- Must visit
National Museum
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
Cheapest price
$118
Average price
$124
Fastest journey
1 d 11 h
Average duration
1 d 15 h 35 m
Buses per day
10
Distance
1242 km
The best way to find a cheap bus ticket from Thessaloniki to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Thessaloniki to Prague will cost around $124 if you buy it on the day, but the cheapest tickets can be found for only $118.
It's difficult to get from Thessaloniki to Prague without transferring at least once.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Thessaloniki to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $82. For those with little time consider booking a flight which can get you there in 3h 22m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.1kg. The ticket price range depends on the travel mode: a bus costs an average of $82, and a flight costs an average of $95.
Distance: 771 miles (1242 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$143 Average price Cheapest | $228 Average price | $425 Average price (fuel + tolls) |
27h 41m Average total duration 27h 11m Onboard + 30m Additional time* | 6h 22m Average total duration Fastest 3h 22m Onboard + 3h 0m Additional time* | 15h 25m Average total duration (door-to-door) |
1.2 - 3.1kg CO2 emissions Lowest | 3.7 - 7.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Thessaloniki to Prague:
A bus is $85 (€69) less than a flight for this route with tickets for a flight from Thessaloniki to Prague costing on average $228 (€184).
Other travel options to Prague take longer:
Bus takes on average 27h 11m.
Tickets start at around $143 (€116) compared to roughly $425 (€345) in fuel and tolls — a saving of about $282 (€229). The journey takes 27h 11m versus 15h 25m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Infobus, Korona Travel.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:05AM | Arrival Time 04:45PM | Duration 40h40 | Departure days Fri, Sat, Sun | Cheapest price $110 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 06:45PM | Duration 37h25 | Departure days Mon | Cheapest price $194 |
Operator FlixBus | Departure Time 08:20AM | Arrival Time 08:55AM | Duration 49h35 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 06:00PM | Duration 51h30 | Departure days Mon | Cheapest price $127 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 01:55PM | Duration 45h25 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $102 |
The table below shows live departures for Thessaloniki to Prague buses for today, Tuesday, June 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus · FlixBus | 8:20 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 49h35 | 8:55 AM Praha, Na Knížecí | 3 transfers | |
FlixBus · FlixBus | 8:20 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 37h25 | 8:45 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus · FlixBus | 8:20 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 48h10 | 7:30 AM Praha, M. Horákové (Hradčanská) | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 8:20 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 43h05 | 2:25 AM Prague, Central Train Station | 3 transfers | |
FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 45h25 | 1:55 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 51h15 | 7:45 PM Praha, Na Knížecí | 3 transfers | |
FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 45h15 | 1:45 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 45h15 | 1:45 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 50h00 | 6:30 PM Praha, Zličín | 3 transfers | |
FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 44h50 | 1:20 PM Praha, Roztyly | 2 transfers | |
Find all the dates and times for this journey
Compare flight and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Thessaloniki to Prague run on average 4 times per day, taking around 27h 11m. Cheap bus tickets for this journey start at $82 (€66) if you book in advance.
The earliest bus runs at 01:05, the last at 23:50. The fastest bus covers the 771 miles (1242 km) distance in 34h 55m.
Distance 771 miles (1242 km) |
Average bus duration 27h 11m |
Cheapest ticket price $82 (€66) |
Buses per day 4 |
Fastest bus 34h 55m |
First bus 1:05 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Mon |
Best time to book 56 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
A significant museum complex preserving Jewish history and heritage through synagogues, ceremonial objects, and exhibitions in Josefov.
A highly regarded design museum with glass, ceramics, fashion, graphics, and decorative arts in a historic building near the Old Town.
Prague’s ceremonial heart, surrounded by historic facades, churches, and major landmarks; essential for first-time visitors.
A picturesque historic district below Prague Castle with baroque streets, embassies, gardens, and a romantic atmosphere.
A major boulevard-like square central to modern Czech history, shopping, and public life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the best-known classic Czech festive dishes.
Roast pork served with dumplings and braised cabbage. This is a cornerstone of traditional Czech home-style cooking and pub menus.
Czech-style goulash is usually a rich beef stew with onions, paprika, and bread dumplings. It is a hearty staple often eaten in historic Prague pubs.
Established traditional restaurant known for duck, old-Bohemian recipes, and elegant historic interiors. A strong choice for a refined Czech meal.
Well-known Old Town restaurant offering polished Czech classics and seasonal dishes in a stylish but approachable atmosphere.
A famous modern Czech beer hall serving classic dishes, fresh Pilsner, and dependable traditional cooking in a lively central setting.
Moderate by European standards. Beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip needed for counter service, though small change is appreciated.
Official public transport app
Praha Hlavní Nádraží, Prague -> Václavské Náměstí, Prague
Find answers to the most common questions about traveling from Thessaloniki to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need