- Must visit
Museum of Byzantine Culture
Major state museum with outstanding Byzantine art, mosaics, icons, and everyday objects from early Christian to late Byzantine periods.
Cheapest price
$86
Average price
$96
Fastest journey
1 d 13 h 55 m
Average duration
1 d 15 h 47 m
Buses per day
10
Distance
1242 km
The best way to find a cheap bus ticket from Prague to Thessaloniki is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Thessaloniki will cost around $96 if you buy it on the day, but the cheapest tickets can be found for only $86.
It's difficult to get from Prague to Thessaloniki without transferring at least once.
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FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Prague to Thessaloniki among Omio's users. If you are prioritising price take the bus with prices starting from $88. For those with little time consider booking a flight which can get you there in 3h 14m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.1kg. The ticket price range depends on the travel mode: a bus costs an average of $88, and a flight costs an average of $122.
Distance: 771 miles (1242 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$169 Average price Cheapest | $239 Average price | $428 Average price (fuel + tolls) |
29h 33m Average total duration 29h 3m Onboard + 30m Additional time* | 6h 14m Average total duration Fastest 3h 14m Onboard + 3h 0m Additional time* | 15h 37m Average total duration (door-to-door) |
1.2 - 3.1kg CO2 emissions Lowest | 3.7 - 7.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Thessaloniki:
A bus is $70 (€57) less than a flight for this route with tickets for a flight from Prague to Thessaloniki costing on average $239 (€193).
Other travel options to Thessaloniki take longer:
Bus takes on average 29h 3m.
Tickets start at around $169 (€136) compared to roughly $428 (€346) in fuel and tolls — a saving of about $259 (€209). The journey takes 29h 3m versus 15h 37m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Infobus, Korona Travel, Korona Travel.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:50AM | Arrival Time 12:25PM | Duration 53h35 | Departure days Wed, Sat | Cheapest price $118 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 12:25PM | Duration 52h35 | Departure days Thu, Fri, Sat | Cheapest price $103 |
Operator FlixBus | Departure Time 07:20AM | Arrival Time 10:30PM | Duration 38h10 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $86 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 10:30PM | Duration 37h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $86 |
Operator FlixBus | Departure Time 07:50AM | Arrival Time 12:25PM | Duration 51h35 | Departure days Tue, Fri | Cheapest price $114 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 12:25PM | Duration 49h30 | Departure days Wed, Sat | Cheapest price $124 |
Operator FlixBus | Departure Time 11:25AM | Arrival Time 12:25PM | Duration 48h00 | Departure days Sat | Cheapest price $119 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 12:25PM | Duration 47h05 | Departure days Tue, Wed, Thu, Fri | Cheapest price $103 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 12:25PM | Duration 44h25 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $103 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 12:25PM | Duration 43h55 | Departure days Tue, Thu, Fri | Cheapest price $103 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 10:30PM | Duration 53h15 | Departure days Everyday | Cheapest price $89 |
Operator FlixBus | Departure Time 07:50PM | Arrival Time 12:25PM | Duration 39h35 | Departure days Thu | Cheapest price $102 |
Operator FlixBus | Departure Time 08:05PM | Arrival Time 12:25PM | Duration 39h20 | Departure days Wed, Thu, Sat | Cheapest price $102 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 12:25PM | Duration 38h25 | Departure days Wed, Sat | Cheapest price $116 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 12:25PM | Duration 38h15 | Departure days Wed, Sat | Cheapest price $119 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 10:30PM | Duration 46h45 | Departure days Everyday | Cheapest price $86 |
The table below shows live departures for Prague to Thessaloniki buses for today, Wednesday, June 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus · FlixBus | 9:55 AM Praha, Zličín | 49h30 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 12:20 PM Praha, Na Knížecí | 47h05 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
FlixBus · FlixBus · FlixBus | 3:00 PM Praha, Černý Most | 44h25 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 2 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 4:15 PM Praha, Černý Most | 53h15 | 10:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
FlixBus · FlixBus · FlixBus | 8:05 PM Prague, Central Train Station | 39h20 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Praha, Roztyly | 38h25 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 2 transfers | |
FlixBus · FlixBus | 9:10 PM Praha, ÚAN Florenc | 38h15 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 1 transfer | |
FlixBus · FlixBus · FlixBus · FlixBus | 10:45 PM Praha, Roztyly | 46h45 | 10:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
| Thursday, June 4 | |||||
FlixBus · FlixBus · FlixBus · FlixBus | 6:50 AM Praha, M. Horákové (Hradčanská) | 52h35 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Prague to Thessaloniki run on average 4 times per day, taking around 29h 3m. Cheap bus tickets for this journey start at $88 (€71) if you book in advance.
The earliest bus runs at 01:05, the last at 23:50. The fastest bus covers the 771 miles (1242 km) distance in 37h 55m.
Distance 771 miles (1242 km) |
Average bus duration 29h 3m |
Cheapest ticket price $88 (€71) |
Buses per day 4 |
Fastest bus 37h 55m |
First bus 1:05 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 1 day |
Discover the best of Thessaloniki — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Thessaloniki trip today.
Major state museum with outstanding Byzantine art, mosaics, icons, and everyday objects from early Christian to late Byzantine periods.
Essential museum covering ancient Macedonia, including gold grave goods, sculpture, and finds from prehistoric to Roman times.
Leading contemporary art museum in the Thessaloniki International Fair grounds, known for Greek and international modern works.
Thessaloniki’s grand central square facing the sea, lined with arcaded buildings and constantly active day and night.
Iconic promenade stretching along the Thermaic Gulf, ideal for walking, cycling, sunsets, and classic city views.
The old upper town with traditional houses, narrow lanes, viewpoints, and a more local, historic atmosphere.
A signature Thessaloniki pastry made with flaky phyllo, most famously filled with semolina custard, though cheese or minced meat versions are also common. It is one of the city’s most iconic breakfast
The city’s famous sesame bread ring, sold by street vendors and bakeries since Ottoman times. It is a simple, everyday snack strongly associated with Thessaloniki.
A local dessert from the Panorama area: crisp triangular phyllo pastries filled with rich cream. It is one of Thessaloniki’s best-known sweets and a classic local treat.
A long-running fine dining restaurant serving Greek and Mediterranean cuisine in an elegant setting, suitable for a more upscale meal.
A respected contemporary taverna known for expertly cooked seafood and seasonal Greek dishes. It has a simple, modern feel and a strong local reputation.
A well-known meze restaurant in Ladadika, popular for classic Greek small plates, seafood, and lively atmosphere in a historic setting.
Generally cheaper than Athens and many Western European cities. Dining and local transport are good value, while summer hotels in central areas cost more.
A tip is appreciated but not mandatory. Leave 5-10% in restaurants for good service, round up taxis, and small change is enough in cafes.
Official public transport app
Thessaloniki, Monastiriou - KTEL -> Aristotelous Square, Thessaloniki
Find answers to the most common questions about traveling from Prague to Thessaloniki by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Thessaloniki, this guide helps you travel smarter and with confidence.

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