- Must visit
Vatican Museums
A vast complex of papal collections including classical sculpture, Renaissance masterpieces, the Raphael Rooms, and access to the Sistine Chapel. One of Rome’s most important art visits and often best
Omio recommends booking the bus as it is the most popular option from Siano to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $14. For those with little time consider booking a flight which can get you there in 57m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of $14, and a flight costs an average of $77.
Distance: 137 miles (221 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$21 Average price Cheapest | $120 Average price | $30 Average price | $74 Average price (fuel + tolls) |
4h 4m Average total duration 3h 34m Onboard + 30m Additional time* | 3h 57m Average total duration Fastest 57m Onboard + 3h 0m Additional time* | 4h 58m Average total duration 4h 28m Onboard + 30m Additional time* | 2h 42m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions | 0.7 - 1.3kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Siano to Rome:
A bus is $9 (€7) less than a train for this route with tickets for a train from Siano to Rome costing on average $30 (€24).
A bus is $99 (€80) less than a flight for this route with tickets for a flight from Siano to Rome costing on average $120 (€97).
Other travel options to Rome take longer:
Bus takes on average 3h 34m.
Train takes on average 4h 28m.
Tickets start at around $21 (€17) compared to roughly $74 (€60) in fuel and tolls — a saving of about $53 (€43). The journey takes 3h 34m versus 2h 42m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by TTI Leonettibus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Intersaj | Departure Time 12:33AM | Arrival Time 03:30AM | Duration 2h57 | Departure days Wed, Thu, Fri | Cheapest price $23 |
Operator Intersaj | Departure Time 07:55AM | Arrival Time 11:00AM | Duration 3h05 | Departure days Sat, Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 03:50PM | Arrival Time 06:45PM | Duration 2h55 | Departure days Fri | Cheapest price $23 |
Operator FlixBus | Departure Time 04:50PM | Arrival Time 07:45PM | Duration 2h55 | Departure days Wed, Thu, Fri | Cheapest price $14 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Siano to Rome run on average 29 times per day, taking around 3h 34m. Cheap bus tickets for this journey start at $14 (€11) if you book in advance.
There are 10 buses per day. The earliest bus runs at 02:33, the last at 23:50. The fastest bus covers the 137 miles (221 km) distance in 2h 55m.
Distance 137 miles (221 km) |
Average bus duration 3h 34m |
Cheapest ticket price $14 (€11) |
Buses per day 29 |
Direct buses 10 |
Fastest bus 2h 55m |
First bus 2:33 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
A vast complex of papal collections including classical sculpture, Renaissance masterpieces, the Raphael Rooms, and access to the Sistine Chapel. One of Rome’s most important art visits and often best
A superb villa museum with Bernini sculptures and paintings by Caravaggio, Raphael, and Titian. Timed entry is limited, making advance booking especially important.
The world’s oldest public museums, displaying Roman bronzes, ancient inscriptions, imperial sculpture, and excellent views over the Roman Forum from Capitoline Hill.
A grand baroque square with Bernini’s Fountain of the Four Rivers, elegant facades, and constant street life. One of Rome’s classic strolling areas.
A lively neighborhood of narrow lanes, ivy-covered buildings, and popular evening atmosphere. Very popular for wandering and photography, especially after sunset.
A famous monumental staircase linking Piazza di Spagna with Trinità dei Monti. A classic meeting point and one of the city’s most photographed urban scenes.
A classic Roman pasta made with pecorino romano and black pepper. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta with guanciale, egg yolk, pecorino romano, and black pepper. It is a defining dish of Rome and is traditionally made without cream.
A beloved pasta sauce of tomato, guanciale, and pecorino romano, usually served with bucatini. It is a cornerstone of Roman trattoria cooking.
Rome’s best-known luxury dining destination, offering fine dining, panoramic views, and an acclaimed tasting-menu experience by Heinz Beck.
A historic restaurant near the Pantheon celebrated for careful Roman cooking, including gricia, oxtail, and seasonal specialties, in a polished traditional space.
A famous central Rome dining room and delicatessen known for Roman pasta, cured meats, cheeses, and an exceptional wine list in a lively upscale setting.
Moderate by Western Europe standards: sights and central hotels cost more, while casual dining and transit stay reasonable.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave EUR 1-2 at cafes, 5-10% for great restaurant service, and round up taxis.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Find answers to the most common questions about traveling from Siano to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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