Santa Maria Novella | 8h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9416 · FRECCIAROSSA 8814+ FRECCIAROSSA 1000 9296 | 12:20 PM Florence Santa Maria Novella | 8h12 | 8:32 PM Lyon Part Dieu | 2 transfers | |
9924+ FRECCIAROSSA 1000 9296 | 12:25 PM Florence Santa Maria Novella | 8h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9514+ FRECCIAROSSA 1000 9296 | 12:55 PM Florence Santa Maria Novella | 7h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
9928+ FRECCIAROSSA 1000 9296 | 1:25 PM Florence Santa Maria Novella | 7h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Lyon Part Dieu by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Florence Santa Maria Novella to Lyon Part Dieu trains with Omio?
Why book with Omio vs Trenitalia?
- Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of Italo to find the best option for your trip from Florence Santa Maria Novella to Lyon Part Dieu.
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- Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Florence Santa Maria Novella to Lyon Part Dieu.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Florence Santa Maria Novella to Lyon Part Dieu.
Journey information
Overview: Train from Florence Santa Maria Novella to Lyon Part Dieu
Trains from Florence Santa Maria Novella to Lyon Part Dieu run on average 2 times per day, taking around 6h 39m. Cheap train tickets for this journey start at $153 (€123) but you can travel from only $19 (€15) by bus.
The earliest train runs at 10:55, the last at 10:55. The fastest train covers the 341 miles (550 km) distance in 7h 37m.
Distance 341 miles (550 km) |
Average train duration 6h 39m |
Cheapest ticket price $153 (€123) |
Trains per day 2 |
Fastest train 7h 37m |
First train 10:55 AM |
Last train 10:55 AM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Tue |
Train companies: Trenitalia, Italo from Florence Santa Maria Novella to Lyon Part Dieu trainsTrenitalia, Italo trains will get you between Florence Santa Maria Novella and Lyon Part Dieu from $19 (€15). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenitalia
Italo
FAQs: Trains from Florence Santa Maria Novella to Lyon Part Dieu
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Lyon Part Dieu by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon Part Dieu, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence Santa Maria Novella to Lyon Part Dieu
Most Florence Santa Maria Novella to Lyon Part Dieu trains use the Firenze Santa Maria Novella to Lyon Part Dieu station pair. Use this guide to compare Florence Santa Maria Novella and Lyon Part Dieu train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Firenze Santa Maria Novella from Florence city centre
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella train station facilities and services
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Wi-Fi and ATMs
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
Tickets and information
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Parking, taxis and toilets
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Bike and car services
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
Getting to Lyon Part Dieu from Lyon city centre
Lyon Part Dieu is 1 km from Lyon city centre. Public transport options include:
Lyon Part Dieu train station facilities and services
Lyon Part Dieu has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: Alto Café, Paul, Paul The Café, Starbucks, Exki, Sushi Shop, Carrefour
Wi-Fi and ATMs
Free unlimited WiFi. ATMs are located in the station's main hall.
Tickets and information
The ticket office is open Mon - Wed: 05:00 - 20:45, Thu - Sat: 05:00 - 21:45, Sun: 06:45 - 21:45. Information desks are located in the station's main hall. .
Luggage and lost property
Luggage storage is luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk. .
Parking, taxis and toilets
Available at Lyon Part Dieu: Parking, Taxis, WC.
Bike and car services
Available at Lyon Part Dieu: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Lyon Part Dieu: Complimentary personalized care is available.
Shops, hotels and contact
Nearby hotels include Radisson Blu Hotel Lyon, Mercure Lyon Center, ibis Styles Lyon Center.
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Lyon Part Dieu
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