- Must visit
Archaeological Museum of Thessaloniki
The city’s leading archaeology museum, presenting Macedonian gold, sculpture, and finds that explain Thessaloniki’s ancient history.





Cheapest price
$209
Average price
$234
Fastest journey
36h 20m
Average duration
39h 19m
Buses per day
5
Distance
180 km
Omio recommends booking the flight as it is the most popular option from Prague to Thessaloniki among Omio's users. If you are prioritising price take the bus with prices starting from $87. For those with little time consider booking a flight which can get you there in 3h 14m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.1kg. The ticket price range depends on the travel mode: a bus costs an average of $87, and a flight costs an average of $120.
Distance: 771 miles (1242 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$166 Average price Cheapest | $235 Average price | $421 Average price (fuel + tolls) |
29h 33m Average total duration 29h 3m Onboard + 30m Additional time* | 6h 14m Average total duration Fastest 3h 14m Onboard + 3h 0m Additional time* | 15h 37m Average total duration (door-to-door) |
1.2 - 3.1kg CO2 emissions Lowest | 3.7 - 7.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Thessaloniki:
A bus is $69 (€57) less than a flight for this route with tickets for a flight from Prague to Thessaloniki costing on average $235 (€193).
Other travel options to Thessaloniki take longer:
Bus takes on average 29h 3m.
Tickets start at around $166 (€136) compared to roughly $421 (€346) in fuel and tolls — a saving of about $255 (€209). The journey takes 29h 3m versus 15h 37m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Infobus, Korona Travel, Korona Travel.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:50AM | Arrival Time 04:50AM | Duration 46h00 | Departure days Thu, Sat | Cheapest price $121 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 04:50AM | Duration 45h00 | Departure days Everyday | Cheapest price $119 |
Operator FlixBus | Departure Time 07:20AM | Arrival Time 10:30PM | Duration 38h10 | Departure days Everyday | Cheapest price $113 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 10:30PM | Duration 37h55 | Departure days Everyday | Cheapest price $113 |
Operator FlixBus | Departure Time 07:50AM | Arrival Time 04:50AM | Duration 44h00 | Departure days Tue, Fri, Sat | Cheapest price $129 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 12:25PM | Duration 49h30 | Departure days Mon, Wed, Sat, Sun | Cheapest price $167 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 04:50AM | Duration 40h55 | Departure days Everyday | Cheapest price $117 |
Operator FlixBus | Departure Time 11:00AM | Arrival Time 04:50AM | Duration 40h50 | Departure days Wed, Thu | Cheapest price $151 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 04:50AM | Duration 36h50 | Departure days Mon, Tue, Fri, Sat | Cheapest price $119 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 04:50AM | Duration 36h20 | Departure days Tue, Fri, Sat | Cheapest price $119 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 12:25PM | Duration 38h25 | Departure days Mon, Wed, Sat, Sun | Cheapest price $139 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 12:25PM | Duration 38h15 | Departure days Mon, Wed, Sat, Sun | Cheapest price $138 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 10:30PM | Duration 46h45 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $109 |
The table below shows live departures for Prague to Thessaloniki buses for today, Saturday, July 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus · FlixBus | 3:00 PM Praha, Černý Most | 36h50 | 4:50 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 3:30 PM Praha, Roztyly | 36h20 | 4:50 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Praha, Roztyly | 38h25 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 2 transfers | |
FlixBus · FlixBus | 9:10 PM Praha, ÚAN Florenc | 38h15 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 1 transfer | |
FlixBus · FlixBus · FlixBus · FlixBus | 10:45 PM Praha, Roztyly | 46h45 | 10:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 6:50 AM Praha, M. Horákové (Hradčanská) | 52h35 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
FlixBus · FlixBus | 7:20 AM Praha, ÚAN Florenc | 38h10 | 10:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 1 transfer | |
FlixBus · FlixBus | 7:35 AM Prague, Central Train Station | 37h55 | 10:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 1 transfer | |
FlixBus · FlixBus · FlixBus · FlixBus | 9:55 AM Praha, Zličín | 49h30 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 3 transfers | |
FlixBus · FlixBus · FlixBus | 10:55 AM Praha, Na Knížecí | 48h30 | 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 2 transfers | |
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Prague to Thessaloniki run on average 4 times per day, taking around 29h 3m. Cheap bus tickets for this journey start at $87 (€71) if you book in advance.
The earliest bus runs at 01:05, the last at 23:50. The fastest bus covers the 771 miles (1242 km) distance in 37h 55m.
Distance 771 miles (1242 km) |
Average bus duration 29h 3m |
Cheapest ticket price $87 (€71) |
Buses per day 4 |
Fastest bus 37h 55m |
First bus 1:05 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 1 day |
Discover the best of Thessaloniki — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Thessaloniki trip today.
The city’s leading archaeology museum, presenting Macedonian gold, sculpture, and finds that explain Thessaloniki’s ancient history.
Major museum of Byzantine art with icons, mosaics, and everyday objects that illuminate a millennium of regional culture.
Housed in the White Tower, this museum traces Thessaloniki’s urban story through multimedia displays inside the landmark itself.
Signature waterfront promenade stretching along the sea, ideal for walking, cycling, sunset views, and seeing modern Thessaloniki at leisure.
The city’s central square and social heart, opening to the sea and lined with landmark architecture and major public events.
Historic upper town with traditional houses, winding lanes, and some of the best panoramic views in Thessaloniki.
Bougatsa is a flaky phyllo pastry filled with custard, cheese, or minced meat. Thessaloniki is especially famous for its breakfast bougatsa tradition.
Koulouri Thessalonikis is a sesame-crusted bread ring sold by street vendors. It is a classic local breakfast snack closely tied to the city's daily food culture.
Trigona Panoramatos are crisp syrupy phyllo triangles filled with rich custard cream. They originated in the Thessaloniki area and are a beloved local dessert.
Refined modern Greek restaurant known for creative plates, quality seafood, and a polished but relaxed setting in central Thessaloniki.
Historic pastry shop famed for classic bougatsa. A must for breakfast or dessert and one of the city's best-known traditional sweet stops.
Long-standing ladadika taverna serving meze, grilled dishes, and local wine in a lively traditional atmosphere popular with locals and visitors.
Moderate for Greece: rooms, meals, and buses are reasonable, with lower dining and transit costs than many Western European city breaks.
Service is usually included. Round up or leave 5-10% at restaurants for good service; round up taxi fares; small change is fine at cafes.
Official public transport app
Thessaloniki, Monastiriou - KTEL -> Aristotelous Square, Thessaloniki
Find answers to the most common questions about traveling from Prague to Thessaloniki by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Thessaloniki, this guide helps you travel smarter and with confidence.

Most Prague to Thessaloniki buses use the Praha, Roztyly to Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) station pair, with some services arriving at Thessaloniki (Θεσσαλονίκη). Use this guide to compare Prague and Thessaloniki bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) is 1 km from Thessaloniki city centre. Public transport options include:
Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ).
Available at Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ): Parking, Taxis, WC.
Accessibility facilities are available at Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ): Elevators, ramps.
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