Florence Santa Maria Novella to Lyon Part Dieu train with Trenitalia

Thu, May 28
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Deutsche Bahn
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The cheapest and fastest trains from Florence Santa Maria Novella to Lyon Part Dieu

Showing times and prices for May 28

Cheapest price

$202

Average price

$252

Fastest journey

7 h 7 m

Average duration

7 h 56 m

Trains per day

28

Distance

550 km

Cheap tickets

The best way to find a cheap train ticket from Florence Santa Maria Novella to Lyon Part Dieu is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence Santa Maria Novella to Lyon Part Dieu will cost around $252 if you buy it on the day, but the cheapest tickets can be found for only $202.

Fast trains

It's difficult to get from Florence Santa Maria Novella to Lyon Part Dieu without transferring at least once.

  • RegionaleRegionale 18654 · Regionale 17804 · Regionale Veloce TTPER 2462+TrenitaliaFRECCIAROSSA 1000 9296
    5:41 AM14h51
    Florence Santa Maria Novella
    8:32 PMLyon Part Dieu
    $2021One-way
    3 transfers
  • RegionaleRegionale 17800 · Regionale Veloce TTPER 2460+TrenitaliaFRECCIAROSSA 1000 9296
    4:32 AM16h00
    Florence Santa Maria Novella
    8:32 PMLyon Part Dieu
    $2021One-way
    2 transfers
  • RegionaleRegionale 18502 · Regionale 17808 · Regionale Veloce TTPER 2466+TrenitaliaFRECCIAROSSA 1000 9296
    7:09 AM13h23
    Florence Santa Maria Novella
    8:32 PMLyon Part Dieu
    $2021One-way
    3 transfers
  • IntercityIntercity 580+TrenitaliaFRECCIAROSSA 1000 9296
    8:21 AM12h11
    Florence Santa Maria Novella
    8:32 PMLyon Part Dieu
    $2151One-way
    1 transfer
  • RegionaleRegionale 18508 · Autobus FI680+IntercityIntercity 606+TrenitaliaFRECCIAROSSA 1000 9296
    9:09 AM11h23
    Florence Santa Maria Novella
    8:32 PMLyon Part Dieu
    $2171One-way
    3 transfers

Travel Information

Compare train, bus, and flight for Florence Santa Maria Novella to Lyon Part Dieu

Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Lyon Part Dieu among Omio's users. If you are prioritising price take the bus with prices starting from $19. For those with little time consider booking a flight which can get you there in 5h 2m. The ticket price range depends on the travel mode: a bus costs an average of $19, and a flight costs an average of $44.

Distance: 341 miles (550 km)

Compare train with

Most popular
Train
Bus
Flight
Driving

$118

Average price

$41

Average price

Cheapest

$180

Average price

$318

Average price

(fuel + tolls)

7h 8m

Average total duration

6h 38m

Onboard

+

30m

Additional time*

8h 58m

Average total duration

8h 28m

Onboard

+

30m

Additional time*

8h 2m

Average total duration

Fastest

5h 2m

Onboard

+

3h 0m

Additional time*

7h 24m

Average total duration

(door-to-door)

Trenitalia

Most popular train company

FlixBus

Most popular bus company

Air France

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence Santa Maria Novella to Lyon Part Dieu is a bus with an average price of $41 (€33).

This is compared to other travel options from Florence Santa Maria Novella to Lyon Part Dieu:

A bus is $77 (€62) less than a train for this route with tickets for a train from Florence Santa Maria Novella to Lyon Part Dieu costing on average $118 (€95).

A bus is $139 (€112) less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Lyon Part Dieu costing on average $180 (€146).

The fastest way to travel from Florence Santa Maria Novella to Lyon Part Dieu is by flight with an average journey time of 5h 2m.

Other travel options to Lyon Part Dieu take longer:

Train takes on average 6h 38m.

Bus takes on average 8h 28m.

It's helpful to compare your options as there are 3 ways to travel between Florence Santa Maria Novella and Lyon Part Dieu including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Lyon Part Dieu among Omio's users.
Take the train. On this route, it beats driving on both time and money.

The journey is about 46m faster (6h 38m by train vs 7h 24m by car) and roughly $200 (€161) cheaper once you factor in fuel and tolls ($118 (€95) vs $318 (€257)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.

Driving is still worth considering if you want to stop along the way or need a car once you arrive.

