- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
$159
Average price
$195
Fastest journey
1 d 13 h
Average duration
1 d 14 h 11 m
Buses per day
18
Distance
1242 km
The best way to find a cheap bus ticket from Thessaloniki to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Thessaloniki to Prague will cost around $195 if you buy it on the day, but the cheapest tickets can be found for only $159.
It's difficult to get from Thessaloniki to Prague without transferring at least once.
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FlixBus · FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Thessaloniki to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $81. For those with little time consider booking a flight which can get you there in 3h 22m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.1kg. The ticket price range depends on the travel mode: a bus costs an average of $81, and a flight costs an average of $94.
Distance: 771 miles (1242 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$142 Average price Cheapest | $226 Average price | $422 Average price (fuel + tolls) |
27h 41m Average total duration 27h 11m Onboard + 30m Additional time* | 6h 22m Average total duration Fastest 3h 22m Onboard + 3h 0m Additional time* | 15h 25m Average total duration (door-to-door) |
1.2 - 3.1kg CO2 emissions Lowest | 3.7 - 7.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Thessaloniki to Prague:
A bus is $84 (€69) less than a flight for this route with tickets for a flight from Thessaloniki to Prague costing on average $226 (€184).
Other travel options to Prague take longer:
Bus takes on average 27h 11m.
Tickets start at around $142 (€116) compared to roughly $422 (€345) in fuel and tolls — a saving of about $280 (€229). The journey takes 27h 11m versus 15h 25m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Infobus, Korona Travel.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:05AM | Arrival Time 10:50PM | Duration 46h45 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $132 |
Operator FlixBus | Departure Time 08:20AM | Arrival Time 02:25AM | Duration 43h05 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $148 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 10:05AM | Duration 41h35 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $136 |
The table below shows live departures for Thessaloniki to Prague buses for tomorrow, Saturday, August 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus · FlixBus | 1:05 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 41h45 | 5:50 PM Praha, Na Knížecí | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 1:05 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 42h25 | 6:30 PM Praha, Zličín | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 1:05 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 47h50 | 11:55 PM Prague, Central Train Station | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 1:05 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 45h25 | 9:30 PM Praha, Černý Most | 3 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 37h00 | 1:05 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 1:05 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 46h45 | 10:50 PM Praha, M. Horákové (Hradčanská) | 3 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 37h10 | 1:15 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 43h55 | 8:00 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 8:20 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 43h05 | 2:25 AM Prague, Central Train Station | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 8:20 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 48h10 | 7:30 AM Praha, M. Horákové (Hradčanská) | 3 transfers | |
FlixBus · FlixBus | 8:20 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 37h25 | 8:45 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 8:20 AM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 37h35 | 8:55 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 51h15 | 7:45 PM Praha, Na Knížecí | 3 transfers | |
FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 45h25 | 1:55 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 50h00 | 6:30 PM Praha, Zličín | 3 transfers | |
FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 44h50 | 1:20 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 45h15 | 1:45 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:30 PM Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) | 45h15 | 1:45 PM Praha, Černý Most | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare flight and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Thessaloniki to Prague run on average 4 times per day, taking around 27h 11m. Cheap bus tickets for this journey start at $81 (€66) if you book in advance.
The earliest bus runs at 01:05, the last at 23:50. The fastest bus covers the 771 miles (1242 km) distance in 34h 55m.
Distance 771 miles (1242 km) |
Average bus duration 27h 11m |
Cheapest ticket price $81 (€66) |
Buses per day 4 |
Fastest bus 34h 55m |
First bus 1:05 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Mon |
Best time to book 56 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Thessaloniki to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Thessaloniki to Prague buses use the Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Thessaloniki and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) is 1 km from Thessaloniki city centre. Public transport options include:
Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ).
Available at Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ): Parking, Taxis, WC.
Accessibility facilities are available at Thessaloniki, Monastiriou - KTEL (Θεσσαλονίκη, Μοναστηρίου - ΚΤΕΛ): Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Here are some other resources that might have the information you need