Travel Information
Compare bus and flight for Prague to Thessaloniki
Omio recommends booking the flight as it is the most popular option from Prague to Thessaloniki among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €129 For those with little time, consider booking a flight, which has an average total journey time of 6h 29m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 1.2 - 3.1kg. Average ticket prices depend on the travel mode: a bus costs an average of €129, while a flight costs an average of €465.
Distance: 771 miles (1242 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
€465 Average price | €129 Average price Cheapest | €348 Average price (fuel + tolls) |
6h 29m Average total duration Fastest 4h 29m Onboard + 2h 0m Additional time* | 36h 58m Average total duration 36h 28m Onboard + 30m Additional time* | 15h 37m Average total duration (door-to-door) |
3.7 - 7.4kg CO2 emissions | 1.2 - 3.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Prague to Thessaloniki
Compare the available ways to get from Prague to Thessaloniki, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Prague to Thessaloniki:
A bus is €336 less than a flight for this route with tickets for a flight from Prague to Thessaloniki costing on average €465.
Other travel options to Thessaloniki take longer:
Bus takes on average 36h 58m.
You'll arrive about 11h 8m sooner (4h 29m by flight vs 15h 37m by car). Tickets start at around €465 compared to roughly €348 in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Prague to Thessaloniki
How to get from Prague to Thessaloniki by train, bus or flight.
Our recommendation
The best way to travel from Prague to Thessaloniki is by taking a flight because it’s the best combination of price and speed.
A3867 · A31027:50 PM 11h00 Prague Vaclav Havel Airport 7:50 AM Thessaloniki International Airport €117 1 One-way 1 transfer
Cheapest
A3867 · A31027:50 PM 11h00 Prague Vaclav Havel Airport 7:50 AM Thessaloniki International Airport €117 1 One-way 1 transfer
Fastest
OS644+
OS82311:00 AM 3h15 Prague Vaclav Havel Airport 3:15 PM Thessaloniki International Airport €262 1 One-way 1 transfer
Other options
FlixBus · FlixBus · FlixBus · FlixBus11:00 AM 48h25 Praha, Roztyly 12:25 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) €120 1 One-way 3 transfers
FlixBus · FlixBus · FlixBus · FlixBus4:15 PM 53h15 Praha, Černý Most 10:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) €121 1 One-way 3 transfers
FlixBus · FlixBus · FlixBus7:35 AM 37h55 Prague, Central Train Station 10:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) €121 1 One-way 2 transfers
A3867 · A31027:50 PM 11h00 Prague Vaclav Havel Airport 7:50 AM Thessaloniki International Airport €209 1 One-way 1 transfer
OS650+
OS8237:25 AM 6h50 Prague Vaclav Havel Airport 3:15 PM Thessaloniki International Airport €262 1 One-way 1 transfer
LH1693+
LH59264:45 PM 5h30 Prague Vaclav Havel Airport 11:15 PM Thessaloniki International Airport €285 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Prague to Thessaloniki
Travel to Thessaloniki easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Thessaloniki.

This is compared to other travel options from Prague to Thessaloniki:
A bus is €336 less than a flight for this route with tickets for a flight from Prague to Thessaloniki costing on average €465.
Other travel options to Thessaloniki take longer:
Bus takes on average 36h 58m.
- Around 38 flights per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Prague and Thessaloniki as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Thessaloniki International Airport.
- Buses mostly depart from Praha, Roztyly and arrive in Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ).
- Travel with FlixBus, Infobus, Korona Travel to go to Thessaloniki by bus.
- Travel with Turkish Airlines, Aegean Airlines, Lufthansa, Lot Polish Airlines, Austrian Airlines, Qatar Airways, Swiss, Air Baltic, Helvetic Airways, Smartwings, BA Euroflyer, British Airways, Eurowings, Avion Express Malta, TAP Portugal, Lufthansa Cityline, BA Cityflyer to go to Thessaloniki by flight.
- 0 direct buses per day with Infobus, Korona Travel.
- 0 direct flights per day with Smartwings.
Travelling from Prague to Thessaloniki: related information
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