Live departures

Florence Santa Maria Novella to Lyon Part Dieu train times

The table below shows live departures for Florence Santa Maria Novella to Lyon Part Dieu trains for tomorrow, Thursday, May 28. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
RegionaleRegionale 18251+Intercity NotteInterCityNotte 796+RegionaleRegionale Veloce 3019+TrenitaliaFRECCIAROSSA 1000 929612:40 AM Florence Santa Maria Novella
19h52
8:32 PM Lyon Part Dieu3 transfers
RegionaleRegionale 17800 · Regionale Veloce TTPER 2460+TrenitaliaFRECCIAROSSA 1000 92964:32 AM Florence Santa Maria Novella
16h00
8:32 PM Lyon Part Dieu2 transfers
RegionaleRegionale 18654 · Regionale 17804 · Regionale Veloce TTPER 2462+TrenitaliaFRECCIAROSSA 1000 92965:41 AM Florence Santa Maria Novella
14h51
8:32 PM Lyon Part Dieu3 transfers
FrecciarossaFRECCIAROSSA 9504+TrenitaliaFRECCIAROSSA 1000 92966:55 AM Florence Santa Maria Novella
13h37
8:32 PM Lyon Part Dieu1 transfer
RegionaleRegionale 18502 · Regionale 17808 · Regionale Veloce TTPER 2466+TrenitaliaFRECCIAROSSA 1000 92967:09 AM Florence Santa Maria Novella
13h23
8:32 PM Lyon Part Dieu3 transfers
FrecciarossaFRECCIAROSSA 9400 · FRECCIAROSSA 9802+TrenitaliaFRECCIAROSSA 1000 92967:20 AM Florence Santa Maria Novella
13h12
8:32 PM Lyon Part Dieu2 transfers
Italo9904+TrenitaliaFRECCIAROSSA 1000 9296
On time
7:25 AM Florence Santa Maria Novella
13h07
8:32 PM Lyon Part Dieu
1 transfer
FrecciarossaFRECCIAROSSA 9508+TrenitaliaFRECCIAROSSA 1000 92967:55 AM Florence Santa Maria Novella
12h37
8:32 PM Lyon Part Dieu1 transfer
FrecciarossaFRECCIAROSSA 9404 · FRECCIAROSSA 9610+TrenitaliaFRECCIAROSSA 1000 92968:20 AM Florence Santa Maria Novella
12h12
8:32 PM Lyon Part Dieu2 transfers
IntercityIntercity 580+TrenitaliaFRECCIAROSSA 1000 92968:21 AM Florence Santa Maria Novella
12h11
8:32 PM Lyon Part Dieu1 transfer
Italo9908+TrenitaliaFRECCIAROSSA 1000 9296
On time
8:25 AM Florence Santa Maria Novella
12h07
8:32 PM Lyon Part Dieu
1 transfer
RegionaleRegionale 18466 · Regionale 17816 · Regionale Veloce TTPER 2470+TrenitaliaFRECCIAROSSA 1000 92968:37 AM Florence Santa Maria Novella
11h55
8:32 PM Lyon Part Dieu3 transfers
RegionaleRegionale 18466 · Regionale 17816+IntercityIntercity 604+TrenitaliaFRECCIAROSSA 1000 92968:37 AM Florence Santa Maria Novella
11h55
8:32 PM Lyon Part Dieu3 transfers
FrecciarossaFRECCIAROSSA 9512+TrenitaliaFRECCIAROSSA 1000 92968:55 AM Florence Santa Maria Novella
11h37
8:32 PM Lyon Part Dieu1 transfer
RegionaleRegionale 18508 · Autobus FI680+IntercityIntercity 606+TrenitaliaFRECCIAROSSA 1000 92969:09 AM Florence Santa Maria Novella
11h23
8:32 PM Lyon Part Dieu3 transfers
FrecciarossaFRECCIAROSSA 9406 · FRECCIAROSSA 9616+TrenitaliaFRECCIAROSSA 1000 92969:20 AM Florence Santa Maria Novella
11h12
8:32 PM Lyon Part Dieu2 transfers
Italo9912+TrenitaliaFRECCIAROSSA 1000 9296
On time
9:25 AM Florence Santa Maria Novella
11h07
8:32 PM Lyon Part Dieu
1 transfer
FrecciarossaFRECCIAROSSA 9516+TrenitaliaFRECCIAROSSA 1000 92969:55 AM Florence Santa Maria Novella
10h37
8:32 PM Lyon Part Dieu1 transfer
FrecciarossaFRECCIAROSSA 9490 · FRECCIAROSSA 8810+TrenitaliaFRECCIAROSSA 1000 929610:20 AM Florence Santa Maria Novella
10h12
8:32 PM Lyon Part Dieu2 transfers
Italo9916+TrenitaliaFRECCIAROSSA 1000 9296
On time
10:25 AM Florence Santa Maria Novella
10h07
8:32 PM Lyon Part Dieu
1 transfer
FrecciarossaFRECCIAROSSA 9520+TrenitaliaFRECCIAROSSA 1000 929610:55 AM Florence Santa Maria Novella
9h37
8:32 PM Lyon Part Dieu1 transfer
FrecciarossaFRECCIAROSSA 9414 · FRECCIAROSSA 9806+TrenitaliaFRECCIAROSSA 1000 929611:20 AM Florence Santa Maria Novella
9h12
8:32 PM Lyon Part Dieu2 transfers
Italo9920+TrenitaliaFRECCIAROSSA 1000 9296
On time
11:25 AM Florence Santa Maria Novella
9h07
8:32 PM Lyon Part Dieu
1 transfer
FrecciarossaFRECCIAROSSA 9524+TrenitaliaFRECCIAROSSA 1000 929611:55 AM Florence Santa Maria Novella
8h37
8:32 PM Lyon Part Dieu1 transfer
FrecciarossaFRECCIAROSSA 9416 · FRECCIAROSSA 8814+TrenitaliaFRECCIAROSSA 1000 929612:20 PM Florence Santa Maria Novella
8h12
8:32 PM Lyon Part Dieu2 transfers
Italo9924+TrenitaliaFRECCIAROSSA 1000 9296
On time
12:25 PM Florence Santa Maria Novella
8h07
8:32 PM Lyon Part Dieu
1 transfer
FrecciarossaFRECCIAROSSA 9514+TrenitaliaFRECCIAROSSA 1000 929612:55 PM Florence Santa Maria Novella
7h37
8:32 PM Lyon Part Dieu1 transfer
Italo9928+TrenitaliaFRECCIAROSSA 1000 9296
On time
1:25 PM Florence Santa Maria Novella
7h07
8:32 PM Lyon Part Dieu
1 transfer

