Travel Information
Compare train, bus, and flight for Florence Santa Maria Novella to Lyon Part Dieu
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Lyon Part Dieu among Omio's users. If you are prioritising price take the bus with prices starting from €23. For those with little time consider booking a flight which can get you there in 1h 20m. The ticket price range depends on the travel mode: a bus costs an average of €23, and a flight costs an average of €29.
Distance: 341 miles (550 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€77 Average price | €57 Average price Cheapest | €149 Average price |
7h 9m Average total duration 6h 39m Onboard + 30m Additional time* | 10h 45m Average total duration 10h 15m Onboard + 30m Additional time* | 4h 20m Average total duration Fastest 1h 20m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Lyon Part Dieu train times
The table below shows live departures for Florence Santa Maria Novella to Lyon Part Dieu trains for today, Thursday, November 27. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
9912+ FRECCIAROSSA 1000 9296 | Delayed 8:28 AM 8:25 AMFlorence Santa Maria Novella | 11h07 | 7:32 PM Lyon Part Dieu | 1 transfer | |
9916+ FRECCIAROSSA 1000 9296 | Delayed 9:31 AM 9:25 AMFlorence Santa Maria Novella | 10h07 | 7:32 PM Lyon Part Dieu | 1 transfer | |
9920+ FRECCIAROSSA 1000 9296 | On time 10:25 AM Florence Santa Maria Novella | 9h07 | 7:32 PM Lyon Part Dieu | 1 transfer | |
9924+ FRECCIAROSSA 1000 9296 | 11:25 AM Florence Santa Maria Novella | 8h07 | 7:32 PM Lyon Part Dieu | 1 transfer | |
9928+ FRECCIAROSSA 1000 9296 | On time 12:25 PM Florence Santa Maria Novella | 7h07 | 7:32 PM Lyon Part Dieu | 1 transfer |
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Lyon Part Dieu by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Dec 03
Dec 04
Why should you book Florence Santa Maria Novella to Lyon Part Dieu trains with Omio?
Trenitalia as well as Italo offer trains services from Florence Santa Maria Novella to Lyon Part Dieu. Omio is an official ticket reseller for all your travel options from Florence Santa Maria Novella to Lyon Part Dieu.
Why book with Omio vs Trenitalia?
- Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of Italo to find the best option for your trip from Florence Santa Maria Novella to Lyon Part Dieu.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Florence Santa Maria Novella to Lyon Part Dieu.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Trenitalia tickets can be bought on Trenitalia's website or third party sellers, Omio allows you to compare with the likes of Italo to help you choose the right option for your journey from Florence Santa Maria Novella to Lyon Part Dieu.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Florence Santa Maria Novella to Lyon Part Dieu.
Journey information
Overview: Train from Florence Santa Maria Novella to Lyon Part Dieu
Trains from Florence Santa Maria Novella to Lyon Part Dieu run on average 1 times per day, taking around 6h 39m. Cheap train tickets for this journey start at $68 (€55) but you can travel from only $28 (€23) by bus.
The earliest train runs at 10:55, the last at 11:20. The fastest train covers the 341 miles (550 km) distance in 7h 12m.
Distance 341 miles (550 km) |
Average train duration 6h 39m |
Cheapest ticket price $68 (€55) |
Trains per day 1 |
Fastest train 7h 12m |
First train 10:55 |
Last train 11:20 |
Train companies: Trenitalia, Italo from Florence Santa Maria Novella to Lyon Part Dieu trainsTrenitalia, Italo trains will get you between Florence Santa Maria Novella and Lyon Part Dieu from $28 (€23). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenitalia
Italo
FAQs: Trains from Florence Santa Maria Novella to Lyon Part Dieu
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Lyon Part Dieu by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon Part Dieu, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence Santa Maria Novella to Lyon Part Dieu
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Free unlimited WiFi.
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
- Complimentary personalized care is available.
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Located in the station's main hall.
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Lyon Part Dieu
Here are some other resources that might have the information you need