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence Santa Maria Novella to Lyon Part Dieu by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
May 28
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May 30
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Mon
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Tue
Jun 02
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Jun 03

Why should you book Florence Santa Maria Novella to Lyon Part Dieu trains with Omio?

Trenitalia as well as Italo offer trains services from Florence Santa Maria Novella to Lyon Part Dieu.
Omio is an official ticket reseller for all your travel options from Florence Santa Maria Novella to Lyon Part Dieu.

Why book with Omio vs Trenitalia?

  • Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of Italo to find the best option for your trip from Florence Santa Maria Novella to Lyon Part Dieu.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Florence Santa Maria Novella to Lyon Part Dieu.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Florence Santa Maria Novella to Lyon Part Dieu.

Journey information

Overview: Train from Florence Santa Maria Novella to Lyon Part Dieu

ItalyItaly
FranceFrance
Icon of train

Trains from Florence Santa Maria Novella to Lyon Part Dieu run on average 1 times per day, taking around 6h 38m. Cheap train tickets for this journey start at $104 (€84) but you can travel from only $19 (€15) by bus.

The earliest train runs at 13:25, the last at 22:25. The fastest train covers the 341 miles (550 km) distance in 6h 53m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $19 (€15)
Distance
341 miles (550 km)
Average train duration
6h 38m
Cheapest ticket price
$104 (€84)
Trains per day
1
Fastest train
6h 53m
First train
1:25 PM
Last train
10:25 PM
Cheapest Month
Jun
Cheapest Day
Wed
High Season
Apr - Jun
Low Season
Jan - Mar
Busiest Day
Fri
Least Busy Day
Sat
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $19 (€15)

Train companies: Trenitalia, Italo from Florence Santa Maria Novella to Lyon Part Dieu trainsTrenitalia, Italo trains will get you between Florence Santa Maria Novella and Lyon Part Dieu from $19 (€15). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Trenitalia

About
Trenitalia is not only Italy's national railroad company but also the country's largest train operator. Trenitalia’s fleet of trains ncludes the high-speed Frecciarossa, Frecciargento and Frecciabianca trains as well as intercity, regional and night trains. Bathrooms and WiFi access are standard on long-distance routes. In most cases, the trains also provide barrier-free access. Trenitalia offers different tickets, which vary in price and flexibility: Base, Economy, Super Economy and Ordinaria. You can even use Trenitalia discount cards on Omio. Make sure to look out for the latest offers from Trenitalia on Omio to score special deals!
Luggage & cancellation policy
Trenitalia frequency
1 a day
Luggage included
2 pieces of hand luggage per passenger included in ticket price
Luggage storage
Overhead racks, luggage areas at end of carriages, and spaces between seat backs
Cancellation Policy
Cancellation policies vary by ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car on high-speed trains, trolley service with snacks and beverages, vending machines on some trains
Seat reservation
Optional seat reservation, costs extra except on high-speed trains where it's mandatory and included
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available with advance notice
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, guide dogs travel free
Quiet zone

Italo

About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Duration
6h 53m
Cheapest Price
$104 (€84)
Italo frequency
2 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone

FAQs: Trains from Florence Santa Maria Novella to Lyon Part Dieu

Find answers to the most common questions about traveling from Florence Santa Maria Novella to Lyon Part Dieu by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon Part Dieu, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Florence Santa Maria Novella to Lyon Part Dieu can vary. The cheapest ticket starts at $104 (€84), while the average price is around $118 (€95).
The train from Florence Santa Maria Novella to Lyon Part Dieu runs once a day and takes approximately 6h 53m.
The distance by train from Florence Santa Maria Novella to Lyon Part Dieu is 341 miles (550 km).
The first train from Florence Santa Maria Novella to Lyon Part Dieu leaves at 1:25 PM.
The last train from Florence Santa Maria Novella to Lyon Part Dieu leaves at 10:25 PM.
Yes, there is a high-speed train from Florence Santa Maria Novella to Lyon Part Dieu.
There is no direct train service currently available from Florence Santa Maria Novella to Lyon Part Dieu.
Unfortunately, there is no night train available from Florence Santa Maria Novella to Lyon Part Dieu.
The cheapest way to get from Florence Santa Maria Novella to Lyon Part Dieu is by bus, with a cost of around $19 (€15).
The train journey from Firenze Santa Maria Novella to Lyon Part Dieu offers a scenic experience, passing through picturesque Tuscan landscapes, the rolling hills of the Italian countryside, and the stunning Alps, providing travelers with a visually delightful trip.
A day trip from Firenze Santa Maria Novella to Lyon Part Dieu is not feasible as the journey takes 6h 53m, covering 341 miles (550 km). The frequency is 1 per day for trains.
Yes, you can take the train from Florence Santa Maria Novella to Lyon Part Dieu.
Since both Florence Santa Maria Novella and Lyon Part Dieu are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Lyon Part Dieu include Annecy, Saint-Étienne, Grenoble, Dijon, Montpellier.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Lyon Part Dieu among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
France uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most transactions, especially in cities and larger establishments, but carrying some cash is advisable for small vendors, markets, and rural areas where card acceptance may be limited.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Florence Santa Maria Novella to Lyon Part Dieu

Florence
Lyon
The major train station for departures in Florence is Firenze Santa Maria Novella. Find all the information you need to know about services, amenities and connections at Firenze Santa Maria Novella for your trip from Florence to Lyon.
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • Mon - Sun: 06:00 - 21:00
ticketOfficeHours
Distance to city center
1 km
Wifi
Wifi
  • Free WiFi (30 minutes limit).
Lockers
Lockers
  • Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Dining
Dining
  • 12oz Coffee Joint
  • Casa Maioli
  • Don Nino
  • Fratelli Cuore
  • McDonald´s
  • Panella
  • Segafredo Zanetti
  • Spizzico
  • Venchi
  • & many more
Accessibility
Accessibility
  • Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Hotel
Hotel
  • Hotel Luxor Florence
  • Joy Hotel Florence
  • Diplomat Hotel Florence
Ticket Office
Ticket Office
  • Mon - Sun: 06:00 - 21:00
Information Desk
Information Desk
  • Located inside and outside the station.
Public transit options for Firenze Santa Maria Novella
  • Tram lines: T1, T2
  • Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
  • Train lines: FR, FA, Italo

More options for your journey from Florence Santa Maria Novella to Lyon Part Dieu

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Most popular trains to and from Lyon Part Dieu and Florence Santa Maria Novella

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